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The map label for this gene is recG

Identifier: 189025912

GI number: 189025912

Start: 754269

End: 756329

Strand: Reverse

Name: recG

Synonym: TPASS_0687

Alternate gene names: 189025912

Gene position: 756329-754269 (Counterclockwise)

Preceding gene: 189025913

Following gene: 189025907

Centisome position: 66.38

GC content: 42.5

Gene sequence:

>2061_bases
ATGCTCATTGGAGAAATAAAAGAGCCAGTTTCTGTACTGAAGGGAACAGGGAAAGTTGTTCTTGCGCAGTTGGAAAGGCT
AAACATTAGCACTATTGGAGATATCCTTTCGTACTGGCCTCGTTTGTGGGAAGATAGAACGCAAGAACAGATGTTTTCCC
AATGGACGCTGGCGCATAGATTGCAAGTACGAGTTAGTGTCACTGCACATTGCTGGTTTGGATTTGGCAAGAGCAAGACT
CTCAAGCTTGTGGTACAGGATGGCCAAGGATGCGTCGCTGAATTGTTATGTTTTCGCCGTAATTTTTTGCATTTTATGTT
TCCTGTTGGAAGTGAAGCAGTCGTGTATGGAAGTTTTTATGAAAAGGATGGGTTGCTGGAAAGTAGTTCATTTGATATCG
AAAAAATCGATTGTATTGAAAAAAAGATTTTGCCTGTCTATCCCTTAACCAAAGGGTTAAAACAAATGAAATTAAGAATG
CTCATTTGTGCAGCAATGGATCAATGGATTGGCACGGTTGATTCTGAATTGCCCAAACCTATTCTTGAGAAATATCATCT
ACTCACAAAACGAGACGTATTGCTTAGTATGCATACCCCAAGAACGCTGGATGATGTTGCGAAGGGAAAACATTCTTTGA
TATTTGAAGAATTTTTTTCTCTTCAAATGACTATCGGTATGCGCTCTTTACAGAAGCGGGGGAGATTGCCTCTTACACAG
GGAGAATCTGATCAGCAGTCGGCTATTCCGTCAGTTGTTTCTGAATTATCTTTGTTACAGAAGAAACTTCACCGGTGTTT
GCCATTTGAGTTGACAGTGGATCAGAAAAGAGTAATTACAGAAATTACGCAGGATCTTGAAAGAGAAGAACCGATGGCAC
GGCTAATTCAGGGAGACGTTGGATCAGGAAAAACGTTAGTGGCGTTTTTTTCTTGTTTAAAAATTATTGAACAAGGTGGA
CAGGTCGCACTGCTTGCTCCAACTGAATTACTTGCACGCCAGCATGCTGACACTGCAGCTCGATTACTTGCTCCTATTGG
GATTCGACTTGCATTCCTGACAGGTAATGTGAAAAGTGAAGGAAGGGCGTACTTGCTCGAAGCTCTTGTTGCAGGAGAAA
TCAATTTAGTTGTAGGAACACATGCGCTGTTTTCAAAGAGCGTAAGATACCATGATCTGAGGTTGGTTATCATTGACGAA
CAGCATCGTTTTGGAGTGTTACAGCGTTCGGCCTTGATTCAGAAAGGAAGGGAAGGGAACCCTCAGGGAAAGACTCCACA
CATTATTATGATGAGCGCAACTCCAATTCCACGTACGCTTGCACTTTCTGTATTTGGTGATTTAGATATTTCAATAATTA
AATCTATGCCTGGTGGAAGAAAACCAGTGATTACGTATATTGCAAGAAAGACGAAAGCAGAAAAGGTGTATGAGTTTGTG
GGAAATGAAATAGAAAAAGGTAGGCAGGCATATTTTATTTATCCACGTATTCATGACATAGGATTAACCGATTTAAAATC
GGTGCAATGTATGTATATGTATCTAAAAAATTATTTTGCACGATATGCTGTTGCGATGATTCACTCAAAAATGACTGAGG
AAGAGCAGCAGCGTATCATGAAGTATTTCAGCGAAGGTACCGTCCATATCTTGGTTGCTACAAGCGTTGTTGAAGTGGGA
GTGGATGTACCAAATGCGAATTGTATCGTTATAGAGCACGCGGAGCGTTTTGGCCTCTCTGCACTACATCAACTGCGTGG
TCGGGTTGGTCGGGGTGATGTGCAGTCGTATTGTTTCTTAATGCATGGGGACGAAATGACTGAGTGTGCGAAACGCAGGC
TGAAAATTATGGGAAGTACTGCGGATGGATTTGTTATCGCCGAAGAGGATCTGAAGTTACGAGGACCAGGGGATGTGGGA
GATACCAAGAACTTTGAGCAATCTGGGTACAGTGGATTTCGGGTTGCGGATCCAGTAAGAGATTACCCTATCCTCCAAGT
TGCGCGCGAAGCGGCGTTCGAACTACTGAGAAAAGAAAAGGGCTCATCTGAAGCACGGTAG

Upstream 100 bases:

>100_bases
ATTACTGTTCAGTTGCATTCCTCAGTTGAGCAACTCCCAGAGTAATTTCGGTGAATGATGTTCTTGCGTTACCATTACGT
ATGCTCGCACACTGCCTGAA

Downstream 100 bases:

>100_bases
AGCTCGGACAGCGGAGGCCTTCTTGTCAGCCCACACCCTGAGTTAGCCAAAGAGGGAACAATGGCCCAGAAAGGCGCCCG
GCTTATTCGTATTGTGAACG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MLIGEIKEPVSVLKGTGKVVLAQLERLNISTIGDILSYWPRLWEDRTQEQMFSQWTLAHRLQVRVSVTAHCWFGFGKSKT
LKLVVQDGQGCVAELLCFRRNFLHFMFPVGSEAVVYGSFYEKDGLLESSSFDIEKIDCIEKKILPVYPLTKGLKQMKLRM
LICAAMDQWIGTVDSELPKPILEKYHLLTKRDVLLSMHTPRTLDDVAKGKHSLIFEEFFSLQMTIGMRSLQKRGRLPLTQ
GESDQQSAIPSVVSELSLLQKKLHRCLPFELTVDQKRVITEITQDLEREEPMARLIQGDVGSGKTLVAFFSCLKIIEQGG
QVALLAPTELLARQHADTAARLLAPIGIRLAFLTGNVKSEGRAYLLEALVAGEINLVVGTHALFSKSVRYHDLRLVIIDE
QHRFGVLQRSALIQKGREGNPQGKTPHIIMMSATPIPRTLALSVFGDLDISIIKSMPGGRKPVITYIARKTKAEKVYEFV
GNEIEKGRQAYFIYPRIHDIGLTDLKSVQCMYMYLKNYFARYAVAMIHSKMTEEEQQRIMKYFSEGTVHILVATSVVEVG
VDVPNANCIVIEHAERFGLSALHQLRGRVGRGDVQSYCFLMHGDEMTECAKRRLKIMGSTADGFVIAEEDLKLRGPGDVG
DTKNFEQSGYSGFRVADPVRDYPILQVAREAAFELLRKEKGSSEAR

Sequences:

>Translated_686_residues
MLIGEIKEPVSVLKGTGKVVLAQLERLNISTIGDILSYWPRLWEDRTQEQMFSQWTLAHRLQVRVSVTAHCWFGFGKSKT
LKLVVQDGQGCVAELLCFRRNFLHFMFPVGSEAVVYGSFYEKDGLLESSSFDIEKIDCIEKKILPVYPLTKGLKQMKLRM
LICAAMDQWIGTVDSELPKPILEKYHLLTKRDVLLSMHTPRTLDDVAKGKHSLIFEEFFSLQMTIGMRSLQKRGRLPLTQ
GESDQQSAIPSVVSELSLLQKKLHRCLPFELTVDQKRVITEITQDLEREEPMARLIQGDVGSGKTLVAFFSCLKIIEQGG
QVALLAPTELLARQHADTAARLLAPIGIRLAFLTGNVKSEGRAYLLEALVAGEINLVVGTHALFSKSVRYHDLRLVIIDE
QHRFGVLQRSALIQKGREGNPQGKTPHIIMMSATPIPRTLALSVFGDLDISIIKSMPGGRKPVITYIARKTKAEKVYEFV
GNEIEKGRQAYFIYPRIHDIGLTDLKSVQCMYMYLKNYFARYAVAMIHSKMTEEEQQRIMKYFSEGTVHILVATSVVEVG
VDVPNANCIVIEHAERFGLSALHQLRGRVGRGDVQSYCFLMHGDEMTECAKRRLKIMGSTADGFVIAEEDLKLRGPGDVG
DTKNFEQSGYSGFRVADPVRDYPILQVAREAAFELLRKEKGSSEAR
>Mature_686_residues
MLIGEIKEPVSVLKGTGKVVLAQLERLNISTIGDILSYWPRLWEDRTQEQMFSQWTLAHRLQVRVSVTAHCWFGFGKSKT
LKLVVQDGQGCVAELLCFRRNFLHFMFPVGSEAVVYGSFYEKDGLLESSSFDIEKIDCIEKKILPVYPLTKGLKQMKLRM
LICAAMDQWIGTVDSELPKPILEKYHLLTKRDVLLSMHTPRTLDDVAKGKHSLIFEEFFSLQMTIGMRSLQKRGRLPLTQ
GESDQQSAIPSVVSELSLLQKKLHRCLPFELTVDQKRVITEITQDLEREEPMARLIQGDVGSGKTLVAFFSCLKIIEQGG
QVALLAPTELLARQHADTAARLLAPIGIRLAFLTGNVKSEGRAYLLEALVAGEINLVVGTHALFSKSVRYHDLRLVIIDE
QHRFGVLQRSALIQKGREGNPQGKTPHIIMMSATPIPRTLALSVFGDLDISIIKSMPGGRKPVITYIARKTKAEKVYEFV
GNEIEKGRQAYFIYPRIHDIGLTDLKSVQCMYMYLKNYFARYAVAMIHSKMTEEEQQRIMKYFSEGTVHILVATSVVEVG
VDVPNANCIVIEHAERFGLSALHQLRGRVGRGDVQSYCFLMHGDEMTECAKRRLKIMGSTADGFVIAEEDLKLRGPGDVG
DTKNFEQSGYSGFRVADPVRDYPILQVAREAAFELLRKEKGSSEAR

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Escherichia coli, GI2367254, Length=674, Percent_Identity=37.0919881305638, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1787357, Length=432, Percent_Identity=35.1851851851852, Blast_Score=241, Evalue=9e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECG_TREPA (P96130)

Other databases:

- EMBL:   U70661
- EMBL:   AE000520
- PIR:   D71292
- RefSeq:   NP_219124.1
- ProteinModelPortal:   P96130
- SMR:   P96130
- IntAct:   P96130
- GeneID:   2611432
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0687
- NMPDR:   fig|243276.1.peg.683
- TIGR:   TP_0687
- HOGENOM:   HBG747311
- OMA:   SKYICFN
- ProtClustDB:   PRK10917
- BioCyc:   TPAL243276:TP_0687-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- SMART:   SM00487
- SMART:   SM00490
- TIGRFAMs:   TIGR00643

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; SSF50249 Nucleic_acid_OB

EC number: =3.6.4.12

Molecular weight: Translated: 77198; Mature: 77198

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGEIKEPVSVLKGTGKVVLAQLERLNISTIGDILSYWPRLWEDRTQEQMFSQWTLAHR
CCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LQVRVSVTAHCWFGFGKSKTLKLVVQDGQGCVAELLCFRRNFLHFMFPVGSEAVVYGSFY
EEEEEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCEEEEECCC
EKDGLLESSSFDIEKIDCIEKKILPVYPLTKGLKQMKLRMLICAAMDQWIGTVDSELPKP
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILEKYHLLTKRDVLLSMHTPRTLDDVAKGKHSLIFEEFFSLQMTIGMRSLQKRGRLPLTQ
HHHHHHHHHHHHHEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GESDQQSAIPSVVSELSLLQKKLHRCLPFELTVDQKRVITEITQDLEREEPMARLIQGDV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHCCCC
GSGKTLVAFFSCLKIIEQGGQVALLAPTELLARQHADTAARLLAPIGIRLAFLTGNVKSE
CCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
GRAYLLEALVAGEINLVVGTHALFSKSVRYHDLRLVIIDEQHRFGVLQRSALIQKGREGN
CHHHHHHHHHHCCEEEEEECHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCC
PQGKTPHIIMMSATPIPRTLALSVFGDLDISIIKSMPGGRKPVITYIARKTKAEKVYEFV
CCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
GNEIEKGRQAYFIYPRIHDIGLTDLKSVQCMYMYLKNYFARYAVAMIHSKMTEEEQQRIM
HHHHHCCCEEEEEECEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KYFSEGTVHILVATSVVEVGVDVPNANCIVIEHAERFGLSALHQLRGRVGRGDVQSYCFL
HHHCCCCEEEEEEEHHHHHCCCCCCCCEEEEECHHHCCHHHHHHHHCCCCCCCHHHEEEE
MHGDEMTECAKRRLKIMGSTADGFVIAEEDLKLRGPGDVGDTKNFEQSGYSGFRVADPVR
EECCHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCCCCCCCHHCCCCCCEECCCCC
DYPILQVAREAAFELLRKEKGSSEAR
CCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLIGEIKEPVSVLKGTGKVVLAQLERLNISTIGDILSYWPRLWEDRTQEQMFSQWTLAHR
CCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LQVRVSVTAHCWFGFGKSKTLKLVVQDGQGCVAELLCFRRNFLHFMFPVGSEAVVYGSFY
EEEEEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCEEEEECCC
EKDGLLESSSFDIEKIDCIEKKILPVYPLTKGLKQMKLRMLICAAMDQWIGTVDSELPKP
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILEKYHLLTKRDVLLSMHTPRTLDDVAKGKHSLIFEEFFSLQMTIGMRSLQKRGRLPLTQ
HHHHHHHHHHHHHEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GESDQQSAIPSVVSELSLLQKKLHRCLPFELTVDQKRVITEITQDLEREEPMARLIQGDV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHCCCC
GSGKTLVAFFSCLKIIEQGGQVALLAPTELLARQHADTAARLLAPIGIRLAFLTGNVKSE
CCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
GRAYLLEALVAGEINLVVGTHALFSKSVRYHDLRLVIIDEQHRFGVLQRSALIQKGREGN
CHHHHHHHHHHCCEEEEEECHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCC
PQGKTPHIIMMSATPIPRTLALSVFGDLDISIIKSMPGGRKPVITYIARKTKAEKVYEFV
CCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
GNEIEKGRQAYFIYPRIHDIGLTDLKSVQCMYMYLKNYFARYAVAMIHSKMTEEEQQRIM
HHHHHCCCEEEEEECEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KYFSEGTVHILVATSVVEVGVDVPNANCIVIEHAERFGLSALHQLRGRVGRGDVQSYCFL
HHHCCCCEEEEEEEHHHHHCCCCCCCCEEEEECHHHCCHHHHHHHHCCCCCCCHHHEEEE
MHGDEMTECAKRRLKIMGSTADGFVIAEEDLKLRGPGDVGDTKNFEQSGYSGFRVADPVR
EECCHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCCCCCCCHHCCCCCCEECCCCC
DYPILQVAREAAFELLRKEKGSSEAR
CCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876