Click here to switch to the map view.

The map label for this gene is pyrK [H]

Identifier: 188587356

GI number: 188587356

Start: 2983531

End: 2984358

Strand: Reverse

Name: pyrK [H]

Synonym: Nther_2763

Alternate gene names: 188587356

Gene position: 2984358-2983531 (Counterclockwise)

Preceding gene: 188587357

Following gene: 188587355

Centisome position: 94.28

GC content: 41.55

Gene sequence:

>828_bases
ATGTGGTATGATGAATTAGGAAAAATAAGCTATCACACTAAGATTGCCCCACAAATTTTTTTAATGAAGATAAAGCTTCC
AAAAATTAGCACTAGTATTCATCCGGGGCAGTTTGTCAACATCCAAGTCAATGGAGCTTATGATCAGAAGGAAGACAGCT
TTGCGACAATTATAAGTGATCCCCTGCTCAGAAGGCCCATAAGCGTTTACGATGTGTGTCCCCAAGAGGGGGAACTATCT
ATCATGTATCAGGTTGTCGGCCGTGGAACGCAAATTTTGTCATCTCAGGCCGAAGGAACAAGACTAAAAGTTATGGGTCC
TTTAGGAAACGGCTTTTCGTTAGATGAAGGGCAGAAAGTTGCATTAGTTTCAGGAGGGATTGGCATTGCACCCTTATACC
TGCTGAGTAAAAAACTTGCTTCTAATAATTGTCAGCCCCACCTTCTAGCAGGTTTTTCAGGGGAAGAGCAAGTCAGGTTA
CTGCAAGATTTTCATGAATTGAATAATATGAACATCAAACTGGCAACTGATGACGGGTCTGCGGGCTACCATGGGCAGGT
AACTGATCTATTGAAAAATTTTTTGTCAAGCTATCAGGAACAAATAGATATGGTGGTTACTTGTGGGCCAGAAATAATGA
TGAAAAAAGTTGTAGATTTAGCTACTCGAGCTAATCTACCTGTAAAATTATCTGTAGAACGAAAAATGGCCTGTGGAGTT
GGTGCCTGTCTTGGTTGCACCTGTGAATCTGTGGATAATCAATCCTACAAGCATGCATGCATCGATGGTCCTGTCTTCTG
GGGAAATGAGGTGAAACTAAATGGCTGA

Upstream 100 bases:

>100_bases
GGCAAAAACAGCCCCTTTGCTGGATGGGAGTTGGAAGGTAAAATCGTCGCTACAATGGTTTCAGGGGAATTTAGTTATCG
ACAATTTGGGAGCGATGACC

Downstream 100 bases:

>100_bases
TCTTAAGGTGAATTTTGCAGGAATACCAATGAAAAATCCTGTAGCATCGGCATCGGGAACTTTTGGATTTGGTTTTGAAT
ATCAATCGGTCATAAGTCCA

Product: oxidoreductase FAD/NAD(P)-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MWYDELGKISYHTKIAPQIFLMKIKLPKISTSIHPGQFVNIQVNGAYDQKEDSFATIISDPLLRRPISVYDVCPQEGELS
IMYQVVGRGTQILSSQAEGTRLKVMGPLGNGFSLDEGQKVALVSGGIGIAPLYLLSKKLASNNCQPHLLAGFSGEEQVRL
LQDFHELNNMNIKLATDDGSAGYHGQVTDLLKNFLSSYQEQIDMVVTCGPEIMMKKVVDLATRANLPVKLSVERKMACGV
GACLGCTCESVDNQSYKHACIDGPVFWGNEVKLNG

Sequences:

>Translated_275_residues
MWYDELGKISYHTKIAPQIFLMKIKLPKISTSIHPGQFVNIQVNGAYDQKEDSFATIISDPLLRRPISVYDVCPQEGELS
IMYQVVGRGTQILSSQAEGTRLKVMGPLGNGFSLDEGQKVALVSGGIGIAPLYLLSKKLASNNCQPHLLAGFSGEEQVRL
LQDFHELNNMNIKLATDDGSAGYHGQVTDLLKNFLSSYQEQIDMVVTCGPEIMMKKVVDLATRANLPVKLSVERKMACGV
GACLGCTCESVDNQSYKHACIDGPVFWGNEVKLNG
>Mature_275_residues
MWYDELGKISYHTKIAPQIFLMKIKLPKISTSIHPGQFVNIQVNGAYDQKEDSFATIISDPLLRRPISVYDVCPQEGELS
IMYQVVGRGTQILSSQAEGTRLKVMGPLGNGFSLDEGQKVALVSGGIGIAPLYLLSKKLASNNCQPHLLAGFSGEEQVRL
LQDFHELNNMNIKLATDDGSAGYHGQVTDLLKNFLSSYQEQIDMVVTCGPEIMMKKVVDLATRANLPVKLSVERKMACGV
GACLGCTCESVDNQSYKHACIDGPVFWGNEVKLNG

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 30086; Mature: 30086

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWYDELGKISYHTKIAPQIFLMKIKLPKISTSIHPGQFVNIQVNGAYDQKEDSFATIISD
CCHHHHCCEEEEEECCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCC
PLLRRPISVYDVCPQEGELSIMYQVVGRGTQILSSQAEGTRLKVMGPLGNGFSLDEGQKV
HHHHCCCCCEECCCCCCCEEEEEEECCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEE
ALVSGGIGIAPLYLLSKKLASNNCQPHLLAGFSGEEQVRLLQDFHELNNMNIKLATDDGS
EEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCC
AGYHGQVTDLLKNFLSSYQEQIDMVVTCGPEIMMKKVVDLATRANLPVKLSVERKMACGV
CCCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECHHHHCCC
GACLGCTCESVDNQSYKHACIDGPVFWGNEVKLNG
CHHHCCCCCCCCCCCCCEEECCCCEEECCEEEECC
>Mature Secondary Structure
MWYDELGKISYHTKIAPQIFLMKIKLPKISTSIHPGQFVNIQVNGAYDQKEDSFATIISD
CCHHHHCCEEEEEECCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCC
PLLRRPISVYDVCPQEGELSIMYQVVGRGTQILSSQAEGTRLKVMGPLGNGFSLDEGQKV
HHHHCCCCCEECCCCCCCEEEEEEECCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEE
ALVSGGIGIAPLYLLSKKLASNNCQPHLLAGFSGEEQVRLLQDFHELNNMNIKLATDDGS
EEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCC
AGYHGQVTDLLKNFLSSYQEQIDMVVTCGPEIMMKKVVDLATRANLPVKLSVERKMACGV
CCCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECHHHHCCC
GACLGCTCESVDNQSYKHACIDGPVFWGNEVKLNG
CHHHCCCCCCCCCCCCCEEECCCCEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]