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The map label for this gene is rsh [H]

Identifier: 189184149

GI number: 189184149

Start: 1276297

End: 1276584

Strand: Reverse

Name: rsh [H]

Synonym: OTT_1242

Alternate gene names: 189184149

Gene position: 1276584-1276297 (Counterclockwise)

Preceding gene: 189184150

Following gene: 189184147

Centisome position: 63.54

GC content: 33.33

Gene sequence:

>288_bases
TTGAACTATGTTAACCAGTTTCGAAAGAGGGCTAATGTAAGATTTAACACCAAAATTGATCTTGATAGAGTTGAAAAAGC
AATATTTTATGCTAAAAAATATCATGGCCAGCAAAAGAGAGATACTGGAGAACTATACTACACACATCCATTAGAAGCAG
CACACATGGCTTCGGACCACAGCTTTGAAACAGATACGATTATTACAGCAATACTATATGATACACTAGAAGATACAACA
TTAACTAAAGAAAAAATTGCTAAAGTGTTTGGTAGTAACATTGCCTAA

Upstream 100 bases:

>100_bases
ATTTGTATGCTAAAACGGTTCAAAATTATTGCCGATAAATATCGAAATAGATGTAAAAGATTCTGTCTTAGATTTAATTT
GACCTCTGGCATTTATAATT

Downstream 100 bases:

>100_bases
TAATAAAACCGCAAAGGCAGATCAAGTATAAGGAAGAAGAAAAGTTAGTTTTTATTAACTTCTACACTTTATAGAACCTA
CTATTAACTTATGTTAACTT

Product: RelA/SpoT-related protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase [H]

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNYVNQFRKRANVRFNTKIDLDRVEKAIFYAKKYHGQQKRDTGELYYTHPLEAAHMASDHSFETDTIITAILYDTLEDTT
LTKEKIAKVFGSNIA

Sequences:

>Translated_95_residues
MNYVNQFRKRANVRFNTKIDLDRVEKAIFYAKKYHGQQKRDTGELYYTHPLEAAHMASDHSFETDTIITAILYDTLEDTT
LTKEKIAKVFGSNIA
>Mature_95_residues
MNYVNQFRKRANVRFNTKIDLDRVEKAIFYAKKYHGQQKRDTGELYYTHPLEAAHMASDHSFETDTIITAILYDTLEDTT
LTKEKIAKVFGSNIA

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Plays a role in ada

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 11062; Mature: 11062

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVNQFRKRANVRFNTKIDLDRVEKAIFYAKKYHGQQKRDTGELYYTHPLEAAHMASDH
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHCCCC
SFETDTIITAILYDTLEDTTLTKEKIAKVFGSNIA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNYVNQFRKRANVRFNTKIDLDRVEKAIFYAKKYHGQQKRDTGELYYTHPLEAAHMASDH
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHCCCC
SFETDTIITAILYDTLEDTTLTKEKIAKVFGSNIA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA