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The map label for this gene is rpoB

Identifier: 189025474

GI number: 189025474

Start: 246768

End: 250304

Strand: Direct

Name: rpoB

Synonym: TPASS_0241

Alternate gene names: 189025474

Gene position: 246768-250304 (Clockwise)

Preceding gene: 189025473

Following gene: 189025475

Centisome position: 21.66

GC content: 49.93

Gene sequence:

>3537_bases
ATGTCAGCACGAGTTTGCAAAACACACAGAGTGTACGTGGGAAGGGATGTCAGGAATTTTATGGACATCCCGGATCTCAT
CGAAATCCAGCTTCGATCTTACGACACCTTTCTGCATGGGGCCCGGAATACACCGTCCGGCGCCGACACCCTTATCTCCG
GTACTAGAGAGGAGCTCGGCCTCGAAGACGTGTTCAAGACTACCTTTCCTATCGAGAGCTCTACGGGGGACATGACGCTC
GAGTACCAATCATACTCCCTTGATGAGAAAAACATCAAGTTCTCCGAGGCGGAGTGTAAACAAAAGGGTTTGACGTACGC
CATTCCGCTGAAGGCGCTTGTTGATTTACGTTTCAATAATACGGGGGAGATTAGGCGCAAAGACATTTATATGGGAGATA
TCCCCAAGATGACTGAACGCGGCACCTTTATCATCAACGGTGCGGAGCGTGTGGTGGTATCCCAGATCCATCGTTCCCCT
GGTGTTGTCTTTTCTCATGAGAAGGACAAGGAAGGACGGGAGGTATTCTCCAGCCGCATTATTCCGTACCGGGGAAGCTG
GCTTGAATTTGAAATTGATCAGAAAAAAGATCTCATCTATGCAAAGCTTGATAAAAAGAGACGTATCCTAGGCACCGTGT
TTTTGCGTGCGTTGCACTACGAAACGCGTGAGCAGATCATCGAGGCCTTTTACGCCATAGAAAAGACGCCTGTTTGTCAG
GATCGTGCGGAGTACGAGCTGCTCACAGGTAAGATCCTAGCACGATCGGTGACGGTGGAAAATGAGCAGGGTGAAACCCG
GGTGTTGTACAAAGCAGGAGAGAAAATCCATCCCCATGTCATCGATGATCTGCTGCAAAACGGCATATGTGAGGTCTACA
TTATTAACCTTGAAGCGGAAGGTTCGTTGCGTTCTGCGGTCGTTATCAATTGTCTTGAACGAGAGGAAATGAAGTTCTCT
AAGTCGGGTGCACAGGACGAGCTTTCGCGTGAAGAGGCACTGTGTATTGTATACTCAGCGCTAAGACCAAGCGATCCTAT
GACCATGGACGCGGCGGAAAAAGATTTGCAGACAATGTTTTTCTCCCCACGTCGCTATGATTTAGGGCGGGTGGGGCGCT
ACAAGCTGAACAAGAAATTTCGCTCTGACTCGCCGACTACTGAGTGCACGCTCACCCTCGATGATATCGTAAATACCATG
AAATTTCTCATCAGAATGTATAGCGGTGATGCACAGGAAGATGATATCGATCACCTGGGCAACCGTCGTATTCGTTCGGT
GGGGGAATTAATGACCAATACGTTAAAAACGGCCTTTTTGCGCATGGAACGTATTGCGAAGGAGCGTATGAGTTCTAAGG
AAACGGAAACGATCAAGCCGCAGGATCTCATTTCCATAAAACCTATCATGGCTGCGATTAAGGAGTTCTTTGGTGCAAGT
CAGCTTTCTCAGTTCATGGATCAGGTCAATCCGCTGGCGGAGTTGACACACAAGCGGCGTTTGAACGCACTTGGTCCTGG
TGGACTTTCAAGGGAGCGTGCTGGGTTTGAGGTACGCGATGTGCACTACACGCACTACGGTCGGATGTGTCCCATTGAGA
CCCCCGAAGGACCAAATATCGGTTTAATTGTTTCTATGGCCAATTACGCACGCGTTAACGGGTATGGGTTCTTGGAGGTG
CCGTATGTACGGGTGCGTGACGGAGTTGTTACGAAAGAGATTGAGTACCTGGATGCTATGGACGAGGATCGCTACTACAT
TGGGCAGGATTCTACGGCGGTAGGACCGGACGGGGTCATCCGTGTAGATCATGTCTCTTGTCGGCACCGGGGGGATTACA
GTACGCGTAGTCCTAAGGATATCCAGTATATGGATGTTTCCCCCAAGCAGATAATTTCTGTTTCTGCTTCTCTCATACCG
TTTCTTGAGCATGATGATGCTAACCGTGCGTTAATGGGGTCGAACATGCAACGGCAGGGAGTGCCGCTTATTTTTCCTGA
ACCCCCGCGCGTGGGTACAGGCATGGAAGAGAAGTGTGCATATGACTCTGGAGTGCTGGTGAAGGCAAAGCAAGACGGAA
CGGTTGCCTACGTTTCCTCAGAGAAGATAGTGGTTTGTTCCGCCGCGGCGTCTGGGGAAGAGCAGGAGGTCGTGTATCCG
TTACTTAAGTATCAGCGGACAAATCAGGATACCTGTTACCACCAGCGGCCAATAGTGCACGTGGGAGATCGGGTACAGGT
AGGAGATGCGCTTGCAGACGGTCCTGCAACGTATCGAGGGGAGCTTGCGCTTGGCAGAAACATTCTAGTTGGTTTTGTGC
CGTGGAACGGTTACAACTACGAGGATGCCATTTTGATTTCTCACCGGGTGGTAAAGGAGGATATGTTCACCTCGGTTCAC
ATCAAAGAATTTTCTACTGAGGTGCGTGAAACCAAGCTGGGTTCTGAACGAATGACGAATGATATCCCGAATAAGTCTGA
GAAGAATCTGGATAATTTGGATGCAGAGGGGATCATTCGTATTGGGTCAAAGGTGCGTGCGGGAGACGTGCTTATCGGAA
AGATTACGCCAAAAAGCGAGTCTGAGACGACGCCAGAGTTTAGGCTGCTGAATTCTATTTTTGGGGAGAAGGCGAAGGAA
GTGCGTGATTCTTCTCTACGTGTGCCGCATGGAGTTGAGGGTACAGTCATTGACGTGCAGCGACTCAGGCGTTCGGAGGG
AGATGATTTAAACCCCGGGGTGTCAGAGGTGGTGAAGGTTCTTATCGCTACCAAGCGTAAGCTGCGTGAAGGGGATAAAA
TGGCCGGTCGCCACGGTAACAAGGGTATCGTTGCGCGCATCCTTCCTGAAGAAGACATGCCGTATCTGGATGATGGTACC
CCGCTTGATGTCTGTTTGAACCCGCTCGGTGTACCTTCTCGTATGAACATAGGACAGATTCTTGAATCTGAATTGGGACT
TGCGGGGTTGCGGCTTGACGAATGGTATGAGTCTCCTGTCTTTCAATCTCCAAGCAACGAGCAGATTGGGGAAAAGTTGA
TGCAGGCAGGTTTTCCGACTAATTCAAAAGTGATGCTGCGTGACGGACGCACGGGGGATTATTTTCAAAACCCTGTATTT
GTGGGGGTTATTTACTTTATGAAGCTTGCGCATCTAGTGGATGACAAAATGCACGCCCGCTCTACAGGTCCATATTCGCT
TGTGACGCAGCAACCCTTAGGGGGTAAAGCGCAGTTTGGAGGGCAGCGTCTCGGGGAAATGGAGGTGTGGGCGCTTGAAG
CCTACGGCGCGGCGAATACCCTGCAGGAGTTGCTAACGATTAAATCGGATGATATGCACGGGCGTTCTAAAATTTATGAG
GCAATTGTAAAAGGGGAGGCTTCGTCTCCTACCGGTATTCCTGAATCTTTTAACGTGTTGGTGCAGGAGCTGCGGGGACT
TGCGCTCGACTTTACGATTTACGATGCGAAGGGCAAGCAGATTCCGCTCACTGAGCGCGATGAAGAAATGACGAATAAGA
TTGGCTCTAAATTTTAA

Upstream 100 bases:

>100_bases
AGTGGAGGGGACGGCGTCTCCCCTGTGTGGGGAGTATTACGGTAGAGCGTGTGGTATAGGGAGCACCGTGTCGGTTCGGT
GCAGCTTGAGGGGGGAGTGC

Downstream 100 bases:

>100_bases
GGGGTGCAGGGAATGAAGGATATCCGGGATTTTGACAGTTTACAGATAAAGCTTGCCTCCCCTGATACCATTCGGGCATG
GTCCTATGGAGAGGTGAAAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1178; Mature: 1177

Protein sequence:

>1178_residues
MSARVCKTHRVYVGRDVRNFMDIPDLIEIQLRSYDTFLHGARNTPSGADTLISGTREELGLEDVFKTTFPIESSTGDMTL
EYQSYSLDEKNIKFSEAECKQKGLTYAIPLKALVDLRFNNTGEIRRKDIYMGDIPKMTERGTFIINGAERVVVSQIHRSP
GVVFSHEKDKEGREVFSSRIIPYRGSWLEFEIDQKKDLIYAKLDKKRRILGTVFLRALHYETREQIIEAFYAIEKTPVCQ
DRAEYELLTGKILARSVTVENEQGETRVLYKAGEKIHPHVIDDLLQNGICEVYIINLEAEGSLRSAVVINCLEREEMKFS
KSGAQDELSREEALCIVYSALRPSDPMTMDAAEKDLQTMFFSPRRYDLGRVGRYKLNKKFRSDSPTTECTLTLDDIVNTM
KFLIRMYSGDAQEDDIDHLGNRRIRSVGELMTNTLKTAFLRMERIAKERMSSKETETIKPQDLISIKPIMAAIKEFFGAS
QLSQFMDQVNPLAELTHKRRLNALGPGGLSRERAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSMANYARVNGYGFLEV
PYVRVRDGVVTKEIEYLDAMDEDRYYIGQDSTAVGPDGVIRVDHVSCRHRGDYSTRSPKDIQYMDVSPKQIISVSASLIP
FLEHDDANRALMGSNMQRQGVPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVSSEKIVVCSAAASGEEQEVVYP
LLKYQRTNQDTCYHQRPIVHVGDRVQVGDALADGPATYRGELALGRNILVGFVPWNGYNYEDAILISHRVVKEDMFTSVH
IKEFSTEVRETKLGSERMTNDIPNKSEKNLDNLDAEGIIRIGSKVRAGDVLIGKITPKSESETTPEFRLLNSIFGEKAKE
VRDSSLRVPHGVEGTVIDVQRLRRSEGDDLNPGVSEVVKVLIATKRKLREGDKMAGRHGNKGIVARILPEEDMPYLDDGT
PLDVCLNPLGVPSRMNIGQILESELGLAGLRLDEWYESPVFQSPSNEQIGEKLMQAGFPTNSKVMLRDGRTGDYFQNPVF
VGVIYFMKLAHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAANTLQELLTIKSDDMHGRSKIYE
AIVKGEASSPTGIPESFNVLVQELRGLALDFTIYDAKGKQIPLTERDEEMTNKIGSKF

Sequences:

>Translated_1178_residues
MSARVCKTHRVYVGRDVRNFMDIPDLIEIQLRSYDTFLHGARNTPSGADTLISGTREELGLEDVFKTTFPIESSTGDMTL
EYQSYSLDEKNIKFSEAECKQKGLTYAIPLKALVDLRFNNTGEIRRKDIYMGDIPKMTERGTFIINGAERVVVSQIHRSP
GVVFSHEKDKEGREVFSSRIIPYRGSWLEFEIDQKKDLIYAKLDKKRRILGTVFLRALHYETREQIIEAFYAIEKTPVCQ
DRAEYELLTGKILARSVTVENEQGETRVLYKAGEKIHPHVIDDLLQNGICEVYIINLEAEGSLRSAVVINCLEREEMKFS
KSGAQDELSREEALCIVYSALRPSDPMTMDAAEKDLQTMFFSPRRYDLGRVGRYKLNKKFRSDSPTTECTLTLDDIVNTM
KFLIRMYSGDAQEDDIDHLGNRRIRSVGELMTNTLKTAFLRMERIAKERMSSKETETIKPQDLISIKPIMAAIKEFFGAS
QLSQFMDQVNPLAELTHKRRLNALGPGGLSRERAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSMANYARVNGYGFLEV
PYVRVRDGVVTKEIEYLDAMDEDRYYIGQDSTAVGPDGVIRVDHVSCRHRGDYSTRSPKDIQYMDVSPKQIISVSASLIP
FLEHDDANRALMGSNMQRQGVPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVSSEKIVVCSAAASGEEQEVVYP
LLKYQRTNQDTCYHQRPIVHVGDRVQVGDALADGPATYRGELALGRNILVGFVPWNGYNYEDAILISHRVVKEDMFTSVH
IKEFSTEVRETKLGSERMTNDIPNKSEKNLDNLDAEGIIRIGSKVRAGDVLIGKITPKSESETTPEFRLLNSIFGEKAKE
VRDSSLRVPHGVEGTVIDVQRLRRSEGDDLNPGVSEVVKVLIATKRKLREGDKMAGRHGNKGIVARILPEEDMPYLDDGT
PLDVCLNPLGVPSRMNIGQILESELGLAGLRLDEWYESPVFQSPSNEQIGEKLMQAGFPTNSKVMLRDGRTGDYFQNPVF
VGVIYFMKLAHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAANTLQELLTIKSDDMHGRSKIYE
AIVKGEASSPTGIPESFNVLVQELRGLALDFTIYDAKGKQIPLTERDEEMTNKIGSKF
>Mature_1177_residues
SARVCKTHRVYVGRDVRNFMDIPDLIEIQLRSYDTFLHGARNTPSGADTLISGTREELGLEDVFKTTFPIESSTGDMTLE
YQSYSLDEKNIKFSEAECKQKGLTYAIPLKALVDLRFNNTGEIRRKDIYMGDIPKMTERGTFIINGAERVVVSQIHRSPG
VVFSHEKDKEGREVFSSRIIPYRGSWLEFEIDQKKDLIYAKLDKKRRILGTVFLRALHYETREQIIEAFYAIEKTPVCQD
RAEYELLTGKILARSVTVENEQGETRVLYKAGEKIHPHVIDDLLQNGICEVYIINLEAEGSLRSAVVINCLEREEMKFSK
SGAQDELSREEALCIVYSALRPSDPMTMDAAEKDLQTMFFSPRRYDLGRVGRYKLNKKFRSDSPTTECTLTLDDIVNTMK
FLIRMYSGDAQEDDIDHLGNRRIRSVGELMTNTLKTAFLRMERIAKERMSSKETETIKPQDLISIKPIMAAIKEFFGASQ
LSQFMDQVNPLAELTHKRRLNALGPGGLSRERAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSMANYARVNGYGFLEVP
YVRVRDGVVTKEIEYLDAMDEDRYYIGQDSTAVGPDGVIRVDHVSCRHRGDYSTRSPKDIQYMDVSPKQIISVSASLIPF
LEHDDANRALMGSNMQRQGVPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVSSEKIVVCSAAASGEEQEVVYPL
LKYQRTNQDTCYHQRPIVHVGDRVQVGDALADGPATYRGELALGRNILVGFVPWNGYNYEDAILISHRVVKEDMFTSVHI
KEFSTEVRETKLGSERMTNDIPNKSEKNLDNLDAEGIIRIGSKVRAGDVLIGKITPKSESETTPEFRLLNSIFGEKAKEV
RDSSLRVPHGVEGTVIDVQRLRRSEGDDLNPGVSEVVKVLIATKRKLREGDKMAGRHGNKGIVARILPEEDMPYLDDGTP
LDVCLNPLGVPSRMNIGQILESELGLAGLRLDEWYESPVFQSPSNEQIGEKLMQAGFPTNSKVMLRDGRTGDYFQNPVFV
GVIYFMKLAHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAANTLQELLTIKSDDMHGRSKIYEA
IVKGEASSPTGIPESFNVLVQELRGLALDFTIYDAKGKQIPLTERDEEMTNKIGSKF

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI33469941, Length=430, Percent_Identity=31.1627906976744, Blast_Score=166, Evalue=2e-40,
Organism=Homo sapiens, GI212286172, Length=430, Percent_Identity=31.1627906976744, Blast_Score=165, Evalue=3e-40,
Organism=Homo sapiens, GI238908505, Length=406, Percent_Identity=29.3103448275862, Blast_Score=164, Evalue=6e-40,
Organism=Homo sapiens, GI238908503, Length=406, Percent_Identity=29.3103448275862, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI4505941, Length=356, Percent_Identity=30.3370786516854, Blast_Score=159, Evalue=2e-38,
Organism=Escherichia coli, GI1790419, Length=940, Percent_Identity=46.8085106382979, Blast_Score=819, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=611, Percent_Identity=25.0409165302782, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17552304, Length=550, Percent_Identity=25.4545454545455, Blast_Score=163, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17506623, Length=184, Percent_Identity=38.5869565217391, Blast_Score=127, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324781, Length=406, Percent_Identity=30.5418719211823, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324725, Length=358, Percent_Identity=33.2402234636872, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6325267, Length=360, Percent_Identity=28.8888888888889, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17647877, Length=358, Percent_Identity=31.0055865921788, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17136444, Length=357, Percent_Identity=31.0924369747899, Blast_Score=159, Evalue=8e-39,
Organism=Drosophila melanogaster, GI17136446, Length=358, Percent_Identity=29.3296089385475, Blast_Score=132, Evalue=2e-30,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_TREPA (O83269)

Other databases:

- EMBL:   AE000520
- PIR:   C71350
- RefSeq:   NP_218681.1
- ProteinModelPortal:   O83269
- SMR:   O83269
- GeneID:   2611158
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0241
- NMPDR:   fig|243276.1.peg.240
- TIGR:   TP_0241
- HOGENOM:   HBG285547
- OMA:   QRDLTYA
- ProtClustDB:   PRK00405
- BioCyc:   TPAL243276:TP_0241-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 132449; Mature: 132317

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARVCKTHRVYVGRDVRNFMDIPDLIEIQLRSYDTFLHGARNTPSGADTLISGTREELG
CCCCEEECEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHCC
LEDVFKTTFPIESSTGDMTLEYQSYSLDEKNIKFSEAECKQKGLTYAIPLKALVDLRFNN
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCEEEECHHHEEEEEECC
TGEIRRKDIYMGDIPKMTERGTFIINGAERVVVSQIHRSPGVVFSHEKDKEGREVFSSRI
CCCEEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCC
IPYRGSWLEFEIDQKKDLIYAKLDKKRRILGTVFLRALHYETREQIIEAFYAIEKTPVCQ
CCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DRAEYELLTGKILARSVTVENEQGETRVLYKAGEKIHPHVIDDLLQNGICEVYIINLEAE
CCCHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEECC
GSLRSAVVINCLEREEMKFSKSGAQDELSREEALCIVYSALRPSDPMTMDAAEKDLQTMF
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHH
FSPRRYDLGRVGRYKLNKKFRSDSPTTECTLTLDDIVNTMKFLIRMYSGDAQEDDIDHLG
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHC
NRRIRSVGELMTNTLKTAFLRMERIAKERMSSKETETIKPQDLISIKPIMAAIKEFFGAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHH
QLSQFMDQVNPLAELTHKRRLNALGPGGLSRERAGFEVRDVHYTHYGRMCPIETPEGPNI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCE
GLIVSMANYARVNGYGFLEVPYVRVRDGVVTKEIEYLDAMDEDRYYIGQDSTAVGPDGVI
EEEEEECCCEEECCEEEEECCEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCEE
RVDHVSCRHRGDYSTRSPKDIQYMDVSPKQIISVSASLIPFLEHDDANRALMGSNMQRQG
EEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCC
VPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVSSEKIVVCSAAASGEEQEVVYP
CCEECCCCCCCCCCCHHHHCCCCCEEEEEECCCEEEEEECCEEEEEECCCCCCCCHHHHH
LLKYQRTNQDTCYHQRPIVHVGDRVQVGDALADGPATYRGELALGRNILVGFVPWNGYNY
HHHHHCCCCCCCHHCCCCEEECCEEEECCHHCCCCCCCCCCEEECCEEEEEEEECCCCCC
EDAILISHRVVKEDMFTSVHIKEFSTEVRETKLGSERMTNDIPNKSEKNLDNLDAEGIIR
CCEEEEHHHHHHHHHHHEEHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCEEE
IGSKVRAGDVLIGKITPKSESETTPEFRLLNSIFGEKAKEVRDSSLRVPHGVEGTVIDVQ
ECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHH
RLRRSEGDDLNPGVSEVVKVLIATKRKLREGDKMAGRHGNKGIVARILPEEDMPYLDDGT
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCCCCCCCCCCC
PLDVCLNPLGVPSRMNIGQILESELGLAGLRLDEWYESPVFQSPSNEQIGEKLMQAGFPT
CHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
NSKVMLRDGRTGDYFQNPVFVGVIYFMKLAHLVDDKMHARSTGPYSLVTQQPLGGKAQFG
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
GQRLGEMEVWALEAYGAANTLQELLTIKSDDMHGRSKIYEAIVKGEASSPTGIPESFNVL
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
VQELRGLALDFTIYDAKGKQIPLTERDEEMTNKIGSKF
HHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SARVCKTHRVYVGRDVRNFMDIPDLIEIQLRSYDTFLHGARNTPSGADTLISGTREELG
CCCEEECEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHCC
LEDVFKTTFPIESSTGDMTLEYQSYSLDEKNIKFSEAECKQKGLTYAIPLKALVDLRFNN
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCEEEECHHHEEEEEECC
TGEIRRKDIYMGDIPKMTERGTFIINGAERVVVSQIHRSPGVVFSHEKDKEGREVFSSRI
CCCEEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCC
IPYRGSWLEFEIDQKKDLIYAKLDKKRRILGTVFLRALHYETREQIIEAFYAIEKTPVCQ
CCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DRAEYELLTGKILARSVTVENEQGETRVLYKAGEKIHPHVIDDLLQNGICEVYIINLEAE
CCCHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEECC
GSLRSAVVINCLEREEMKFSKSGAQDELSREEALCIVYSALRPSDPMTMDAAEKDLQTMF
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHH
FSPRRYDLGRVGRYKLNKKFRSDSPTTECTLTLDDIVNTMKFLIRMYSGDAQEDDIDHLG
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHC
NRRIRSVGELMTNTLKTAFLRMERIAKERMSSKETETIKPQDLISIKPIMAAIKEFFGAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHH
QLSQFMDQVNPLAELTHKRRLNALGPGGLSRERAGFEVRDVHYTHYGRMCPIETPEGPNI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCE
GLIVSMANYARVNGYGFLEVPYVRVRDGVVTKEIEYLDAMDEDRYYIGQDSTAVGPDGVI
EEEEEECCCEEECCEEEEECCEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCEE
RVDHVSCRHRGDYSTRSPKDIQYMDVSPKQIISVSASLIPFLEHDDANRALMGSNMQRQG
EEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCC
VPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVSSEKIVVCSAAASGEEQEVVYP
CCEECCCCCCCCCCCHHHHCCCCCEEEEEECCCEEEEEECCEEEEEECCCCCCCCHHHHH
LLKYQRTNQDTCYHQRPIVHVGDRVQVGDALADGPATYRGELALGRNILVGFVPWNGYNY
HHHHHCCCCCCCHHCCCCEEECCEEEECCHHCCCCCCCCCCEEECCEEEEEEEECCCCCC
EDAILISHRVVKEDMFTSVHIKEFSTEVRETKLGSERMTNDIPNKSEKNLDNLDAEGIIR
CCEEEEHHHHHHHHHHHEEHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCEEE
IGSKVRAGDVLIGKITPKSESETTPEFRLLNSIFGEKAKEVRDSSLRVPHGVEGTVIDVQ
ECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHH
RLRRSEGDDLNPGVSEVVKVLIATKRKLREGDKMAGRHGNKGIVARILPEEDMPYLDDGT
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCCCCCCCCCCC
PLDVCLNPLGVPSRMNIGQILESELGLAGLRLDEWYESPVFQSPSNEQIGEKLMQAGFPT
CHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
NSKVMLRDGRTGDYFQNPVFVGVIYFMKLAHLVDDKMHARSTGPYSLVTQQPLGGKAQFG
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
GQRLGEMEVWALEAYGAANTLQELLTIKSDDMHGRSKIYEAIVKGEASSPTGIPESFNVL
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
VQELRGLALDFTIYDAKGKQIPLTERDEEMTNKIGSKF
HHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876