Click here to switch to the map view.

The map label for this gene is yqiR [H]

Identifier: 188587199

GI number: 188587199

Start: 2793258

End: 2795015

Strand: Reverse

Name: yqiR [H]

Synonym: Nther_2600

Alternate gene names: 188587199

Gene position: 2795015-2793258 (Counterclockwise)

Preceding gene: 188587200

Following gene: 188587198

Centisome position: 88.29

GC content: 36.8

Gene sequence:

>1758_bases
TTGTTTGATAGCTTAATGAATGCTATAAATGATGCTCTAATAGTTACCGATGAGCACAACAAAATAGAGTGTTTTAATTA
TAAAGCAGAAGAAACTTTTAACATTAGTCACAATCACTTAGGGGAAAAAATTGAAGGGATTATTTTTATACCCGATGACT
TAAAGAAGAGTGATACTATAACCGAAGGTAAAAAGGAATCACAAAGAAGGATAAATTATTACGGGAAAACATTATCCGTT
ATAAAAACACCTATTATTGAACCTACTATTGAAAATCAATGCCATCTCGGTAATTACTATATATTTGAAGATATATCGGA
CTCCGTCAAACTTAAAAGAGAACTTTCTAATGCCAGATCATCTGCTAATGCCATGGAAAATGTGCTGGAAAAAGCCTATG
ATGGCATAGTTATGATAGATCACAATGGAATAATTACTAAGTTCAATAGTGCTTATCAACAGTTTACCGGGATTTCGGAA
CAAGAAGCACTGGGAAAACATGTGACAGAAGTTATTGAAAATACCAGAATGCATAAAGTTCTGGAGACGGGGAAGCCGGA
AATAGGAGAAATTCAAAAAATCAAAGGCTGCGAAATGGTGGCTACCAGAGTCCCCATTTATGAAGAAGGGGAGATAGTTG
GGGTTTTAGGAAAAGTGTTGTTTAGAGATATCAAAGAAGTAAAAGCCCTGGCTGAAAGGTTAGACGCTGCTACTAACGAA
CTCGATTATTATAAAGGTGAAGTCAGAAAGCTCAAGGGTAGTAAATATAATTTTGAGAATATAGTGGGTTCAAGTAAAAA
AATCATAGAAGCCAAAGAAATGGCTAAAATAGCTTCTCAAAGTGATTCCACCGTCCTTATCCGAGGTGAAAGCGGTACCG
GGAAGGAATTATTCGCCCATGCCATTCACGATGGGAGCTTAAGAAGATACGGGGCCTTTATCAGGGTTAACTGTGCAGCT
ATTCCAGAAAATCTATTGGAAGCGGAACTCTTTGGTTATGAAAAAGGTGCCTTTACGGGTGCTAACAAAGAAGGGAAACC
TGGAAAATTTGAACTTGCCAATGGAGGAACCATATTTTTAGACGAAATCGGCGATATGCCCTTTGATATGCAGGTGAAAC
TACTGCGAGCCCTACAAGAACGGGAAGTGCAAAGAATAGGAAGTGAGCGGGTAATTGATTTAGATGTCAGAATTATAGCC
TCTACGAACAGAAATTTAGAACAGTTGATTGCTCAGGACAAATTTCGAGAAGACCTTTATTATCGCTTGAATGTATTTAA
TATTAATGTTCCGCCATTGAGGGAGATGAAAGATGATTTAGAAAAGCTGATCAATTTTATAATCAAAGACTTGAATGACG
AAATGGGTCTAAATGTCAATGGCGTTTCTTCGGAAGCAAATAAAATATTAAATTCCTATCACTGGCCCGGCAATATCCGG
GAACTGAAAAATGTGTTGGAAAGGTCAATGAATGTGGCAAAAGGCAATATTATTACAAAAGACTGCATTCCCCAGTATTT
ATTAACATGGGCTGGGGCAGAAGAACAGCAAAATAACAGTAATAGTAAATCCCATGAAATAAATTTGCATAATTTAGAGC
TCAGATCAGTAGTCAAAGAAGCCGAAAAACTGGCCATTGAAACCGCCCTAAAACAGACTAATAATAACAAGAAAAAAGCA
GCCGAACTCTTAAATATTCACAGATCGGGCTTATACAAAAAACTCGAAGAATATAATATTTCAGACCAAACTACTTGA

Upstream 100 bases:

>100_bases
CAGAAACCGGAGAAGAATATACAATTAACAATATGTCCGAAGATCAAGCTTTAAAATACAAGAAACAAAACGGAGGTGTC
TAAAAATTAACAAGGAAACT

Downstream 100 bases:

>100_bases
AAAATTCGTCACGCAATCTCGTCTACGCATTCCATCACGCGCATTCTCATCACGCATTCTTATCGCGCATTCTTATCACG
CGTTCCATCACGCATTCCAT

Product: PAS modulated sigma54 specific transcriptional regulator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MFDSLMNAINDALIVTDEHNKIECFNYKAEETFNISHNHLGEKIEGIIFIPDDLKKSDTITEGKKESQRRINYYGKTLSV
IKTPIIEPTIENQCHLGNYYIFEDISDSVKLKRELSNARSSANAMENVLEKAYDGIVMIDHNGIITKFNSAYQQFTGISE
QEALGKHVTEVIENTRMHKVLETGKPEIGEIQKIKGCEMVATRVPIYEEGEIVGVLGKVLFRDIKEVKALAERLDAATNE
LDYYKGEVRKLKGSKYNFENIVGSSKKIIEAKEMAKIASQSDSTVLIRGESGTGKELFAHAIHDGSLRRYGAFIRVNCAA
IPENLLEAELFGYEKGAFTGANKEGKPGKFELANGGTIFLDEIGDMPFDMQVKLLRALQEREVQRIGSERVIDLDVRIIA
STNRNLEQLIAQDKFREDLYYRLNVFNINVPPLREMKDDLEKLINFIIKDLNDEMGLNVNGVSSEANKILNSYHWPGNIR
ELKNVLERSMNVAKGNIITKDCIPQYLLTWAGAEEQQNNSNSKSHEINLHNLELRSVVKEAEKLAIETALKQTNNNKKKA
AELLNIHRSGLYKKLEEYNISDQTT

Sequences:

>Translated_585_residues
MFDSLMNAINDALIVTDEHNKIECFNYKAEETFNISHNHLGEKIEGIIFIPDDLKKSDTITEGKKESQRRINYYGKTLSV
IKTPIIEPTIENQCHLGNYYIFEDISDSVKLKRELSNARSSANAMENVLEKAYDGIVMIDHNGIITKFNSAYQQFTGISE
QEALGKHVTEVIENTRMHKVLETGKPEIGEIQKIKGCEMVATRVPIYEEGEIVGVLGKVLFRDIKEVKALAERLDAATNE
LDYYKGEVRKLKGSKYNFENIVGSSKKIIEAKEMAKIASQSDSTVLIRGESGTGKELFAHAIHDGSLRRYGAFIRVNCAA
IPENLLEAELFGYEKGAFTGANKEGKPGKFELANGGTIFLDEIGDMPFDMQVKLLRALQEREVQRIGSERVIDLDVRIIA
STNRNLEQLIAQDKFREDLYYRLNVFNINVPPLREMKDDLEKLINFIIKDLNDEMGLNVNGVSSEANKILNSYHWPGNIR
ELKNVLERSMNVAKGNIITKDCIPQYLLTWAGAEEQQNNSNSKSHEINLHNLELRSVVKEAEKLAIETALKQTNNNKKKA
AELLNIHRSGLYKKLEEYNISDQTT
>Mature_585_residues
MFDSLMNAINDALIVTDEHNKIECFNYKAEETFNISHNHLGEKIEGIIFIPDDLKKSDTITEGKKESQRRINYYGKTLSV
IKTPIIEPTIENQCHLGNYYIFEDISDSVKLKRELSNARSSANAMENVLEKAYDGIVMIDHNGIITKFNSAYQQFTGISE
QEALGKHVTEVIENTRMHKVLETGKPEIGEIQKIKGCEMVATRVPIYEEGEIVGVLGKVLFRDIKEVKALAERLDAATNE
LDYYKGEVRKLKGSKYNFENIVGSSKKIIEAKEMAKIASQSDSTVLIRGESGTGKELFAHAIHDGSLRRYGAFIRVNCAA
IPENLLEAELFGYEKGAFTGANKEGKPGKFELANGGTIFLDEIGDMPFDMQVKLLRALQEREVQRIGSERVIDLDVRIIA
STNRNLEQLIAQDKFREDLYYRLNVFNINVPPLREMKDDLEKLINFIIKDLNDEMGLNVNGVSSEANKILNSYHWPGNIR
ELKNVLERSMNVAKGNIITKDCIPQYLLTWAGAEEQQNNSNSKSHEINLHNLELRSVVKEAEKLAIETALKQTNNNKKKA
AELLNIHRSGLYKKLEEYNISDQTT

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=418, Percent_Identity=39.9521531100478, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=44.3076923076923, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1789087, Length=359, Percent_Identity=38.9972144846797, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI87082117, Length=243, Percent_Identity=48.1481481481481, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1790299, Length=374, Percent_Identity=38.5026737967914, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1790437, Length=353, Percent_Identity=41.0764872521246, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788905, Length=251, Percent_Identity=48.207171314741, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1786524, Length=404, Percent_Identity=34.6534653465347, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI87082152, Length=345, Percent_Identity=37.6811594202899, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1787583, Length=329, Percent_Identity=35.8662613981763, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=38.1877022653722, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87081858, Length=467, Percent_Identity=26.1241970021413, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789828, Length=241, Percent_Identity=36.0995850622407, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66199; Mature: 66199

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSLMNAINDALIVTDEHNKIECFNYKAEETFNISHNHLGEKIEGIIFIPDDLKKSDTI
CHHHHHHHHCCEEEEECCCCCEEEEECCCCCEECCCHHHCCCHHCEEEECCCCCCCCCCC
TEGKKESQRRINYYGKTLSVIKTPIIEPTIENQCHLGNYYIFEDISDSVKLKRELSNARS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
SANAMENVLEKAYDGIVMIDHNGIITKFNSAYQQFTGISEQEALGKHVTEVIENTRMHKV
HHHHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LETGKPEIGEIQKIKGCEMVATRVPIYEEGEIVGVLGKVLFRDIKEVKALAERLDAATNE
HHCCCCCCCCHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDYYKGEVRKLKGSKYNFENIVGSSKKIIEAKEMAKIASQSDSTVLIRGESGTGKELFAH
HHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
AIHDGSLRRYGAFIRVNCAAIPENLLEAELFGYEKGAFTGANKEGKPGKFELANGGTIFL
HHCCCCHHHHCCEEEEEEHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEE
DEIGDMPFDMQVKLLRALQEREVQRIGSERVIDLDVRIIASTNRNLEQLIAQDKFREDLY
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCE
YRLNVFNINVPPLREMKDDLEKLINFIIKDLNDEMGLNVNGVSSEANKILNSYHWPGNIR
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCHH
ELKNVLERSMNVAKGNIITKDCIPQYLLTWAGAEEQQNNSNSKSHEINLHNLELRSVVKE
HHHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEHHHHHHHHHH
AEKLAIETALKQTNNNKKKAAELLNIHRSGLYKKLEEYNISDQTT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFDSLMNAINDALIVTDEHNKIECFNYKAEETFNISHNHLGEKIEGIIFIPDDLKKSDTI
CHHHHHHHHCCEEEEECCCCCEEEEECCCCCEECCCHHHCCCHHCEEEECCCCCCCCCCC
TEGKKESQRRINYYGKTLSVIKTPIIEPTIENQCHLGNYYIFEDISDSVKLKRELSNARS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
SANAMENVLEKAYDGIVMIDHNGIITKFNSAYQQFTGISEQEALGKHVTEVIENTRMHKV
HHHHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LETGKPEIGEIQKIKGCEMVATRVPIYEEGEIVGVLGKVLFRDIKEVKALAERLDAATNE
HHCCCCCCCCHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDYYKGEVRKLKGSKYNFENIVGSSKKIIEAKEMAKIASQSDSTVLIRGESGTGKELFAH
HHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
AIHDGSLRRYGAFIRVNCAAIPENLLEAELFGYEKGAFTGANKEGKPGKFELANGGTIFL
HHCCCCHHHHCCEEEEEEHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEE
DEIGDMPFDMQVKLLRALQEREVQRIGSERVIDLDVRIIASTNRNLEQLIAQDKFREDLY
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCE
YRLNVFNINVPPLREMKDDLEKLINFIIKDLNDEMGLNVNGVSSEANKILNSYHWPGNIR
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCHH
ELKNVLERSMNVAKGNIITKDCIPQYLLTWAGAEEQQNNSNSKSHEINLHNLELRSVVKE
HHHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEHHHHHHHHHH
AEKLAIETALKQTNNNKKKAAELLNIHRSGLYKKLEEYNISDQTT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]