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The map label for this gene is slt [C]

Identifier: 189183499

GI number: 189183499

Start: 604732

End: 606729

Strand: Reverse

Name: slt [C]

Synonym: OTT_0592

Alternate gene names: 189183499

Gene position: 606729-604732 (Counterclockwise)

Preceding gene: 189183501

Following gene: 189183497

Centisome position: 30.2

GC content: 29.73

Gene sequence:

>1998_bases
ATGAAAATCATTAAGTTAACCTTTTTTACTGTTATTATCAATATTTATTTATTGTACTCAGTATGCGCTCAAGATTCCTA
TGAAAATATAACATATCAGCATCTAAGAAATAAACAGTGGAACGAAGCTGTATTGACAGCTGAAAATTCTGGCAATGAAA
TTTTATATAAGATAGCTTTAGCGCAAAAATTTCTGTATTCTGACACTGGCATAACATTTGAAGATATTATAGCTTTTTTA
CAAGCTAATCCAAATCATCCACAAAAAAATCATATAGCTAAACGCGCAGAAAAAGTTATTAATCATTTTACTGATCAAAA
CTTAATAATTAGATGGTTTAATAAAACCCCTCCTCAAACAGCTAAAGGCTATTATTATTATGCTTTAGCTGCTTATAAGC
TTATAACAGATTTGGACATAAGAAATAAGATAATACATACTGCCTGGAGGTTTTGCGATTCTGACTATATAATGCCTTTT
TTAGATAATTTTTGTGATTTGTTAACAACAGATGATTATTATGCTAAGATCACACAGTTTATATTAACAAATAAAATACC
TAATGCTAAAACTTTGTTAAGTAAGGCTGGCAAAAAAAAACTAAATCAACAAGTTTTGAATTTTATGATTGCAGCAGCTA
GTAATGATAATAATACAGAGAAATTATTTGCACAGTTACCAACAACTCAGCGTTATAAAAATGAAGTATTATATAGCATT
TTAACATATAAATTGAAAAATAATGATTATAGCTCTGAACTAGAACAACTTTTTTCTCAAGTTATAGAGTCAAAAATTAC
AGATAATTTTTTATTTTCTTCAAAATTATGGTGGCAATTACGATCAGAGGTTGCAAAAGGATTGCTAGCTACACATAATT
ACTCTGCTGCATATAATATTGTAAAGAATGCTATAGTGGATGATGTATATACTTCCATCGAACATAATTGGCTAGCTGGT
TGGATCGCTCTTAGGTTTTTACATAATTCAGCTAATGCTATTACTTATTTTACTAATATGGCACAACAAGTTACAAAACC
TATAGATATATCAAAATCATATTATTGGCTAGGTAGAGCTAATCAAGTAGCAGGAAACAGTCAAATTGCTCAGGATTATT
ATAAAAAAGCTACTCAGTATCCATATACCTTTTATGGACAATTAGCTATTCTTGAAACTGAGAATAAAGTGTTGCCACTA
TTCTCTGATTTGCAAATTAACATAGACAATATTGAGTTTAGCGATATTGAATGCGTAACAGCTTCTGAAATGTTACTAAG
TAATAATTTACCAGAATTATCAAAAATATATGCAGTACAAGCTATCAGGCATGCTTGTACTAATACTGAAATATATGCTA
TTATAAGCAGGCTAATTAATATAAAAGAATTATCTGGTATAAAAGACGTATCTTATGTTACAAAACTGATTAAATTTGCT
GAATGTGAAGCTTTATTTCCTACTCACTATTCTTATCCAACACCATATAACATGATAGATTCTCACATAGATAAGGACAT
ATTGTACAGCGTTATTATGCATGAATCAATGTTTGATCAATCGGTTATTGGAGCATCTAATGATCAAGGATTAATGCAGA
TAATGCCAGCAACAGCAAAAGATGTTGCTACTAAATTTCTAAAAATTCCATATGTGGCTACTAAGCTTATTACTGACCCT
AGTTATAATATTAAGCTTGGTAGCCACTACTGGAAAAGAATGCTAGATATTAATGATGGTTCATATGTACTAGCTACTGC
TTCATATAATGCTGGCCCATCTCGAGTTAGAGGTAGAAGAGGAATGAAGGGTTGGATAGAAATTTATGGTGATCCACGTA
AATATAAAGATGATAAGTATAAAGTGATTGATTGGATAGAAATTATTCCATCTGACAAACGAAATTATGTACAGAGAGTA
TTAGAAAATATCCATGTATACAGAACTATTCTTCATCAGCAGCGTAATGAAATATATTATATGGATTTCTTATTTTAA

Upstream 100 bases:

>100_bases
TCTTTTCCCATACCAACAAATTGTACTCCTTGACCAGGAAAAACAAATACTGTATACATAGATATTCTTTTGTATATATT
CCTAGAGTTGGATATTAAAT

Downstream 100 bases:

>100_bases
TTTAAACAAGAGTTTTATATAAAAAATAAGTTAAAATCTAGGTATAATAAGCGTAAAACCTATTACTATTCTAGTTAGAA
CTATATCGTGCTCAAATAAA

Product: soluble lytic murein transglycosylase precursor

Products: 1,6-Anhydrobond [C]

Alternate protein names: Soluble Lytic Murein Transglycosylase; Soluble Lytic Transglycosylase; Lytic Transglycosylase; Transglycosylase Slt Family; Transglycosylase SLT Domain Protein; Transglycosylase; Lytic Murein Transglycosylase; Slt Family Transglycosylase; Murein Transglycosylase Protein; Transglycosylase Slt Domain Protein; Lytic Murein Transglycosylase Soluble; Soluble Lytic Transglycosylase Domain-Containing Protein; Transglycosylase SLT Domain-Containing Protein; Transglycosylase SLT Family; Lytic Transglycosylase Catalytic Subunit; Peptidoglycan N-Acetylmuramoylhydrolase; Murein Transglycosylase; Soulbe Lytic Murein Transglycosylase; Lytic Murein Transglycosylase Family Protein; SLT Domain-Containing Protein

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MKIIKLTFFTVIINIYLLYSVCAQDSYENITYQHLRNKQWNEAVLTAENSGNEILYKIALAQKFLYSDTGITFEDIIAFL
QANPNHPQKNHIAKRAEKVINHFTDQNLIIRWFNKTPPQTAKGYYYYALAAYKLITDLDIRNKIIHTAWRFCDSDYIMPF
LDNFCDLLTTDDYYAKITQFILTNKIPNAKTLLSKAGKKKLNQQVLNFMIAAASNDNNTEKLFAQLPTTQRYKNEVLYSI
LTYKLKNNDYSSELEQLFSQVIESKITDNFLFSSKLWWQLRSEVAKGLLATHNYSAAYNIVKNAIVDDVYTSIEHNWLAG
WIALRFLHNSANAITYFTNMAQQVTKPIDISKSYYWLGRANQVAGNSQIAQDYYKKATQYPYTFYGQLAILETENKVLPL
FSDLQINIDNIEFSDIECVTASEMLLSNNLPELSKIYAVQAIRHACTNTEIYAIISRLINIKELSGIKDVSYVTKLIKFA
ECEALFPTHYSYPTPYNMIDSHIDKDILYSVIMHESMFDQSVIGASNDQGLMQIMPATAKDVATKFLKIPYVATKLITDP
SYNIKLGSHYWKRMLDINDGSYVLATASYNAGPSRVRGRRGMKGWIEIYGDPRKYKDDKYKVIDWIEIIPSDKRNYVQRV
LENIHVYRTILHQQRNEIYYMDFLF

Sequences:

>Translated_665_residues
MKIIKLTFFTVIINIYLLYSVCAQDSYENITYQHLRNKQWNEAVLTAENSGNEILYKIALAQKFLYSDTGITFEDIIAFL
QANPNHPQKNHIAKRAEKVINHFTDQNLIIRWFNKTPPQTAKGYYYYALAAYKLITDLDIRNKIIHTAWRFCDSDYIMPF
LDNFCDLLTTDDYYAKITQFILTNKIPNAKTLLSKAGKKKLNQQVLNFMIAAASNDNNTEKLFAQLPTTQRYKNEVLYSI
LTYKLKNNDYSSELEQLFSQVIESKITDNFLFSSKLWWQLRSEVAKGLLATHNYSAAYNIVKNAIVDDVYTSIEHNWLAG
WIALRFLHNSANAITYFTNMAQQVTKPIDISKSYYWLGRANQVAGNSQIAQDYYKKATQYPYTFYGQLAILETENKVLPL
FSDLQINIDNIEFSDIECVTASEMLLSNNLPELSKIYAVQAIRHACTNTEIYAIISRLINIKELSGIKDVSYVTKLIKFA
ECEALFPTHYSYPTPYNMIDSHIDKDILYSVIMHESMFDQSVIGASNDQGLMQIMPATAKDVATKFLKIPYVATKLITDP
SYNIKLGSHYWKRMLDINDGSYVLATASYNAGPSRVRGRRGMKGWIEIYGDPRKYKDDKYKVIDWIEIIPSDKRNYVQRV
LENIHVYRTILHQQRNEIYYMDFLF
>Mature_665_residues
MKIIKLTFFTVIINIYLLYSVCAQDSYENITYQHLRNKQWNEAVLTAENSGNEILYKIALAQKFLYSDTGITFEDIIAFL
QANPNHPQKNHIAKRAEKVINHFTDQNLIIRWFNKTPPQTAKGYYYYALAAYKLITDLDIRNKIIHTAWRFCDSDYIMPF
LDNFCDLLTTDDYYAKITQFILTNKIPNAKTLLSKAGKKKLNQQVLNFMIAAASNDNNTEKLFAQLPTTQRYKNEVLYSI
LTYKLKNNDYSSELEQLFSQVIESKITDNFLFSSKLWWQLRSEVAKGLLATHNYSAAYNIVKNAIVDDVYTSIEHNWLAG
WIALRFLHNSANAITYFTNMAQQVTKPIDISKSYYWLGRANQVAGNSQIAQDYYKKATQYPYTFYGQLAILETENKVLPL
FSDLQINIDNIEFSDIECVTASEMLLSNNLPELSKIYAVQAIRHACTNTEIYAIISRLINIKELSGIKDVSYVTKLIKFA
ECEALFPTHYSYPTPYNMIDSHIDKDILYSVIMHESMFDQSVIGASNDQGLMQIMPATAKDVATKFLKIPYVATKLITDP
SYNIKLGSHYWKRMLDINDGSYVLATASYNAGPSRVRGRRGMKGWIEIYGDPRKYKDDKYKVIDWIEIIPSDKRNYVQRV
LENIHVYRTILHQQRNEIYYMDFLF

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 77122; Mature: 77122

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIKLTFFTVIINIYLLYSVCAQDSYENITYQHLRNKQWNEAVLTAENSGNEILYKIAL
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECCCCCEEEEHHHH
AQKFLYSDTGITFEDIIAFLQANPNHPQKNHIAKRAEKVINHFTDQNLIIRWFNKTPPQT
HHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
AKGYYYYALAAYKLITDLDIRNKIIHTAWRFCDSDYIMPFLDNFCDLLTTDDYYAKITQF
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
ILTNKIPNAKTLLSKAGKKKLNQQVLNFMIAAASNDNNTEKLFAQLPTTQRYKNEVLYSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
LTYKLKNNDYSSELEQLFSQVIESKITDNFLFSSKLWWQLRSEVAKGLLATHNYSAAYNI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VKNAIVDDVYTSIEHNWLAGWIALRFLHNSANAITYFTNMAQQVTKPIDISKSYYWLGRA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCC
NQVAGNSQIAQDYYKKATQYPYTFYGQLAILETENKVLPLFSDLQINIDNIEFSDIECVT
CCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEECCCCEECEECCCEEEECCEEECCEEEEH
ASEMLLSNNLPELSKIYAVQAIRHACTNTEIYAIISRLINIKELSGIKDVSYVTKLIKFA
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ECEALFPTHYSYPTPYNMIDSHIDKDILYSVIMHESMFDQSVIGASNDQGLMQIMPATAK
HCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHH
DVATKFLKIPYVATKLITDPSYNIKLGSHYWKRMLDINDGSYVLATASYNAGPSRVRGRR
HHHHHHHHCCHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCC
GMKGWIEIYGDPRKYKDDKYKVIDWIEIIPSDKRNYVQRVLENIHVYRTILHQQRNEIYY
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
MDFLF
EEEEC
>Mature Secondary Structure
MKIIKLTFFTVIINIYLLYSVCAQDSYENITYQHLRNKQWNEAVLTAENSGNEILYKIAL
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECCCCCEEEEHHHH
AQKFLYSDTGITFEDIIAFLQANPNHPQKNHIAKRAEKVINHFTDQNLIIRWFNKTPPQT
HHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
AKGYYYYALAAYKLITDLDIRNKIIHTAWRFCDSDYIMPFLDNFCDLLTTDDYYAKITQF
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
ILTNKIPNAKTLLSKAGKKKLNQQVLNFMIAAASNDNNTEKLFAQLPTTQRYKNEVLYSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
LTYKLKNNDYSSELEQLFSQVIESKITDNFLFSSKLWWQLRSEVAKGLLATHNYSAAYNI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VKNAIVDDVYTSIEHNWLAGWIALRFLHNSANAITYFTNMAQQVTKPIDISKSYYWLGRA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCC
NQVAGNSQIAQDYYKKATQYPYTFYGQLAILETENKVLPLFSDLQINIDNIEFSDIECVT
CCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEECCCCEECEECCCEEEECCEEECCEEEEH
ASEMLLSNNLPELSKIYAVQAIRHACTNTEIYAIISRLINIKELSGIKDVSYVTKLIKFA
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ECEALFPTHYSYPTPYNMIDSHIDKDILYSVIMHESMFDQSVIGASNDQGLMQIMPATAK
HCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHH
DVATKFLKIPYVATKLITDPSYNIKLGSHYWKRMLDINDGSYVLATASYNAGPSRVRGRR
HHHHHHHHCCHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCC
GMKGWIEIYGDPRKYKDDKYKVIDWIEIIPSDKRNYVQRVLENIHVYRTILHQQRNEIYY
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
MDFLF
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA