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The map label for this gene is gtaB [H]

Identifier: 188587140

GI number: 188587140

Start: 2733632

End: 2734510

Strand: Reverse

Name: gtaB [H]

Synonym: Nther_2537

Alternate gene names: 188587140

Gene position: 2734510-2733632 (Counterclockwise)

Preceding gene: 188587142

Following gene: 188587139

Centisome position: 86.38

GC content: 39.59

Gene sequence:

>879_bases
ATGACAAAAGTAAGAAAAGCGGTGATTCCGGCAGCGGGTCTCGGAACTAGGTTTTTACCTGCTACCAAAGCCCAACCCAA
AGAGATGCTTCCTATACTAGATAAACCGACAATTCAGTATATTATAGAAGAAGCTGTGGAATCTGGAGTAGAAGACATAT
TAATCATCACTGGTAGGGGTAAGCGTGCCATAGAAGATCACTTCGATAGAGCTATAGAGTTGGAAGAAACCTTAGAGGAA
AAAGGGAAACAAGATCTACTAGAAAAAGTAAGAGAGACTAATGAAATAGATATCCATTACATAAGACAGAAAGAACCCTT
AGGACTTGGACATGCAGTGCTTTGTGCTAAGAAGTTCATCGGAAATGAACCTTTTGGTGTTTTACTCGGTGATGACATAG
TCAGAAATGGTGGGGGAGCCCCCTGCTTGAAACAGATGATAGATTTATATGAACAGGAAGATGCTAGTGTCATAGGAGTA
CAGGAAGTGCCTGAACAAGATGTAAGCCGTTATGGTATAGTAGAAAACGGTGCTGAAGTTTCTAAAGGAGCTTATCAGGT
AAATCAATTAATTGAAAAACCTCCGGTAGAGAAAGCACCTTCCAGGTTAGCTATTATGGGAAGGTATGTTATCAGTCCTA
CAATTTTTGACTACCTTGAAAAAACTGGCCCTGGAAGCGGAGGGGAAATTCAGTTGACTGATGCTTTAAATGATCTTGCC
AAGGTAGAAAAGGTCTACGCCTATCCTTTTAAAGGAACTAGATATGATGCTGGAGATTTGTTAGGATATTTAAAGACAAC
GGTAGAATTTGCCTTGGAGCGAGAAGATGTTAAAGATGAATTTAAGGAATACTTGAAGTCTAGGTTTGGTCAAATATAA

Upstream 100 bases:

>100_bases
GGTTAGCTTCTTTTACAATCAGAAGCGGTGTAAAAAGGGCTAACCTTTTTTATATACGTATGTTGCGCACTTGCAACAGT
TTTAAAGGAGGCCGAGATCA

Downstream 100 bases:

>100_bases
TTTAAGTGAAGGTGAGTATAATGTATAAAATATCTGTCATTGGTACAGGGTATGTGGGTTTGTCAACAGGAGTTTGTCTA
TCTGATATGGGTAACCAAGT

Product: UDP-glucose pyrophosphorylase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTKVRKAVIPAAGLGTRFLPATKAQPKEMLPILDKPTIQYIIEEAVESGVEDILIITGRGKRAIEDHFDRAIELEETLEE
KGKQDLLEKVRETNEIDIHYIRQKEPLGLGHAVLCAKKFIGNEPFGVLLGDDIVRNGGGAPCLKQMIDLYEQEDASVIGV
QEVPEQDVSRYGIVENGAEVSKGAYQVNQLIEKPPVEKAPSRLAIMGRYVISPTIFDYLEKTGPGSGGEIQLTDALNDLA
KVEKVYAYPFKGTRYDAGDLLGYLKTTVEFALEREDVKDEFKEYLKSRFGQI

Sequences:

>Translated_292_residues
MTKVRKAVIPAAGLGTRFLPATKAQPKEMLPILDKPTIQYIIEEAVESGVEDILIITGRGKRAIEDHFDRAIELEETLEE
KGKQDLLEKVRETNEIDIHYIRQKEPLGLGHAVLCAKKFIGNEPFGVLLGDDIVRNGGGAPCLKQMIDLYEQEDASVIGV
QEVPEQDVSRYGIVENGAEVSKGAYQVNQLIEKPPVEKAPSRLAIMGRYVISPTIFDYLEKTGPGSGGEIQLTDALNDLA
KVEKVYAYPFKGTRYDAGDLLGYLKTTVEFALEREDVKDEFKEYLKSRFGQI
>Mature_291_residues
TKVRKAVIPAAGLGTRFLPATKAQPKEMLPILDKPTIQYIIEEAVESGVEDILIITGRGKRAIEDHFDRAIELEETLEEK
GKQDLLEKVRETNEIDIHYIRQKEPLGLGHAVLCAKKFIGNEPFGVLLGDDIVRNGGGAPCLKQMIDLYEQEDASVIGVQ
EVPEQDVSRYGIVENGAEVSKGAYQVNQLIEKPPVEKAPSRLAIMGRYVISPTIFDYLEKTGPGSGGEIQLTDALNDLAK
VEKVYAYPFKGTRYDAGDLLGYLKTTVEFALEREDVKDEFKEYLKSRFGQI

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=296, Percent_Identity=44.5945945945946, Blast_Score=240, Evalue=9e-65,
Organism=Escherichia coli, GI1788355, Length=275, Percent_Identity=41.8181818181818, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1790224, Length=230, Percent_Identity=31.7391304347826, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32486; Mature: 32354

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVRKAVIPAAGLGTRFLPATKAQPKEMLPILDKPTIQYIIEEAVESGVEDILIITGRG
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDRAIELEETLEEKGKQDLLEKVRETNEIDIHYIRQKEPLGLGHAVLCAKKFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHH
GNEPFGVLLGDDIVRNGGGAPCLKQMIDLYEQEDASVIGVQEVPEQDVSRYGIVENGAEV
CCCCCEEEECHHHHHCCCCCHHHHHHHHHHHHCCCCEECHHHCCHHHHHHCCCCCCCCHH
SKGAYQVNQLIEKPPVEKAPSRLAIMGRYVISPTIFDYLEKTGPGSGGEIQLTDALNDLA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
KVEKVYAYPFKGTRYDAGDLLGYLKTTVEFALEREDVKDEFKEYLKSRFGQI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKVRKAVIPAAGLGTRFLPATKAQPKEMLPILDKPTIQYIIEEAVESGVEDILIITGRG
CCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDRAIELEETLEEKGKQDLLEKVRETNEIDIHYIRQKEPLGLGHAVLCAKKFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHH
GNEPFGVLLGDDIVRNGGGAPCLKQMIDLYEQEDASVIGVQEVPEQDVSRYGIVENGAEV
CCCCCEEEECHHHHHCCCCCHHHHHHHHHHHHCCCCEECHHHCCHHHHHHCCCCCCCCHH
SKGAYQVNQLIEKPPVEKAPSRLAIMGRYVISPTIFDYLEKTGPGSGGEIQLTDALNDLA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
KVEKVYAYPFKGTRYDAGDLLGYLKTTVEFALEREDVKDEFKEYLKSRFGQI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]