| Definition | Orientia tsutsugamushi str. Ikeda, complete genome. |
|---|---|
| Accession | NC_010793 |
| Length | 2,008,987 |
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The map label for this gene is ppdK [H]
Identifier: 189183297
GI number: 189183297
Start: 405184
End: 407889
Strand: Reverse
Name: ppdK [H]
Synonym: OTT_0390
Alternate gene names: 189183297
Gene position: 407889-405184 (Counterclockwise)
Preceding gene: 189183301
Following gene: 189183295
Centisome position: 20.3
GC content: 31.86
Gene sequence:
>2706_bases ATGACAAAGTGGATTTATCGATTTTCAAGTACGTCTGCAAACTTACCTCATATTAATTCAGTAGACCAATCATGTAATAT AATGAAAGATAATCTGCAAAGTCTACTCGGTAACAAAGGTGTAACACTTGCTCAGATGTTTAGTCAAAAACTACCTATAC CGCATGGTTTTATTATATCAACTAAATTATATCATTACTATCAGCAAAATAATGATTCTCTACCAAGTGATTTCATATCT GATTTAAAATCATCTATTCTAGATTTAGAACATCAAACTGGAAAAAATTTTGGTGATTATAATAATCCGCTATTAGTTGC AGTAAGGTCTAGTGCTGCAGTATCCATGCCTGGAATTATGAACACTATACTTAATCTAGGTATAAATGATATTATAGTTG AAGGGTTAAGTACCGTAACAGGTAATAGAATTTTTGCATTAGATACTTATATGCGTTTTATTCAAACTTATGGACAAGTA GTTATGGGAGTATCACCTGCAGAATTTGAACTTGCTTTAAATCAGTTTAAAACATTAAATAATATTACTAGTCAAGAACA GCTAACTTCAGAACATTTACATAATCTAATTACAATTTTTAAGCAAATTATTCATAAAGAAACTAAACAAAAATTTCCAC AAGATGTTAATATTCAATTACACCAAGCTATTCAAGCAGTATTAAAATCATGGATGAACCACCATGCTATTACATATAGA AAACTTAACAATATTTCAGGTAATATTGGAACTGCTATTATTGTGCAAACTATGGTTTTTGGTAATATGGGTAGTGATTC AGCAACAGGAGTAGTGTTTACTAGAAACCCTTTAACAGGGGATAATAAACTATATGGCGAATTTTTAATTAATGCTCAAG GAGATAACGTTGTATCTGGAGCTAGTATACCTAATTCCATATTAAGTGATAATAAGGATCAAAAATGCACCTTAAAGTAT GCTATGCATAAGATGTATGAAGAGTTATTACAGCATTGCAAACAATTGGAACAGCATTACTGTAATATTCAAGATATCGA ATTTACTATAGAAAAGCAAAAATTATATATATTACAGACAAGATCTGCAAAATGCACAGCATTAGCAACTATCAAGGCAC TAGTAGATATGGTCGCCTCTGGGTTAATAACTAAAAAAGAAGCGATAGCTAAAATCAATCCAATGTCACTCAATCAACTA CTACACTCATATATTGATGAAAGTGAGAATTATAAAGTAATAACTCAAGGACTTCCATCTACACCAGGAGCTGTAACTGG AGTAATTGCATTATCAGTAGCTGCTGCTGAAAAATTATCTAATCAACATCATAAAGTGATTTTTATATGTTCAAATATTA GTCCTGAAGACATTAAAGCTATGCATATATCTTCTGGTATTTTAACTAGTGGTGGAAATACAACTTCTCATGCAGCAATT CTTAGCAGAGCATTAGGAAAGCCACATATTTGTGCTGCTAAAGATGTTATAATTGACCAACAGAACGGACTGATAAAAAT AGGCGATATTAGTTTGTATCAAGGCAGTAAAATTACCATAGATGGTAACAGTGGTAAAGTATTTGTAGGAGACGTAAGAT TACTACAGCCAGAGTTTTCTAAGGAATGTCAATTATTTATGGAGTGGGCTGATGAAATAAAAACAGTTGAGGTAAAGGCT AATGCAGATACTAGCGATGATGTAAAATTAGCACTGCGACTTGGGGCAACATCTATCGGTCTTTGCCGTACTGAGCATAT GCTTCTTGAGGACAACAAAATCAGCTTAGTTCAGGAGACAATTATTGCTGATAATGATCAATGTAGATTGAATGCGCTTA AAAGACTGTTTTTGTTGCATAAAGCTGATTTTAAAGAGCTATTTGCTGCTACAATGCAAATCCCAATTAATATCAGGCTA CTTGACGCACCATTACATGAATTTTTACCTACAACATTTACAACTGCACACAATAGAATCATAGATAATCTAAACATTTC TCAAGAAACGTTTAATGCAAGAATTAACACGTTAAAGGAAGTTAATCCTATGTTGGGTCATAGAGGTTGTAGAATCGGTA TAAGTTTTCCTGAGATTTATGAAATGCAGGTTCGAGCAATATTTGAAGCTGCAGCTGAAATATTACTTGAGTTAAAAGTT ATGCCTAAAATTGAAGTTACTATACCATTAATTAGCCATAAAAAAGAGTTGCAATTGTTAAAGCGAATAATTTATAAAAT AGTAGAAAAAGTAGAACAGCAAAAATTACTTAAATATAGATGTAAGTTTGATTATACAATAGGAACTATGATTGAATTGC CTAGAGCCGCTCTTCAGGCATATGAACTGGCTCAGGAAGTGGATTTTTTCTGTTTTGGTACTAACGATTTAACGCAAACT ACATATGGTATTTCAAGAGATGATTCTACATCTTTTATTAATCAGTATATTGAAAATGATATTTTTACAGCTGATCCTTT TACAACTTTAGATTGTGAGGCTGTAGGAGAATTAATTCAAATAGCCATTGAACGTGGCCGAACTGCTAAAAAACATCTTA AAATAGGAATTTGTGGTGAACATGCTGCTGATTCAAATTCAGTAGAATTTTTTCATAAAGTTAAAGTAGATTCAATATCA TGTTCGCCATATAAAATTCCAATTGCTAGATTAGCAGCAGCACAAGCAGCATTAAAAAATAATTAA
Upstream 100 bases:
>100_bases TTAAATTAATTAAGCATAAAATTAATAACTTTGAAAATAACATGACCTAACTTAATAATTAGTTTATGCAAATACTATAC AATCATTTAGAGGCAATATT
Downstream 100 bases:
>100_bases CTACGAGTTAGATATAAGAAATAATGTAAAATCTAGATAGAAGAAATATTATAGCTCTTTTTATGCTTATAGCTTAATTC GAGAAGGTAGTTGCAATTGT
Product: pyruvate phosphate dikinase
Products: NA
Alternate protein names: Pyruvate, orthophosphate dikinase [H]
Number of amino acids: Translated: 901; Mature: 900
Protein sequence:
>901_residues MTKWIYRFSSTSANLPHINSVDQSCNIMKDNLQSLLGNKGVTLAQMFSQKLPIPHGFIISTKLYHYYQQNNDSLPSDFIS DLKSSILDLEHQTGKNFGDYNNPLLVAVRSSAAVSMPGIMNTILNLGINDIIVEGLSTVTGNRIFALDTYMRFIQTYGQV VMGVSPAEFELALNQFKTLNNITSQEQLTSEHLHNLITIFKQIIHKETKQKFPQDVNIQLHQAIQAVLKSWMNHHAITYR KLNNISGNIGTAIIVQTMVFGNMGSDSATGVVFTRNPLTGDNKLYGEFLINAQGDNVVSGASIPNSILSDNKDQKCTLKY AMHKMYEELLQHCKQLEQHYCNIQDIEFTIEKQKLYILQTRSAKCTALATIKALVDMVASGLITKKEAIAKINPMSLNQL LHSYIDESENYKVITQGLPSTPGAVTGVIALSVAAAEKLSNQHHKVIFICSNISPEDIKAMHISSGILTSGGNTTSHAAI LSRALGKPHICAAKDVIIDQQNGLIKIGDISLYQGSKITIDGNSGKVFVGDVRLLQPEFSKECQLFMEWADEIKTVEVKA NADTSDDVKLALRLGATSIGLCRTEHMLLEDNKISLVQETIIADNDQCRLNALKRLFLLHKADFKELFAATMQIPINIRL LDAPLHEFLPTTFTTAHNRIIDNLNISQETFNARINTLKEVNPMLGHRGCRIGISFPEIYEMQVRAIFEAAAEILLELKV MPKIEVTIPLISHKKELQLLKRIIYKIVEKVEQQKLLKYRCKFDYTIGTMIELPRAALQAYELAQEVDFFCFGTNDLTQT TYGISRDDSTSFINQYIENDIFTADPFTTLDCEAVGELIQIAIERGRTAKKHLKIGICGEHAADSNSVEFFHKVKVDSIS CSPYKIPIARLAAAQAALKNN
Sequences:
>Translated_901_residues MTKWIYRFSSTSANLPHINSVDQSCNIMKDNLQSLLGNKGVTLAQMFSQKLPIPHGFIISTKLYHYYQQNNDSLPSDFIS DLKSSILDLEHQTGKNFGDYNNPLLVAVRSSAAVSMPGIMNTILNLGINDIIVEGLSTVTGNRIFALDTYMRFIQTYGQV VMGVSPAEFELALNQFKTLNNITSQEQLTSEHLHNLITIFKQIIHKETKQKFPQDVNIQLHQAIQAVLKSWMNHHAITYR KLNNISGNIGTAIIVQTMVFGNMGSDSATGVVFTRNPLTGDNKLYGEFLINAQGDNVVSGASIPNSILSDNKDQKCTLKY AMHKMYEELLQHCKQLEQHYCNIQDIEFTIEKQKLYILQTRSAKCTALATIKALVDMVASGLITKKEAIAKINPMSLNQL LHSYIDESENYKVITQGLPSTPGAVTGVIALSVAAAEKLSNQHHKVIFICSNISPEDIKAMHISSGILTSGGNTTSHAAI LSRALGKPHICAAKDVIIDQQNGLIKIGDISLYQGSKITIDGNSGKVFVGDVRLLQPEFSKECQLFMEWADEIKTVEVKA NADTSDDVKLALRLGATSIGLCRTEHMLLEDNKISLVQETIIADNDQCRLNALKRLFLLHKADFKELFAATMQIPINIRL LDAPLHEFLPTTFTTAHNRIIDNLNISQETFNARINTLKEVNPMLGHRGCRIGISFPEIYEMQVRAIFEAAAEILLELKV MPKIEVTIPLISHKKELQLLKRIIYKIVEKVEQQKLLKYRCKFDYTIGTMIELPRAALQAYELAQEVDFFCFGTNDLTQT TYGISRDDSTSFINQYIENDIFTADPFTTLDCEAVGELIQIAIERGRTAKKHLKIGICGEHAADSNSVEFFHKVKVDSIS CSPYKIPIARLAAAQAALKNN >Mature_900_residues TKWIYRFSSTSANLPHINSVDQSCNIMKDNLQSLLGNKGVTLAQMFSQKLPIPHGFIISTKLYHYYQQNNDSLPSDFISD LKSSILDLEHQTGKNFGDYNNPLLVAVRSSAAVSMPGIMNTILNLGINDIIVEGLSTVTGNRIFALDTYMRFIQTYGQVV MGVSPAEFELALNQFKTLNNITSQEQLTSEHLHNLITIFKQIIHKETKQKFPQDVNIQLHQAIQAVLKSWMNHHAITYRK LNNISGNIGTAIIVQTMVFGNMGSDSATGVVFTRNPLTGDNKLYGEFLINAQGDNVVSGASIPNSILSDNKDQKCTLKYA MHKMYEELLQHCKQLEQHYCNIQDIEFTIEKQKLYILQTRSAKCTALATIKALVDMVASGLITKKEAIAKINPMSLNQLL HSYIDESENYKVITQGLPSTPGAVTGVIALSVAAAEKLSNQHHKVIFICSNISPEDIKAMHISSGILTSGGNTTSHAAIL SRALGKPHICAAKDVIIDQQNGLIKIGDISLYQGSKITIDGNSGKVFVGDVRLLQPEFSKECQLFMEWADEIKTVEVKAN ADTSDDVKLALRLGATSIGLCRTEHMLLEDNKISLVQETIIADNDQCRLNALKRLFLLHKADFKELFAATMQIPINIRLL DAPLHEFLPTTFTTAHNRIIDNLNISQETFNARINTLKEVNPMLGHRGCRIGISFPEIYEMQVRAIFEAAAEILLELKVM PKIEVTIPLISHKKELQLLKRIIYKIVEKVEQQKLLKYRCKFDYTIGTMIELPRAALQAYELAQEVDFFCFGTNDLTQTT YGISRDDSTSFINQYIENDIFTADPFTTLDCEAVGELIQIAIERGRTAKKHLKIGICGEHAADSNSVEFFHKVKVDSISC SPYKIPIARLAAAQAALKNN
Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate [H]
COG id: COG0574
COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PEP-utilizing enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1788756, Length=460, Percent_Identity=25.8695652173913, Blast_Score=118, Evalue=2e-27, Organism=Escherichia coli, GI48994992, Length=446, Percent_Identity=25.7847533632287, Blast_Score=101, Evalue=2e-22, Organism=Escherichia coli, GI1788726, Length=640, Percent_Identity=20.9375, Blast_Score=94, Evalue=3e-20, Organism=Escherichia coli, GI1789193, Length=417, Percent_Identity=25.4196642685851, Blast_Score=91, Evalue=4e-19,
Paralogues:
None
Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013815 - InterPro: IPR013816 - InterPro: IPR008279 - InterPro: IPR018274 - InterPro: IPR023151 - InterPro: IPR000121 - InterPro: IPR002192 - InterPro: IPR010121 - InterPro: IPR015813 [H]
Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]
EC number: =2.7.9.1 [H]
Molecular weight: Translated: 100474; Mature: 100343
Theoretical pI: Translated: 7.19; Mature: 7.19
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKWIYRFSSTSANLPHINSVDQSCNIMKDNLQSLLGNKGVTLAQMFSQKLPIPHGFIIS CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEH TKLYHYYQQNNDSLPSDFISDLKSSILDLEHQTGKNFGDYNNPLLVAVRSSAAVSMPGIM HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHH NTILNLGINDIIVEGLSTVTGNRIFALDTYMRFIQTYGQVVMGVSPAEFELALNQFKTLN HHHHHCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH NITSQEQLTSEHLHNLITIFKQIIHKETKQKFPQDVNIQLHQAIQAVLKSWMNHHAITYR HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEE KLNNISGNIGTAIIVQTMVFGNMGSDSATGVVFTRNPLTGDNKLYGEFLINAQGDNVVSG HHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEC ASIPNSILSDNKDQKCTLKYAMHKMYEELLQHCKQLEQHYCNIQDIEFTIEKQKLYILQT CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEE RSAKCTALATIKALVDMVASGLITKKEAIAKINPMSLNQLLHSYIDESENYKVITQGLPS CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCC TPGAVTGVIALSVAAAEKLSNQHHKVIFICSNISPEDIKAMHISSGILTSGGNTTSHAAI CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCEEECCCCCHHHHHH LSRALGKPHICAAKDVIIDQQNGLIKIGDISLYQGSKITIDGNSGKVFVGDVRLLQPEFS HHHHCCCCCCEECCCEEEECCCCEEEEECEEEECCCEEEEECCCCEEEEECEEEECCCHH KECQLFMEWADEIKTVEVKANADTSDDVKLALRLGATSIGLCRTEHMLLEDNKISLVQET HHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCHHCCCCEEECCCCHHHHHHH IIADNDQCRLNALKRLFLLHKADFKELFAATMQIPINIRLLDAPLHEFLPTTFTTAHNRI HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCHHHHCCCHHHHHHHHH IDNLNISQETFNARINTLKEVNPMLGHRGCRIGISFPEIYEMQVRAIFEAAAEILLELKV HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHC MPKIEVTIPLISHKKELQLLKRIIYKIVEKVEQQKLLKYRCKFDYTIGTMIELPRAALQA CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH YELAQEVDFFCFGTNDLTQTTYGISRDDSTSFINQYIENDIFTADPFTTLDCEAVGELIQ HHHHHHCCEEEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH IAIERGRTAKKHLKIGICGEHAADSNSVEFFHKVKVDSISCSPYKIPIARLAAAQAALKN HHHHCCCCCHHHEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCC N C >Mature Secondary Structure TKWIYRFSSTSANLPHINSVDQSCNIMKDNLQSLLGNKGVTLAQMFSQKLPIPHGFIIS CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEH TKLYHYYQQNNDSLPSDFISDLKSSILDLEHQTGKNFGDYNNPLLVAVRSSAAVSMPGIM HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHH NTILNLGINDIIVEGLSTVTGNRIFALDTYMRFIQTYGQVVMGVSPAEFELALNQFKTLN HHHHHCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH NITSQEQLTSEHLHNLITIFKQIIHKETKQKFPQDVNIQLHQAIQAVLKSWMNHHAITYR HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEE KLNNISGNIGTAIIVQTMVFGNMGSDSATGVVFTRNPLTGDNKLYGEFLINAQGDNVVSG HHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEC ASIPNSILSDNKDQKCTLKYAMHKMYEELLQHCKQLEQHYCNIQDIEFTIEKQKLYILQT CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEE RSAKCTALATIKALVDMVASGLITKKEAIAKINPMSLNQLLHSYIDESENYKVITQGLPS CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCC TPGAVTGVIALSVAAAEKLSNQHHKVIFICSNISPEDIKAMHISSGILTSGGNTTSHAAI CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCEEECCCCCHHHHHH LSRALGKPHICAAKDVIIDQQNGLIKIGDISLYQGSKITIDGNSGKVFVGDVRLLQPEFS HHHHCCCCCCEECCCEEEECCCCEEEEECEEEECCCEEEEECCCCEEEEECEEEECCCHH KECQLFMEWADEIKTVEVKANADTSDDVKLALRLGATSIGLCRTEHMLLEDNKISLVQET HHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCHHCCCCEEECCCCHHHHHHH IIADNDQCRLNALKRLFLLHKADFKELFAATMQIPINIRLLDAPLHEFLPTTFTTAHNRI HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCHHHHCCCHHHHHHHHH IDNLNISQETFNARINTLKEVNPMLGHRGCRIGISFPEIYEMQVRAIFEAAAEILLELKV HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHC MPKIEVTIPLISHKKELQLLKRIIYKIVEKVEQQKLLKYRCKFDYTIGTMIELPRAALQA CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH YELAQEVDFFCFGTNDLTQTTYGISRDDSTSFINQYIENDIFTADPFTTLDCEAVGELIQ HHHHHHCCEEEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH IAIERGRTAKKHLKIGICGEHAADSNSVEFFHKVKVDSISCSPYKIPIARLAAAQAALKN HHHHCCCCCHHHEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCC N C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9823893 [H]