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The map label for this gene is ttdA [C]

Identifier: 188587006

GI number: 188587006

Start: 2562001

End: 2562843

Strand: Reverse

Name: ttdA [C]

Synonym: Nther_2398

Alternate gene names: 188587006

Gene position: 2562843-2562001 (Counterclockwise)

Preceding gene: 188587007

Following gene: 188587005

Centisome position: 80.96

GC content: 43.42

Gene sequence:

>843_bases
TTGCGTAAAATCCATGTTTCCGAGATTACCAGGAGTGTAAAAGAGATGTTTATTGAAGCCAATCAGTTCCTGGGTGAAGA
TGTGTCCCAGGCTTTAAAAGATGGTCTGGCAGGGGAAGAATCTCCTGTAGGTCAAGAAGTATTAAAACAACTTCTTAAAA
ATGCGGAAATAGCCAAGGAACAAGAGGTTCCGATCTGTCAGGACACTGGTACCAGTGTGGTTTTTATGGATATCGGCCAG
GATGTACACTTTACAGGAGGTGAACTAACCGAAGCAGTTAATCAAGGAGTTAGAGAAGCTTATCTGAGAGCTTATTTGAG
AACCTCTATGGTAAAGGATCCTTTAAATAGAGAAAACACTGGTGATAATACTCCGGCAATTATTCATACCAGAATTGTTC
CTGGAGATAAAGTGAAGCTAGATGTGGCGCCCAAGGGCGGTGGCAGTGAAAATATGAGCACTTTGAAAATGCTGACACCT
TCCCAGGGAAAAGAGGGGATTATTGACTTTGTGGTTAGAAGTGTGGAGCAAGCTGGACCCAATGCATGTCCACCTTTTAT
TATTGGTGTTGGCCTTGGCGGAAACTTTGAAAAAGTGGCTTATCTATCGAAAAAAGCATTGCTCAGGCCTGTGGGCAGTC
GTCATCCTGAAGATCAGTATGCCCAGCTGGAGGAAGAACTGTTAGAACAGATTAATAACCTGGGAATTGGTCCTCAAGGC
TTTGGAGGCAGGACTACTGCTCTGGATGTGCATATAGAAAAATATCCTGTTCATCTAACAAGCATTCCTGTGGCTGTTAA
TATAAGTTGTCATGCCACCAGGCATGCTCATAGGGAGATCTAG

Upstream 100 bases:

>100_bases
AGGCTGCAATAGATTCTGGGCTAAATCGAAAGGATATCAATTCAATATAGTTCATGCTATTATAAGCCATAAAGCAAACA
TAAGCTAAGGAGGAATCTCT

Downstream 100 bases:

>100_bases
TATCATAGAAAGAGGTGATGTGATGGATTAAAACTTGTCGATATTTTTATTCTTACATTGCGTTCAACAAAACTAAATAG
AGAAGAGGAGAGATTAAGTG

Product: fumarase alpha subunit

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRKIHVSEITRSVKEMFIEANQFLGEDVSQALKDGLAGEESPVGQEVLKQLLKNAEIAKEQEVPICQDTGTSVVFMDIGQ
DVHFTGGELTEAVNQGVREAYLRAYLRTSMVKDPLNRENTGDNTPAIIHTRIVPGDKVKLDVAPKGGGSENMSTLKMLTP
SQGKEGIIDFVVRSVEQAGPNACPPFIIGVGLGGNFEKVAYLSKKALLRPVGSRHPEDQYAQLEEELLEQINNLGIGPQG
FGGRTTALDVHIEKYPVHLTSIPVAVNISCHATRHAHREI

Sequences:

>Translated_280_residues
MRKIHVSEITRSVKEMFIEANQFLGEDVSQALKDGLAGEESPVGQEVLKQLLKNAEIAKEQEVPICQDTGTSVVFMDIGQ
DVHFTGGELTEAVNQGVREAYLRAYLRTSMVKDPLNRENTGDNTPAIIHTRIVPGDKVKLDVAPKGGGSENMSTLKMLTP
SQGKEGIIDFVVRSVEQAGPNACPPFIIGVGLGGNFEKVAYLSKKALLRPVGSRHPEDQYAQLEEELLEQINNLGIGPQG
FGGRTTALDVHIEKYPVHLTSIPVAVNISCHATRHAHREI
>Mature_280_residues
MRKIHVSEITRSVKEMFIEANQFLGEDVSQALKDGLAGEESPVGQEVLKQLLKNAEIAKEQEVPICQDTGTSVVFMDIGQ
DVHFTGGELTEAVNQGVREAYLRAYLRTSMVKDPLNRENTGDNTPAIIHTRIVPGDKVKLDVAPKGGGSENMSTLKMLTP
SQGKEGIIDFVVRSVEQAGPNACPPFIIGVGLGGNFEKVAYLSKKALLRPVGSRHPEDQYAQLEEELLEQINNLGIGPQG
FGGRTTALDVHIEKYPVHLTSIPVAVNISCHATRHAHREI

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=272, Percent_Identity=36.7647058823529, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1790564, Length=257, Percent_Identity=36.5758754863813, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787897, Length=297, Percent_Identity=33.6700336700337, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30510; Mature: 30510

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIHVSEITRSVKEMFIEANQFLGEDVSQALKDGLAGEESPVGQEVLKQLLKNAEIAKE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHH
QEVPICQDTGTSVVFMDIGQDVHFTGGELTEAVNQGVREAYLRAYLRTSMVKDPLNRENT
CCCCCCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDNTPAIIHTRIVPGDKVKLDVAPKGGGSENMSTLKMLTPSQGKEGIIDFVVRSVEQAGP
CCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
NACPPFIIGVGLGGNFEKVAYLSKKALLRPVGSRHPEDQYAQLEEELLEQINNLGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FGGRTTALDVHIEKYPVHLTSIPVAVNISCHATRHAHREI
CCCCCEEEEEEEEECCEEEEECCEEEEEEEHHHHHHHCCC
>Mature Secondary Structure
MRKIHVSEITRSVKEMFIEANQFLGEDVSQALKDGLAGEESPVGQEVLKQLLKNAEIAKE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHH
QEVPICQDTGTSVVFMDIGQDVHFTGGELTEAVNQGVREAYLRAYLRTSMVKDPLNRENT
CCCCCCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDNTPAIIHTRIVPGDKVKLDVAPKGGGSENMSTLKMLTPSQGKEGIIDFVVRSVEQAGP
CCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
NACPPFIIGVGLGGNFEKVAYLSKKALLRPVGSRHPEDQYAQLEEELLEQINNLGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FGGRTTALDVHIEKYPVHLTSIPVAVNISCHATRHAHREI
CCCCCEEEEEEEEECCEEEEECCEEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]