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The map label for this gene is ctpB [H]

Identifier: 188587413

GI number: 188587413

Start: 3053202

End: 3054146

Strand: Reverse

Name: ctpB [H]

Synonym: Nther_2822

Alternate gene names: 188587413

Gene position: 3054146-3053202 (Counterclockwise)

Preceding gene: 188587414

Following gene: 188587411

Centisome position: 96.48

GC content: 35.77

Gene sequence:

>945_bases
TTGGCTGGTTTTAATAAAAAAACTTTTTTAAACTACTCTTTGTTTATTTTTGCAGTGCTTATCGCTTTAATGATTTTTAT
TCCAGAGGCGTATAGTGCTAGCCCTGGCCCTGAAAAATTAGAAGAAAATATTGACGCTAACCCTCTTATTCCCGACTTAA
CAAAAGAGGAGGAGTTGCGCGAAAAACTGGTTGAAGAAGCCGTTGAAATTTTAGAGACTTATTATGTGGAGGAACCTCCC
CATGATATTCAAGATGCAGAAAGTTTAGAAGAGCTTTTTGAAATATTAGATGACCCTTATACCATGTACTTGTCTGAAAA
AGAAAAAGAAGAATTTGCCGAATACTCTGGCGACCCTGTAAATGGTAAGGTTATTGCAGACTCTTTAGGTTATATTCAGA
TTAAAGAATTTAGCGAAAACTCTAGTGAAGATTTCAAACAAGTAATTATAGAACTTTTAGAAGAGGATATACAGGGTTGG
GTAGTAAACCTGCGTGGTAATCCTGGAGGAACAGTTGAAGATGCAGGTAAAATTTTAGGTCATTTTGTTGGTGAACAAGA
TATCGTGGTGGCAGAAAATTATAGGGAACAAATTATTTGCGGATCTAAAGCAACTGAACCTCAGCTAGAAAAACCAGCAG
TTTTTTTAGTTGATCGAAGGTCGGCTAGTGCAGCTGAAATGTTTGCTTATGCTATTAAAAATCAGAATAGAGGTTTAGTT
ATCGGGGAGAAAACTTTTGGCAAAGGTACTGTGCAAAATTTATTCCCCCTATCAGAAGGGGGAGGGTTGTTAACAACAAT
ATATGAAGTGAAAACATTAGATGGAAAAACAATTGAAGGCAAGGGGATTGAACCGCATTTTGATTTAACGGATATTGCCA
TTAAGACTGAAATTTTGAAGACGACTAAGAGATCTTTGATTAAAGATGTATTGTCAGATAATTAA

Upstream 100 bases:

>100_bases
CGAGATGAGAATTGGATTATCTTAAATCCTTTTTATATGTGGGGTCAATAAATTAAGACTAATAGTTATCTATTGAGCTT
GTTTTTAAGGAGGAATTGAT

Downstream 100 bases:

>100_bases
CTTATCCATTCTTGTAAATGTGGTGATATTTTTGCAAGGAAGTAGTTCTGGTTTCTTTTCTCACAAAAATTGAAGATTTT
TTTGGATACCTCTAATAGCT

Product: peptidase S41

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAGFNKKTFLNYSLFIFAVLIALMIFIPEAYSASPGPEKLEENIDANPLIPDLTKEEELREKLVEEAVEILETYYVEEPP
HDIQDAESLEELFEILDDPYTMYLSEKEKEEFAEYSGDPVNGKVIADSLGYIQIKEFSENSSEDFKQVIIELLEEDIQGW
VVNLRGNPGGTVEDAGKILGHFVGEQDIVVAENYREQIICGSKATEPQLEKPAVFLVDRRSASAAEMFAYAIKNQNRGLV
IGEKTFGKGTVQNLFPLSEGGGLLTTIYEVKTLDGKTIEGKGIEPHFDLTDIAIKTEILKTTKRSLIKDVLSDN

Sequences:

>Translated_314_residues
MAGFNKKTFLNYSLFIFAVLIALMIFIPEAYSASPGPEKLEENIDANPLIPDLTKEEELREKLVEEAVEILETYYVEEPP
HDIQDAESLEELFEILDDPYTMYLSEKEKEEFAEYSGDPVNGKVIADSLGYIQIKEFSENSSEDFKQVIIELLEEDIQGW
VVNLRGNPGGTVEDAGKILGHFVGEQDIVVAENYREQIICGSKATEPQLEKPAVFLVDRRSASAAEMFAYAIKNQNRGLV
IGEKTFGKGTVQNLFPLSEGGGLLTTIYEVKTLDGKTIEGKGIEPHFDLTDIAIKTEILKTTKRSLIKDVLSDN
>Mature_313_residues
AGFNKKTFLNYSLFIFAVLIALMIFIPEAYSASPGPEKLEENIDANPLIPDLTKEEELREKLVEEAVEILETYYVEEPPH
DIQDAESLEELFEILDDPYTMYLSEKEKEEFAEYSGDPVNGKVIADSLGYIQIKEFSENSSEDFKQVIIELLEEDIQGWV
VNLRGNPGGTVEDAGKILGHFVGEQDIVVAENYREQIICGSKATEPQLEKPAVFLVDRRSASAAEMFAYAIKNQNRGLVI
GEKTFGKGTVQNLFPLSEGGGLLTTIYEVKTLDGKTIEGKGIEPHFDLTDIAIKTEILKTTKRSLIKDVLSDN

Specific function: Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Forespore intermembrane space. Note=Is expressed in both the mother cell and forespore compartments but that synthesis in the forespore is both necessary and sufficient for the proper timing of pro-sigma-K processing [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=173, Percent_Identity=31.2138728323699, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 35083; Mature: 34952

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFNKKTFLNYSLFIFAVLIALMIFIPEAYSASPGPEKLEENIDANPLIPDLTKEEELR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHH
EKLVEEAVEILETYYVEEPPHDIQDAESLEELFEILDDPYTMYLSEKEKEEFAEYSGDPV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCC
NGKVIADSLGYIQIKEFSENSSEDFKQVIIELLEEDIQGWVVNLRGNPGGTVEDAGKILG
CCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHH
HFVGEQDIVVAENYREQIICGSKATEPQLEKPAVFLVDRRSASAAEMFAYAIKNQNRGLV
HHCCCCCEEEECCCCHHEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEE
IGEKTFGKGTVQNLFPLSEGGGLLTTIYEVKTLDGKTIEGKGIEPHFDLTDIAIKTEILK
EECCCCCCCCHHHCCCCCCCCCEEEEEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHH
TTKRSLIKDVLSDN
HHHHHHHHHHHCCC
>Mature Secondary Structure 
AGFNKKTFLNYSLFIFAVLIALMIFIPEAYSASPGPEKLEENIDANPLIPDLTKEEELR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHH
EKLVEEAVEILETYYVEEPPHDIQDAESLEELFEILDDPYTMYLSEKEKEEFAEYSGDPV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCC
NGKVIADSLGYIQIKEFSENSSEDFKQVIIELLEEDIQGWVVNLRGNPGGTVEDAGKILG
CCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHH
HFVGEQDIVVAENYREQIICGSKATEPQLEKPAVFLVDRRSASAAEMFAYAIKNQNRGLV
HHCCCCCEEEECCCCHHEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEE
IGEKTFGKGTVQNLFPLSEGGGLLTTIYEVKTLDGKTIEGKGIEPHFDLTDIAIKTEILK
EECCCCCCCCHHHCCCCCCCCCEEEEEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHH
TTKRSLIKDVLSDN
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9570401; 9384377 [H]