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The map label for this gene is degU [H]

Identifier: 188586925

GI number: 188586925

Start: 2465397

End: 2466575

Strand: Reverse

Name: degU [H]

Synonym: Nther_2317

Alternate gene names: 188586925

Gene position: 2466575-2465397 (Counterclockwise)

Preceding gene: 188586926

Following gene: 188586924

Centisome position: 77.92

GC content: 38.59

Gene sequence:

>1179_bases
ATGAAACGTAAGATAGATATTTTAATAGCCGATGATATTTCAGAAACCAGAGAAAATATCAAGCGATTTTTAGGATTTGA
GCGGGATATTCAAATAGTGGGAGAAGCAGCCAATGGCGAACAGGCTATTAGCATGGCGGAAAAGATGAAACCGGACATAA
TCCTAATAGATATTAATATGCCTTTAGTTGACGGTATTAGCGCAATCGAAAGTTTGTCATTAAAAGCCCCTCAGGTAGCC
CCTATAGTTATATCTGTACAAGGTGAGGCAGAATACTTTAAAAAAGCCATGAGGGCTGGAGCGAGAGATTACCTGGTGAA
ACCATTTTCCGGAGATGAATTGATTTCTACAATTAAGGAAGTTGTTCAAAAAGAAGAGGAAGTCAGAGAAAAACAAATGA
ATGAAGCTCTACTTAGGTCAGGAATCAAGCACAAGCCCAGGATTTTTTCTGTATTTAGTGCAAAAGGTGGGACCGGGAAA
ACTACTTTAGCGGCAAATTTAGCCAGCTGCTTATCCAAATTTCATGATAAAAAGACTGTTATAGTTGATTTGGACCTGCA
GTTTGGCGATATTCCCATAATGTTCAATATCACCCCACAACAGACTATCACAGATCTGCTTTCCAATATTAATGAACTGG
ATAGTGAAACCCTGGAGAATGTCTTAATTCATCACGAGGAAACGGGTGTTAAGCTTTTGTGCCCACCTAAAAACCCTGAA
GAAGCAGAATATGTATCTGATGAACACGTGGAAGAAATCCTGAGAGTGTTGACGGAAACTTATGAATATATTTTAGTTGA
TACGCCACCAGCTTTTTCGGGGCATGTTTTATCGGCACTAGATCAGTCCCATAAGATATTTTTGGTTACTACTCTGGATT
TACCCTCAATAAAAAATGCAAAAAACTCAATTAATATAATGGACAACCTGGGCTATCCTGAAGACAAAGTTAACCTTGTA
GTCAATAAAGAGGATAAGTACTATCAGGTGGGGAAGCAAGACTTACAGGACGCACTGAATCGGGGTATATTTTATCGCAT
GCCTAATAAAGAAAAACCCATTGTAGAGGCTATTAACAGGGGCGTGCCCGTAATTTTAGAGCCTTCTGTCAATGGTGTAG
TAAGTGAATTCAGGAAGTTTTCCAATAAGGTTATTGAACATGAAAAAAGGGTTGAATAA

Upstream 100 bases:

>100_bases
TTAATCGTAATGAAGCTACTGAACTTACCCATGCTGAAGAAGAACATGTGATCAGGTTGCTATTACAGCCTATTACCGAG
AATTAAAGGGAGGGGTAGAA

Downstream 100 bases:

>100_bases
AACTTGGTGGGTCTCGGATCTGGGATAAGGGGGGTGACTTTATGAGCAACAAGCTAGAAAAATTAAGACAAAGACAAGCA
GCTTTACTGAAACAGGCTAG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKRKIDILIADDISETRENIKRFLGFERDIQIVGEAANGEQAISMAEKMKPDIILIDINMPLVDGISAIESLSLKAPQVA
PIVISVQGEAEYFKKAMRAGARDYLVKPFSGDELISTIKEVVQKEEEVREKQMNEALLRSGIKHKPRIFSVFSAKGGTGK
TTLAANLASCLSKFHDKKTVIVDLDLQFGDIPIMFNITPQQTITDLLSNINELDSETLENVLIHHEETGVKLLCPPKNPE
EAEYVSDEHVEEILRVLTETYEYILVDTPPAFSGHVLSALDQSHKIFLVTTLDLPSIKNAKNSINIMDNLGYPEDKVNLV
VNKEDKYYQVGKQDLQDALNRGIFYRMPNKEKPIVEAINRGVPVILEPSVNGVVSEFRKFSNKVIEHEKRVE

Sequences:

