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The map label for this gene is mglC

Identifier: 189025911

GI number: 189025911

Start: 752546

End: 754141

Strand: Direct

Name: mglC

Synonym: TPASS_0686

Alternate gene names: 189025911

Gene position: 752546-754141 (Clockwise)

Preceding gene: 189025910

Following gene: 189025919

Centisome position: 66.04

GC content: 51.94

Gene sequence:

>1596_bases
ATGCGCGATCGTACACAGTGTGTGGCGGTGCCAACTCAAGCGTTCAATGAGATTTTAGATCAGGACGGTCAGCTCACCGC
GTACGCCCAAAGGCTCGAGCAGTTACGAGAGCGCGGTTCCCATAGGGTTGCCTTGCTCCGCGGGGAGCTTGCGCGCATAC
GGCAGGATCAGGTCTTGGGCATGCCGGAGAAAAGGGTGCAGGTTGCGGCGCACAGGCTCAAGATTTCCGAAGCGCAGGCC
GTTGCACGACAGTGCAAAACTGAGGAAACGCAGTTGGTTAGGAAGGCTGTCGCGCGTGTAAGGGGGCTCTTTCGAGACTT
TGACTGCTCTGTGCGCGACGCGATGCGCGAACAGCGGCTCTTGCTAAAGCAAGTTGCGACGGTGCAGCACACCTCTGCCT
CATCTGACCAAAGAGAGCACTGTCTGGCTCAGCTCCGGCAATGCAAGGAGGCGCGACACCACGCCTACCGTTCCTTGGTC
GAAAAGAGCGCTGCGCTGCGGAACGGGAAAATGACGTTTATCGAGCGCGTGGTGCGTGCTCTTAGAGAATATTCGTTCAA
TTTTGACGCAACCCAGTTCTTCCTCGCAAATGGTTTGTACATTGCTATTGCGGTATTCTTTATTGCGTGCATCGTAGTTG
CACCTTTCTCTGGTAATGGCAATCTTCTTACCATTCCCAACATTCTCACCATACTGGAGCAGTCTTCAGTGCGCATGTTC
TATGCGGTGGGAGTAGCAGGTATTATCCTGCTGGCAGGAACTGACCTCAGCATTGGGCGTATGGTGGCAATGGGGTCTGT
AGTCACGGGTATTATTCTTCATCCGGGACAGAATATCGTTACATTTTTTGGACTGGGGCCGTGGGATTTTACCCCTGTCC
CCATGGCTGTCCGTGTAGTCATGTCACTTGCAGTTTCTGTCGCACTTTGCGTTTCGTTCAGCCTATTTGCAGGATTCTTT
TCTGCTCGCCTCAAAATACACCCTTTCATTTCAACTCTTGCAACGCAGCTTATCATCTACGGGGTTTTGTTTTTTGGGAC
AAGTGGTACGCCAGTTGGCTCTATTGACCCATACATCAAAGACCTATTCGGTGGGCGGTGGATTCTAGGCACCATGCAGG
GCACACTCGTGACCTTCCCAAAGCTGATAATTCCTGCCACCATTGCGGTGGCCATCGCGTGGTTCATTTGGAACAAGACG
ATTCTAGGAAAAAATATGTACGCCGTTGGAGGGAATGCTGAGGCAGCGAATGTTAGCGGCATCAGTGTTTTCGGGGTGAC
TATGAGCGTTTTTGCAATGGCAGCTGTGTTTTATGGCTTTGGCGCGTTTTTTGAGACGTTCAAGGCAAATGCAAGTGCGG
GCACTGGTCAGGGTTATGAGCTCGACGCAATTGCCTCCTGTGTGGTAGGGGGTATCTCCTTCAACGGGGGAATCGGAAAA
CTCGAGGGTGCCGTGGTAGGCGTAATCATTTTCACCGGTCTTACCTATTGTCTGACTTTTTTAGGCATCGATACAAATCT
TCAGTTCGTGTTCAAGGGTTTGATCATCATCGCTGCAGTTGCACTCGACAGTGTGAAGTATCTGAAACGCCGCTAG

Upstream 100 bases:

>100_bases
TGTCCAATTATCGATTGGCTGGGATTGTGGATACAAAGAGTACCGATCAGGAAGCCTTGCTCAGACTTTCTGCGCGATAC
CTGTAGGGAGGAGCAGATAC

Downstream 100 bases:

>100_bases
TTCTTGCCCCGCTGGGCGGGACGTCAACGTTCACAATACGAATAAGCCGGGCGCCTTTCTGGGCCATTGTTCCCTCTTTG
GCTAACTCAGGGTGTGGGCT

Product: methylgalactoside ABC transporter, permease protein

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MRDRTQCVAVPTQAFNEILDQDGQLTAYAQRLEQLRERGSHRVALLRGELARIRQDQVLGMPEKRVQVAAHRLKISEAQA
VARQCKTEETQLVRKAVARVRGLFRDFDCSVRDAMREQRLLLKQVATVQHTSASSDQREHCLAQLRQCKEARHHAYRSLV
EKSAALRNGKMTFIERVVRALREYSFNFDATQFFLANGLYIAIAVFFIACIVVAPFSGNGNLLTIPNILTILEQSSVRMF
YAVGVAGIILLAGTDLSIGRMVAMGSVVTGIILHPGQNIVTFFGLGPWDFTPVPMAVRVVMSLAVSVALCVSFSLFAGFF
SARLKIHPFISTLATQLIIYGVLFFGTSGTPVGSIDPYIKDLFGGRWILGTMQGTLVTFPKLIIPATIAVAIAWFIWNKT
ILGKNMYAVGGNAEAANVSGISVFGVTMSVFAMAAVFYGFGAFFETFKANASAGTGQGYELDAIASCVVGGISFNGGIGK
LEGAVVGVIIFTGLTYCLTFLGIDTNLQFVFKGLIIIAAVALDSVKYLKRR

Sequences:

>Translated_531_residues
MRDRTQCVAVPTQAFNEILDQDGQLTAYAQRLEQLRERGSHRVALLRGELARIRQDQVLGMPEKRVQVAAHRLKISEAQA
VARQCKTEETQLVRKAVARVRGLFRDFDCSVRDAMREQRLLLKQVATVQHTSASSDQREHCLAQLRQCKEARHHAYRSLV
EKSAALRNGKMTFIERVVRALREYSFNFDATQFFLANGLYIAIAVFFIACIVVAPFSGNGNLLTIPNILTILEQSSVRMF
YAVGVAGIILLAGTDLSIGRMVAMGSVVTGIILHPGQNIVTFFGLGPWDFTPVPMAVRVVMSLAVSVALCVSFSLFAGFF
SARLKIHPFISTLATQLIIYGVLFFGTSGTPVGSIDPYIKDLFGGRWILGTMQGTLVTFPKLIIPATIAVAIAWFIWNKT
ILGKNMYAVGGNAEAANVSGISVFGVTMSVFAMAAVFYGFGAFFETFKANASAGTGQGYELDAIASCVVGGISFNGGIGK
LEGAVVGVIIFTGLTYCLTFLGIDTNLQFVFKGLIIIAAVALDSVKYLKRR
>Mature_531_residues
MRDRTQCVAVPTQAFNEILDQDGQLTAYAQRLEQLRERGSHRVALLRGELARIRQDQVLGMPEKRVQVAAHRLKISEAQA
VARQCKTEETQLVRKAVARVRGLFRDFDCSVRDAMREQRLLLKQVATVQHTSASSDQREHCLAQLRQCKEARHHAYRSLV
EKSAALRNGKMTFIERVVRALREYSFNFDATQFFLANGLYIAIAVFFIACIVVAPFSGNGNLLTIPNILTILEQSSVRMF
YAVGVAGIILLAGTDLSIGRMVAMGSVVTGIILHPGQNIVTFFGLGPWDFTPVPMAVRVVMSLAVSVALCVSFSLFAGFF
SARLKIHPFISTLATQLIIYGVLFFGTSGTPVGSIDPYIKDLFGGRWILGTMQGTLVTFPKLIIPATIAVAIAWFIWNKT
ILGKNMYAVGGNAEAANVSGISVFGVTMSVFAMAAVFYGFGAFFETFKANASAGTGQGYELDAIASCVVGGISFNGGIGK
LEGAVVGVIIFTGLTYCLTFLGIDTNLQFVFKGLIIIAAVALDSVKYLKRR

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI1788471, Length=338, Percent_Identity=39.9408284023669, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1790191, Length=307, Percent_Identity=31.2703583061889, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI145693152, Length=340, Percent_Identity=28.5294117647059, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790524, Length=324, Percent_Identity=31.4814814814815, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789992, Length=138, Percent_Identity=38.4057971014493, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788896, Length=324, Percent_Identity=27.1604938271605, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87082395, Length=297, Percent_Identity=29.96632996633, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGLC_TREPA (Q57321)

Other databases:

- EMBL:   U48416
- EMBL:   U45323
- EMBL:   AE000520
- PIR:   JC5172
- RefSeq:   NP_219123.1
- ProteinModelPortal:   Q57321
- IntAct:   Q57321
- GeneID:   2611431
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0686
- NMPDR:   fig|243276.1.peg.682
- TIGR:   TP_0686
- HOGENOM:   HBG663180
- OMA:   DFFKQNA
- ProtClustDB:   CLSK218818
- BioCyc:   TPAL243276:TP_0686-MONOMER
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 57876; Mature: 57876

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21630c94)-; HASH(0x20b46fa4)-; HASH(0x215a1910)-; HASH(0x21582950)-; HASH(0x215ab2ac)-; HASH(0x20b86e64)-; HASH(0x215ade30)-; HASH(0x20cbe568)-; HASH(0x21907010)-; HASH(0x21584974)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDRTQCVAVPTQAFNEILDQDGQLTAYAQRLEQLRERGSHRVALLRGELARIRQDQVLG
CCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCC
MPEKRVQVAAHRLKISEAQAVARQCKTEETQLVRKAVARVRGLFRDFDCSVRDAMREQRL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LLKQVATVQHTSASSDQREHCLAQLRQCKEARHHAYRSLVEKSAALRNGKMTFIERVVRA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LREYSFNFDATQFFLANGLYIAIAVFFIACIVVAPFSGNGNLLTIPNILTILEQSSVRMF
HHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCHHHH
YAVGVAGIILLAGTDLSIGRMVAMGSVVTGIILHPGQNIVTFFGLGPWDFTPVPMAVRVV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCHHHHHHHH
MSLAVSVALCVSFSLFAGFFSARLKIHPFISTLATQLIIYGVLFFGTSGTPVGSIDPYIK
HHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DLFGGRWILGTMQGTLVTFPKLIIPATIAVAIAWFIWNKTILGKNMYAVGGNAEAANVSG
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
ISVFGVTMSVFAMAAVFYGFGAFFETFKANASAGTGQGYELDAIASCVVGGISFNGGIGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCH
LEGAVVGVIIFTGLTYCLTFLGIDTNLQFVFKGLIIIAAVALDSVKYLKRR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MRDRTQCVAVPTQAFNEILDQDGQLTAYAQRLEQLRERGSHRVALLRGELARIRQDQVLG
CCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCC
MPEKRVQVAAHRLKISEAQAVARQCKTEETQLVRKAVARVRGLFRDFDCSVRDAMREQRL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LLKQVATVQHTSASSDQREHCLAQLRQCKEARHHAYRSLVEKSAALRNGKMTFIERVVRA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LREYSFNFDATQFFLANGLYIAIAVFFIACIVVAPFSGNGNLLTIPNILTILEQSSVRMF
HHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCHHHH
YAVGVAGIILLAGTDLSIGRMVAMGSVVTGIILHPGQNIVTFFGLGPWDFTPVPMAVRVV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCHHHHHHHH
MSLAVSVALCVSFSLFAGFFSARLKIHPFISTLATQLIIYGVLFFGTSGTPVGSIDPYIK
HHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DLFGGRWILGTMQGTLVTFPKLIIPATIAVAIAWFIWNKTILGKNMYAVGGNAEAANVSG
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
ISVFGVTMSVFAMAAVFYGFGAFFETFKANASAGTGQGYELDAIASCVVGGISFNGGIGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCH
LEGAVVGVIIFTGLTYCLTFLGIDTNLQFVFKGLIIIAAVALDSVKYLKRR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8921855; 8988365; 9665876