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The map label for this gene is lldD [C]

Identifier: 189025525

GI number: 189025525

Start: 305865

End: 306746

Strand: Direct

Name: lldD [C]

Synonym: TPASS_0291

Alternate gene names: 189025525

Gene position: 305865-306746 (Clockwise)

Preceding gene: 189025524

Following gene: 189025526

Centisome position: 26.84

GC content: 50.68

Gene sequence:

>882_bases
ATGGTGCGTTCTGCGCGTTCAGAGTACAAGTGTCGCCTGTGTGCCCGTTGTGATGGATACGGGTGTCGTGGTCAGTTACC
AGGGATGGGGGGTGTTTTTAACAGTGCGAATTTTATCGCGAACTGCCTTGCATGGAAAAAATATGTTCCGCAAAGGCATG
AACTACCGGTCGTGCGTCTTGCGCCTATGACGGGTGCAGTTGAAAACGTCGGATATCCTGACGAGGTCTCGTTTTATTAT
CGGCTCATCGAAGCGGTGTCCGGAACGGGTGTCCTGTTGAGTGTGGGAGATGGTTGTCCGGACATCAAACTGCAGTCGGG
TATTGCTGCGTTGCGTTCCTTCAAAAAGAAGGCTGCAGTGTTTATCAAACCGTATGTGAACAAAAAAATTTTTGAACGTA
TCGAGTGGGGTCGGGACGTTGCGGAGTTTGTGGGTGTGGATATCGATGCGTACCATATTGTGACCATGAGAGATAAAGTG
CAGTTAGAGAAAAAGACTCCTACGCACCTTCGTGCAGTCAGACGTTTTGCAAAACTTCCTATCGTGGTGAAAGGAATTTT
TGCGCCGCGCGATGTCGAATTAGTCAGAGAGTTGAAACCGGATGTCGCTATCGTATCAAATCATGGAGGCAGGGTTGAAA
CTGCGCGCGGAAGCACAGCGGACTTTCTTTTTGAATACGGTGGAGAGTTAGCGCGCTGTGCCGGTGAAGTGTGGGTAGAC
GGTGGTATTCGCAGTTATGCGCATTTGTGCGCAGCACGGGAGTTGGGTGCGCAGCAGGTGCTGATAGGGCGTCCTTTTAT
CACAGCTCTTCTCAAAGGAGGAAAGGGTGGGGTGCAACTTCTCGTGCGGAATATGACGGATAGGTCCGTTCGGTGTGTAT
GA

Upstream 100 bases:

>100_bases
TGCCGAATCTAATGATGATGCAGGTTTTGCACAGGCTTTGAAGCGCTATGGGGTGGTAGAGTAAAGAGGGCAGTGCTTTT
TTAGGGAAAAGGAAGATCGC

Downstream 100 bases:

>100_bases
TGGGAAGTGTGTTTTCTAGGAAGGGAATGCTGTGTGTTCTTGCAGTCTGGTGCGCGGCAAGTGCGGCGTACCCTCTGCGC
TTGCGCTACAAGTTTCGTAA

Product: hypothetical protein

Products: Menaquinol 8; Pyruvate [C]

Alternate protein names: Dehydrogenase; FMN-Dependent Family Dehydrogenase; Dehydrogenase FMN-Dependent Family; Dehydrogenase FMN-Dependent; FMN-Dependent Dehydrogenase Domain Protein; L-Lactate Dehydrogenase; Oxidase Or Carboxylase; FMN-Dependent Dehydrogenase; Fmn-Dependent Alpha-Hydroxy Acid Dehydrogenase; Glycolate Oxidase

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MVRSARSEYKCRLCARCDGYGCRGQLPGMGGVFNSANFIANCLAWKKYVPQRHELPVVRLAPMTGAVENVGYPDEVSFYY
RLIEAVSGTGVLLSVGDGCPDIKLQSGIAALRSFKKKAAVFIKPYVNKKIFERIEWGRDVAEFVGVDIDAYHIVTMRDKV
QLEKKTPTHLRAVRRFAKLPIVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELARCAGEVWVD
GGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTDRSVRCV

Sequences:

>Translated_293_residues
MVRSARSEYKCRLCARCDGYGCRGQLPGMGGVFNSANFIANCLAWKKYVPQRHELPVVRLAPMTGAVENVGYPDEVSFYY
RLIEAVSGTGVLLSVGDGCPDIKLQSGIAALRSFKKKAAVFIKPYVNKKIFERIEWGRDVAEFVGVDIDAYHIVTMRDKV
QLEKKTPTHLRAVRRFAKLPIVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELARCAGEVWVD
GGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTDRSVRCV
>Mature_293_residues
MVRSARSEYKCRLCARCDGYGCRGQLPGMGGVFNSANFIANCLAWKKYVPQRHELPVVRLAPMTGAVENVGYPDEVSFYY
RLIEAVSGTGVLLSVGDGCPDIKLQSGIAALRSFKKKAAVFIKPYVNKKIFERIEWGRDVAEFVGVDIDAYHIVTMRDKV
QLEKKTPTHLRAVRRFAKLPIVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELARCAGEVWVD
GGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTDRSVRCV

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.2.3 [C]

Molecular weight: Translated: 32306; Mature: 32306

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSARSEYKCRLCARCDGYGCRGQLPGMGGVFNSANFIANCLAWKKYVPQRHELPVVRL
CCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
APMTGAVENVGYPDEVSFYYRLIEAVSGTGVLLSVGDGCPDIKLQSGIAALRSFKKKAAV
CCCCCCHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEE
FIKPYVNKKIFERIEWGRDVAEFVGVDIDAYHIVTMRDKVQLEKKTPTHLRAVRRFAKLP
EEEHHHCHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHCC
IVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELARCAGEVWVD
EEEEECCCCCHHHHHHHCCCCEEEEECCCCEEEECCCCHHHHHHHHCCHHHHHHHHHEEC
GGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTDRSVRCV
CCHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCHHHHEECCCCCCEECC
>Mature Secondary Structure
MVRSARSEYKCRLCARCDGYGCRGQLPGMGGVFNSANFIANCLAWKKYVPQRHELPVVRL
CCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
APMTGAVENVGYPDEVSFYYRLIEAVSGTGVLLSVGDGCPDIKLQSGIAALRSFKKKAAV
CCCCCCHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEE
FIKPYVNKKIFERIEWGRDVAEFVGVDIDAYHIVTMRDKVQLEKKTPTHLRAVRRFAKLP
EEEHHHCHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHCC
IVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELARCAGEVWVD
EEEEECCCCCHHHHHHHCCCCEEEEECCCCEEEECCCCHHHHHHHHCCHHHHHHHHHEEC
GGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTDRSVRCV
CCHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCHHHHEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN; Heme [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.4 {L-lactate}} [C]

Substrates: L-Lactate; Menaquinone 8 [C]

Specific reaction: L-Lactate + Menaquinone 8 --> Menaquinol 8 + Pyruvate [C]

General reaction: Redox reaction [C]

Inhibitor: Ethanenitronate substrate, [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA