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The map label for this gene is ubiE [C]

Identifier: 188586899

GI number: 188586899

Start: 2434174

End: 2434854

Strand: Direct

Name: ubiE [C]

Synonym: Nther_2290

Alternate gene names: 188586899

Gene position: 2434174-2434854 (Clockwise)

Preceding gene: 188586898

Following gene: 188586907

Centisome position: 76.9

GC content: 36.71

Gene sequence:

>681_bases
GTGGATATTAATAAAAAGTCAAACAATAATGAATCTACAAATAATGAGAATGATGTAAATACGGATGAAAAGCAAGAAAA
TACGAATGAAAGACAAGAAACAAAAGCCTTTTTTGATACAGCATCCCAGTACTGGGATGACCGCATTGTTCACAATGAAG
ATATCATCCGGGATTCCCTGAGTTATATTGATTTCGAGTCGAAGAATAGAGTACTTGATGTAGGAACCGGTACCGGCATC
ATGCTAAAGTTTTTACTCCCAAATCTATCAGAGACAGCTTCAATTCTAGCTGTTGACTTATCACCACAGATGATTGCCAA
GGCAAAAGGAAAATATCGTGACCAACGCATTAAGTTTCAAGAACTAGATGTAGAAACAGAACCTTTTCAAAATGAACAGT
TTGATTTGATAATCCTATACTCTGTATTCCCTCACTTGAACGATAAAAGCCGAGTTTTAAGACATTTAAGCAAATCTCTG
ATAACCGGTGGAGAACTTTGCATTCTCCATTCCAAGTCCAGAGCAGAAATTAATGACATGCATAAAAGTTTAGGTAATCC
TGTTTCAAATCACCTGCTCCCACCTATTAGTGAACTTCAAAAAATGGCAGAAAAAAACCGCCTGACAACACAGGTGGCCC
AATCCGATGAAAATAGCTATTTTTACTTGGGAAAAAAGTAA

Upstream 100 bases:

>100_bases
GTTGCAGTTATTCTTAATACCTTTAATAATTAACCGCCTAGAAAGTAAGTAAATTTGCCGCCAGAAAAGTAAGTCTAATG
CTTAAACAGGAGGGATACAA

Downstream 100 bases:

>100_bases
TAATTCACTTTTTACTATGAATGGACAAATCTAGTCATCCTCTTAAAGGTACTCTTGAACCAAAGCATTCCCACACCGAA
AAAGGTGAAATCACTTAATC

Product: Methyltransferase type 11

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Menaquinone Biosynthesis Methyltransferase UbiE; Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Family Protein; Methyltransferase Domain Protein; UbiE/COQ5 Family Methlytransferase; Methyltransferase With A HTH Motif; Methyltransferase UbiE/COQ5 Family; Methlytransferase; UbiE/COQ5 Methyltransferase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDINKKSNNNESTNNENDVNTDEKQENTNERQETKAFFDTASQYWDDRIVHNEDIIRDSLSYIDFESKNRVLDVGTGTGI
MLKFLLPNLSETASILAVDLSPQMIAKAKGKYRDQRIKFQELDVETEPFQNEQFDLIILYSVFPHLNDKSRVLRHLSKSL
ITGGELCILHSKSRAEINDMHKSLGNPVSNHLLPPISELQKMAEKNRLTTQVAQSDENSYFYLGKK

Sequences:

>Translated_226_residues
MDINKKSNNNESTNNENDVNTDEKQENTNERQETKAFFDTASQYWDDRIVHNEDIIRDSLSYIDFESKNRVLDVGTGTGI
MLKFLLPNLSETASILAVDLSPQMIAKAKGKYRDQRIKFQELDVETEPFQNEQFDLIILYSVFPHLNDKSRVLRHLSKSL
ITGGELCILHSKSRAEINDMHKSLGNPVSNHLLPPISELQKMAEKNRLTTQVAQSDENSYFYLGKK
>Mature_226_residues
MDINKKSNNNESTNNENDVNTDEKQENTNERQETKAFFDTASQYWDDRIVHNEDIIRDSLSYIDFESKNRVLDVGTGTGI
MLKFLLPNLSETASILAVDLSPQMIAKAKGKYRDQRIKFQELDVETEPFQNEQFDLIILYSVFPHLNDKSRVLRHLSKSL
ITGGELCILHSKSRAEINDMHKSLGNPVSNHLLPPISELQKMAEKNRLTTQVAQSDENSYFYLGKK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 25953; Mature: 25953

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINKKSNNNESTNNENDVNTDEKQENTNERQETKAFFDTASQYWDDRIVHNEDIIRDSL
CCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SYIDFESKNRVLDVGTGTGIMLKFLLPNLSETASILAVDLSPQMIAKAKGKYRDQRIKFQ
HHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCHHHHHCCHH
ELDVETEPFQNEQFDLIILYSVFPHLNDKSRVLRHLSKSLITGGELCILHSKSRAEINDM
HCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
HKSLGNPVSNHLLPPISELQKMAEKNRLTTQVAQSDENSYFYLGKK
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MDINKKSNNNESTNNENDVNTDEKQENTNERQETKAFFDTASQYWDDRIVHNEDIIRDSL
CCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SYIDFESKNRVLDVGTGTGIMLKFLLPNLSETASILAVDLSPQMIAKAKGKYRDQRIKFQ
HHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCHHHHHCCHH
ELDVETEPFQNEQFDLIILYSVFPHLNDKSRVLRHLSKSLITGGELCILHSKSRAEINDM
HCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
HKSLGNPVSNHLLPPISELQKMAEKNRLTTQVAQSDENSYFYLGKK
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA