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The map label for this gene is csd [H]

Identifier: 188587293

GI number: 188587293

Start: 2908464

End: 2909606

Strand: Reverse

Name: csd [H]

Synonym: Nther_2696

Alternate gene names: 188587293

Gene position: 2909606-2908464 (Counterclockwise)

Preceding gene: 188587294

Following gene: 188587292

Centisome position: 91.91

GC content: 40.68

Gene sequence:

>1143_bases
ATGGTCTATCTAGATAACGGTGCCACCAGCTGGCCCAAACCGGAACAAGTTTATCGAGCAGTAGATGAGTGCCTACGCTC
AGGCGGGAACCCAGGCAGGGGTGTCAACCAGAGTTCTCTGGAAATGAGTCGAATTATTTTTGAGGCTAGGTACGAACTGG
CGAATTTTTTAAATATCCCAAATGAAGATAGATTGATTTTTACCAAAAATGTAACAGAAGCTATAAATATGGTGTTAAAG
GGAATATTGGAGACAGGTGATCATGTTTTGATAAGTCCTATGGAACACAACTCTGTAGTAAGACCCCTAGAATATTTAAA
GGAGAATAGAGGGATTAGTTACGATCTGATTCCGTCCGACTCTCAAGGAAGGTTAAATATAAGCGAGATTGAATCCTTGA
TAACGGAAAATACTAAATTATTAGTTTTTACCCATGCTTCTAATGTTTTGGGGACAGTCTTGCCTGCTCGTCAATTAGTG
CAAATCGCAAAAAGCCATGGCTTATACACATTAATAGATGGAGCGCAAAGTGCAGGGAATATGGAAGTGGATGTAAAAGC
TTTGAAGGCAGATTTTTTTGCTTTTACCGGTCACAAAGGCCTTTTAGGGCCGCAAGGTACTGGAGGACTATTTGTCAGGG
AAGGAATTGAACTGGAACCCTTGATTCATGGAGGAACAGGAAGCAATTCCAGATCATTGAAACAGGATGGGATGTTTCCC
GATGATTTTGAAAGCGGAACTGTTAATATGCCTGGAATTGCCGGCTTGAAAGAGGGTGTCAAATATAGTCGTGATAACCT
GACAGATATTATTTCATCAAAACAACATTTGATGGAAAAACTTATGGATTATCTTCTAGATAAATCTGAAATTGATGTTT
ACGGACCTCCCTCTTCTTCTATTTCGGAACGAGTTGGACTGGTAACCTTTAATTTGAAAAACATTGCTGCAGATAAAGTG
GGACAAATTTTGGACAGCGAGTATGAAATAATAACCCGAACGGGACTTCACTGTTCTCCCCTGGCCCATCGAACTGCTGG
CAGTATAGACTTTGGAGGAGTAAGAGTGAGTATTGGCCCCTTCACCCGAGAAGATGAAATAGACCAGCTCATACAAGCTT
TGGATCAAATTATTAATCAATAG

Upstream 100 bases:

>100_bases
CAATAAAAACTATTTGTTACATTAATTCCAATCCCTGTATAATTTAAGTGAGCATTTGTATCGGGATGTAATTATCTTTA
CAAAACTAGGGGTGAATTTA

Downstream 100 bases:

>100_bases
CAATAACAGATTGACAAAAGATTACCTGAATTGACAATCAAGAATCAACAAAGTTCTGATTACGCAGTTGATACAATAAA
AGCACCCAGAAATTATAGGG

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MVYLDNGATSWPKPEQVYRAVDECLRSGGNPGRGVNQSSLEMSRIIFEARYELANFLNIPNEDRLIFTKNVTEAINMVLK
GILETGDHVLISPMEHNSVVRPLEYLKENRGISYDLIPSDSQGRLNISEIESLITENTKLLVFTHASNVLGTVLPARQLV
QIAKSHGLYTLIDGAQSAGNMEVDVKALKADFFAFTGHKGLLGPQGTGGLFVREGIELEPLIHGGTGSNSRSLKQDGMFP
DDFESGTVNMPGIAGLKEGVKYSRDNLTDIISSKQHLMEKLMDYLLDKSEIDVYGPPSSSISERVGLVTFNLKNIAADKV
GQILDSEYEIITRTGLHCSPLAHRTAGSIDFGGVRVSIGPFTREDEIDQLIQALDQIINQ

Sequences:

>Translated_380_residues
MVYLDNGATSWPKPEQVYRAVDECLRSGGNPGRGVNQSSLEMSRIIFEARYELANFLNIPNEDRLIFTKNVTEAINMVLK
GILETGDHVLISPMEHNSVVRPLEYLKENRGISYDLIPSDSQGRLNISEIESLITENTKLLVFTHASNVLGTVLPARQLV
QIAKSHGLYTLIDGAQSAGNMEVDVKALKADFFAFTGHKGLLGPQGTGGLFVREGIELEPLIHGGTGSNSRSLKQDGMFP
DDFESGTVNMPGIAGLKEGVKYSRDNLTDIISSKQHLMEKLMDYLLDKSEIDVYGPPSSSISERVGLVTFNLKNIAADKV
GQILDSEYEIITRTGLHCSPLAHRTAGSIDFGGVRVSIGPFTREDEIDQLIQALDQIINQ
>Mature_380_residues
MVYLDNGATSWPKPEQVYRAVDECLRSGGNPGRGVNQSSLEMSRIIFEARYELANFLNIPNEDRLIFTKNVTEAINMVLK
GILETGDHVLISPMEHNSVVRPLEYLKENRGISYDLIPSDSQGRLNISEIESLITENTKLLVFTHASNVLGTVLPARQLV
QIAKSHGLYTLIDGAQSAGNMEVDVKALKADFFAFTGHKGLLGPQGTGGLFVREGIELEPLIHGGTGSNSRSLKQDGMFP
DDFESGTVNMPGIAGLKEGVKYSRDNLTDIISSKQHLMEKLMDYLLDKSEIDVYGPPSSSISERVGLVTFNLKNIAADKV
GQILDSEYEIITRTGLHCSPLAHRTAGSIDFGGVRVSIGPFTREDEIDQLIQALDQIINQ

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=397, Percent_Identity=23.9294710327456, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI156713448, Length=436, Percent_Identity=25.6880733944954, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1787970, Length=390, Percent_Identity=34.3589743589744, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789175, Length=390, Percent_Identity=28.4615384615385, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI48994898, Length=401, Percent_Identity=24.6882793017456, Blast_Score=114, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=294, Percent_Identity=27.891156462585, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17533177, Length=336, Percent_Identity=24.702380952381, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=390, Percent_Identity=26.4102564102564, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI20129463, Length=293, Percent_Identity=27.9863481228669, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41676; Mature: 41676

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYLDNGATSWPKPEQVYRAVDECLRSGGNPGRGVNQSSLEMSRIIFEARYELANFLNIP
CEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NEDRLIFTKNVTEAINMVLKGILETGDHVLISPMEHNSVVRPLEYLKENRGISYDLIPSD
CCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCC
SQGRLNISEIESLITENTKLLVFTHASNVLGTVLPARQLVQIAKSHGLYTLIDGAQSAGN
CCCCEEHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
MEVDVKALKADFFAFTGHKGLLGPQGTGGLFVREGIELEPLIHGGTGSNSRSLKQDGMFP
CEEEHHHHHHHHHEEECCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCHHHCCCCC
DDFESGTVNMPGIAGLKEGVKYSRDNLTDIISSKQHLMEKLMDYLLDKSEIDVYGPPSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
ISERVGLVTFNLKNIAADKVGQILDSEYEIITRTGLHCSPLAHRTAGSIDFGGVRVSIGP
HHHCCCEEEEEHHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHCCCCCEECCEEEEECC
FTREDEIDQLIQALDQIINQ
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVYLDNGATSWPKPEQVYRAVDECLRSGGNPGRGVNQSSLEMSRIIFEARYELANFLNIP
CEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NEDRLIFTKNVTEAINMVLKGILETGDHVLISPMEHNSVVRPLEYLKENRGISYDLIPSD
CCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCC
SQGRLNISEIESLITENTKLLVFTHASNVLGTVLPARQLVQIAKSHGLYTLIDGAQSAGN
CCCCEEHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
MEVDVKALKADFFAFTGHKGLLGPQGTGGLFVREGIELEPLIHGGTGSNSRSLKQDGMFP
CEEEHHHHHHHHHEEECCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCHHHCCCCC
DDFESGTVNMPGIAGLKEGVKYSRDNLTDIISSKQHLMEKLMDYLLDKSEIDVYGPPSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
ISERVGLVTFNLKNIAADKVGQILDSEYEIITRTGLHCSPLAHRTAGSIDFGGVRVSIGP
HHHCCCEEEEEHHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHCCCCCEECCEEEEECC
FTREDEIDQLIQALDQIINQ
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]