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The map label for this gene is murG

Identifier: 189025752

GI number: 189025752

Start: 564926

End: 566080

Strand: Reverse

Name: murG

Synonym: TPASS_0523

Alternate gene names: 189025752

Gene position: 566080-564926 (Counterclockwise)

Preceding gene: 189025753

Following gene: 189025751

Centisome position: 49.68

GC content: 52.9

Gene sequence:

>1155_bases
ATGCGCTTTCGTGCACGCGTATCTCAGTCAACTGCGAAGTGCGTCGTGTTCACAGGAGGCGGCACGGGAGGACACATTTT
CCCGGGAATTGCAGTTTTTCAAGCGCTTGCGCAGCAGGCGGCGGTGCGTGTCGTGTGGATTGGTGCAGCGCGTGGTGCTG
ATCGCTCCATAGTGGAATCTGCCGGATTAGAGTTTTGTGGTATCACCGCTGGCAAGTGGCGTCGGTACGCGAGTGTGCGC
AATTTTTTTGATGTATTTCGAGTGCTCGTCGGTACGGTGCAATCCTATTGTATCTTGCGCGCTTTGCGCCCGCAGGCACT
ATTTTCTAAGGGAGGGTTTGTGTCCGTGCCGCCGTGCATCGCAGCGTGGCTTTTGCGCATACCCGTTGTCACGCATGAAT
CGGATATCAGTCCAGGACTTGCCACACGCATCAATGCGCGTTTCGCCGATCGTATTTTAGTCTCTTATCCGCACACGTCC
TGTTATTTTCCCCGTGCGCGACGCGCAGCAGTTCACTGCACGGGGAATCCTGTGCGACAAGATTTTTTTTCTGCACAGGC
AGAGCGTGCATACCAGTTTTTACGCATTGACCAAAAAAAGCCATTGCTCACAGTCCTCGGAGGAAGTAGCGGTGCGCGTG
ACCTAAACGCGCGTGTTCTTTCATGTAGCACCTTCCTTACCGAACGCTTCTATCTTGTCCATCAATTTGGCGCAGGCAAC
GAGGACCAAATGCATACTATCACCAATTCGCTTAGCGTCAATGCTCGGCATGCCTACATGTCGTTTCCTTTCATTCAGGC
ACATCTGCCCGATATACTCGCCGCGAGCGCACTGGTACTCTCTCGTGCTGGTGCGAACGCGGTGTGGGAGTGCGCAGTGC
TCGGTAAACCAATGATTCTTTTTCCTCTCGAACGAGGGAGTTCCCGTGGGGATCAGATTGAAAATGCAGAATATTTTAGC
GCACACGGTGCTGCGTGCATCCTTCGTGCTCAAGATGAAAAGGGACATCAACTGGTGTCTTTGCTCACAGAACTGTTCCA
TCCTTCCTGCGCTAGGATAGAGGAGATGGCACGTGCGTCTTACACACTTGGAATTGGCAATGCCGCGTATGATATTGCGC
AGCAGTTGCAGACTTTCATAAAGGAGGGGATGTGA

Upstream 100 bases:

>100_bases
GATGGAAGAGGTCCTTTCTCTCGCCTTCCCCAAGGGGAAGCGTGTCCGTGCTGGCACTGCCGCCCAATCTGCTTCTCCTG
AAACCCTTACAGGCTGACGT

Downstream 100 bases:

>100_bases
CAATCAGTACCCTGGATCTCATTCTTGGAATCATCATGGGGATAGTGACCGTCCGTGCCACCATGCGCGGGTTTGTCGAT
GAGTTCTTTTCTAAGGCAAG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVESAGLEFCGITAGKWRRYASVR
NFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCIAAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTS
CYFPRARRAAVHCTGNPVRQDFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGN
EDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMILFPLERGSSRGDQIENAEYFS
AHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARASYTLGIGNAAYDIAQQLQTFIKEGM

Sequences:

>Translated_384_residues
MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVESAGLEFCGITAGKWRRYASVR
NFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCIAAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTS
CYFPRARRAAVHCTGNPVRQDFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGN
EDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMILFPLERGSSRGDQIENAEYFS
AHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARASYTLGIGNAAYDIAQQLQTFIKEGM
>Mature_384_residues
MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVESAGLEFCGITAGKWRRYASVR
NFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCIAAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTS
CYFPRARRAAVHCTGNPVRQDFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGN
EDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMILFPLERGSSRGDQIENAEYFS
AHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARASYTLGIGNAAYDIAQQLQTFIKEGM

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=351, Percent_Identity=28.7749287749288, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_TREPA (O83535)

Other databases:

- EMBL:   AE000520
- PIR:   A71316
- RefSeq:   NP_218963.1
- ProteinModelPortal:   O83535
- GeneID:   2610738
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0523
- NMPDR:   fig|243276.1.peg.522
- TIGR:   TP_0523
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK00726
- BioCyc:   TPAL243276:TP_0523-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 42050; Mature: 42050

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVES
CCCHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHH
AGLEFCGITAGKWRRYASVRNFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCI
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEECCHHH
AAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTSCYFPRARRAAVHCTGNPVRQ
HHHHHHCCCEECCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCCEEEEECCCHHHH
DFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGN
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEHHHHHHHHHHHHEEECCCCC
EDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMIL
CCHHHHHHHCCCCCEEEHEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCEEE
FPLERGSSRGDQIENAEYFSAHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARAS
EEECCCCCCCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
YTLGIGNAAYDIAQQLQTFIKEGM
EEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVES
CCCHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHH
AGLEFCGITAGKWRRYASVRNFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCI
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEECCHHH
AAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTSCYFPRARRAAVHCTGNPVRQ
HHHHHHCCCEECCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCCEEEEECCCHHHH
DFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGN
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEHHHHHHHHHHHHEEECCCCC
EDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMIL
CCHHHHHHHCCCCCEEEHEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCEEE
FPLERGSSRGDQIENAEYFSAHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARAS
EEECCCCCCCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
YTLGIGNAAYDIAQQLQTFIKEGM
EEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876