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The map label for this gene is yeeO [C]

Identifier: 188586900

GI number: 188586900

Start: 2434869

End: 2436251

Strand: Reverse

Name: yeeO [C]

Synonym: Nther_2291

Alternate gene names: 188586900

Gene position: 2436251-2434869 (Counterclockwise)

Preceding gene: 188586901

Following gene: 188586893

Centisome position: 76.96

GC content: 43.31

Gene sequence:

>1383_bases
ATGGCCGGGGGAGCTCAATTAGCCCAGCAGAATAAACGCGACCTGACTACAGGTAGTATACCGAAAAAACTAATAAGATT
GGCACTTCCCATTATGGGGGGTATGTTTCTCCAAACGATATTCAATATAGTAGACACTTTTTTTGTAAGTCAGCTGGGTC
ATAATGCTATTGCGGCAGTTAGCATGAATATGCCCATCTTATTTATTCTAATAGCCATGGGTAATGCTGTGGCCGTTGGT
ACCAGTTCTTATATTGCTCGCAGTATTGGAGCAGGCGAAGATGAAAAAGCACGGAAAACAGCATCCCAAGCCATAACCCT
GGCAGTAATCCTAGGGATAGTTGCCACAATTATAGGTGTCAGTTTTGCCCCATATATAATTTCATTTATGGGAGCCGAAG
GAGAATTGTATTCTTTGGCAGTGGAATATACCAGCATCATATTCTGGGGTAATTTGATATTCTTTTTATTTTTGGCTTTA
GATGGAGTTCTCCGGGGAGAAGGAGATATGAAAACCTCAATGATGAAGCAAGTGGTTGGGGTTGGTTTCAATATTCTTTT
GGATCCGATTTTTATATTTGGACTGGGGCCTGTGCCTGCCATGGGAGTTGCAGGAGCGGCCTTAGCCATAGTACTTAGTA
GGTTTTTAGGATTATTATTTCTGGTATGGCACTTTTCTACGGGAAGGTCTACAATTAAATTTAATATGACCAAGTTTGTC
TTTGAATCGGAAATTATCAAACAAATCATGGCTGTCGGATTGCCTACATCAGCCTCTCAGGCCATGATGTCTTTGACTCT
GTTTGTATACAATCGTCTAGCTTCTGGTTTCGGTGACGAAGCCGTGGCTGCCCTGGGCCTTGGCTTTAGGATAGATTCCC
TGGCAATACTGCCTGGAATTGCTATTGGAATTAGTATGGTTACCATGGTGGGACAAAATTATGGAGCTGGTGAACTCGAA
CGAGTACGTAGGTCTTATTGGACTGCCCAGGCCATGGCTGCTGGTTTTATGGCCTCTGTAGGTGTATTTTTATTTGCGTT
TCCGGAATTTTTTATTGGCATATTTTCCCAGGAACAAGACGTTATGAGTCACGGAGTCAGTTACCTTAGGATATTACCTA
TCTTTTATCCCTTCCTGGGTAGTGGCCTGATTTCAGCTCATTCATTCCAAGGACTGGGCAAAGCCATTCCGGCTCTGATT
ATCAGTCTAATCAGGGTTGGTCTGGTGGGGATCCCTCTGGCTCTATTTTTGACTTCTCAAACTGGTTTGGGAGCGTCCGG
AATCTGGCTAGCCCTTGGATTAAGTGATTTCACCTTTTTCGGTGTGGGAATGCTTTGGTTCAAGAGTACCTTTAAGAGGA
TGACTAGATTTGTCCATTCATAG

Upstream 100 bases:

>100_bases
TCCTTGGGCTCTTTTTTATTTTATTGATAAGTGATAATATGACTGCTAGGGATTAAGTGATAGCTATTTTATTATAAATA
TTAAGTGAGAGGTGAGGGGA

Downstream 100 bases:

>100_bases
TAAAAAGTGAATTATTACTTTTTTCCCAAGTAAAAATAGCTATTTTCATCGGATTGGGCCACCTGTGTTGTCAGGCGGTT
TTTTTCTGCCATTTTTTGAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MAGGAQLAQQNKRDLTTGSIPKKLIRLALPIMGGMFLQTIFNIVDTFFVSQLGHNAIAAVSMNMPILFILIAMGNAVAVG
TSSYIARSIGAGEDEKARKTASQAITLAVILGIVATIIGVSFAPYIISFMGAEGELYSLAVEYTSIIFWGNLIFFLFLAL
DGVLRGEGDMKTSMMKQVVGVGFNILLDPIFIFGLGPVPAMGVAGAALAIVLSRFLGLLFLVWHFSTGRSTIKFNMTKFV
FESEIIKQIMAVGLPTSASQAMMSLTLFVYNRLASGFGDEAVAALGLGFRIDSLAILPGIAIGISMVTMVGQNYGAGELE
RVRRSYWTAQAMAAGFMASVGVFLFAFPEFFIGIFSQEQDVMSHGVSYLRILPIFYPFLGSGLISAHSFQGLGKAIPALI
ISLIRVGLVGIPLALFLTSQTGLGASGIWLALGLSDFTFFGVGMLWFKSTFKRMTRFVHS

Sequences:

>Translated_460_residues
MAGGAQLAQQNKRDLTTGSIPKKLIRLALPIMGGMFLQTIFNIVDTFFVSQLGHNAIAAVSMNMPILFILIAMGNAVAVG
TSSYIARSIGAGEDEKARKTASQAITLAVILGIVATIIGVSFAPYIISFMGAEGELYSLAVEYTSIIFWGNLIFFLFLAL
DGVLRGEGDMKTSMMKQVVGVGFNILLDPIFIFGLGPVPAMGVAGAALAIVLSRFLGLLFLVWHFSTGRSTIKFNMTKFV
FESEIIKQIMAVGLPTSASQAMMSLTLFVYNRLASGFGDEAVAALGLGFRIDSLAILPGIAIGISMVTMVGQNYGAGELE
RVRRSYWTAQAMAAGFMASVGVFLFAFPEFFIGIFSQEQDVMSHGVSYLRILPIFYPFLGSGLISAHSFQGLGKAIPALI
ISLIRVGLVGIPLALFLTSQTGLGASGIWLALGLSDFTFFGVGMLWFKSTFKRMTRFVHS
>Mature_459_residues
AGGAQLAQQNKRDLTTGSIPKKLIRLALPIMGGMFLQTIFNIVDTFFVSQLGHNAIAAVSMNMPILFILIAMGNAVAVGT
SSYIARSIGAGEDEKARKTASQAITLAVILGIVATIIGVSFAPYIISFMGAEGELYSLAVEYTSIIFWGNLIFFLFLALD
GVLRGEGDMKTSMMKQVVGVGFNILLDPIFIFGLGPVPAMGVAGAALAIVLSRFLGLLFLVWHFSTGRSTIKFNMTKFVF
ESEIIKQIMAVGLPTSASQAMMSLTLFVYNRLASGFGDEAVAALGLGFRIDSLAILPGIAIGISMVTMVGQNYGAGELER
VRRSYWTAQAMAAGFMASVGVFLFAFPEFFIGIFSQEQDVMSHGVSYLRILPIFYPFLGSGLISAHSFQGLGKAIPALII
SLIRVGLVGIPLALFLTSQTGLGASGIWLALGLSDFTFFGVGMLWFKSTFKRMTRFVHS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=447, Percent_Identity=22.1476510067114, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994890, Length=303, Percent_Identity=25.0825082508251, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49294; Mature: 49163

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGAQLAQQNKRDLTTGSIPKKLIRLALPIMGGMFLQTIFNIVDTFFVSQLGHNAIAAV
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SMNMPILFILIAMGNAVAVGTSSYIARSIGAGEDEKARKTASQAITLAVILGIVATIIGV
ECCCHHHHHHHHHCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAPYIISFMGAEGELYSLAVEYTSIIFWGNLIFFLFLALDGVLRGEGDMKTSMMKQVVG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VGFNILLDPIFIFGLGPVPAMGVAGAALAIVLSRFLGLLFLVWHFSTGRSTIKFNMTKFV
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
FESEIIKQIMAVGLPTSASQAMMSLTLFVYNRLASGFGDEAVAALGLGFRIDSLAILPGI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
AIGISMVTMVGQNYGAGELERVRRSYWTAQAMAAGFMASVGVFLFAFPEFFIGIFSQEQD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VMSHGVSYLRILPIFYPFLGSGLISAHSFQGLGKAIPALIISLIRVGLVGIPLALFLTSQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGLGASGIWLALGLSDFTFFGVGMLWFKSTFKRMTRFVHS
CCCCCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGGAQLAQQNKRDLTTGSIPKKLIRLALPIMGGMFLQTIFNIVDTFFVSQLGHNAIAAV
CCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SMNMPILFILIAMGNAVAVGTSSYIARSIGAGEDEKARKTASQAITLAVILGIVATIIGV
ECCCHHHHHHHHHCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAPYIISFMGAEGELYSLAVEYTSIIFWGNLIFFLFLALDGVLRGEGDMKTSMMKQVVG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VGFNILLDPIFIFGLGPVPAMGVAGAALAIVLSRFLGLLFLVWHFSTGRSTIKFNMTKFV
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
FESEIIKQIMAVGLPTSASQAMMSLTLFVYNRLASGFGDEAVAALGLGFRIDSLAILPGI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
AIGISMVTMVGQNYGAGELERVRRSYWTAQAMAAGFMASVGVFLFAFPEFFIGIFSQEQD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VMSHGVSYLRILPIFYPFLGSGLISAHSFQGLGKAIPALIISLIRVGLVGIPLALFLTSQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGLGASGIWLALGLSDFTFFGVGMLWFKSTFKRMTRFVHS
CCCCCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]