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The map label for this gene is murA1 [H]

Identifier: 188587430

GI number: 188587430

Start: 3073627

End: 3074910

Strand: Reverse

Name: murA1 [H]

Synonym: Nther_2840

Alternate gene names: 188587430

Gene position: 3074910-3073627 (Counterclockwise)

Preceding gene: 188587431

Following gene: 188587429

Centisome position: 97.14

GC content: 39.72

Gene sequence:

>1284_bases
TTGGATAAAATAAATGTGGTAGGTGGTAATAAGCTGACAGGGAAAGTTAGGATTAATGGAGCAAAAAATGCTTCTCTTCC
AATAATGGCTGCATCTTTGCTGGCTACCGAGCCAGTCAAAATTAATGAAGTCCCTCCATTAAAAGATGTTGGTACTATGT
GTGAGGTATTATCACACTTGGGATGTGAGGTTCGTGATTCCCTACCGGGTGAAGTCACTGTTAATCCAACAAATGTTAAA
AACATAGAAGCTCCCTATCATCTAATGCGCAAGATGAGGGCTTCATTTTTAGTCATGGGTCCACTGTTAGCAAAACAAGG
TCGAGCTAGAATATCTTTGCCGGGTGGCTGTGCCATTGGCAGTCGCCCAATCGATTTACATCTGAAAGGTTTCTCATCTT
TAGGTGCCGATATAAATTTTGGTCACGGCTACGTAGAAGCAGAAGCCAAAGGACTTCAGGGGAATAGAATCTATTTGGAT
TTTCCCAGTGTAGGTGCTACAGAAAATATCATGATGGCGGCAACTATGGCTAAAGGTACCACTGTCATAGAAAGTGCTGC
TGAAGAGCCAGAGATTGTAGACTTGGCTAATTTTCTAAATCAGATGGGTGCAAAGATCATCGGTGCGGGAACTGATACCA
TTAAAATAGAGGGTGTTGATGAACTTAAAGGGACAGATCACACTGTAATTCCAGACCGTATTGAAGCAGGCACCTTTATG
GCTGCTGCTGCCATTACTGGAGGAGAAGTTCTGGTTGAAAATGTTATATCTGATCATATCAGACCAGTAATTCGAAAAAT
GGAAGAAATGGGAGTAGAAATCACTGAAGAAGCTTCTGGTTTATTTGTCAAAAGTTATGATGAGTTAGCTCCTATTAAAT
TAAAAACTATGCCTTTCCCAGGTTTTCCAACAGATATGCAGCCACAGATGATGGCACTAATGACTAAAATTATCGGCGAA
AGTTCAGTTACGGAAACTGTTTTTGAAAATAGATTCAAACATGTTGATGAATTGCTTAGGATGAATGCTGATATTTCTAT
AGATGGAAGAACTGCTCAAGTTAAAGGCGGTAAAATGCTTACAGGAGCTCCTGTTAAGGCTTCAGACTTAAGAGCTGGAG
CGAGTCTAATTTTGGCAGGATTAATATCAGATGGAAAAACAGAGATATCGGATATCCATCATATTGAAAGAGGTTATTAC
AATATGGTTGAAAGGTTGCAAGATTTAGGTGCTAATATCTGGAGGAACGAAGAATTTTTAAAAGAGGCAGTTAACAACAG
TTAG

Upstream 100 bases:

>100_bases
CACTCTAAGATAATGAAGTTGATTTTTAGTTTTTATTATTTGCGGAAAAGTGTAAACTTATAAAGTCATTGATAGTTTTC
AGAATGGGAGGAATCATATC

Downstream 100 bases:

>100_bases
ATTAACTTTTATTCAAATTCATTATAAGAACACCTGGACATTAAGTTGTCCAGGTGTTCTTTTTTTTTGCATATAGCCAT
ATCTATAAATAGAGTCGTAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MDKINVVGGNKLTGKVRINGAKNASLPIMAASLLATEPVKINEVPPLKDVGTMCEVLSHLGCEVRDSLPGEVTVNPTNVK
NIEAPYHLMRKMRASFLVMGPLLAKQGRARISLPGGCAIGSRPIDLHLKGFSSLGADINFGHGYVEAEAKGLQGNRIYLD
FPSVGATENIMMAATMAKGTTVIESAAEEPEIVDLANFLNQMGAKIIGAGTDTIKIEGVDELKGTDHTVIPDRIEAGTFM
AAAAITGGEVLVENVISDHIRPVIRKMEEMGVEITEEASGLFVKSYDELAPIKLKTMPFPGFPTDMQPQMMALMTKIIGE
SSVTETVFENRFKHVDELLRMNADISIDGRTAQVKGGKMLTGAPVKASDLRAGASLILAGLISDGKTEISDIHHIERGYY
NMVERLQDLGANIWRNEEFLKEAVNNS

Sequences:

>Translated_427_residues
MDKINVVGGNKLTGKVRINGAKNASLPIMAASLLATEPVKINEVPPLKDVGTMCEVLSHLGCEVRDSLPGEVTVNPTNVK
NIEAPYHLMRKMRASFLVMGPLLAKQGRARISLPGGCAIGSRPIDLHLKGFSSLGADINFGHGYVEAEAKGLQGNRIYLD
FPSVGATENIMMAATMAKGTTVIESAAEEPEIVDLANFLNQMGAKIIGAGTDTIKIEGVDELKGTDHTVIPDRIEAGTFM
AAAAITGGEVLVENVISDHIRPVIRKMEEMGVEITEEASGLFVKSYDELAPIKLKTMPFPGFPTDMQPQMMALMTKIIGE
SSVTETVFENRFKHVDELLRMNADISIDGRTAQVKGGKMLTGAPVKASDLRAGASLILAGLISDGKTEISDIHHIERGYY
NMVERLQDLGANIWRNEEFLKEAVNNS
>Mature_427_residues
MDKINVVGGNKLTGKVRINGAKNASLPIMAASLLATEPVKINEVPPLKDVGTMCEVLSHLGCEVRDSLPGEVTVNPTNVK
NIEAPYHLMRKMRASFLVMGPLLAKQGRARISLPGGCAIGSRPIDLHLKGFSSLGADINFGHGYVEAEAKGLQGNRIYLD
FPSVGATENIMMAATMAKGTTVIESAAEEPEIVDLANFLNQMGAKIIGAGTDTIKIEGVDELKGTDHTVIPDRIEAGTFM
AAAAITGGEVLVENVISDHIRPVIRKMEEMGVEITEEASGLFVKSYDELAPIKLKTMPFPGFPTDMQPQMMALMTKIIGE
SSVTETVFENRFKHVDELLRMNADISIDGRTAQVKGGKMLTGAPVKASDLRAGASLILAGLISDGKTEISDIHHIERGYY
NMVERLQDLGANIWRNEEFLKEAVNNS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=50, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45996; Mature: 45996

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKINVVGGNKLTGKVRINGAKNASLPIMAASLLATEPVKINEVPPLKDVGTMCEVLSHL
CCCEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHC
GCEVRDSLPGEVTVNPTNVKNIEAPYHLMRKMRASFLVMGPLLAKQGRARISLPGGCAIG
CCEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
SRPIDLHLKGFSSLGADINFGHGYVEAEAKGLQGNRIYLDFPSVGATENIMMAATMAKGT
CCCEEEEEECHHHCCCCEECCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEHHCCC
TVIESAAEEPEIVDLANFLNQMGAKIIGAGTDTIKIEGVDELKGTDHTVIPDRIEAGTFM
HHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCEEEEECHHHCCCCCCCCCCCCCCCCCEE
AAAAITGGEVLVENVISDHIRPVIRKMEEMGVEITEEASGLFVKSYDELAPIKLKTMPFP
EHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCCCCCEEEEECCCC
GFPTDMQPQMMALMTKIIGESSVTETVFENRFKHVDELLRMNADISIDGRTAQVKGGKML
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCEEE
TGAPVKASDLRAGASLILAGLISDGKTEISDIHHIERGYYNMVERLQDLGANIWRNEEFL
ECCCCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHH
KEAVNNS
HHHHCCC
>Mature Secondary Structure
MDKINVVGGNKLTGKVRINGAKNASLPIMAASLLATEPVKINEVPPLKDVGTMCEVLSHL
CCCEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHC
GCEVRDSLPGEVTVNPTNVKNIEAPYHLMRKMRASFLVMGPLLAKQGRARISLPGGCAIG
CCEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
SRPIDLHLKGFSSLGADINFGHGYVEAEAKGLQGNRIYLDFPSVGATENIMMAATMAKGT
CCCEEEEEECHHHCCCCEECCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEHHCCC
TVIESAAEEPEIVDLANFLNQMGAKIIGAGTDTIKIEGVDELKGTDHTVIPDRIEAGTFM
HHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCEEEEECHHHCCCCCCCCCCCCCCCCCEE
AAAAITGGEVLVENVISDHIRPVIRKMEEMGVEITEEASGLFVKSYDELAPIKLKTMPFP
EHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCCCCCEEEEECCCC
GFPTDMQPQMMALMTKIIGESSVTETVFENRFKHVDELLRMNADISIDGRTAQVKGGKML
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCEEE
TGAPVKASDLRAGASLILAGLISDGKTEISDIHHIERGYYNMVERLQDLGANIWRNEEFL
ECCCCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHH
KEAVNNS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]