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The map label for this gene is rpoC

Identifier: 189025475

GI number: 189025475

Start: 250317

End: 254567

Strand: Direct

Name: rpoC

Synonym: TPASS_0242

Alternate gene names: 189025475

Gene position: 250317-254567 (Clockwise)

Preceding gene: 189025474

Following gene: 189025476

Centisome position: 21.97

GC content: 50.6

Gene sequence:

>4251_bases
ATGAAGGATATCCGGGATTTTGACAGTTTACAGATAAAGCTTGCCTCCCCTGATACCATTCGGGCATGGTCCTATGGAGA
GGTGAAAAAGCCTGAGACAATTAATTACCGCACGTTGCGTCCTGAACGTGAAGGGCTTTTTTGTGAACGCATTTTTGGTA
CTACAAAGGAATGGGAATGCTTTTGTGGAAAGTTTAAGTCAATTCGGTACCGGGGTGTTATCTGCGATCGGTGCGGGGTG
GAGGTAACGCATTTCAAGGTTCGCAGGGAGCGCATGGGGCATATTGAGCTTGCAACGCCTGTTTCTCATATTTGGTACTA
CCGTTGTGTACCAAGTAGAATGGGTTTGTTACTCGATCTACAGGTGATCGCACTGCGTTCTGTTTTGTACTATGAGAAGT
ACATAGTTATAGAGCCGGGCGACACCGATTTAAAAAAGAATCAGTTGCTCACTGAAACTGAGTACAATGACGCGCAGGAG
CGCTACGGTGGCGGCTTTACGGCGGGAATGGGAGCGGAGGCTATCCGTACCCTTTTGCAAAACCTTGACCTTGACGCGCT
TGTTGCACAGTTGCGTGAGAAGATGATGGAGAAGGGTGCGAAAAGCGACAAACGCTTGCTGCGTCGCATAGAGATCGTAG
AAAACTTTCGGGTGTCGGGAAATAAGCCGGAATGGATGATTTTGAGCGTTATCCCGGTGATCCCGCCTGATTTGCGTCCT
ATGGTGCAGCTCGACGGAGGGCGTTTTGCTACCTCAGATCTCAATGACCTGTATCGGCGTGTGATCCACCGCAATAGCCG
TTTGATTCGGCTCATGGAACTGAAGGCGCCGGATATCATCATTCGGAACGAAAAGCGCATGTTGCAAGAGGCAGTGGACG
CGCTTTTTGATAATTCTAAGCGCAAGCCCGCGATTAAAGGTGCGTCAAACCGGCCGCTTAAGTCTATTTCTGACATGCTC
AAGGGGAAGCAAGGGCGTTTTCGCCAGAATCTTTTGGGCAAGCGGGTCGACTATTCCGGGCGTTCGGTTATCGTAGTGGG
GCCTGAACTTAAGTTGTGGCAGTGCGGGTTGCCTACAAAAATGGCGCTTGAGCTGTTTAAGCCCTTTATTATGAAAAAGC
TGGTTGAGAAAGAAATTGTCTCGAACATCAAAAAGGCAAAGATGCTCGTGGAACAAGAGTCGCCGAAGGTATTTTCGGTG
TTGGATGAAGTGGTAAAAGAGCATCCAGTTATGCTTAATCGGGCGCCGACATTGCATCGATTGGGCATTCAGGCTTTTGA
GCCGGTGTTGGTGGAGGGGAAGGCGATTCGTCTTCATCCGCTTGTGTGTAAACCTTTTAATGCTGATTTTGATGGGGATC
AAATGGCGGTGCATGTGCCGCTGACGCAGGCGGCACAGATGGAGTGTTGGACGCTCATGTTGTCGAATCGCAATTTGCTT
GACCCTGCAAATGGGCGCACGATTGTGTATCCATCTCAGGACATGGTTCTGGGTTTGTATTATCTGACAAAGGAACGCTC
TCTGCCGGAGGGTGCTCGTCCTCGCCGTTTTTCCTCGGTGGAGGAGGTAATGATGGCTGCGGAAAAGGGGGTAATCGGCT
GGCAGGATCAGATTCAAGTGCGATATCACAAATGTGATGGTCAGCTTGTGGTCACTACCGCAGGAAGACTTGTGTTGAAT
GAGGAAGTTCCCGCAGAGATTCCTTTTGTCAACGAAACGCTTGATGACAAACGCATCAGGAAATTAATTGAGCGGGTGTT
CAAGCGTCAGGATTCTTGGCTTGCGGTGCAGATGCTCGATGCACTGAAAACTATCGGTTATACCTACGCGACCTTCTTTG
GTGCAACGCTCAGTATGGACGACATCATCGTGCCTGAGCAGAAGGTGCAGATGCTCGAAAAGGCGAACAAGGAAGTGCTA
GCGATTGCGAGTCAATACCGCGGGGGGCACATCACGCAAGAGGAGCGTTATAATCGCGTCGTTGAGGTGTGGTCTAAAAC
AAGTGAGGAGCTCACTTCGCTCATGATGGAAACACTTGAGCGCGACAAGGATGGATTTAATACCATTTACATGATGGCTA
CCTCAGGTGCGCGCGGGAGTCGCAATCAAATCCGCCAACTGGCGGGAATGCGTGGCTTAATGGCAAAGCCGAGTGGGGAT
ATCATCGAATTGCCTATTCGTTCTAATTTTAAAGAGGGACTCAATGTCATTGAGTTTTTTATTTCTACCAACGGTGCACG
CAAAGGGCTCGCAGACACTGCGCTAAAGACCGCTGATGCGGGGTATTTGACACGTCGTCTGGTTGATATCGCGCAAGATG
TGGTGGTGAACGAGGAGGACTGTGGTACCATCAATGGCATTGAATATCGCGCGGTGAAGTCCGGCGATGAGATTATTGAA
TCGCTTGCTGAGCGCATCGTAGGAAAGTATACACTTGAACGTGTAGAACACCCCATCACCCATGAACTGCTGCTCGATGT
GAACGAATACATCGACGATGAGCGTGCAGAAAAGGTGGAAGAAGCGGGCGTGGAGTCAGTGAAGTTGCGCACCGTGCTCA
CGTGCGAATCTAAGCGAGGAGTGTGTGTGTGCTGCTACGGGCGGAATCTTGCACGCAACAAAATTGTAGAAATTGGGGAG
GCGGTTGGGATTGTAGCCGCTCAGTCCATTGGTCAGCCGGGTACGCAGCTGACAATGCGCACGTTCCATGTTGGGGGTAC
GGCAAGCAGTACTACGGAAGAGAACCGCATCACGTTTAAGTATCCCATACTGGTAAAGAGTATTGAGGGGGTGCATGTGA
AAATGGAGGATGGCTCTCAGCTGTTCACGCGTCGGGGGACGCTCTTTTTTCACAAAACTCTGGCAGAGTATCAGCTTCAA
GAGGGTGACAGCGTGCAGGTGCGTGACCGCGCGCGGGTGCTAAAGGATGAGGTTCTCTACCACACCACCGATGGGCAGAC
GGTGTACGCTTCGGTGAGTGGTTTTGCGCGTATAATCGATCGAACCGTGTACCTGGTAGGGCCTGAGCAAAAGACGGAAA
TTCGCAATGGTTCTAATGTAGTAATCAAGGCAGACGAGTATGTGCCGCCCGGAAAGACCGTGGCTACGTTTGATCCGTTC
ACTGAACCTATTTTGGCAGAGCAGGATGGCTTTGTGCGGTACGAAGATATTATTTTGGGCTCTACGCTCATCGAAGAGGT
AAATACTGAAACGGGGATGGTGGAGCGCAGGATTACGACGTTGAAAACAGGAATACAGCTTCAACCGCGGGTATTCATCT
CTGATGAGTCGGGGAATGCGCTGGGTTCGTACTACTTGCCAGAGGAAGCGCGCTTGATGGTTGAAGAAGGCGCGCAGGTG
AAGGCGGGTACGGTCATTGTAAAACTGGCAAAAGCAATTCAAAAGACATCGGATATTACGGGGGGGCTGCCGCGTGTTTC
TGAATTATTTGAAGCGCGGCGCCCTAAGAATGCGGCTGTCTTGGCACAGATTTCTGGGGTTGTGTCGTTCAAAGGACTGT
TTAAGGGTAAGCGTATTGTCGTGGTGCGTGACCATTACGGGAAGGAATATAAGCACCTCGTGTCCATGTCGCGTCAGCTT
TTAGTACGTGATGGAGATACGGTTGAGGCAGGCGAACGCTTGTGTGATGGTTGCTTTGATCCCCATGATATCCTGGCAAT
TCTGGGTGAAAATGCTTTGCAAAACTATTTGATGAATGAGATCCGTGACGTGTATCGTGTGCAGGGTGTTTCAATCAATG
ACCAGCACATTGGTTTAGTGGTGCGGCAAATGCTACGAAAGACAGAGGTTGTCTCGGTTGGGGACACGCGTTTTATCTAC
GGGCAACAGGTGGATAAGTACCGTTTTCACGAAGAGAACCGTCGGGTTGAAGCGGAAGGGGGGCAGCCTGCGGTTGCGCG
CCCAATGTTCCAGGGTATAACGAAGGCGGCGTTGAACATAGACTCTTTCATATCTGCGGCATCTTTCCAAGAAACGAACA
AGGTGCTCACCAATGCGGCGATTGCAGGCTCTGTTGATGACTTGTGTGGGTTGAAGGAGAACGTCATTATAGGGCACTTA
ATTCCCGCAGGTACGGGGATGCGGCGTTATCGTCAGGTGAAGCTGTTTGACAAGAACAAGCGGGATCTTGATGTGCAGAT
GGAGGAAGTTATCAGGCGTAGAAAACTTGAAGAGGAGGCGCTTGCCCAGGCAGTTGCGGGTATGGAAGGGGAACCTGAAG
GCGAAGCGTGA

Upstream 100 bases:

>100_bases
CTTTACGATTTACGATGCGAAGGGCAAGCAGATTCCGCTCACTGAGCGCGATGAAGAAATGACGAATAAGATTGGCTCTA
AATTTTAAGGGGTGCAGGGA

Downstream 100 bases:

>100_bases
TGGATTGACCTGGTTTGGCTATTCTGAGTATCCTAGCCGCGTGTGCTGTGTGCGGCAAGGTTTACGGTGTTGAGGATTTT
TTTGGGGAAGTGAGCGAAAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1416; Mature: 1416

Protein sequence:

>1416_residues
MKDIRDFDSLQIKLASPDTIRAWSYGEVKKPETINYRTLRPEREGLFCERIFGTTKEWECFCGKFKSIRYRGVICDRCGV
EVTHFKVRRERMGHIELATPVSHIWYYRCVPSRMGLLLDLQVIALRSVLYYEKYIVIEPGDTDLKKNQLLTETEYNDAQE
RYGGGFTAGMGAEAIRTLLQNLDLDALVAQLREKMMEKGAKSDKRLLRRIEIVENFRVSGNKPEWMILSVIPVIPPDLRP
MVQLDGGRFATSDLNDLYRRVIHRNSRLIRLMELKAPDIIIRNEKRMLQEAVDALFDNSKRKPAIKGASNRPLKSISDML
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLWQCGLPTKMALELFKPFIMKKLVEKEIVSNIKKAKMLVEQESPKVFSV
LDEVVKEHPVMLNRAPTLHRLGIQAFEPVLVEGKAIRLHPLVCKPFNADFDGDQMAVHVPLTQAAQMECWTLMLSNRNLL
DPANGRTIVYPSQDMVLGLYYLTKERSLPEGARPRRFSSVEEVMMAAEKGVIGWQDQIQVRYHKCDGQLVVTTAGRLVLN
EEVPAEIPFVNETLDDKRIRKLIERVFKRQDSWLAVQMLDALKTIGYTYATFFGATLSMDDIIVPEQKVQMLEKANKEVL
AIASQYRGGHITQEERYNRVVEVWSKTSEELTSLMMETLERDKDGFNTIYMMATSGARGSRNQIRQLAGMRGLMAKPSGD
IIELPIRSNFKEGLNVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVNEEDCGTINGIEYRAVKSGDEIIE
SLAERIVGKYTLERVEHPITHELLLDVNEYIDDERAEKVEEAGVESVKLRTVLTCESKRGVCVCCYGRNLARNKIVEIGE
AVGIVAAQSIGQPGTQLTMRTFHVGGTASSTTEENRITFKYPILVKSIEGVHVKMEDGSQLFTRRGTLFFHKTLAEYQLQ
EGDSVQVRDRARVLKDEVLYHTTDGQTVYASVSGFARIIDRTVYLVGPEQKTEIRNGSNVVIKADEYVPPGKTVATFDPF
TEPILAEQDGFVRYEDIILGSTLIEEVNTETGMVERRITTLKTGIQLQPRVFISDESGNALGSYYLPEEARLMVEEGAQV
KAGTVIVKLAKAIQKTSDITGGLPRVSELFEARRPKNAAVLAQISGVVSFKGLFKGKRIVVVRDHYGKEYKHLVSMSRQL
LVRDGDTVEAGERLCDGCFDPHDILAILGENALQNYLMNEIRDVYRVQGVSINDQHIGLVVRQMLRKTEVVSVGDTRFIY
GQQVDKYRFHEENRRVEAEGGQPAVARPMFQGITKAALNIDSFISAASFQETNKVLTNAAIAGSVDDLCGLKENVIIGHL
IPAGTGMRRYRQVKLFDKNKRDLDVQMEEVIRRRKLEEEALAQAVAGMEGEPEGEA

Sequences:

>Translated_1416_residues
MKDIRDFDSLQIKLASPDTIRAWSYGEVKKPETINYRTLRPEREGLFCERIFGTTKEWECFCGKFKSIRYRGVICDRCGV
EVTHFKVRRERMGHIELATPVSHIWYYRCVPSRMGLLLDLQVIALRSVLYYEKYIVIEPGDTDLKKNQLLTETEYNDAQE
RYGGGFTAGMGAEAIRTLLQNLDLDALVAQLREKMMEKGAKSDKRLLRRIEIVENFRVSGNKPEWMILSVIPVIPPDLRP
MVQLDGGRFATSDLNDLYRRVIHRNSRLIRLMELKAPDIIIRNEKRMLQEAVDALFDNSKRKPAIKGASNRPLKSISDML
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLWQCGLPTKMALELFKPFIMKKLVEKEIVSNIKKAKMLVEQESPKVFSV
LDEVVKEHPVMLNRAPTLHRLGIQAFEPVLVEGKAIRLHPLVCKPFNADFDGDQMAVHVPLTQAAQMECWTLMLSNRNLL
DPANGRTIVYPSQDMVLGLYYLTKERSLPEGARPRRFSSVEEVMMAAEKGVIGWQDQIQVRYHKCDGQLVVTTAGRLVLN
EEVPAEIPFVNETLDDKRIRKLIERVFKRQDSWLAVQMLDALKTIGYTYATFFGATLSMDDIIVPEQKVQMLEKANKEVL
AIASQYRGGHITQEERYNRVVEVWSKTSEELTSLMMETLERDKDGFNTIYMMATSGARGSRNQIRQLAGMRGLMAKPSGD
IIELPIRSNFKEGLNVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVNEEDCGTINGIEYRAVKSGDEIIE
SLAERIVGKYTLERVEHPITHELLLDVNEYIDDERAEKVEEAGVESVKLRTVLTCESKRGVCVCCYGRNLARNKIVEIGE
AVGIVAAQSIGQPGTQLTMRTFHVGGTASSTTEENRITFKYPILVKSIEGVHVKMEDGSQLFTRRGTLFFHKTLAEYQLQ
EGDSVQVRDRARVLKDEVLYHTTDGQTVYASVSGFARIIDRTVYLVGPEQKTEIRNGSNVVIKADEYVPPGKTVATFDPF
TEPILAEQDGFVRYEDIILGSTLIEEVNTETGMVERRITTLKTGIQLQPRVFISDESGNALGSYYLPEEARLMVEEGAQV
KAGTVIVKLAKAIQKTSDITGGLPRVSELFEARRPKNAAVLAQISGVVSFKGLFKGKRIVVVRDHYGKEYKHLVSMSRQL
LVRDGDTVEAGERLCDGCFDPHDILAILGENALQNYLMNEIRDVYRVQGVSINDQHIGLVVRQMLRKTEVVSVGDTRFIY
GQQVDKYRFHEENRRVEAEGGQPAVARPMFQGITKAALNIDSFISAASFQETNKVLTNAAIAGSVDDLCGLKENVIIGHL
IPAGTGMRRYRQVKLFDKNKRDLDVQMEEVIRRRKLEEEALAQAVAGMEGEPEGEA
>Mature_1416_residues
MKDIRDFDSLQIKLASPDTIRAWSYGEVKKPETINYRTLRPEREGLFCERIFGTTKEWECFCGKFKSIRYRGVICDRCGV
EVTHFKVRRERMGHIELATPVSHIWYYRCVPSRMGLLLDLQVIALRSVLYYEKYIVIEPGDTDLKKNQLLTETEYNDAQE
RYGGGFTAGMGAEAIRTLLQNLDLDALVAQLREKMMEKGAKSDKRLLRRIEIVENFRVSGNKPEWMILSVIPVIPPDLRP
MVQLDGGRFATSDLNDLYRRVIHRNSRLIRLMELKAPDIIIRNEKRMLQEAVDALFDNSKRKPAIKGASNRPLKSISDML
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLWQCGLPTKMALELFKPFIMKKLVEKEIVSNIKKAKMLVEQESPKVFSV
LDEVVKEHPVMLNRAPTLHRLGIQAFEPVLVEGKAIRLHPLVCKPFNADFDGDQMAVHVPLTQAAQMECWTLMLSNRNLL
DPANGRTIVYPSQDMVLGLYYLTKERSLPEGARPRRFSSVEEVMMAAEKGVIGWQDQIQVRYHKCDGQLVVTTAGRLVLN
EEVPAEIPFVNETLDDKRIRKLIERVFKRQDSWLAVQMLDALKTIGYTYATFFGATLSMDDIIVPEQKVQMLEKANKEVL
AIASQYRGGHITQEERYNRVVEVWSKTSEELTSLMMETLERDKDGFNTIYMMATSGARGSRNQIRQLAGMRGLMAKPSGD
IIELPIRSNFKEGLNVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVNEEDCGTINGIEYRAVKSGDEIIE
SLAERIVGKYTLERVEHPITHELLLDVNEYIDDERAEKVEEAGVESVKLRTVLTCESKRGVCVCCYGRNLARNKIVEIGE
AVGIVAAQSIGQPGTQLTMRTFHVGGTASSTTEENRITFKYPILVKSIEGVHVKMEDGSQLFTRRGTLFFHKTLAEYQLQ
EGDSVQVRDRARVLKDEVLYHTTDGQTVYASVSGFARIIDRTVYLVGPEQKTEIRNGSNVVIKADEYVPPGKTVATFDPF
TEPILAEQDGFVRYEDIILGSTLIEEVNTETGMVERRITTLKTGIQLQPRVFISDESGNALGSYYLPEEARLMVEEGAQV
KAGTVIVKLAKAIQKTSDITGGLPRVSELFEARRPKNAAVLAQISGVVSFKGLFKGKRIVVVRDHYGKEYKHLVSMSRQL
LVRDGDTVEAGERLCDGCFDPHDILAILGENALQNYLMNEIRDVYRVQGVSINDQHIGLVVRQMLRKTEVVSVGDTRFIY
GQQVDKYRFHEENRRVEAEGGQPAVARPMFQGITKAALNIDSFISAASFQETNKVLTNAAIAGSVDDLCGLKENVIIGHL
IPAGTGMRRYRQVKLFDKNKRDLDVQMEEVIRRRKLEEEALAQAVAGMEGEPEGEA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=563, Percent_Identity=27.1758436944938, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI39725938, Length=322, Percent_Identity=31.055900621118, Blast_Score=124, Evalue=9e-28,
Organism=Homo sapiens, GI103471997, Length=256, Percent_Identity=30.078125, Blast_Score=94, Evalue=1e-18,
Organism=Escherichia coli, GI2367335, Length=1401, Percent_Identity=49.7501784439686, Blast_Score=1319, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=566, Percent_Identity=26.5017667844523, Blast_Score=137, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25145495, Length=344, Percent_Identity=30.2325581395349, Blast_Score=136, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320061, Length=885, Percent_Identity=24.8587570621469, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=327, Percent_Identity=30.2752293577982, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17530899, Length=570, Percent_Identity=26.3157894736842, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360912, Length=312, Percent_Identity=30.7692307692308, Blast_Score=130, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17647875, Length=328, Percent_Identity=25.3048780487805, Blast_Score=96, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_TREPA (O83270)

Other databases:

- EMBL:   AE000520
- PIR:   D71350
- RefSeq:   NP_218682.1
- ProteinModelPortal:   O83270
- SMR:   O83270
- GeneID:   2611178
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0242
- NMPDR:   fig|243276.1.peg.241
- TIGR:   TP_0242
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- BioCyc:   TPAL243276:TP_0242-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 159793; Mature: 159793

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIRDFDSLQIKLASPDTIRAWSYGEVKKPETINYRTLRPEREGLFCERIFGTTKEWEC
CCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCHHHH
FCGKFKSIRYRGVICDRCGVEVTHFKVRRERMGHIELATPVSHIWYYRCVPSRMGLLLDL
HHHHHHCEEEEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHHEEEECHHHCCHHHHH
QVIALRSVLYYEKYIVIEPGDTDLKKNQLLTETEYNDAQERYGGGFTAGMGAEAIRTLLQ
HHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHH
NLDLDALVAQLREKMMEKGAKSDKRLLRRIEIVENFRVSGNKPEWMILSVIPVIPPDLRP
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
MVQLDGGRFATSDLNDLYRRVIHRNSRLIRLMELKAPDIIIRNEKRMLQEAVDALFDNSK
EEEECCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCC
RKPAIKGASNRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLWQCGLPTK
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCHH
MALELFKPFIMKKLVEKEIVSNIKKAKMLVEQESPKVFSVLDEVVKEHPVMLNRAPTLHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCHHH
LGIQAFEPVLVEGKAIRLHPLVCKPFNADFDGDQMAVHVPLTQAAQMECWTLMLSNRNLL
HCHHHHCCEEECCCEEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHEEEEEECCCCCC
DPANGRTIVYPSQDMVLGLYYLTKERSLPEGARPRRFSSVEEVMMAAEKGVIGWQDQIQV
CCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEE
RYHKCDGQLVVTTAGRLVLNEEVPAEIPFVNETLDDKRIRKLIERVFKRQDSWLAVQMLD
EEEECCCEEEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
ALKTIGYTYATFFGATLSMDDIIVPEQKVQMLEKANKEVLAIASQYRGGHITQEERYNRV
HHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHCCHHEEEHHHHCCCCCCCHHHHHHHH
VEVWSKTSEELTSLMMETLERDKDGFNTIYMMATSGARGSRNQIRQLAGMRGLMAKPSGD
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
IIELPIRSNFKEGLNVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVNEED
EEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
CGTINGIEYRAVKSGDEIIESLAERIVGKYTLERVEHPITHELLLDVNEYIDDERAEKVE
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
EAGVESVKLRTVLTCESKRGVCVCCYGRNLARNKIVEIGEAVGIVAAQSIGQPGTQLTMR
HCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
TFHVGGTASSTTEENRITFKYPILVKSIEGVHVKMEDGSQLFTRRGTLFFHKTLAEYQLQ
EEEECCCCCCCCCCCEEEEEECEEEEECCCEEEEECCCCHHHHHCCCCEEHHHHHHHHHC
EGDSVQVRDRARVLKDEVLYHTTDGQTVYASVSGFARIIDRTVYLVGPEQKTEIRNGSNV
CCCCEEHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHCEEEEECCCHHHHCCCCCEE
VIKADEYVPPGKTVATFDPFTEPILAEQDGFVRYEDIILGSTLIEEVNTETGMVERRITT
EEEECCCCCCCCEEEECCCCCCCHHCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
LKTGIQLQPRVFISDESGNALGSYYLPEEARLMVEEGAQVKAGTVIVKLAKAIQKTSDIT
HHCCCEECCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCC
GGLPRVSELFEARRPKNAAVLAQISGVVSFKGLFKGKRIVVVRDHYGKEYKHLVSMSRQL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
LVRDGDTVEAGERLCDGCFDPHDILAILGENALQNYLMNEIRDVYRVQGVSINDQHIGLV
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VRQMLRKTEVVSVGDTRFIYGQQVDKYRFHEENRRVEAEGGQPAVARPMFQGITKAALNI
HHHHHHHCCEEECCCCEEEECCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHH
DSFISAASFQETNKVLTNAAIAGSVDDLCGLKENVIIGHLIPAGTGMRRYRQVKLFDKNK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCHHHHHEEEEECCCC
RDLDVQMEEVIRRRKLEEEALAQAVAGMEGEPEGEA
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKDIRDFDSLQIKLASPDTIRAWSYGEVKKPETINYRTLRPEREGLFCERIFGTTKEWEC
CCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCHHHH
FCGKFKSIRYRGVICDRCGVEVTHFKVRRERMGHIELATPVSHIWYYRCVPSRMGLLLDL
HHHHHHCEEEEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHHEEEECHHHCCHHHHH
QVIALRSVLYYEKYIVIEPGDTDLKKNQLLTETEYNDAQERYGGGFTAGMGAEAIRTLLQ
HHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHH
NLDLDALVAQLREKMMEKGAKSDKRLLRRIEIVENFRVSGNKPEWMILSVIPVIPPDLRP
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
MVQLDGGRFATSDLNDLYRRVIHRNSRLIRLMELKAPDIIIRNEKRMLQEAVDALFDNSK
EEEECCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCC
RKPAIKGASNRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLWQCGLPTK
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCHH
MALELFKPFIMKKLVEKEIVSNIKKAKMLVEQESPKVFSVLDEVVKEHPVMLNRAPTLHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCHHH
LGIQAFEPVLVEGKAIRLHPLVCKPFNADFDGDQMAVHVPLTQAAQMECWTLMLSNRNLL
HCHHHHCCEEECCCEEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHEEEEEECCCCCC
DPANGRTIVYPSQDMVLGLYYLTKERSLPEGARPRRFSSVEEVMMAAEKGVIGWQDQIQV
CCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEE
RYHKCDGQLVVTTAGRLVLNEEVPAEIPFVNETLDDKRIRKLIERVFKRQDSWLAVQMLD
EEEECCCEEEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
ALKTIGYTYATFFGATLSMDDIIVPEQKVQMLEKANKEVLAIASQYRGGHITQEERYNRV
HHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHCCHHEEEHHHHCCCCCCCHHHHHHHH
VEVWSKTSEELTSLMMETLERDKDGFNTIYMMATSGARGSRNQIRQLAGMRGLMAKPSGD
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
IIELPIRSNFKEGLNVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVNEED
EEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
CGTINGIEYRAVKSGDEIIESLAERIVGKYTLERVEHPITHELLLDVNEYIDDERAEKVE
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
EAGVESVKLRTVLTCESKRGVCVCCYGRNLARNKIVEIGEAVGIVAAQSIGQPGTQLTMR
HCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
TFHVGGTASSTTEENRITFKYPILVKSIEGVHVKMEDGSQLFTRRGTLFFHKTLAEYQLQ
EEEECCCCCCCCCCCEEEEEECEEEEECCCEEEEECCCCHHHHHCCCCEEHHHHHHHHHC
EGDSVQVRDRARVLKDEVLYHTTDGQTVYASVSGFARIIDRTVYLVGPEQKTEIRNGSNV
CCCCEEHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHCEEEEECCCHHHHCCCCCEE
VIKADEYVPPGKTVATFDPFTEPILAEQDGFVRYEDIILGSTLIEEVNTETGMVERRITT
EEEECCCCCCCCEEEECCCCCCCHHCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
LKTGIQLQPRVFISDESGNALGSYYLPEEARLMVEEGAQVKAGTVIVKLAKAIQKTSDIT
HHCCCEECCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCC
GGLPRVSELFEARRPKNAAVLAQISGVVSFKGLFKGKRIVVVRDHYGKEYKHLVSMSRQL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
LVRDGDTVEAGERLCDGCFDPHDILAILGENALQNYLMNEIRDVYRVQGVSINDQHIGLV
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VRQMLRKTEVVSVGDTRFIYGQQVDKYRFHEENRRVEAEGGQPAVARPMFQGITKAALNI
HHHHHHHCCEEECCCCEEEECCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHH
DSFISAASFQETNKVLTNAAIAGSVDDLCGLKENVIIGHLIPAGTGMRRYRQVKLFDKNK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCHHHHHEEEEECCCC
RDLDVQMEEVIRRRKLEEEALAQAVAGMEGEPEGEA
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876