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The map label for this gene is czcR [H]

Identifier: 189183277

GI number: 189183277

Start: 377560

End: 378297

Strand: Reverse

Name: czcR [H]

Synonym: OTT_0370

Alternate gene names: 189183277

Gene position: 378297-377560 (Counterclockwise)

Preceding gene: 189183282

Following gene: 189183276

Centisome position: 18.83

GC content: 30.08

Gene sequence:

>738_bases
ATGCGTGTTCTACTAATTGAAGATGATCCAGCACAAGCATCATCTATTGAGCTATCTTTAGCTAATGAAGGTATCATTGC
TGATAAAGCTCATTTAGGTAAAGATGGAATTGAGATCTCAAAATTATATGATTATTCTCTTATCATATTAGATTTAATGT
TACCAGATATAAGTGGATATGAGGTTCTACTAAGCTTAAGATCTCAAAAAATCCAAACTCCTGTTTTGATTTTATCTGGT
TTATCAACTATTGATAATAAAATTAAGGGCTTATCATTTGGTGCAGATGATTATATAACTAAACCTTTTGATTCTGATGA
GCTATCTGCTAGAGTAAAAGCTATTATACGTCGATCAAAAGGGCATTCAGAGGCGGTAATTAGAGTTGGACATTTATCAA
TAAATCTTGATACAAGGTCTGTTTCTATGTATAACAAGGATAAGCAAAAGAATATGCCTATACATTTAACTAATAAAGAA
TATAAAATCCTTGAGCTTTTAGCGATTAAGAAAGGTACTGTTTTAACTAAAGAAATGTTCCTAAGTCATCTTTATAGTGG
TATAGATGAACCAGAAATTAAAATTATTGATGTATTTATATGCAAGCTGCGTCGAAAACTTGAAAAAGCGTCTAATGGTA
TTAACTTCATTGAGACAGTATGGGGTAGAGGATATATATTTGCAGAATTTAAGTCTAACGATAATAATTATAGCTTAAAT
AATGTTGAAGAAGAATAA

Upstream 100 bases:

>100_bases
CTTATAAAGAAATAACTTGATTTTATGATAAGTTCATGAGATTATACGTTAAAATTAATCTTTAGAATTATGTTACAATA
ACGCTCATGAGGCAAAATAA

Downstream 100 bases:

>100_bases
GTTAATATATATTATTTTTAAATAATATATATTTGTTCTCACCTATAATCAAAAATGTTCTTAACAAAAAAATTATTACT
ACCTATTTTTAGTTCAATAA

Product: transcriptional activator protein CzcR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRVLLIEDDPAQASSIELSLANEGIIADKAHLGKDGIEISKLYDYSLIILDLMLPDISGYEVLLSLRSQKIQTPVLILSG
LSTIDNKIKGLSFGADDYITKPFDSDELSARVKAIIRRSKGHSEAVIRVGHLSINLDTRSVSMYNKDKQKNMPIHLTNKE
YKILELLAIKKGTVLTKEMFLSHLYSGIDEPEIKIIDVFICKLRRKLEKASNGINFIETVWGRGYIFAEFKSNDNNYSLN
NVEEE

Sequences:

>Translated_245_residues
MRVLLIEDDPAQASSIELSLANEGIIADKAHLGKDGIEISKLYDYSLIILDLMLPDISGYEVLLSLRSQKIQTPVLILSG
LSTIDNKIKGLSFGADDYITKPFDSDELSARVKAIIRRSKGHSEAVIRVGHLSINLDTRSVSMYNKDKQKNMPIHLTNKE
YKILELLAIKKGTVLTKEMFLSHLYSGIDEPEIKIIDVFICKLRRKLEKASNGINFIETVWGRGYIFAEFKSNDNNYSLN
NVEEE
>Mature_245_residues
MRVLLIEDDPAQASSIELSLANEGIIADKAHLGKDGIEISKLYDYSLIILDLMLPDISGYEVLLSLRSQKIQTPVLILSG
LSTIDNKIKGLSFGADDYITKPFDSDELSARVKAIIRRSKGHSEAVIRVGHLSINLDTRSVSMYNKDKQKNMPIHLTNKE
YKILELLAIKKGTVLTKEMFLSHLYSGIDEPEIKIIDVFICKLRRKLEKASNGINFIETVWGRGYIFAEFKSNDNNYSLN
NVEEE

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=35.1931330472103, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.2105263157895, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=33.7662337662338, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=34.4978165938865, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.5991189427313, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=31.2236286919831, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=30.6666666666667, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=31.6239316239316, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=29.9559471365639, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.8035714285714, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=27.7777777777778, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693140, Length=243, Percent_Identity=27.5720164609054, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27619; Mature: 27619

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDPAQASSIELSLANEGIIADKAHLGKDGIEISKLYDYSLIILDLMLPDISGY
CEEEEEECCCCCCCEEEEEECCCCEEECHHHCCCCCCEEEHHHHHHHEEEEHHCCCCCCH
EVLLSLRSQKIQTPVLILSGLSTIDNKIKGLSFGADDYITKPFDSDELSARVKAIIRRSK
HHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GHSEAVIRVGHLSINLDTRSVSMYNKDKQKNMPIHLTNKEYKILELLAIKKGTVLTKEMF
CCCCEEEEEEEEEEEEECCEEEECCCHHHCCCCEEECCCCEEEEEEEECCCCCCHHHHHH
LSHLYSGIDEPEIKIIDVFICKLRRKLEKASNGINFIETVWGRGYIFAEFKSNDNNYSLN
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEECCCCCEECC
NVEEE
CCCCC
>Mature Secondary Structure
MRVLLIEDDPAQASSIELSLANEGIIADKAHLGKDGIEISKLYDYSLIILDLMLPDISGY
CEEEEEECCCCCCCEEEEEECCCCEEECHHHCCCCCCEEEHHHHHHHEEEEHHCCCCCCH
EVLLSLRSQKIQTPVLILSGLSTIDNKIKGLSFGADDYITKPFDSDELSARVKAIIRRSK
HHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GHSEAVIRVGHLSINLDTRSVSMYNKDKQKNMPIHLTNKEYKILELLAIKKGTVLTKEMF
CCCCEEEEEEEEEEEEECCEEEECCCHHHCCCCEEECCCCEEEEEEEECCCCCCHHHHHH
LSHLYSGIDEPEIKIIDVFICKLRRKLEKASNGINFIETVWGRGYIFAEFKSNDNNYSLN
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEECCCCCEECC
NVEEE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA