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The map label for this gene is lacA [C]

Identifier: 189182951

GI number: 189182951

Start: 51565

End: 52014

Strand: Reverse

Name: lacA [C]

Synonym: OTT_0044

Alternate gene names: 189182951

Gene position: 52014-51565 (Counterclockwise)

Preceding gene: 189182952

Following gene: 189182948

Centisome position: 2.59

GC content: 31.33

Gene sequence:

>450_bases
ATGGTTTCATCTAATATTATTGCTATAGCATCTGATCAAAAAGAGTACGAGTTAAAAACAAAAATTTGTCAACATTTATC
TGAGCAAGAACGTTTTATTAGTTTTTCAGTCCTTGATCTAGGAGGTAATAATAATCAGCAGGTTGATTATCCAGATATTG
CCAACTTATTATGTGATACTATAATTAATAATCGAGCTAAATATGGTATTTTAATTTGCACAACAGGTATTGGCATGAGT
ATAGCTGCAAATAGGCATTCTGATATTAGAGCCGCTTTATGCTTTAATGAATATATGGCAGAGCAATCGCGTTTGCACAA
TAATGCTAATATCTTAATTATAGGAGCCAAGGTTTCTAATTTTAGGTCTGTTATTAATATGATTTCAAAATTTATAACTA
CAAAATTTGAAGGTGGCCGCCACTTGACTAGACTTGAAAAGCTTAGATAG

Upstream 100 bases:

>100_bases
AATGCTTTACCAAAAAATTCTTATTTTTTCATAATTTTATTATTGATAATACAAAATATAATATTAAAATGAAGGTGTTT
TTATTGCCAAAATTTTTTTT

Downstream 100 bases:

>100_bases
AAATGGATTCACTTATTACATATGGTAGTAGACACAAGAGTCATAACTTTACATATCACTAGTTACGCTAATTTAGGATA
AGAAAAAATATGAAAAGTAG

Product: ribose-5-phosphate isomerase

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MVSSNIIAIASDQKEYELKTKICQHLSEQERFISFSVLDLGGNNNQQVDYPDIANLLCDTIINNRAKYGILICTTGIGMS
IAANRHSDIRAALCFNEYMAEQSRLHNNANILIIGAKVSNFRSVINMISKFITTKFEGGRHLTRLEKLR

Sequences:

>Translated_149_residues
MVSSNIIAIASDQKEYELKTKICQHLSEQERFISFSVLDLGGNNNQQVDYPDIANLLCDTIINNRAKYGILICTTGIGMS
IAANRHSDIRAALCFNEYMAEQSRLHNNANILIIGAKVSNFRSVINMISKFITTKFEGGRHLTRLEKLR
>Mature_149_residues
MVSSNIIAIASDQKEYELKTKICQHLSEQERFISFSVLDLGGNNNQQVDYPDIANLLCDTIINNRAKYGILICTTGIGMS
IAANRHSDIRAALCFNEYMAEQSRLHNNANILIIGAKVSNFRSVINMISKFITTKFEGGRHLTRLEKLR

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=142, Percent_Identity=35.2112676056338, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 16766; Mature: 16766

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSNIIAIASDQKEYELKTKICQHLSEQERFISFSVLDLGGNNNQQVDYPDIANLLCDT
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHH
IINNRAKYGILICTTGIGMSIAANRHSDIRAALCFNEYMAEQSRLHNNANILIIGAKVSN
HHCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHH
FRSVINMISKFITTKFEGGRHLTRLEKLR
HHHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MVSSNIIAIASDQKEYELKTKICQHLSEQERFISFSVLDLGGNNNQQVDYPDIANLLCDT
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHH
IINNRAKYGILICTTGIGMSIAANRHSDIRAALCFNEYMAEQSRLHNNANILIIGAKVSN
HHCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHH
FRSVINMISKFITTKFEGGRHLTRLEKLR
HHHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA