Click here to switch to the map view.

The map label for this gene is znuB [C]

Identifier: 189025270

GI number: 189025270

Start: 43650

End: 44450

Strand: Direct

Name: znuB [C]

Synonym: TPASS_0036

Alternate gene names: 189025270

Gene position: 43650-44450 (Clockwise)

Preceding gene: 189025269

Following gene: 189025273

Centisome position: 3.83

GC content: 52.18

Gene sequence:

>801_bases
ATGTTGCAGTACGCATTTATGCGCAACGCTTTTGTTGCTTCTTTTCTCATAGCCTTGTTGTGTCCTCTTGTGGGGATGCA
CTTAGTGCTCCGCCGTTACGCGCTCATGGGAGATGCACTTGCGCACGGTTCACTTGCAGGAGTATCTATTGCCGTTTCGT
GCGGCATCCATCCAGGATGGGGATCCTTTTTTTTCACTGCCTTGGTGGGGGTTTTGATAGAGTTTTTGCGCGCCTTTTTC
AAAAACCATCATGACCTGATTCTTTCAATAGTACTCTCCCTGAGTGTGGGTATTGCTGTCACGCTGTTGAGCTCTGGGCT
TATCCAGGCGGATATAGACAGCTATCTGTTTGGCAGCATACTGGTTGTTTCTACACGCGATTTGTGGATCATGCTCGCAC
TCAGCGTGTTCTGCGTAGGTACGCTAGCGTTGCGCTACCATCAGCTGCTGTACTTGGCATTTGATGAAGAGACCGCGCGT
ATCTGTGGCGTCGCAGCAGACGGGATAAACTACGTCGCGTCGGTGGTAATTTCAGCGACTATAGCAGCTTCTATAAAGAT
TACCGGTATTTTGGTGCTGAGCTCGCTCATGACCGTACCGGTTGCGACAGCGCTACAGCTGCGGGTGGGTTTCCTGCTTA
CGTTGGTGGCGGCGTTTCTATTTAGTATGCTGGACACGGCGCTGGGTTTGGTCTTCTCGTATTACTTGAACGTGGCCCCA
GGGGGATTCACCGCACTGGTCTCGGTGGTGGTACTGATGTTGGTTATCGCGCTCACACAGGTGGGCCGCGCCCGCACGTA
A

Upstream 100 bases:

>100_bases
AAGGACATGGCCATTTGTGTAATCCTCAGCAGTACGTCAGTGAGTTTTTGGATATGCAGAAAAAAGATGCGCTTGCCTGT
GCGCAGTGTCGGAGTCGGTG

Downstream 100 bases:

>100_bases
CCGGCTGGACGGGGTCCCGCGGAGCCCACAACCCACCCTGAGCTGGCGACTCCAGACTGACCGATTAGCCAGTCAGACTC
ACACGGGACCAGGGACACCT

Product: ABC transporter, permease protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGWGSFFFTALVGVLIEFLRAFF
KNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSILVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETAR
ICGVAADGINYVASVVISATIAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAP
GGFTALVSVVVLMLVIALTQVGRART

Sequences:

>Translated_266_residues
MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGWGSFFFTALVGVLIEFLRAFF
KNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSILVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETAR
ICGVAADGINYVASVVISATIAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAP
GGFTALVSVVVLMLVIALTQVGRART
>Mature_266_residues
MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGWGSFFFTALVGVLIEFLRAFF
KNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSILVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETAR
ICGVAADGINYVASVVISATIAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAP
GGFTALVSVVVLMLVIALTQVGRART

Specific function: Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y036_TREPA (O83079)

Other databases:

- EMBL:   AE000520
- PIR:   F71375
- RefSeq:   NP_218476.1
- ProteinModelPortal:   O83079
- IntAct:   O83079
- GeneID:   2611291
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0036
- NMPDR:   fig|243276.1.peg.35
- TIGR:   TP_0036
- HOGENOM:   HBG733179
- OMA:   YINSAPG
- ProtClustDB:   CLSK2300115
- BioCyc:   TPAL243276:TP_0036-MONOMER
- InterPro:   IPR001626

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 28383; Mature: 28383

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20227f9c)-; HASH(0x1fe73a0c)-; HASH(0x1fe1f340)-; HASH(0x1f00d87c)-; HASH(0x1fe7b7fc)-; HASH(0x1fe3c700)-; HASH(0x1f6635b0)-; HASH(0x1fe32740)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCH
GSFFFTALVGVLIEFLRAFFKNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSI
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETARICGVAADGINYVASVVISAT
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGFTALVSVVVLMLVIALTQVGRART
CHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCH
GSFFFTALVGVLIEFLRAFFKNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSI
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETARICGVAADGINYVASVVISAT
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGFTALVSVVVLMLVIALTQVGRART
CHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876