>Translated_392_residues
MKRKIDILIADDISETRENIKRFLGFERDIQIVGEAANGEQAISMAEKMKPDIILIDINMPLVDGISAIESLSLKAPQVA
PIVISVQGEAEYFKKAMRAGARDYLVKPFSGDELISTIKEVVQKEEEVREKQMNEALLRSGIKHKPRIFSVFSAKGGTGK
TTLAANLASCLSKFHDKKTVIVDLDLQFGDIPIMFNITPQQTITDLLSNINELDSETLENVLIHHEETGVKLLCPPKNPE
EAEYVSDEHVEEILRVLTETYEYILVDTPPAFSGHVLSALDQSHKIFLVTTLDLPSIKNAKNSINIMDNLGYPEDKVNLV
VNKEDKYYQVGKQDLQDALNRGIFYRMPNKEKPIVEAINRGVPVILEPSVNGVVSEFRKFSNKVIEHEKRVE
>Mature_392_residues
MKRKIDILIADDISETRENIKRFLGFERDIQIVGEAANGEQAISMAEKMKPDIILIDINMPLVDGISAIESLSLKAPQVA
PIVISVQGEAEYFKKAMRAGARDYLVKPFSGDELISTIKEVVQKEEEVREKQMNEALLRSGIKHKPRIFSVFSAKGGTGK
TTLAANLASCLSKFHDKKTVIVDLDLQFGDIPIMFNITPQQTITDLLSNINELDSETLENVLIHHEETGVKLLCPPKNPE
EAEYVSDEHVEEILRVLTETYEYILVDTPPAFSGHVLSALDQSHKIFLVTTLDLPSIKNAKNSINIMDNLGYPEDKVNLV
VNKEDKYYQVGKQDLQDALNRGIFYRMPNKEKPIVEAINRGVPVILEPSVNGVVSEFRKFSNKVIEHEKRVE

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG4963

COG function: function code U; Flp pilus assembly protein, ATPase CpaE

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=128, Percent_Identity=35.9375, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788222, Length=117, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=139, Percent_Identity=32.3741007194245, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787473, Length=119, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790102, Length=117, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787423, Length=162, Percent_Identity=26.5432098765432, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 44039; Mature: 44039

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKIDILIADDISETRENIKRFLGFERDIQIVGEAANGEQAISMAEKMKPDIILIDINM
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCC
PLVDGISAIESLSLKAPQVAPIVISVQGEAEYFKKAMRAGARDYLVKPFSGDELISTIKE
CHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHCCCHHCEECCCCCHHHHHHHHH
VVQKEEEVREKQMNEALLRSGIKHKPRIFSVFSAKGGTGKTTLAANLASCLSKFHDKKTV
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEE
IVDLDLQFGDIPIMFNITPQQTITDLLSNINELDSETLENVLIHHEETGVKLLCPPKNPE
EEEEEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCC
EAEYVSDEHVEEILRVLTETYEYILVDTPPAFSGHVLSALDQSHKIFLVTTLDLPSIKNA
HHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCC
KNSINIMDNLGYPEDKVNLVVNKEDKYYQVGKQDLQDALNRGIFYRMPNKEKPIVEAINR
CCCEEEHCCCCCCCCCEEEEECCCCCHHHHCHHHHHHHHHCCEEEECCCCCCHHHHHHHC
GVPVILEPSVNGVVSEFRKFSNKVIEHEKRVE
CCCEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRKIDILIADDISETRENIKRFLGFERDIQIVGEAANGEQAISMAEKMKPDIILIDINM
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCC
PLVDGISAIESLSLKAPQVAPIVISVQGEAEYFKKAMRAGARDYLVKPFSGDELISTIKE
CHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHCCCHHCEECCCCCHHHHHHHHH
VVQKEEEVREKQMNEALLRSGIKHKPRIFSVFSAKGGTGKTTLAANLASCLSKFHDKKTV
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEE
IVDLDLQFGDIPIMFNITPQQTITDLLSNINELDSETLENVLIHHEETGVKLLCPPKNPE
EEEEEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCC
EAEYVSDEHVEEILRVLTETYEYILVDTPPAFSGHVLSALDQSHKIFLVTTLDLPSIKNA
HHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCC
KNSINIMDNLGYPEDKVNLVVNKEDKYYQVGKQDLQDALNRGIFYRMPNKEKPIVEAINR
CCCEEEHCCCCCCCCCEEEEECCCCCHHHHCHHHHHHHHHCCEEEECCCCCCHHHHHHHC
GVPVILEPSVNGVVSEFRKFSNKVIEHEKRVE
CCCEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]