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The map label for this gene is sucC [H]

Identifier: 188587004

GI number: 188587004

Start: 2560119

End: 2561246

Strand: Reverse

Name: sucC [H]

Synonym: Nther_2396

Alternate gene names: 188587004

Gene position: 2561246-2560119 (Counterclockwise)

Preceding gene: 188587005

Following gene: 188587003

Centisome position: 80.91

GC content: 42.46

Gene sequence:

>1128_bases
ATGAAATTATATGAATATATGGCTAAGAAATTGATGAATCAATGTGGTATTTCCGTACCCAGGGGAGAAGCAGCATTTTC
CGCTCAAGAGGTGGAACAAAAATTTACTGGTTTGGACTCTCCTGCGGTAATAAAAAGTCAGGTCCTTGTGGGTGGACGTG
GCAAGGCAGGGGGGATTAAATTTGCGGATACCCCCCAGGAAGCCAGAAAAGTTAGTAAGGAATTATTTAATATGCAAATA
AAGGGAGAGCAGGTAACAGGAGTTTTAGTGGAAGAACAGCTAGATATATCCAGTGAACTTTATCTTAGTATTACTGTGGA
TACGGGAACTAAAAAACCACTAATTATGGCTTCTACCCAGGGTGGTGTAGATATTGAAGAGGTCTCTGATGATTTGATTG
TAAAGCGTCATATTGAGCCAGACTGGGGCGTCCTTCCTTATCTTTGTAGAGAAATTACAGATCAACTTAATTTACCAGGG
GAAGCTAGCAAACAAGTTTCTGCCATCATTTCAAAACTCTATGACACCTTTAAAACTTACGACGCAGAACTGGTTGAAAT
CAATCCCTTGGTGATTACTGAGGATAATCGTGTAATAGCAGCTGATGGAAAAATGACTATAGATGATGACGCCATGTACA
GACAAGATGAATTGCCTCGGGTGTCAGAAAAGACATCCCTAGAACAGCAAGTTGAGAAAATCGGGCTATCCTTTGTAGAA
CTGGAAGGAGATATAGCGATTATGGCTAATGGCGCTGGAATGGCCATGGCTACAGTAGACGTGATAGAACAGTACGGTGG
GAAAGCTGCCAACTTCCTAGATGCCGGGGGAGGAGCCAGTGTAGAACCGACAAAAAAAGCTCTGGAGTTACTTCTCAATA
CGGATCCCCGGGCTGTAATAATTAATATTTTTGGTGGTATTACCAGATGTGATGATGTGGCCAATGCCCTGGTCCAGGTA
AAACAAGATATGGGCATTAAAGTACCCTTGGTAATTCGTTTGATAGGGACTAAAGACGAGGAAGCTGTCAAAATTTTAGG
ACAACACGGTATTTCCGCCTATCAAGATATGGGAGAGGCGGCCAAAAAAGCTGTTGAATTAGCTGCTGAGGGAGGAGTTG
GTGTATAA

Upstream 100 bases:

>100_bases
GCTAATGATATCTATGGCAATGACCTGTACCAACAGGGCAAGAATAGGTATGCCAAGTAGCATGGTTTCATATTTATCAC
GATAGTGGGAGGTTTGGGAT

Downstream 100 bases:

>100_bases
TGGCTATTTTACTGGATAAAAATAGTAAAATTTTGGTGCAGGGCATCACCGGATATCAGGGACGGTTTCACACCAGGCAG
ATGCTAGAATACGGAAGTAA

Product: succinyl-CoA synthetase, beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKLYEYMAKKLMNQCGISVPRGEAAFSAQEVEQKFTGLDSPAVIKSQVLVGGRGKAGGIKFADTPQEARKVSKELFNMQI
KGEQVTGVLVEEQLDISSELYLSITVDTGTKKPLIMASTQGGVDIEEVSDDLIVKRHIEPDWGVLPYLCREITDQLNLPG
EASKQVSAIISKLYDTFKTYDAELVEINPLVITEDNRVIAADGKMTIDDDAMYRQDELPRVSEKTSLEQQVEKIGLSFVE
LEGDIAIMANGAGMAMATVDVIEQYGGKAANFLDAGGGASVEPTKKALELLLNTDPRAVIINIFGGITRCDDVANALVQV
KQDMGIKVPLVIRLIGTKDEEAVKILGQHGISAYQDMGEAAKKAVELAAEGGVGV

Sequences:

>Translated_375_residues
MKLYEYMAKKLMNQCGISVPRGEAAFSAQEVEQKFTGLDSPAVIKSQVLVGGRGKAGGIKFADTPQEARKVSKELFNMQI
KGEQVTGVLVEEQLDISSELYLSITVDTGTKKPLIMASTQGGVDIEEVSDDLIVKRHIEPDWGVLPYLCREITDQLNLPG
EASKQVSAIISKLYDTFKTYDAELVEINPLVITEDNRVIAADGKMTIDDDAMYRQDELPRVSEKTSLEQQVEKIGLSFVE
LEGDIAIMANGAGMAMATVDVIEQYGGKAANFLDAGGGASVEPTKKALELLLNTDPRAVIINIFGGITRCDDVANALVQV
KQDMGIKVPLVIRLIGTKDEEAVKILGQHGISAYQDMGEAAKKAVELAAEGGVGV
>Mature_375_residues
MKLYEYMAKKLMNQCGISVPRGEAAFSAQEVEQKFTGLDSPAVIKSQVLVGGRGKAGGIKFADTPQEARKVSKELFNMQI
KGEQVTGVLVEEQLDISSELYLSITVDTGTKKPLIMASTQGGVDIEEVSDDLIVKRHIEPDWGVLPYLCREITDQLNLPG
EASKQVSAIISKLYDTFKTYDAELVEINPLVITEDNRVIAADGKMTIDDDAMYRQDELPRVSEKTSLEQQVEKIGLSFVE
LEGDIAIMANGAGMAMATVDVIEQYGGKAANFLDAGGGASVEPTKKALELLLNTDPRAVIINIFGGITRCDDVANALVQV
KQDMGIKVPLVIRLIGTKDEEAVKILGQHGISAYQDMGEAAKKAVELAAEGGVGV

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=36.6412213740458, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI157779135, Length=374, Percent_Identity=37.9679144385027, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI294862256, Length=360, Percent_Identity=37.7777777777778, Blast_Score=219, Evalue=3e-57,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=38.1443298969072, Blast_Score=241, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17567829, Length=398, Percent_Identity=36.9346733668342, Blast_Score=231, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=36.2244897959184, Blast_Score=214, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=39.0862944162437, Blast_Score=262, Evalue=6e-71,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=35.1145038167939, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=35.1145038167939, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI281361397, Length=396, Percent_Identity=35.3535353535354, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI281361395, Length=396, Percent_Identity=35.3535353535354, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=33.7595907928389, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 40439; Mature: 40439

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYEYMAKKLMNQCGISVPRGEAAFSAQEVEQKFTGLDSPAVIKSQVLVGGRGKAGGIK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCCCCEE
FADTPQEARKVSKELFNMQIKGEQVTGVLVEEQLDISSELYLSITVDTGTKKPLIMASTQ
CCCCHHHHHHHHHHHHCEEECCCEEEEEEEHHHCCCCCEEEEEEEEECCCCCCEEEEECC
GGVDIEEVSDDLIVKRHIEPDWGVLPYLCREITDQLNLPGEASKQVSAIISKLYDTFKTY
CCCCHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
DAELVEINPLVITEDNRVIAADGKMTIDDDAMYRQDELPRVSEKTSLEQQVEKIGLSFVE
CCEEEEECCEEEECCCEEEEECCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCEEEE
LEGDIAIMANGAGMAMATVDVIEQYGGKAANFLDAGGGASVEPTKKALELLLNTDPRAVI
ECCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCEEE
INIFGGITRCDDVANALVQVKQDMGIKVPLVIRLIGTKDEEAVKILGQHGISAYQDMGEA
EEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHH
AKKAVELAAEGGVGV
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLYEYMAKKLMNQCGISVPRGEAAFSAQEVEQKFTGLDSPAVIKSQVLVGGRGKAGGIK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCCCCEE
FADTPQEARKVSKELFNMQIKGEQVTGVLVEEQLDISSELYLSITVDTGTKKPLIMASTQ
CCCCHHHHHHHHHHHHCEEECCCEEEEEEEHHHCCCCCEEEEEEEEECCCCCCEEEEECC
GGVDIEEVSDDLIVKRHIEPDWGVLPYLCREITDQLNLPGEASKQVSAIISKLYDTFKTY
CCCCHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
DAELVEINPLVITEDNRVIAADGKMTIDDDAMYRQDELPRVSEKTSLEQQVEKIGLSFVE
CCEEEEECCEEEECCCEEEEECCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCEEEE
LEGDIAIMANGAGMAMATVDVIEQYGGKAANFLDAGGGASVEPTKKALELLLNTDPRAVI
ECCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCEEE
INIFGGITRCDDVANALVQVKQDMGIKVPLVIRLIGTKDEEAVKILGQHGISAYQDMGEA
EEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHH
AKKAVELAAEGGVGV
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA