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The map label for this gene is relA [H]

Identifier: 189184318

GI number: 189184318

Start: 1447204

End: 1447491

Strand: Reverse

Name: relA [H]

Synonym: OTT_1411

Alternate gene names: 189184318

Gene position: 1447491-1447204 (Counterclockwise)

Preceding gene: 189184321

Following gene: 189184317

Centisome position: 72.05

GC content: 31.25

Gene sequence:

>288_bases
ATGATAGACTTTTATAGCGATAGCTTAATAAATAAGCTGTTTAGAACCAACGTAAAATTTAACACCAAAATTGATCTTGA
CAGAGTTGAAAAAGCAATATTTTATGCTAAAAAATATCATAGCAATCAAAAGCGAGATACAGGAGAACCATATTATATGC
ATCCATTAGAAGTAGCGCTCATGGTTGCAGACTACAGCTTTGAAACAGATACGATTATTACAGCAATACTACATGATACC
CTTGAAGATATAACACTAACCAAAGAAAAGATTGTTAAGGTATTTTGA

Upstream 100 bases:

>100_bases
ATAATTTAATTTGCTTCTTTTTCAGTTTTTATCTGGGATTGAAGTATACAAAAAGTTTAATTTATAGTATAATTTATTAA
AGATTATTTAGAGATGAAAA

Downstream 100 bases:

>100_bases
AAAAAAATTACGAAATAGGTTTCAGATCTCATCAGGATTAAGGATAATAAAAAAAAATCAGTTCTAGAGAAATGATTCAA
ACATTTTATAGCCAAAATAA

Product: RelA/SpoT-related protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MIDFYSDSLINKLFRTNVKFNTKIDLDRVEKAIFYAKKYHSNQKRDTGEPYYMHPLEVALMVADYSFETDTIITAILHDT
LEDITLTKEKIVKVF

Sequences:

>Translated_95_residues
MIDFYSDSLINKLFRTNVKFNTKIDLDRVEKAIFYAKKYHSNQKRDTGEPYYMHPLEVALMVADYSFETDTIITAILHDT
LEDITLTKEKIVKVF
>Mature_95_residues
MIDFYSDSLINKLFRTNVKFNTKIDLDRVEKAIFYAKKYHSNQKRDTGEPYYMHPLEVALMVADYSFETDTIITAILHDT
LEDITLTKEKIVKVF

Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Escherichia coli, GI1790082, Length=86, Percent_Identity=31.3953488372093, Blast_Score=59, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 11214; Mature: 11214

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFYSDSLINKLFRTNVKFNTKIDLDRVEKAIFYAKKYHSNQKRDTGEPYYMHPLEVAL
CCCCHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHEEE
MVADYSFETDTIITAILHDTLEDITLTKEKIVKVF
EHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure
MIDFYSDSLINKLFRTNVKFNTKIDLDRVEKAIFYAKKYHSNQKRDTGEPYYMHPLEVAL
CCCCHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHEEE
MVADYSFETDTIITAILHDTLEDITLTKEKIVKVF
EHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA