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The map label for this gene is ftsZ

Identifier: 189025623

GI number: 189025623

Start: 415931

End: 417187

Strand: Direct

Name: ftsZ

Synonym: TPASS_0390

Alternate gene names: 189025623

Gene position: 415931-417187 (Clockwise)

Preceding gene: 189025622

Following gene: 189025624

Centisome position: 36.5

GC content: 50.28

Gene sequence:

>1257_bases
ATGATGAATATAGAGCTTGCACCTTCAGGCGAAGAGTTTACCCTAAGTCCAACGGTCATAAAGGTCATCGGTGCCGGTGG
TGGTGGGTCAAACGCGGTAAATAGGATGATGAGCTGCGGTTTGCAGTGCGTCGAGTTTATTGCAGCAAATACAGATGTGC
AGGCGTTGAGCTATTCTACCGCGCCTAAAAAGCTTGCCATTGGCACCAAGGTGACAAGGGGGTTGGGTGCAGGCGGTGAT
CCTGAGATTGGCGAGAAGGCTGCAATGGAAGATGCTGAAGCCATTGCAAGTGCGTTGCAGGGCGCGAACATGGTGTTCAT
CACCGCAGGGATGGGAGGAGGTACGGGAACAGGTGCTGCCCCAGTTATTGCAAAGATTGCACGGGAACTTGGTGCTTTGA
CAGTTGCCGTAGTCACGAAGCCGTTTCGCTTTGAAGGCAGAGCAAAGATGATGCTCGCTGAGCGAGGGATCGAAAAATTG
CGCACGCACTCGGACACCGTGATTGTGATCCCTAATCAGAATTTACTCAGTGTGGTAGATAAGCGCTGCCCGATTAAAGA
GACGTATCTGGTTGCAGATGATCTGCTGCGCAAGTCGGTGCAAAGTATTTCTGATTTAATTACCCTTCCTGGAGAAGTGA
ATTTAGATTTCATGGATGTAAAAAACACCATGGAAGGGCAGGGGTACGCGCTTATCGGTGTGGGAGAGGGAGAAGGGGAA
AACCGCGCAGTAGATGCGGCAACCGCTGCAATTAATAATCCGCTTTTGGAAGAGACGCGGATAGAAGGTGCTACCAGACT
GCTGGTTGCGGTACGTGGCTCAGAGAACTTGAGCATGGGAGAAGTCGATGGCGTGATGTCTGTGGTTGCAAAGACCATTG
ATCCGGATGCGATTATCATCCATGGCACGTCCATCGACGCGAGTATGCAGGATAGGGTGAGGGTTACGGTTATCGCAACG
GGTGTACCGCAAGCGAGTATTTCGATAGCGGGAGATACACACAGTTCTCAAAAGATAAAAACATCATCGTACGGTGCGGT
GAGTACCGGTGTGTATATTAGTTCTGACGAATGGAACAGAGCTAAAAGCTCTAAACAGCCAAACTTACCTGGTCTGGCTA
CGCGTAATAGCGCTGTTCAAGAAACGCGTATGGAAAAGAACGGAGTGAAGGGCCACACGTTTGGCGTTCCGCTCCCCTCG
GTAAATGAAGATTTGGATGAACCGACCTTTTTGAGAAATAGGAACAAGGGTCTGTGA

Upstream 100 bases:

>100_bases
GGAGCGTGCGGGAGTGTTTACTAAAGTGAAGGATATTTGGAGGAACTTGTTTTAAACCGCGCACAGCATGCGGCACGCGG
TGTAGGGGAATGGGAGGGGA

Downstream 100 bases:

>100_bases
AAGACGTCGATATCCGTGTGCAATCCTTTTACGCGTACTTAATTTCGGCAGAGGCGCACGCGCTTTTGACCGCACGGACG
TACGTGACTACGTTGATGCT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MMNIELAPSGEEFTLSPTVIKVIGAGGGGSNAVNRMMSCGLQCVEFIAANTDVQALSYSTAPKKLAIGTKVTRGLGAGGD
PEIGEKAAMEDAEAIASALQGANMVFITAGMGGGTGTGAAPVIAKIARELGALTVAVVTKPFRFEGRAKMMLAERGIEKL
RTHSDTVIVIPNQNLLSVVDKRCPIKETYLVADDLLRKSVQSISDLITLPGEVNLDFMDVKNTMEGQGYALIGVGEGEGE
NRAVDAATAAINNPLLEETRIEGATRLLVAVRGSENLSMGEVDGVMSVVAKTIDPDAIIIHGTSIDASMQDRVRVTVIAT
GVPQASISIAGDTHSSQKIKTSSYGAVSTGVYISSDEWNRAKSSKQPNLPGLATRNSAVQETRMEKNGVKGHTFGVPLPS
VNEDLDEPTFLRNRNKGL

Sequences:

>Translated_418_residues
MMNIELAPSGEEFTLSPTVIKVIGAGGGGSNAVNRMMSCGLQCVEFIAANTDVQALSYSTAPKKLAIGTKVTRGLGAGGD
PEIGEKAAMEDAEAIASALQGANMVFITAGMGGGTGTGAAPVIAKIARELGALTVAVVTKPFRFEGRAKMMLAERGIEKL
RTHSDTVIVIPNQNLLSVVDKRCPIKETYLVADDLLRKSVQSISDLITLPGEVNLDFMDVKNTMEGQGYALIGVGEGEGE
NRAVDAATAAINNPLLEETRIEGATRLLVAVRGSENLSMGEVDGVMSVVAKTIDPDAIIIHGTSIDASMQDRVRVTVIAT
GVPQASISIAGDTHSSQKIKTSSYGAVSTGVYISSDEWNRAKSSKQPNLPGLATRNSAVQETRMEKNGVKGHTFGVPLPS
VNEDLDEPTFLRNRNKGL
>Mature_418_residues
MMNIELAPSGEEFTLSPTVIKVIGAGGGGSNAVNRMMSCGLQCVEFIAANTDVQALSYSTAPKKLAIGTKVTRGLGAGGD
PEIGEKAAMEDAEAIASALQGANMVFITAGMGGGTGTGAAPVIAKIARELGALTVAVVTKPFRFEGRAKMMLAERGIEKL
RTHSDTVIVIPNQNLLSVVDKRCPIKETYLVADDLLRKSVQSISDLITLPGEVNLDFMDVKNTMEGQGYALIGVGEGEGE
NRAVDAATAAINNPLLEETRIEGATRLLVAVRGSENLSMGEVDGVMSVVAKTIDPDAIIIHGTSIDASMQDRVRVTVIAT
GVPQASISIAGDTHSSQKIKTSSYGAVSTGVYISSDEWNRAKSSKQPNLPGLATRNSAVQETRMEKNGVKGHTFGVPLPS
VNEDLDEPTFLRNRNKGL

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=47.6027397260274, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FTSZ_TREPA (O83405)

Other databases:

- EMBL:   AE000520
- PIR:   H71331
- RefSeq:   NP_218830.1
- ProteinModelPortal:   O83405
- SMR:   O83405
- IntAct:   O83405
- GeneID:   2610732
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0390
- NMPDR:   fig|243276.1.peg.389
- TIGR:   TP_0390
- HOGENOM:   HBG478075
- OMA:   DVLRMGV
- ProtClustDB:   PRK09330
- BioCyc:   TPAL243276:TP_0390-MONOMER
- GO:   GO:0005737
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008
- Gene3D:   G3DSA:3.30.1330.20
- Gene3D:   G3DSA:3.40.50.1440
- PRINTS:   PR00423
- SMART:   SM00864
- SMART:   SM00865
- TIGRFAMs:   TIGR00065

Pfam domain/function: PF00091 Tubulin; SSF55307 Tub_FtsZ_C; SSF52490 Tubulin_FtsZ

EC number: NA

Molecular weight: Translated: 43840; Mature: 43840

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01134 FTSZ_1; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNIELAPSGEEFTLSPTVIKVIGAGGGGSNAVNRMMSCGLQCVEFIAANTDVQALSYST
CCEEEECCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
APKKLAIGTKVTRGLGAGGDPEIGEKAAMEDAEAIASALQGANMVFITAGMGGGTGTGAA
CCCEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
PVIAKIARELGALTVAVVTKPFRFEGRAKMMLAERGIEKLRTHSDTVIVIPNQNLLSVVD
HHHHHHHHHHCCEEEEEEECCCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHH
KRCPIKETYLVADDLLRKSVQSISDLITLPGEVNLDFMDVKNTMEGQGYALIGVGEGEGE
HCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCC
NRAVDAATAAINNPLLEETRIEGATRLLVAVRGSENLSMGEVDGVMSVVAKTIDPDAIII
CCCHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEE
HGTSIDASMQDRVRVTVIATGVPQASISIAGDTHSSQKIKTSSYGAVSTGVYISSDEWNR
ECCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCEEECCCCCCEEECEEEECCCCCH
AKSSKQPNLPGLATRNSAVQETRMEKNGVKGHTFGVPLPSVNEDLDEPTFLRNRNKGL
HHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MMNIELAPSGEEFTLSPTVIKVIGAGGGGSNAVNRMMSCGLQCVEFIAANTDVQALSYST
CCEEEECCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
APKKLAIGTKVTRGLGAGGDPEIGEKAAMEDAEAIASALQGANMVFITAGMGGGTGTGAA
CCCEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
PVIAKIARELGALTVAVVTKPFRFEGRAKMMLAERGIEKLRTHSDTVIVIPNQNLLSVVD
HHHHHHHHHHCCEEEEEEECCCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHH
KRCPIKETYLVADDLLRKSVQSISDLITLPGEVNLDFMDVKNTMEGQGYALIGVGEGEGE
HCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCC
NRAVDAATAAINNPLLEETRIEGATRLLVAVRGSENLSMGEVDGVMSVVAKTIDPDAIII
CCCHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEE
HGTSIDASMQDRVRVTVIATGVPQASISIAGDTHSSQKIKTSSYGAVSTGVYISSDEWNR
ECCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCEEECCCCCCEEECEEEECCCCCH
AKSSKQPNLPGLATRNSAVQETRMEKNGVKGHTFGVPLPSVNEDLDEPTFLRNRNKGL
HHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876