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The map label for this gene is atpD2

Identifier: 189025756

GI number: 189025756

Start: 571630

End: 572259

Strand: Reverse

Name: atpD2

Synonym: TPASS_0527

Alternate gene names: 189025756

Gene position: 572259-571630 (Counterclockwise)

Preceding gene: 189025757

Following gene: 189025753

Centisome position: 50.22

GC content: 52.7

Gene sequence:

>630_bases
GTGAAAACACCTTTAGCTCCCACCAAGTCGAATTTGGCGTATGTAAGAGATCAGTTGGGTTTGGCTCGTGATGGTTATCG
CTTGCTTGAGCAAAAACGAGAAATCCTCTTTATGGAGCTCACTTCTCTCTTGGAAGAGGTGCATCTTCTAGAGACTGAGC
TTGATAAGCGTCGGAAGCAGGCGTATGCGTCGCTGTGGCAGCTGCTTCTTGCACAGGGCCGCGATGATATTGCTGCCTGT
GCGCTCGTAACACCGGTGCCCTGCCGTGTGCAGCAGGAGGTGCTTTTAATTGCTGGATTGCGATTTCTCCGTCTGGATGC
AGTGATGCAGCCACCGAAGCTGCAGTATGCTGCGCTCGGCTCCAGCGCGTGCATGGATAGAGCGCGGGAGGACTTCGGGT
TACTGTTGCAAACACTCACGAGAATGGCATCCGTACAGACTATCGTATGGAGACTCGCGTCAGAAATGAGAAAAACACAG
CGACGTGTGAATGCGCTGAGCAAGCAGATAATCCCACAGATGTGCGAGACGTGCATGTACATCGAAAGCGTGCTCGAGGA
GCGCGATCGGGAAAGTACTTTTGTGCTCAAATCGCTAAAGGCGCGCAAGGATCCCACAACCACCCTTTAG

Upstream 100 bases:

>100_bases
GCGTAAAGACCATGTGTCCTATAAGGCTCTTGGAGAAGGGTGATTTCTTTGCGGCGCTCCCTTGCTGTGTGTCTTGGCCA
CGCAGGGAGAGGATACAGAG

Downstream 100 bases:

>100_bases
CACTCATCCGGCTGTACGTCCTGCGCTGCTGTTGTTCCGGGCCGACGCTACCTCAGGGAGGCGCGTCCGACACGCACTCT
TCTTTTCCGCGGCCCTTTGC

Product: V-type ATPase, subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D 2

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKTPLAPTKSNLAYVRDQLGLARDGYRLLEQKREILFMELTSLLEEVHLLETELDKRRKQAYASLWQLLLAQGRDDIAAC
ALVTPVPCRVQQEVLLIAGLRFLRLDAVMQPPKLQYAALGSSACMDRAREDFGLLLQTLTRMASVQTIVWRLASEMRKTQ
RRVNALSKQIIPQMCETCMYIESVLEERDRESTFVLKSLKARKDPTTTL

Sequences:

>Translated_209_residues
MKTPLAPTKSNLAYVRDQLGLARDGYRLLEQKREILFMELTSLLEEVHLLETELDKRRKQAYASLWQLLLAQGRDDIAAC
ALVTPVPCRVQQEVLLIAGLRFLRLDAVMQPPKLQYAALGSSACMDRAREDFGLLLQTLTRMASVQTIVWRLASEMRKTQ
RRVNALSKQIIPQMCETCMYIESVLEERDRESTFVLKSLKARKDPTTTL
>Mature_209_residues
MKTPLAPTKSNLAYVRDQLGLARDGYRLLEQKREILFMELTSLLEEVHLLETELDKRRKQAYASLWQLLLAQGRDDIAAC
ALVTPVPCRVQQEVLLIAGLRFLRLDAVMQPPKLQYAALGSSACMDRAREDFGLLLQTLTRMASVQTIVWRLASEMRKTQ
RRVNALSKQIIPQMCETCMYIESVLEERDRESTFVLKSLKARKDPTTTL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320784, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATD2_TREPA (O83539)

Other databases:

- EMBL:   AE000520
- PIR:   A71313
- RefSeq:   NP_218967.1
- ProteinModelPortal:   O83539
- IntAct:   O83539
- GeneID:   2610777
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0527
- NMPDR:   fig|243276.1.peg.526
- TIGR:   TP_0527
- HOGENOM:   HBG732046
- OMA:   TQKRANA
- ProtClustDB:   CLSK2300235
- BioCyc:   TPAL243276:TP_0527-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_00271
- InterPro:   IPR002699
- PANTHER:   PTHR11671
- TIGRFAMs:   TIGR00309

Pfam domain/function: PF01813 ATP-synt_D

EC number: 3.6.3.14

Molecular weight: Translated: 23926; Mature: 23926

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPLAPTKSNLAYVRDQLGLARDGYRLLEQKREILFMELTSLLEEVHLLETELDKRRKQ
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYASLWQLLLAQGRDDIAACALVTPVPCRVQQEVLLIAGLRFLRLDAVMQPPKLQYAALG
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
SSACMDRAREDFGLLLQTLTRMASVQTIVWRLASEMRKTQRRVNALSKQIIPQMCETCMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESVLEERDRESTFVLKSLKARKDPTTTL
HHHHHHHHCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTPLAPTKSNLAYVRDQLGLARDGYRLLEQKREILFMELTSLLEEVHLLETELDKRRKQ
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYASLWQLLLAQGRDDIAACALVTPVPCRVQQEVLLIAGLRFLRLDAVMQPPKLQYAALG
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
SSACMDRAREDFGLLLQTLTRMASVQTIVWRLASEMRKTQRRVNALSKQIIPQMCETCMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESVLEERDRESTFVLKSLKARKDPTTTL
HHHHHHHHCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876