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The map label for this gene is lnt

Identifier: 189025650

GI number: 189025650

Start: 445215

End: 446894

Strand: Reverse

Name: lnt

Synonym: TPASS_0417

Alternate gene names: 189025650

Gene position: 446894-445215 (Counterclockwise)

Preceding gene: 189025667

Following gene: 189025649

Centisome position: 39.22

GC content: 57.42

Gene sequence:

>1680_bases
ATGCTTTGCACAGCGCCTCTTGTTTCAAGCGCCGCCTCGGCGGTGCTCTTGGCATTTGCGATTCCCAACGAGTTTTGGCT
CGCCGGTTCCTCCGTGCTAGGGTTGGGGGCGCTTGTTCCCTTGTACGTTGGATTCCTCCTCTCCCCTGCAAAAAAACACG
TTGCCTGTTCTTATGGGCTGTTCGTCGCACTCGTGCACGCGTGTTCTAGCTTTTGGCTCAAAAACTTTCAGGGCTTCGCG
CTCTTCACCCTCGGCGCATCAACTGTCGGTTACTTCTTCTATGCGCTTCCTTTCGGCGTAGCGTTCGCATGCATCCTGCG
CAAGCAGGCGCCCGCGCGTGCCTGCGCTTTTGCGCTCGTGTGGACCCTCTGGGAATGGGTAAAGTCAACCGGTATACTCG
CCTACCCGTGGGGTACGGTCCCTATGACCGCGCACAGCCTCTCGCACCTCATACAGATAGCTGATATCACCGGCGTCTGG
GGGCTTTCCTTCCTCATCCCGCTCGCAAACGCGTGCGTTGCAGAAAGTCTCCACTTCTTCATAAAAAAGAGAGACAGCGT
CCCTGTGTTCCGTCTCTGGCTCCTCACCGGCTGCTTGTACTGCCTGTGCAGTCTCTACGGTGCCTACCGCATCGCCACCC
TTGGGGCTCCACGTACCACGCTCGCGTTGGCAATCGTACAGCAAAATGCAGATCCGTGGGATACAAYTTCCTTCGAAAAA
AACCTCACCACCGCTATACATCTGACTGAGACAGCCCTTCGTACGCAAACAGCTCCCCCCCTGCCGACTACTCCCTACAG
AAAAGAAAAAACACTCACACACGCTTCTGCGCGCGCACCTGTCGACATGGTGGTTTGGAGCGAGTCTAGTCTGCGCTATC
CGTACGAACAGTACCGTCACGTGTATAACGCATTGCCAGCGGCACGACCTTTCTCGGCGTTCTTGCGCACGCTCGGCGCG
CCCCTTCTGGTGGGAACCCCCTTGAGACTGTCTGGTAACTCCACTAAAGGTGGATACGCCAATGCAGTGGCCTTGCTCCG
CCCAGACGGGCACGTGGCGCAGGTATATGGCAAAATGCAGATGGTGCCATTTGCAGAATTCATTCCCTGGGGACACATGA
CATCTGTACAAAGACTGGCGCAGATGCTCGCCGGCTTTTCCGAAAGCTGGACGCCAGGGCCAGGGCCGCGCTTGTTTCAT
GTGCCGTGCGCCGCAGGAGGCAGCGTGCGCTTCGCAACTCCCATCTGTTACGAAGATGCCTTTCCTTCCCTCTGCGCCGC
TTTGCACACACAGGGGAGTGAGCTCCTTATTAATCTTACGAACGACTCTTGGTCAAAAACTGCCAGCGCAGAGTGGCAGC
ACTATGTTGTCTCTCTTTTTCGGGCCATAGAGCTGCGTACCACCCTCGTGCGCTCTACAAACTCTGGCTATACCGTCGTC
ATCGGCCCAGAGGGAAAAACGCGCGCCGCGTTTCCGTTGTTTCAGGCCACCAGCGCGGTGCTCCACGTTCCAGTGTACCC
GGTAGTGCGCACGTACTATGCGCGCATGAGAGATTGGGTGATCGTGCTGTGCGCGCTCATCTTTTTTGCAGAAGGAGTGC
GCATGGCCGTGCACACCCGCCGGCACAGCACCACGCAGGCGGAAAGCTCACTGCAGCAGATAAGGGGGGAGCATGTTTGA

Upstream 100 bases:

>100_bases
TACTCCTCTGTGTGGCAGGACTCTACCCGCTGCATGCGCAGCATCATAGCCAGTGTATTGAAATAATACAACAAAAATGC
TTTTCTGGCAGGGGAAAGTT

Downstream 100 bases:

>100_bases
GCAACTGAGCGCGAGCTTTAAACGTATCGTAGGAGCGCTGGGAGGACGCGCAACTATCAGCGAACGGAATATTCAAGAAG
CAGTAGAATCAATTAAGCGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase 2

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MLCTAPLVSSAASAVLLAFAIPNEFWLAGSSVLGLGALVPLYVGFLLSPAKKHVACSYGLFVALVHACSSFWLKNFQGFA
LFTLGASTVGYFFYALPFGVAFACILRKQAPARACAFALVWTLWEWVKSTGILAYPWGTVPMTAHSLSHLIQIADITGVW
GLSFLIPLANACVAESLHFFIKKRDSVPVFRLWLLTGCLYCLCSLYGAYRIATLGAPRTTLALAIVQQNADPWDTXSFEK
NLTTAIHLTETALRTQTAPPLPTTPYRKEKTLTHASARAPVDMVVWSESSLRYPYEQYRHVYNALPAARPFSAFLRTLGA
PLLVGTPLRLSGNSTKGGYANAVALLRPDGHVAQVYGKMQMVPFAEFIPWGHMTSVQRLAQMLAGFSESWTPGPGPRLFH
VPCAAGGSVRFATPICYEDAFPSLCAALHTQGSELLINLTNDSWSKTASAEWQHYVVSLFRAIELRTTLVRSTNSGYTVV
IGPEGKTRAAFPLFQATSAVLHVPVYPVVRTYYARMRDWVIVLCALIFFAEGVRMAVHTRRHSTTQAESSLQQIRGEHV

Sequences:

>Translated_559_residues
MLCTAPLVSSAASAVLLAFAIPNEFWLAGSSVLGLGALVPLYVGFLLSPAKKHVACSYGLFVALVHACSSFWLKNFQGFA
LFTLGASTVGYFFYALPFGVAFACILRKQAPARACAFALVWTLWEWVKSTGILAYPWGTVPMTAHSLSHLIQIADITGVW
GLSFLIPLANACVAESLHFFIKKRDSVPVFRLWLLTGCLYCLCSLYGAYRIATLGAPRTTLALAIVQQNADPWDTXSFEK
NLTTAIHLTETALRTQTAPPLPTTPYRKEKTLTHASARAPVDMVVWSESSLRYPYEQYRHVYNALPAARPFSAFLRTLGA
PLLVGTPLRLSGNSTKGGYANAVALLRPDGHVAQVYGKMQMVPFAEFIPWGHMTSVQRLAQMLAGFSESWTPGPGPRLFH
VPCAAGGSVRFATPICYEDAFPSLCAALHTQGSELLINLTNDSWSKTASAEWQHYVVSLFRAIELRTTLVRSTNSGYTVV
IGPEGKTRAAFPLFQATSAVLHVPVYPVVRTYYARMRDWVIVLCALIFFAEGVRMAVHTRRHSTTQAESSLQQIRGEHV
>Mature_559_residues
MLCTAPLVSSAASAVLLAFAIPNEFWLAGSSVLGLGALVPLYVGFLLSPAKKHVACSYGLFVALVHACSSFWLKNFQGFA
LFTLGASTVGYFFYALPFGVAFACILRKQAPARACAFALVWTLWEWVKSTGILAYPWGTVPMTAHSLSHLIQIADITGVW
GLSFLIPLANACVAESLHFFIKKRDSVPVFRLWLLTGCLYCLCSLYGAYRIATLGAPRTTLALAIVQQNADPWDTXSFEK
NLTTAIHLTETALRTQTAPPLPTTPYRKEKTLTHASARAPVDMVVWSESSLRYPYEQYRHVYNALPAARPFSAFLRTLGA
PLLVGTPLRLSGNSTKGGYANAVALLRPDGHVAQVYGKMQMVPFAEFIPWGHMTSVQRLAQMLAGFSESWTPGPGPRLFH
VPCAAGGSVRFATPICYEDAFPSLCAALHTQGSELLINLTNDSWSKTASAEWQHYVVSLFRAIELRTTLVRSTNSGYTVV
IGPEGKTRAAFPLFQATSAVLHVPVYPVVRTYYARMRDWVIVLCALIFFAEGVRMAVHTRRHSTTQAESSLQQIRGEHV

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=280, Percent_Identity=30.7142857142857, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT2_TREPA (O83432)

Other databases:

- EMBL:   AE000520
- PIR:   G71327
- RefSeq:   NP_218857.1
- ProteinModelPortal:   O83432
- GeneID:   2610888
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0417
- NMPDR:   fig|243276.1.peg.416
- TIGR:   TP_0417
- HOGENOM:   HBG250966
- OMA:   KGHIRGM
- ProtClustDB:   PRK00302
- BioCyc:   TPAL243276:TP_0417-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 61209; Mature: 61209

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1fb088b4)-; HASH(0x206ed62c)-; HASH(0x1f386b5c)-; HASH(0x20ee13c4)-; HASH(0x200f5d04)-; HASH(0x1f8f2f58)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCTAPLVSSAASAVLLAFAIPNEFWLAGSSVLGLGALVPLYVGFLLSPAKKHVACSYGL
CCCCCHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVALVHACSSFWLKNFQGFALFTLGASTVGYFFYALPFGVAFACILRKQAPARACAFALV
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
WTLWEWVKSTGILAYPWGTVPMTAHSLSHLIQIADITGVWGLSFLIPLANACVAESLHFF
HHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKRDSVPVFRLWLLTGCLYCLCSLYGAYRIATLGAPRTTLALAIVQQNADPWDTXSFEK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHEEEEEECCCCCCCCCCHHC
NLTTAIHLTETALRTQTAPPLPTTPYRKEKTLTHASARAPVDMVVWSESSLRYPYEQYRH
CCEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
VYNALPAARPFSAFLRTLGAPLLVGTPLRLSGNSTKGGYANAVALLRPDGHVAQVYGKMQ
HHHHCCCCCHHHHHHHHCCCCEEECCCEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHH
MVPFAEFIPWGHMTSVQRLAQMLAGFSESWTPGPGPRLFHVPCAAGGSVRFATPICYEDA
CCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEECCCHHHHH
FPSLCAALHTQGSELLINLTNDSWSKTASAEWQHYVVSLFRAIELRTTLVRSTNSGYTVV
HHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IGPEGKTRAAFPLFQATSAVLHVPVYPVVRTYYARMRDWVIVLCALIFFAEGVRMAVHTR
ECCCCCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RHSTTQAESSLQQIRGEHV
HCCHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MLCTAPLVSSAASAVLLAFAIPNEFWLAGSSVLGLGALVPLYVGFLLSPAKKHVACSYGL
CCCCCHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVALVHACSSFWLKNFQGFALFTLGASTVGYFFYALPFGVAFACILRKQAPARACAFALV
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
WTLWEWVKSTGILAYPWGTVPMTAHSLSHLIQIADITGVWGLSFLIPLANACVAESLHFF
HHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKRDSVPVFRLWLLTGCLYCLCSLYGAYRIATLGAPRTTLALAIVQQNADPWDTXSFEK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHEEEEEECCCCCCCCCCHHC
NLTTAIHLTETALRTQTAPPLPTTPYRKEKTLTHASARAPVDMVVWSESSLRYPYEQYRH
CCEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
VYNALPAARPFSAFLRTLGAPLLVGTPLRLSGNSTKGGYANAVALLRPDGHVAQVYGKMQ
HHHHCCCCCHHHHHHHHCCCCEEECCCEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHH
MVPFAEFIPWGHMTSVQRLAQMLAGFSESWTPGPGPRLFHVPCAAGGSVRFATPICYEDA
CCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEECCCHHHHH
FPSLCAALHTQGSELLINLTNDSWSKTASAEWQHYVVSLFRAIELRTTLVRSTNSGYTVV
HHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IGPEGKTRAAFPLFQATSAVLHVPVYPVVRTYYARMRDWVIVLCALIFFAEGVRMAVHTR
ECCCCCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RHSTTQAESSLQQIRGEHV
HCCHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876