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The map label for this gene is namA [H]

Identifier: 188586961

GI number: 188586961

Start: 2504245

End: 2505240

Strand: Reverse

Name: namA [H]

Synonym: Nther_2353

Alternate gene names: 188586961

Gene position: 2505240-2504245 (Counterclockwise)

Preceding gene: 188586962

Following gene: 188586960

Centisome position: 79.14

GC content: 43.47

Gene sequence:

>996_bases
GTGACTGCGCTCTTTGAGCCCAAAAAAGTAAAAGATTTTCTTTTTAAGAATAGAATTATTATGCCGCCAATGGTGAGTGA
GAAAGCAACTGAACAAGGACAAGTCACAGATAAAAATGTCGAATATTATTTAGACAGGGCAAAAGAGGGCCTGGCAGGGG
TGATAGTGGAACCTGCATTTATTTCTGAAAATGGACGATGTAGTAGACATCAACTGTCAGCTGCTGATGACGATAAGGTT
GAAGGTTTAAGTCGCTTGGCATCATCCATAAAAAACACTGGAGCCGTTGCCATACTCCAGCTAAATCATGGCGGAGCAAA
GGCGTATTCCAAAGATAAAAGCGAACTTTTATCACCTTCTGGTGTACTAGCCCCTAATGTTACACAGGAAGTAACCCCCC
GCCAGATGACTTTAGGGGAGATAGCCCAAGTTAAGGCAGATTTTATCAAAGCTACGGAACGGGCTATGGAGGCTGGTTTT
GATGGTGTAGAAATTCATGGAGCCCATGGGTTTTTGTTAAATCAATTTAATTCACCTTTGACGAATTTTCGCCAGGATAA
ATACGGAGGTTCTCGAAAAAATCGAGCCCGACTCTCTCTGGAAGTAGCCAGTGATCTTAAAGAGGTTGTGGGAAATAAGT
TACTCCTGTATCGTTTAGGCGCTACGGATGGATATGATAAAGGGTTGACTATGCCCGATGCCATTTGGATAGCAAAAGAG
CTAGTCCGAAATGGTGTAGATATTATAGACGTTTCCGGTGGTCATGGGGGATATCGTGGTCACACAAGGAGTCAAGGCTA
CTTTGTTCCCATAGCTGTGGAAATTAAACAGAACCTGACTCAACCTGTCATGGTTGCAGGCGGCATCAGCAGCCCACAAT
ATGCCAATGAGGTAATAGAAGAAGAAGGCCTTGATTTTGTAGGAGTGGGAAGAGCCCTGTTATCTAGGCCTGACTGGCCT
TATATGGCTAAGCAAGAATTGATTAATCGTAAGTAA

Upstream 100 bases:

>100_bases
GGAGATTAAACTCAACTTGTAGAATACACAAACGCGAAAGGTTTTGTGATATTTTTCTCAAGGAAGATTTAAAATTTGAA
AAAAATTGGGGGGTTAACAA

Downstream 100 bases:

>100_bases
ATAGATAGATATAGATAAGGTCCGCAGTAGGGCCTTTTTTTAAATGTAGGTGCTATTATATTTCAGTATTAATACAGTAA
AGTCTTCATGTCAAATTTTC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTALFEPKKVKDFLFKNRIIMPPMVSEKATEQGQVTDKNVEYYLDRAKEGLAGVIVEPAFISENGRCSRHQLSAADDDKV
EGLSRLASSIKNTGAVAILQLNHGGAKAYSKDKSELLSPSGVLAPNVTQEVTPRQMTLGEIAQVKADFIKATERAMEAGF
DGVEIHGAHGFLLNQFNSPLTNFRQDKYGGSRKNRARLSLEVASDLKEVVGNKLLLYRLGATDGYDKGLTMPDAIWIAKE
LVRNGVDIIDVSGGHGGYRGHTRSQGYFVPIAVEIKQNLTQPVMVAGGISSPQYANEVIEEEGLDFVGVGRALLSRPDWP
YMAKQELINRK

Sequences:

>Translated_331_residues
MTALFEPKKVKDFLFKNRIIMPPMVSEKATEQGQVTDKNVEYYLDRAKEGLAGVIVEPAFISENGRCSRHQLSAADDDKV
EGLSRLASSIKNTGAVAILQLNHGGAKAYSKDKSELLSPSGVLAPNVTQEVTPRQMTLGEIAQVKADFIKATERAMEAGF
DGVEIHGAHGFLLNQFNSPLTNFRQDKYGGSRKNRARLSLEVASDLKEVVGNKLLLYRLGATDGYDKGLTMPDAIWIAKE
LVRNGVDIIDVSGGHGGYRGHTRSQGYFVPIAVEIKQNLTQPVMVAGGISSPQYANEVIEEEGLDFVGVGRALLSRPDWP
YMAKQELINRK
>Mature_330_residues
TALFEPKKVKDFLFKNRIIMPPMVSEKATEQGQVTDKNVEYYLDRAKEGLAGVIVEPAFISENGRCSRHQLSAADDDKVE
GLSRLASSIKNTGAVAILQLNHGGAKAYSKDKSELLSPSGVLAPNVTQEVTPRQMTLGEIAQVKADFIKATERAMEAGFD
GVEIHGAHGFLLNQFNSPLTNFRQDKYGGSRKNRARLSLEVASDLKEVVGNKLLLYRLGATDGYDKGLTMPDAIWIAKEL
VRNGVDIIDVSGGHGGYRGHTRSQGYFVPIAVEIKQNLTQPVMVAGGISSPQYANEVIEEEGLDFVGVGRALLSRPDWPY
MAKQELINRK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=333, Percent_Identity=26.4264264264264, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787939, Length=340, Percent_Identity=27.9411764705882, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI72001454, Length=254, Percent_Identity=31.1023622047244, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17540738, Length=258, Percent_Identity=31.3953488372093, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17559804, Length=297, Percent_Identity=29.6296296296296, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17565138, Length=265, Percent_Identity=31.3207547169811, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=253, Percent_Identity=30.8300395256917, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17564188, Length=297, Percent_Identity=27.6094276094276, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17566914, Length=334, Percent_Identity=29.6407185628743, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=355, Percent_Identity=27.0422535211268, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325086, Length=231, Percent_Identity=32.034632034632, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 36235; Mature: 36104

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFEPKKVKDFLFKNRIIMPPMVSEKATEQGQVTDKNVEYYLDRAKEGLAGVIVEPAF
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCE
ISENGRCSRHQLSAADDDKVEGLSRLASSIKNTGAVAILQLNHGGAKAYSKDKSELLSPS
ECCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCHHHHCCCC
GVLAPNVTQEVTPRQMTLGEIAQVKADFIKATERAMEAGFDGVEIHGAHGFLLNQFNSPL
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCHH
TNFRQDKYGGSRKNRARLSLEVASDLKEVVGNKLLLYRLGATDGYDKGLTMPDAIWIAKE
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
LVRNGVDIIDVSGGHGGYRGHTRSQGYFVPIAVEIKQNLTQPVMVAGGISSPQYANEVIE
HHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEEEHHHCCCCCEEEECCCCCHHHHHHHHH
EEGLDFVGVGRALLSRPDWPYMAKQELINRK
HCCCCEEEHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TALFEPKKVKDFLFKNRIIMPPMVSEKATEQGQVTDKNVEYYLDRAKEGLAGVIVEPAF
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCE
ISENGRCSRHQLSAADDDKVEGLSRLASSIKNTGAVAILQLNHGGAKAYSKDKSELLSPS
ECCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCHHHHCCCC
GVLAPNVTQEVTPRQMTLGEIAQVKADFIKATERAMEAGFDGVEIHGAHGFLLNQFNSPL
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCHH
TNFRQDKYGGSRKNRARLSLEVASDLKEVVGNKLLLYRLGATDGYDKGLTMPDAIWIAKE
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
LVRNGVDIIDVSGGHGGYRGHTRSQGYFVPIAVEIKQNLTQPVMVAGGISSPQYANEVIE
HHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEEEHHHCCCCCEEEECCCCCHHHHHHHHH
EEGLDFVGVGRALLSRPDWPYMAKQELINRK
HCCCCEEEHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA