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The map label for this gene is asnC

Identifier: 189025835

GI number: 189025835

Start: 661119

End: 662690

Strand: Direct

Name: asnC

Synonym: TPASS_0609

Alternate gene names: 189025835

Gene position: 661119-662690 (Clockwise)

Preceding gene: 189025820

Following gene: 189025836

Centisome position: 58.02

GC content: 59.29

Gene sequence:

>1572_bases
GTGCGTGCTATGCACCCTTTGCTCAAGGAGATTCTGACTCATCCCCCCTCAGGCCAGCACGAATGCGTTCACGGTTGGGT
GCGCTCCAAACGGGAGACAAAACGCGCTGTCTTTATCAGTCTGAGCGACGGTTCTTGCCCTGATACCCTTCAGGTTACCG
TTCCCCTGCCCGAGTGTTCCGCCTCCCTTTCCTCTGGGGCGCAAGCTGAGCAAATCCCTAATGTCCGCGACGCTGTCCTC
CAGGGGGAAACGCTCGCTCAAACGCTCAAACGCGTTACTACCGGCGCCTGCATTCGCGCCGAGGGTGCACTCGTCCCCTC
CCCAGGCGCCGGGCAAGCGCTTGAGTTGCGCGCTTGCAACCTGACTGTTCTTGGCGAGGCGCCTGCTGAAACCTATCCTT
TGCAGAAGAAATCGCATAGTTTTGAGTTTTTGCGTGCGCACGCCCATCTGCGCGCGCGCACTAGTACCTTTGCCGCGTGT
GCACGGGTGCGCAGTGCACTTGCAGGCGCTGTCCACCGCTTTTTCTCCGAGCGACACTTTCAGTACGTGCACACACCGAT
CATTACCGCTTCGGACTGCGAGGGTGCAGGCGAGCTCTTTCGCGTCACTACTTTTGATCCCGTGCGTATTGCGCGCGAAG
CACACGCAGCGGGCGCGGCAGGCAACCCCTACGCACTCACGTACGCGGACGACTTTTTTGGTAAGGCAGCGCGCCTAACC
GTTTCGGGCCAACTGCAGGGGGAAGCATATGCGCTTGCCCTCACGCGCATCTACACCTTCGGCCCTACTTTTCGCGCAGA
GAACTCAAATACTAGCCGCCATCTTTCTGAGTTCTGGATGGTGGAGCCGGAAATCGCCTTTGCACGCATCACTGACTGCA
TGGACGTGGCAGAGGAGTTTTTGGCGTACCTGCTACGCGCAGCACTCAAGGACTGCGCGCAGGATATAGCCTTCCTTGAC
GAGCGCGCAGCGCAGCATGCGCGAAGCGCGCGGGGCGACACACCCCTTGCCGCGCGCAGCACAGCGCGCACACCGCCAGT
GCGGACGCCAGGGCAGCTGACGCGCATGCTCGAAGACGTCGCCCGCGCGCCTGCCACGCGCCTGACATACACAGAGGCAA
TTAAACTACTGGAGAACAGTGGGCGCTCCTTTGAGTTCCCCGTACGCTGGGGATGCGATTTACAAAGCGAGCACGAGTGT
TTTTTAACAGAAGAGGTGTTCCACGGCCCGGTGATTGTCTATGACTACCCAAAGGAAATCAAGGCCTTCTACATGAAGCT
CAATGCCGACGGCACAACGGTGCGTTCCATGGACCTGCTAGTTCCGGGATTAGGGGAGATTATGGGAGGCTCGGAGCGCG
AGGAACAGTTTGAAGTACTCTGTGCTCGCATCCGTGCCAGCGGTTTTGACCCTCACGACTATCGCTGGTACACCGATCTC
CGTCGCTTTGGTACCGCGCCCCATGCAGGTTTTGGACTCGGCTTCGAGCGCTTGCTGCAGTACGTCACCGGGCTTGGGAA
TATTCGGGATGTTATTCCGTTTCCTCGTACGCCGCGCACTGCGGACTTTTAG

Upstream 100 bases:

>100_bases
CTGCGCGGCGTTCCATGCAGATGCCGCGCAGGGCGTGCGCCGTGGCGTCACAGCTGCTTGCCGGTCCACGCCCTTCCACA
AAGAGGGTAAAAGCGTTAGA

Downstream 100 bases:

>100_bases
GATGGAGCCATGAAAGGAGTACGCTGTCCCTGTCTTTATGCCTGCAGGGTGTTGTACTCTCAAAGCAAAATCCGGCGGCG
ACGCACGCTGCTGTCTCCGT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQIPNVRDAVL
QGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAAC
ARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLT
VSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLD
ERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHEC
FLTEEVFHGPVIVYDYPKEIKAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDL
RRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF

Sequences:

>Translated_523_residues
MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQIPNVRDAVL
QGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAAC
ARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLT
VSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLD
ERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHEC
FLTEEVFHGPVIVYDYPKEIKAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDL
RRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF
>Mature_523_residues
MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQIPNVRDAVL
QGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAAC
ARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLT
VSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLD
ERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHEC
FLTEEVFHGPVIVYDYPKEIKAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDL
RRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=508, Percent_Identity=37.4015748031496, Blast_Score=341, Evalue=1e-93,
Organism=Homo sapiens, GI4758762, Length=511, Percent_Identity=26.614481409002, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI45439306, Length=375, Percent_Identity=27.4666666666667, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1787161, Length=505, Percent_Identity=48.9108910891089, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17556372, Length=483, Percent_Identity=31.055900621118, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71984122, Length=506, Percent_Identity=27.8656126482213, Blast_Score=154, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6319872, Length=505, Percent_Identity=35.8415841584158, Blast_Score=299, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6321807, Length=518, Percent_Identity=27.7992277992278, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=379, Percent_Identity=27.4406332453826, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19922416, Length=518, Percent_Identity=31.0810810810811, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19921528, Length=505, Percent_Identity=27.3267326732673, Blast_Score=145, Evalue=8e-35,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_TREPA (O83618)

Other databases:

- EMBL:   AE000520
- PIR:   F71302
- RefSeq:   NP_219047.1
- ProteinModelPortal:   O83618
- SMR:   O83618
- GeneID:   2611624
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0609
- NMPDR:   fig|243276.1.peg.606
- TIGR:   TP_0609
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   TPAL243276:TP_0609-MONOMER
- BRENDA:   6.1.1.22
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 57798; Mature: 57798

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECS
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCHHH
ASLSSGAQAEQIPNVRDAVLQGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACN
HHHHCCCCHHHCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECC
LTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHF
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLT
EEECCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECHHHCCCEEEEE
VSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEF
EECEECCCHHEEEEHHHHHCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LAYLLRAALKDCAQDIAFLDERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHECFLTEEVFHGPVIVYDYPKEI
HHCCCHHHHHHHHHHHHHCCCCCEECCEEECCCCCCCCCEEEEHHHHCCCEEEEECCHHH
KAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDL
EEEEEEECCCCCEEEEHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF
HHHCCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECS
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCHHH
ASLSSGAQAEQIPNVRDAVLQGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACN
HHHHCCCCHHHCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECC
LTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHF
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLT
EEECCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECHHHCCCEEEEE
VSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEF
EECEECCCHHEEEEHHHHHCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LAYLLRAALKDCAQDIAFLDERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHECFLTEEVFHGPVIVYDYPKEI
HHCCCHHHHHHHHHHHHHCCCCCEECCEEECCCCCCCCCEEEEHHHHCCCEEEEECCHHH
KAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDL
EEEEEEECCCCCEEEEHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF
HHHCCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876