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The map label for this gene is dppB [H]

Identifier: 188586997

GI number: 188586997

Start: 2553182

End: 2554171

Strand: Direct

Name: dppB [H]

Synonym: Nther_2389

Alternate gene names: 188586997

Gene position: 2553182-2554171 (Clockwise)

Preceding gene: 188586996

Following gene: 188586998

Centisome position: 80.66

GC content: 42.53

Gene sequence:

>990_bases
ATGGTGAAAAATTTGGGCTTTAGGCGATTTGTCTTGCGTAGAATCGGTCAAGTAATCATCAGCTTATTCATTGTTGCCAC
CATTGTATTTTTTCTCTTTCGATTATTACCCGGTGACCCGACAGCAGCCATGATGCAGCCCGAAATGTCCTCAGAAGCCC
AAGAAATGATTCGGGAAAGATTTGGTCTTGACCGCCCTCTTCATGAACAGTATTTAGCATATATGGTTAACTTGCTTCAA
GGGGACTTTGGTATATCCTTTCACTACAGACTACCCGTTAGCCAAGTTATAGGTACTTACATTCTGAACACCCTTTGGCT
AATGTTTTCAGCTATTGCAGTTGCCTACATTGGAGGAGTCCTAATAGGTGGGTTAATGTCCTGGTATCGCGGATCAAGAC
TAGAAACTTTCTTGAGTGGTGGTGTACTATTCTGTCGGTCTTTACCACCTTTTTTCTTGGGAATGGTGGGAATAATGGTT
TTTAGCTTTTATTTTGAATTACTCCCCCATTCTGGTATGAGGTCCCCTGGAGCTAATCCAGTGGGTTTTGTAGAAACTTA
TTTAAATTTAGACTTCCTCTATCATTTGATTCTGCCAGTAGCCATGTCGAGTTTATATTATCTAGCTCGTCCCACTCTGA
TTATGAGAAATAATATGCTGGAATTGAGAGGAGCCGATTTTGTTGAACTAGCAAGAGCCAAGGGGCTCAGACAATCTCGG
GTAATCTACCTTCATGCAGCCAGGAATGCAATTTTACCTGTAATAACTAATTTAGCTCTCTTCCTGGGAATGGCCATTGG
AGCAGCAGTAGCCGTTGAATACGTTTTTGGATGGCCAGGCCTCGGCCGTGAAATGGTCAGGGCTGCACAACTCAGGGATT
ATCCCCTAGCCCAGGCTTGTTTTCTAATGTTAGCAGCTAAAGTAATGGTACTGAATCTGTTAGTAGATATACTCTATGGC
TATCTAGATCCCAGGATCACCTATGAATAA

Upstream 100 bases:

>100_bases
TCTTATCCTGTTAATCAATATAATCAATCCATTTAAGCTGCTAATACTTTTAAAAGGATGATTTATTTATTTTTATCTAG
ACCGTAAGTTGTGAGAAAGG

Downstream 100 bases:

>100_bases
AGGGGGTTTCAAATTTAATGAATAAAGAAATTGAATCTCAATTACAGGAACATGATGCTCCTAGTTTTAAAAGTAAAGTA
TCTTCATTGGCCTATTTCAT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MVKNLGFRRFVLRRIGQVIISLFIVATIVFFLFRLLPGDPTAAMMQPEMSSEAQEMIRERFGLDRPLHEQYLAYMVNLLQ
GDFGISFHYRLPVSQVIGTYILNTLWLMFSAIAVAYIGGVLIGGLMSWYRGSRLETFLSGGVLFCRSLPPFFLGMVGIMV
FSFYFELLPHSGMRSPGANPVGFVETYLNLDFLYHLILPVAMSSLYYLARPTLIMRNNMLELRGADFVELARAKGLRQSR
VIYLHAARNAILPVITNLALFLGMAIGAAVAVEYVFGWPGLGREMVRAAQLRDYPLAQACFLMLAAKVMVLNLLVDILYG
YLDPRITYE

Sequences:

>Translated_329_residues
MVKNLGFRRFVLRRIGQVIISLFIVATIVFFLFRLLPGDPTAAMMQPEMSSEAQEMIRERFGLDRPLHEQYLAYMVNLLQ
GDFGISFHYRLPVSQVIGTYILNTLWLMFSAIAVAYIGGVLIGGLMSWYRGSRLETFLSGGVLFCRSLPPFFLGMVGIMV
FSFYFELLPHSGMRSPGANPVGFVETYLNLDFLYHLILPVAMSSLYYLARPTLIMRNNMLELRGADFVELARAKGLRQSR
VIYLHAARNAILPVITNLALFLGMAIGAAVAVEYVFGWPGLGREMVRAAQLRDYPLAQACFLMLAAKVMVLNLLVDILYG
YLDPRITYE
>Mature_329_residues
MVKNLGFRRFVLRRIGQVIISLFIVATIVFFLFRLLPGDPTAAMMQPEMSSEAQEMIRERFGLDRPLHEQYLAYMVNLLQ
GDFGISFHYRLPVSQVIGTYILNTLWLMFSAIAVAYIGGVLIGGLMSWYRGSRLETFLSGGVLFCRSLPPFFLGMVGIMV
FSFYFELLPHSGMRSPGANPVGFVETYLNLDFLYHLILPVAMSSLYYLARPTLIMRNNMLELRGADFVELARAKGLRQSR
VIYLHAARNAILPVITNLALFLGMAIGAAVAVEYVFGWPGLGREMVRAAQLRDYPLAQACFLMLAAKVMVLNLLVDILYG
YLDPRITYE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=36.9047619047619, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787053, Length=325, Percent_Identity=34.7692307692308, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=31.3664596273292, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789888, Length=326, Percent_Identity=33.1288343558282, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=31.0240963855422, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=26.5927977839335, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=25.7352941176471, Blast_Score=88, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37129; Mature: 37129

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNLGFRRFVLRRIGQVIISLFIVATIVFFLFRLLPGDPTAAMMQPEMSSEAQEMIRER
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHH
FGLDRPLHEQYLAYMVNLLQGDFGISFHYRLPVSQVIGTYILNTLWLMFSAIAVAYIGGV
HCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGGLMSWYRGSRLETFLSGGVLFCRSLPPFFLGMVGIMVFSFYFELLPHSGMRSPGANP
HHHHHHHHHCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VGFVETYLNLDFLYHLILPVAMSSLYYLARPTLIMRNNMLELRGADFVELARAKGLRQSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCHHHHHHHHCCCCCCC
VIYLHAARNAILPVITNLALFLGMAIGAAVAVEYVFGWPGLGREMVRAAQLRDYPLAQAC
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHH
FLMLAAKVMVLNLLVDILYGYLDPRITYE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVKNLGFRRFVLRRIGQVIISLFIVATIVFFLFRLLPGDPTAAMMQPEMSSEAQEMIRER
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHH
FGLDRPLHEQYLAYMVNLLQGDFGISFHYRLPVSQVIGTYILNTLWLMFSAIAVAYIGGV
HCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGGLMSWYRGSRLETFLSGGVLFCRSLPPFFLGMVGIMVFSFYFELLPHSGMRSPGANP
HHHHHHHHHCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VGFVETYLNLDFLYHLILPVAMSSLYYLARPTLIMRNNMLELRGADFVELARAKGLRQSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCHHHHHHHHCCCCCCC
VIYLHAARNAILPVITNLALFLGMAIGAAVAVEYVFGWPGLGREMVRAAQLRDYPLAQAC
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHH
FLMLAAKVMVLNLLVDILYGYLDPRITYE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]