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The map label for this gene is mcpC [H]

Identifier: 188587055

GI number: 188587055

Start: 2625832

End: 2627145

Strand: Reverse

Name: mcpC [H]

Synonym: Nther_2447

Alternate gene names: 188587055

Gene position: 2627145-2625832 (Counterclockwise)

Preceding gene: 188587056

Following gene: 188587051

Centisome position: 82.99

GC content: 39.57

Gene sequence:

>1314_bases
ATGATTATTTGGAGAAGAGTATGGGAAGAAAAAGACAAGGTCATTGACACAGATGATCATTATCTAGGCAGTTTGTATCT
TGAAGAATTGGACTGGGTTTTATTTTATGATGTTCCCCATGAAGCTGTTTTAGGGGATGTTGAGTTCACTCAGGCCGTAA
TAATGACTGCTCTGATATTAACAGTACTAATAGCTTTAATAATGTCTTATTTTGTCAATAGGGTAGCTGGAAAACCAATT
GCAGAACTTACAGAGCTTATTAGCCGATTAGGTGACTATGATTTCACCTATAATGATGATGCTGAATCAATGAAATATCT
AAAGAGAGGCGACGAGATTGGCGATATAACCAGAGCCGTGACAGGTATGCGACAAAATGTAGCAGAATTACTTCAGGGAA
TTGAACAAAAATCAGAACAAGTGGCTTCTTCCTCTCAAGAATTAACTGCTAACAGCTCAGAAAATACCAATGCTGCCAAT
GAAGTTTCCCGGGCAGTTGAAGATATTGCCAGTGGAGCAAGTAATCAGGCTGAAAGTACAGAACAGGCTTCGGCCAGTAC
TGAGGAATTGGGCAAAATTGTGGAGAAAGAACAAGCCCATGTCAGGCAGTTAAATGAAGTTGTTGAAGAAGTAACTGAAT
TGAAAAATCAGGGTTCACAAGCCGTTGAACAGTTGACAAGCAAGACTGAAGAGAGTAATTCTTCAGCACAAAACATAGCT
AGAATCATCAATGAAACTAAAAATAGCGCCGATAACATTGAAAAAGCCAGTAATACCATTAGAGATATTGCAGAACAGAC
CAATTTACTGGCATTAAATGCCAGTATTGAAGCAGCCAGGGCGGGTGAAGCAGGATCAGGTTTTTCCGTGGTGGCCAATG
AAATCAGGAACCTGGCGGAGAACTCCAATAAATATTCAGAGGAGATTTCACAAATAGTTGCCGATTTAATGGATAAATCT
AATACTGCCGTTAAAACAATGGATGAAGTTAGTGGAACAGTCAAAGAACAGACCGAATACGTGAAAGCAGCCGATGCAAA
ATTTGAAGGAATTGCAGAGGGTATCGAAAAGGTTAGACAAGTTGTTGAAAGTTTAAATGAAACCGGGTCACAGATGCAGG
AAAAGAAACAAGAAATCATAGATACTCTTCAGAGTTTATCGGCTATAGCTCAGGAGAATTCCTCCAGTACTGAAGAGATA
TCTTCATCGGTTGAGGAACAGACGGCGTCCATGGAAGAAATAGCTCGTTCTAGTGAGCATTTATCCAAGTTAGCCCAGGA
AATGCAAGAAGAAGCCTCTAAATTTAAATACTAA

Upstream 100 bases:

>100_bases
GAAGAGTATGTTGGCTCTGTATATATTGTTGATAGAGGTGGAACTATAGCTGCTGGTACAGAAGGAGAATCTAATAATGA
TAGAATAGAGACGTTAGTTG

Downstream 100 bases:

>100_bases
TTGGAGAATTCGTCACGCACTCTCGTGCCTTTAGTTATGAGAGGTTCACACAGGATGAACTGGATTTAAGACATTAAGAT
AAGCCCCGGGGCATATCACA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MIIWRRVWEEKDKVIDTDDHYLGSLYLEELDWVLFYDVPHEAVLGDVEFTQAVIMTALILTVLIALIMSYFVNRVAGKPI
AELTELISRLGDYDFTYNDDAESMKYLKRGDEIGDITRAVTGMRQNVAELLQGIEQKSEQVASSSQELTANSSENTNAAN
EVSRAVEDIASGASNQAESTEQASASTEELGKIVEKEQAHVRQLNEVVEEVTELKNQGSQAVEQLTSKTEESNSSAQNIA
RIINETKNSADNIEKASNTIRDIAEQTNLLALNASIEAARAGEAGSGFSVVANEIRNLAENSNKYSEEISQIVADLMDKS
NTAVKTMDEVSGTVKEQTEYVKAADAKFEGIAEGIEKVRQVVESLNETGSQMQEKKQEIIDTLQSLSAIAQENSSSTEEI
SSSVEEQTASMEEIARSSEHLSKLAQEMQEEASKFKY

Sequences:

>Translated_437_residues
MIIWRRVWEEKDKVIDTDDHYLGSLYLEELDWVLFYDVPHEAVLGDVEFTQAVIMTALILTVLIALIMSYFVNRVAGKPI
AELTELISRLGDYDFTYNDDAESMKYLKRGDEIGDITRAVTGMRQNVAELLQGIEQKSEQVASSSQELTANSSENTNAAN
EVSRAVEDIASGASNQAESTEQASASTEELGKIVEKEQAHVRQLNEVVEEVTELKNQGSQAVEQLTSKTEESNSSAQNIA
RIINETKNSADNIEKASNTIRDIAEQTNLLALNASIEAARAGEAGSGFSVVANEIRNLAENSNKYSEEISQIVADLMDKS
NTAVKTMDEVSGTVKEQTEYVKAADAKFEGIAEGIEKVRQVVESLNETGSQMQEKKQEIIDTLQSLSAIAQENSSSTEEI
SSSVEEQTASMEEIARSSEHLSKLAQEMQEEASKFKY
>Mature_437_residues
MIIWRRVWEEKDKVIDTDDHYLGSLYLEELDWVLFYDVPHEAVLGDVEFTQAVIMTALILTVLIALIMSYFVNRVAGKPI
AELTELISRLGDYDFTYNDDAESMKYLKRGDEIGDITRAVTGMRQNVAELLQGIEQKSEQVASSSQELTANSSENTNAAN
EVSRAVEDIASGASNQAESTEQASASTEELGKIVEKEQAHVRQLNEVVEEVTELKNQGSQAVEQLTSKTEESNSSAQNIA
RIINETKNSADNIEKASNTIRDIAEQTNLLALNASIEAARAGEAGSGFSVVANEIRNLAENSNKYSEEISQIVADLMDKS
NTAVKTMDEVSGTVKEQTEYVKAADAKFEGIAEGIEKVRQVVESLNETGSQMQEKKQEIIDTLQSLSAIAQENSSSTEEI
SSSVEEQTASMEEIARSSEHLSKLAQEMQEEASKFKY

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=370, Percent_Identity=25.4054054054054, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=27.4576271186441, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367378, Length=335, Percent_Identity=27.4626865671642, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=30.5882352941176, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789453, Length=364, Percent_Identity=24.7252747252747, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 48180; Mature: 48180

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWRRVWEEKDKVIDTDDHYLGSLYLEELDWVLFYDVPHEAVLGDVEFTQAVIMTALIL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECCCHHHHHCHHHHHHHHHHHHHHH
TVLIALIMSYFVNRVAGKPIAELTELISRLGDYDFTYNDDAESMKYLKRGDEIGDITRAV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHH
TGMRQNVAELLQGIEQKSEQVASSSQELTANSSENTNAANEVSRAVEDIASGASNQAEST
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
EQASASTEELGKIVEKEQAHVRQLNEVVEEVTELKNQGSQAVEQLTSKTEESNSSAQNIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHH
RIINETKNSADNIEKASNTIRDIAEQTNLLALNASIEAARAGEAGSGFSVVANEIRNLAE
HHHHHHHCHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHH
NSNKYSEEISQIVADLMDKSNTAVKTMDEVSGTVKEQTEYVKAADAKFEGIAEGIEKVRQ
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVESLNETGSQMQEKKQEIIDTLQSLSAIAQENSSSTEEISSSVEEQTASMEEIARSSEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSKLAQEMQEEASKFKY
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIWRRVWEEKDKVIDTDDHYLGSLYLEELDWVLFYDVPHEAVLGDVEFTQAVIMTALIL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECCCHHHHHCHHHHHHHHHHHHHHH
TVLIALIMSYFVNRVAGKPIAELTELISRLGDYDFTYNDDAESMKYLKRGDEIGDITRAV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHH
TGMRQNVAELLQGIEQKSEQVASSSQELTANSSENTNAANEVSRAVEDIASGASNQAEST
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
EQASASTEELGKIVEKEQAHVRQLNEVVEEVTELKNQGSQAVEQLTSKTEESNSSAQNIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHH
RIINETKNSADNIEKASNTIRDIAEQTNLLALNASIEAARAGEAGSGFSVVANEIRNLAE
HHHHHHHCHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHH
NSNKYSEEISQIVADLMDKSNTAVKTMDEVSGTVKEQTEYVKAADAKFEGIAEGIEKVRQ
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVESLNETGSQMQEKKQEIIDTLQSLSAIAQENSSSTEEISSSVEEQTASMEEIARSSEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSKLAQEMQEEASKFKY
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]