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The map label for this gene is ywlC [H]

Identifier: 189183849

GI number: 189183849

Start: 984104

End: 985072

Strand: Reverse

Name: ywlC [H]

Synonym: OTT_0942

Alternate gene names: 189183849

Gene position: 985072-984104 (Counterclockwise)

Preceding gene: 189183850

Following gene: 189183848

Centisome position: 49.03

GC content: 34.37

Gene sequence:

>969_bases
ATGTTAACAAATATGAACAGTAATAATAATGATATAAATGTTGCTGCACAATTTATTGAACAAGGGAAATTAGTCATATT
CCCTACTGAAACAGTGTATGGCATAGGGGCTGACGCAACTAACGATAATGCTTGTCAAAACATTTATAGAATCAAAAATA
GACCAACGAATAATCCATTGATTATTCATGTCAACAATATACAAGCTGCTCAAACTATAGGCATATTTAACAAGCTTGCT
ATTAAACTAGCAACCTTATGGCCAGGCCCAATTAGCTTAGTTGTACCACTTAATCAATCAGCAGGAATTAGCAGAACAGC
CACAGCAAATCTTGATACTGTAGCAATTAGAATTCCAGCTCATAAAACAGCTCTCACGTTGCTGCAATTAACACAAAAAC
CTATAGCTGCGCCAAGCGCAAACCCATCAGGTTATCTCAGCCCTACTACCTATCAGCATGCCAATATCCATTTCCAAAAT
TCTCCAAATACATTCATTCTTAAAGGCACTCAATCAACTTATGGATTAGAATCTACCATAATTGATACTACTACTGACAG
ACCAATAATATTACGCCATGGATTCATTACAACAGAAATAATAAAGACTATTACTGGACAAAACCCTATCATATCAAAAA
AACATAACAACTTTTTAAAAGCTCCAGGAATGATGTTAAAGCATTATTCTCCTATTACTAAAATTAGGTTAAATGCAACA
AAGCTTCTTCCAAAAGAAGTAGGATTAAATTATGGACCTAATACTCTAACTGGAAAATACTGCCTAAATCTTAGCCCAAA
CAGTAATTTAATGAATGCAGCAGCAAACTTATATCATATGCTTCATCAACTTGACAACTATGCACAAAATCCTATCAATG
AGGTTGAGACTATCGCCATAGCTCAAATACCAAATATAGGCATAGGAATTGCTATCAATGACAAGCTTAATCGCGCAAGA
TCATATTAA

Upstream 100 bases:

>100_bases
ACTACTGATCAGTGTCTTACTTATAATCGCAAGCTTATATTACAACATGTAGTACAGTGGTGCAATAATATAGCACCATT
TGACAAAGTAATAGAACATT

Downstream 100 bases:

>100_bases
CCCCAGAATAAGACAAGAGAAAGTATAAAAGGCATAGAAAAAAGATATACAAAGATAAAACGTTGAGTTACAAAGAAAAT
TTAAATAAAAATAAAATAAC

Product: Sua5/YciO/YrdC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLTNMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQNIYRIKNRPTNNPLIIHVNNIQAAQTIGIFNKLA
IKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPAHKTALTLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQN
SPNTFILKGTQSTYGLESTIIDTTTDRPIILRHGFITTEIIKTITGQNPIISKKHNNFLKAPGMMLKHYSPITKIRLNAT
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAIAQIPNIGIGIAINDKLNRAR
SY

Sequences:

>Translated_322_residues
MLTNMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQNIYRIKNRPTNNPLIIHVNNIQAAQTIGIFNKLA
IKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPAHKTALTLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQN
SPNTFILKGTQSTYGLESTIIDTTTDRPIILRHGFITTEIIKTITGQNPIISKKHNNFLKAPGMMLKHYSPITKIRLNAT
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAIAQIPNIGIGIAINDKLNRAR
SY
>Mature_322_residues
MLTNMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQNIYRIKNRPTNNPLIIHVNNIQAAQTIGIFNKLA
IKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPAHKTALTLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQN
SPNTFILKGTQSTYGLESTIIDTTTDRPIILRHGFITTEIIKTITGQNPIISKKHNNFLKAPGMMLKHYSPITKIRLNAT
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAIAQIPNIGIGIAINDKLNRAR
SY

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=167, Percent_Identity=26.9461077844311, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=248, Percent_Identity=37.0967741935484, Blast_Score=148, Evalue=9e-37,
Organism=Drosophila melanogaster, GI78707274, Length=144, Percent_Identity=34.7222222222222, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35249; Mature: 35249

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQNIYRIKNRPTNNPL
CCCCCCCCCCCHHHHHHHHHCCCEEEEECCEEEECCCCCCCCHHHHHHHHHCCCCCCCCE
IIHVNNIQAAQTIGIFNKLAIKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPA
EEEECCCCHHHHHHHHHHEEEEEEEECCCCEEEEEECCCCCCCCEEEECCCEEEEEEECC
HKTALTLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQNSPNTFILKGTQSTYGLESTI
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCCCCCCEEE
IDTTTDRPIILRHGFITTEIIKTITGQNPIISKKHNNFLKAPGMMLKHYSPITKIRLNAT
EECCCCCCEEEECCCHHHHHHHHHCCCCCEEECCCCCEECCCCHHHHHCCCCEEEEECHH
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAI
HHCHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEE
AQIPNIGIGIAINDKLNRARSY
EECCCCEEEEEECCCHHHHCCC
>Mature Secondary Structure
MLTNMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQNIYRIKNRPTNNPL
CCCCCCCCCCCHHHHHHHHHCCCEEEEECCEEEECCCCCCCCHHHHHHHHHCCCCCCCCE
IIHVNNIQAAQTIGIFNKLAIKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPA
EEEECCCCHHHHHHHHHHEEEEEEEECCCCEEEEEECCCCCCCCEEEECCCEEEEEEECC
HKTALTLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQNSPNTFILKGTQSTYGLESTI
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCCCCCCEEE
IDTTTDRPIILRHGFITTEIIKTITGQNPIISKKHNNFLKAPGMMLKHYSPITKIRLNAT
EECCCCCCEEEECCCHHHHHHHHHCCCCCEEECCCCCEECCCCHHHHHCCCCEEEEECHH
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAI
HHCHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEE
AQIPNIGIGIAINDKLNRARSY
EECCCCEEEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]