Click here to switch to the map view.

The map label for this gene is hup

Identifier: 189025485

GI number: 189025485

Start: 264112

End: 264429

Strand: Direct

Name: hup

Synonym: TPASS_0251

Alternate gene names: 189025485

Gene position: 264112-264429 (Clockwise)

Preceding gene: 189025484

Following gene: 189025486

Centisome position: 23.18

GC content: 54.72

Gene sequence:

>318_bases
GTGAAGAGAGTTAGGAGAACGCGGTCTTTCGTTGTCGATGCACTTTGTGACGAGGTGGATTTGAGCCGTCGCCATGTCGC
GAGGGTTGTTGATAGCTTTGTCTCTGTGGTAACCGCTGCATTGGAACGGGGGGAGACAGTCGAGCTGAGGGATTTTGGGG
TGTTTGAGTCTCGCGTGCGTAAGGCTTCCGTCGGGAAGAGCATAAAGACAGGGGAGGTGGTCTCTATTCCAAGTCATTGT
GTGGTAGTGTTCCGCCCCAGCAAGCGTTTAAAGAGTGCGGTGCGGGGATATCGTTCGGGGGAGGTTGGTGCGGATTGA

Upstream 100 bases:

>100_bases
CGCCAGAAGTCCCGAATGTGTAGACTGTACAACGGTGTGTTCTCTTCACCCGAGGTGGTGCGCGTTTGAGGCGGCTGTTT
GCCCGCGTGTGTTTCTTGTC

Downstream 100 bases:

>100_bases
GGAATGGTGTCGTTCCCGTCTGGGCGAGTTTTTGTTGTTTGTTCTGGCGGTTTCCCTGTTCGCGCTCTCTCACCCTAACC
CTCTGCTTCCCAGAGGGTGT

Product: DNA-binding protein II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MKRVRRTRSFVVDALCDEVDLSRRHVARVVDSFVSVVTAALERGETVELRDFGVFESRVRKASVGKSIKTGEVVSIPSHC
VVVFRPSKRLKSAVRGYRSGEVGAD

Sequences:

>Translated_105_residues
MKRVRRTRSFVVDALCDEVDLSRRHVARVVDSFVSVVTAALERGETVELRDFGVFESRVRKASVGKSIKTGEVVSIPSHC
VVVFRPSKRLKSAVRGYRSGEVGAD
>Mature_105_residues
MKRVRRTRSFVVDALCDEVDLSRRHVARVVDSFVSVVTAALERGETVELRDFGVFESRVRKASVGKSIKTGEVVSIPSHC
VVVFRPSKRLKSAVRGYRSGEVGAD

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=88, Percent_Identity=38.6363636363636, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DBH_TREPA (O83278)

Other databases:

- EMBL:   AE000520
- PIR:   F71348
- RefSeq:   NP_218692.1
- ProteinModelPortal:   O83278
- SMR:   O83278
- IntAct:   O83278
- GeneID:   2611679
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0251
- NMPDR:   fig|243276.1.peg.251
- TIGR:   TP_0251
- HOGENOM:   HBG705085
- OMA:   ISAMAEK
- ProtClustDB:   CLSK2300170
- BioCyc:   TPAL243276:TP_0251-MONOMER
- InterPro:   IPR000119
- InterPro:   IPR010992
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11650; Mature: 11650

Theoretical pI: Translated: 11.00; Mature: 11.00

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVRRTRSFVVDALCDEVDLSRRHVARVVDSFVSVVTAALERGETVELRDFGVFESRVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCHHHHHHHH
KASVGKSIKTGEVVSIPSHCVVVFRPSKRLKSAVRGYRSGEVGAD
HHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKRVRRTRSFVVDALCDEVDLSRRHVARVVDSFVSVVTAALERGETVELRDFGVFESRVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCHHHHHHHH
KASVGKSIKTGEVVSIPSHCVVVFRPSKRLKSAVRGYRSGEVGAD
HHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876