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The map label for this gene is trxB

Identifier: 189026038

GI number: 189026038

Start: 884135

End: 885058

Strand: Direct

Name: trxB

Synonym: TPASS_0814

Alternate gene names: 189026038

Gene position: 884135-885058 (Clockwise)

Preceding gene: 189026035

Following gene: 189026039

Centisome position: 77.59

GC content: 53.14

Gene sequence:

>924_bases
ATGGAGACAGATTACGACGTTATCATCGTAGGCGCTGGGGCCGCGGGACTGTCCGCAGCGCAGTACGCATGTCGCGCCAA
TCTCAGGACCCTTGTGATTGAGAGCAAGGCACACGGTGGTCAAGCATTGCTTATTGATTCGTTGGAAAACTATCCGGGTT
ATGCAACTCCTATCAGTGGCTTCGAGTACGCGGAAAACATGAAAAAGCAGGCAGTTGCCTTTGGGGCTCAGATTGCTTAC
GAAGAAGTTACCACTATCGGTAAGCGCGATAGCGTTTTCCACATTACCACGGGTACGGGAGCATATACGGCGATGTCTGT
TATTCTTGCCACCGGTGCAGAGCATCGCAAGATGGGCATCCCGGGGGAGAGTGAGTTTTTAGGCCGTGGCGTTTCCTATT
GTGCCACCTGCGATGGACCCTTCTTTAGAAACAAGCACGTGGTGGTCATTGGTGGGGGTGACGCTGCGTGTGATGAATCG
CTAGTACTGTCTCGCCTCACCGATCGGGTGACGATGATTCACCGCAGGGACACTCTGCGTGCACAGAAGGCCATTGCAGA
GCGCACACTTAAAAATCCACATATTGCCGTTCAATGGAACACTACGCTTGAAGCGGTACGTGGTGAAACGAAAGTTTCCT
CCGTTCTGCTTAAGGATGTTAAGACGGGAGAAACGCGAGAGCTCGCGTGTGATGCTGTTTTCTTCTTCATCGGTATGGTT
CCCATCACCGGTCTTTTGCCCGACGCAGAAAAGGATTCCACCGGTTATATCGTCACCGACGACGAGATGCGTACCTCTGT
AGAGGGGATTTTCGCTGCGGGGGATGTGCGCGCTAAGTCTTTCCGGCAGGTTATTACTGCTACTTCGGATGGTGCCCTTG
CCGCGCACGCCGCCGCGAGTTACATCGACACACTCCAAAACTAA

Upstream 100 bases:

>100_bases
ACGTATCTTCTCCTGAATTCAATCATATATTTTTTACCGGCATACATAGGGCACCTAAAAAAGCGTTGACTAATCAGTTA
CGCGTGCATACACTCTCGGC

Downstream 100 bases:

>100_bases
AACTGCGCGTCTTTGCACTTCGGGTGTGCGTTTTTTATCCTTCGAGGGGAGGGTACTGTTCTCTCTCCCCATCCCCAACT
CTTTCTGAGGAAGCTTTGGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
METDYDVIIVGAGAAGLSAAQYACRANLRTLVIESKAHGGQALLIDSLENYPGYATPISGFEYAENMKKQAVAFGAQIAY
EEVTTIGKRDSVFHITTGTGAYTAMSVILATGAEHRKMGIPGESEFLGRGVSYCATCDGPFFRNKHVVVIGGGDAACDES
LVLSRLTDRVTMIHRRDTLRAQKAIAERTLKNPHIAVQWNTTLEAVRGETKVSSVLLKDVKTGETRELACDAVFFFIGMV
PITGLLPDAEKDSTGYIVTDDEMRTSVEGIFAAGDVRAKSFRQVITATSDGALAAHAAASYIDTLQN

Sequences:

>Translated_307_residues
METDYDVIIVGAGAAGLSAAQYACRANLRTLVIESKAHGGQALLIDSLENYPGYATPISGFEYAENMKKQAVAFGAQIAY
EEVTTIGKRDSVFHITTGTGAYTAMSVILATGAEHRKMGIPGESEFLGRGVSYCATCDGPFFRNKHVVVIGGGDAACDES
LVLSRLTDRVTMIHRRDTLRAQKAIAERTLKNPHIAVQWNTTLEAVRGETKVSSVLLKDVKTGETRELACDAVFFFIGMV
PITGLLPDAEKDSTGYIVTDDEMRTSVEGIFAAGDVRAKSFRQVITATSDGALAAHAAASYIDTLQN
>Mature_307_residues
METDYDVIIVGAGAAGLSAAQYACRANLRTLVIESKAHGGQALLIDSLENYPGYATPISGFEYAENMKKQAVAFGAQIAY
EEVTTIGKRDSVFHITTGTGAYTAMSVILATGAEHRKMGIPGESEFLGRGVSYCATCDGPFFRNKHVVVIGGGDAACDES
LVLSRLTDRVTMIHRRDTLRAQKAIAERTLKNPHIAVQWNTTLEAVRGETKVSSVLLKDVKTGETRELACDAVFFFIGMV
PITGLLPDAEKDSTGYIVTDDEMRTSVEGIFAAGDVRAKSFRQVITATSDGALAAHAAASYIDTLQN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=38.1877022653722, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=33.4415584415584, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=35.9872611464968, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=36.2179487179487, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_TREPA (O83790)

Other databases:

- EMBL:   AE000520
- PIR:   C71278
- RefSeq:   NP_219250.1
- ProteinModelPortal:   O83790
- SMR:   O83790
- IntAct:   O83790
- GeneID:   2610892
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0814
- NMPDR:   fig|243276.1.peg.809
- TIGR:   TP_0814
- HOGENOM:   HBG669726
- OMA:   ASEVHIF
- ProtClustDB:   CLSK2300308
- BioCyc:   TPAL243276:TP_0814-MONOMER
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 32869; Mature: 32869

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METDYDVIIVGAGAAGLSAAQYACRANLRTLVIESKAHGGQALLIDSLENYPGYATPISG
CCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHCCCCCCCCCCC
FEYAENMKKQAVAFGAQIAYEEVTTIGKRDSVFHITTGTGAYTAMSVILATGAEHRKMGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCC
PGESEFLGRGVSYCATCDGPFFRNKHVVVIGGGDAACDESLVLSRLTDRVTMIHRRDTLR
CCCHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQKAIAERTLKNPHIAVQWNTTLEAVRGETKVSSVLLKDVKTGETRELACDAVFFFIGMV
HHHHHHHHHCCCCEEEEEECCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
PITGLLPDAEKDSTGYIVTDDEMRTSVEGIFAAGDVRAKSFRQVITATSDGALAAHAAAS
HHHCCCCCCCCCCCCEEEECHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCHHHHHHHH
YIDTLQN
HHHHHCC
>Mature Secondary Structure
METDYDVIIVGAGAAGLSAAQYACRANLRTLVIESKAHGGQALLIDSLENYPGYATPISG
CCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHCCCCCCCCCCC
FEYAENMKKQAVAFGAQIAYEEVTTIGKRDSVFHITTGTGAYTAMSVILATGAEHRKMGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCC
PGESEFLGRGVSYCATCDGPFFRNKHVVVIGGGDAACDESLVLSRLTDRVTMIHRRDTLR
CCCHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQKAIAERTLKNPHIAVQWNTTLEAVRGETKVSSVLLKDVKTGETRELACDAVFFFIGMV
HHHHHHHHHCCCCEEEEEECCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
PITGLLPDAEKDSTGYIVTDDEMRTSVEGIFAAGDVRAKSFRQVITATSDGALAAHAAAS
HHHCCCCCCCCCCCCEEEECHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCHHHHHHHH
YIDTLQN
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876