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The map label for this gene is fabZ [H]

Identifier: 189182979

GI number: 189182979

Start: 75699

End: 76184

Strand: Reverse

Name: fabZ [H]

Synonym: OTT_0072

Alternate gene names: 189182979

Gene position: 76184-75699 (Counterclockwise)

Preceding gene: 189182981

Following gene: 189182978

Centisome position: 3.79

GC content: 30.86

Gene sequence:

>486_bases
ATGTCTCAACAAAAACAACTATCAGAAAATAACTCTGTATTGAGCACACAAGACATCATTAGGATTATACCACATAGATA
TCCTTTTTTAATGATAGATAAAGTTATCAAACTAGAACCTGGTCAAGAAATCATAGGAATTAAGAACGTTACAGCTAATG
AGCCACAGTTCGCAGGTCATTTCCCTAACAATCCAGTTATGCCAGGAGTTCTAACCATTGAATCAATGGCTCAGTTATCT
GCTATTTTAGTAGCAAAAACTATTAAGTTTGATACTAACGGCAAAATTTTCTACTTAATAACCATTGAAAAAGTAAAATT
CAGGAAAATAATTACTAGTGGAGATACCATGGTTATTACATCTAAAATTTCTCAAGCTTATAATAAGCATATATGGAAAT
TTAATGCAGAAGTTAAAATTGATGGTACAAATAACCTAGCTGCTGAAGGGACATTTACTGCAAGTTTAAAAGATTTATTA
AACTAA

Upstream 100 bases:

>100_bases
TTTCATATTATTATAAAGACTCAAATTATTAAAGCCATTACTATTCTAGTAAATATAGTTATTAAACAATCTTAAAAAAT
AATGTAGCAAAGATAAGATA

Downstream 100 bases:

>100_bases
TTCTAAAAAAATTAACTTATGATTCAAGTAATTTCGGGAAAATTTAAAGGACAAAAAATTCCAGTTATTAAAAATAATAA
TTATCGCCCATCCACAGCCA

Product: (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSQQKQLSENNSVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQEIIGIKNVTANEPQFAGHFPNNPVMPGVLTIESMAQLS
AILVAKTIKFDTNGKIFYLITIEKVKFRKIITSGDTMVITSKISQAYNKHIWKFNAEVKIDGTNNLAAEGTFTASLKDLL
N

Sequences:

>Translated_161_residues
MSQQKQLSENNSVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQEIIGIKNVTANEPQFAGHFPNNPVMPGVLTIESMAQLS
AILVAKTIKFDTNGKIFYLITIEKVKFRKIITSGDTMVITSKISQAYNKHIWKFNAEVKIDGTNNLAAEGTFTASLKDLL
N
>Mature_160_residues
SQQKQLSENNSVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQEIIGIKNVTANEPQFAGHFPNNPVMPGVLTIESMAQLSA
ILVAKTIKFDTNGKIFYLITIEKVKFRKIITSGDTMVITSKISQAYNKHIWKFNAEVKIDGTNNLAAEGTFTASLKDLLN

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=33.8235294117647, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18005; Mature: 17874

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQKQLSENNSVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQEIIGIKNVTANEPQFAGH
CCCCHHCCCCCCEECHHHHHHHHCCCCCCEEECCEEEECCCCEEEEEECCCCCCCCCCCC
FPNNPVMPGVLTIESMAQLSAILVAKTIKFDTNGKIFYLITIEKVKFRKIITSGDTMVIT
CCCCCCCCCEEEHHHHHHHHHHHHHEEEEECCCCCEEEEEEECCEEEEEEEECCCEEEEE
SKISQAYNKHIWKFNAEVKIDGTNNLAAEGTFTASLKDLLN
HHHHHHHHCCEEEECCEEEECCCCCEECCCEEHHHHHHHCC
>Mature Secondary Structure 
SQQKQLSENNSVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQEIIGIKNVTANEPQFAGH
CCCHHCCCCCCEECHHHHHHHHCCCCCCEEECCEEEECCCCEEEEEECCCCCCCCCCCC
FPNNPVMPGVLTIESMAQLSAILVAKTIKFDTNGKIFYLITIEKVKFRKIITSGDTMVIT
CCCCCCCCCEEEHHHHHHHHHHHHHEEEEECCCCCEEEEEEECCEEEEEEEECCCEEEEE
SKISQAYNKHIWKFNAEVKIDGTNNLAAEGTFTASLKDLLN
HHHHHHHHCCEEEECCEEEECCCCCEECCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA