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The map label for this gene is stc [H]

Identifier: 188586771

GI number: 188586771

Start: 2288892

End: 2290568

Strand: Reverse

Name: stc [H]

Synonym: Nther_2162

Alternate gene names: 188586771

Gene position: 2290568-2288892 (Counterclockwise)

Preceding gene: 188586773

Following gene: 188586770

Centisome position: 72.36

GC content: 36.61

Gene sequence:

>1677_bases
TTGGGAAGTTATCAAAAGAATTTAAATGACAACCTAAATGATAGGGATAGCAACACTTTTGAAAGTTTAGCCAAGAGCTT
ACCCCTTTTGGCTAAAGTGATTGGTGGTTATGCCACTATTACTGACAAAAAAGGGGTCAGGCTGAAGGTTATTGATTCCA
ATGGGAAGCAGCTAGAGCACCTGGAAGACCTACAGTATGAGTTAGCCAGGGAAGCTGCTAAAAAAGGGGAAGCAGTCTAC
GGTAATAGCCAGCTAAAACATAATGCTGAAGCTTGGTGTCTACCAGTTGGCGATTATGTGCTCTGCTGCAGTAAGGCGGA
AGTGGCAGAACGAAACAGGAATCTTGAAGAAGCTTTATTGGCATCTTTACCTTATATTGCAAAAGTAGCAGGGGGACAAG
CCGTCCTCTTTGATGATGAAGGAAAAAGACTTAATGCAGTTAATTCCAAGGGAGATGTCAACAATCAATTACTTGGCAAA
GTTAGTGAAGCCGCCAAGGAATGTATGAAAGCTCAAAAGCCTGTACTGGGGAAATCTACTTTTATCAGTGGTGCCAGTGC
TGTTAGGATTCCCATTACTAAGGAAATTGGATTTGGATTTAATAATGAAGATACAGCTCTTAAAAATCAAAAGCTTTTAG
AAGAAGTTAAAAAATATCAGACTGCTAAATACAATTTTACTGACATAATTGGTGAAAGTCAGCAGATGAGAAAAGCTAAA
GAATTGGGAGAAGCTGCTGCCAGTTCCGATTCAAGTGTACTAATTTGCGGTGAGACAGGTACTGGTAAAGAATTATTTGC
CCAATCAATTCACAATGCAAGCTATAGATGCAGTAAACCTTTTATAGCTATTAATTGTGCTGCACTTCCGCCATCATTGA
TCGAGAGTAATTTATTCGGTTATGTGGAAGGAGCTTTTACTGGCGCTAAAAAAGGTGGAGCTACTGGAGTTTTTGAAAAA
GCTAATAATGGAACTTTATTTTTGGACGAAATTAGCGAAATGGACTTGGATCTACAGTCAAAATTATTGCGGGTATTACA
AGAAAAAGAAGTCACTAGAATTGGTGGTCGCAAGGTAATTCCCTTAAACCTACGAATAATTGCAGCTACTAACAGGAACT
TGGAAGACATGATTCAAAAGGGACAGTTTAGACGAGATTTATTTTTTAGATTAAATGTAATAGAAGTTAAATTACCACCA
TTAAGAGATATGAAAGAAGATATCCCCTTGCTTGTTAATGAAACAATTATTAAAATGAATTCGATTTTCGGTAAGGCCAT
TAAGGGTGTCGACAAAGAAGCGCTGGAAATGCTGATAAATTATGATTGGCCTGGAAATGTACGAGAATTATATAACTGTA
TAGAAAGAGCTTTTAATCTGATTGGTGATGATAATTACATTAGAAAAAAGCATTTAAACTTTAAATTTAATAATGGCAAT
GGTATTACAGCCCAGAATTACATGGAGGAAATAGAAGATACCGAAGGTAATCCAATTAATCTAGATAATGATACAGGACA
AAGAAGTCTCGATGATATAGTTGCTAATTACGAAAAACAAGTAATTGAGGCAGTGTTGAAAGAAGTTAAAGGAATTAGGG
CCAAAGCTGCCAAAAGATTAAATATAAGTCCGGCTACATTGTGGAGAAAAATGAAAAAGTTAAATATTGAGGGTTAA

Upstream 100 bases:

>100_bases
TTATAATGGATTTAATCAATTAAATTATAACTAATAAAATAATAAACTAATGATTTCAATATTCTATCACAACTAAGCTC
ATTAGTCAGGGGGATTAGCA

Downstream 100 bases:

>100_bases
TATAAATAAATTGGATCTTAACAAATGGAACTTATATGAAAGTATATCATACAAGAAATCTATTCACAGTTGACAGATTG
AGAAGCATTTCAATATTGAA

Product: putative sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MGSYQKNLNDNLNDRDSNTFESLAKSLPLLAKVIGGYATITDKKGVRLKVIDSNGKQLEHLEDLQYELAREAAKKGEAVY
GNSQLKHNAEAWCLPVGDYVLCCSKAEVAERNRNLEEALLASLPYIAKVAGGQAVLFDDEGKRLNAVNSKGDVNNQLLGK
VSEAAKECMKAQKPVLGKSTFISGASAVRIPITKEIGFGFNNEDTALKNQKLLEEVKKYQTAKYNFTDIIGESQQMRKAK
ELGEAAASSDSSVLICGETGTGKELFAQSIHNASYRCSKPFIAINCAALPPSLIESNLFGYVEGAFTGAKKGGATGVFEK
ANNGTLFLDEISEMDLDLQSKLLRVLQEKEVTRIGGRKVIPLNLRIIAATNRNLEDMIQKGQFRRDLFFRLNVIEVKLPP
LRDMKEDIPLLVNETIIKMNSIFGKAIKGVDKEALEMLINYDWPGNVRELYNCIERAFNLIGDDNYIRKKHLNFKFNNGN
GITAQNYMEEIEDTEGNPINLDNDTGQRSLDDIVANYEKQVIEAVLKEVKGIRAKAAKRLNISPATLWRKMKKLNIEG

Sequences:

>Translated_558_residues
MGSYQKNLNDNLNDRDSNTFESLAKSLPLLAKVIGGYATITDKKGVRLKVIDSNGKQLEHLEDLQYELAREAAKKGEAVY
GNSQLKHNAEAWCLPVGDYVLCCSKAEVAERNRNLEEALLASLPYIAKVAGGQAVLFDDEGKRLNAVNSKGDVNNQLLGK
VSEAAKECMKAQKPVLGKSTFISGASAVRIPITKEIGFGFNNEDTALKNQKLLEEVKKYQTAKYNFTDIIGESQQMRKAK
ELGEAAASSDSSVLICGETGTGKELFAQSIHNASYRCSKPFIAINCAALPPSLIESNLFGYVEGAFTGAKKGGATGVFEK
ANNGTLFLDEISEMDLDLQSKLLRVLQEKEVTRIGGRKVIPLNLRIIAATNRNLEDMIQKGQFRRDLFFRLNVIEVKLPP
LRDMKEDIPLLVNETIIKMNSIFGKAIKGVDKEALEMLINYDWPGNVRELYNCIERAFNLIGDDNYIRKKHLNFKFNNGN
GITAQNYMEEIEDTEGNPINLDNDTGQRSLDDIVANYEKQVIEAVLKEVKGIRAKAAKRLNISPATLWRKMKKLNIEG
>Mature_557_residues
GSYQKNLNDNLNDRDSNTFESLAKSLPLLAKVIGGYATITDKKGVRLKVIDSNGKQLEHLEDLQYELAREAAKKGEAVYG
NSQLKHNAEAWCLPVGDYVLCCSKAEVAERNRNLEEALLASLPYIAKVAGGQAVLFDDEGKRLNAVNSKGDVNNQLLGKV
SEAAKECMKAQKPVLGKSTFISGASAVRIPITKEIGFGFNNEDTALKNQKLLEEVKKYQTAKYNFTDIIGESQQMRKAKE
LGEAAASSDSSVLICGETGTGKELFAQSIHNASYRCSKPFIAINCAALPPSLIESNLFGYVEGAFTGAKKGGATGVFEKA
NNGTLFLDEISEMDLDLQSKLLRVLQEKEVTRIGGRKVIPLNLRIIAATNRNLEDMIQKGQFRRDLFFRLNVIEVKLPPL
RDMKEDIPLLVNETIIKMNSIFGKAIKGVDKEALEMLINYDWPGNVRELYNCIERAFNLIGDDNYIRKKHLNFKFNNGNG
ITAQNYMEEIEDTEGNPINLDNDTGQRSLDDIVANYEKQVIEAVLKEVKGIRAKAAKRLNISPATLWRKMKKLNIEG

Specific function: Required For Induction Of Expression Of The Hydrogenase- 4 Structural Genes. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=337, Percent_Identity=46.5875370919881, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1789233, Length=329, Percent_Identity=44.3768996960486, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1788550, Length=356, Percent_Identity=42.6966292134831, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1786524, Length=247, Percent_Identity=48.1781376518219, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789087, Length=351, Percent_Identity=42.4501424501425, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790437, Length=325, Percent_Identity=40.3076923076923, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1788905, Length=232, Percent_Identity=49.5689655172414, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1790299, Length=336, Percent_Identity=39.8809523809524, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87082152, Length=336, Percent_Identity=38.6904761904762, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787583, Length=331, Percent_Identity=33.8368580060423, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081872, Length=240, Percent_Identity=43.75, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87081858, Length=495, Percent_Identity=28.2828282828283, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789828, Length=229, Percent_Identity=33.6244541484716, Blast_Score=132, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 61911; Mature: 61779

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSYQKNLNDNLNDRDSNTFESLAKSLPLLAKVIGGYATITDKKGVRLKVIDSNGKQLEH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHH
LEDLQYELAREAAKKGEAVYGNSQLKHNAEAWCLPVGDYVLCCSKAEVAERNRNLEEALL
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCEEEECCCHHHHHHCCCHHHHHH
ASLPYIAKVAGGQAVLFDDEGKRLNAVNSKGDVNNQLLGKVSEAAKECMKAQKPVLGKST
HHCCHHHHHCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHH
FISGASAVRIPITKEIGFGFNNEDTALKNQKLLEEVKKYQTAKYNFTDIIGESQQMRKAK
EECCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHH
ELGEAAASSDSSVLICGETGTGKELFAQSIHNASYRCSKPFIAINCAALPPSLIESNLFG
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCHH
YVEGAFTGAKKGGATGVFEKANNGTLFLDEISEMDLDLQSKLLRVLQEKEVTRIGGRKVI
EEHHHHCCCCCCCCCCEEEECCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHCCCCEEE
PLNLRIIAATNRNLEDMIQKGQFRRDLFFRLNVIEVKLPPLRDMKEDIPLLVNETIIKMN
EEEEEEEEECCCCHHHHHHCCCHHHHHEEEEEEEEEECCCCCCHHHCCCCHHHHHHHHHH
SIFGKAIKGVDKEALEMLINYDWPGNVRELYNCIERAFNLIGDDNYIRKKHLNFKFNNGN
HHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHEECCEEEECCC
GITAQNYMEEIEDTEGNPINLDNDTGQRSLDDIVANYEKQVIEAVLKEVKGIRAKAAKRL
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NISPATLWRKMKKLNIEG
CCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSYQKNLNDNLNDRDSNTFESLAKSLPLLAKVIGGYATITDKKGVRLKVIDSNGKQLEH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHH
LEDLQYELAREAAKKGEAVYGNSQLKHNAEAWCLPVGDYVLCCSKAEVAERNRNLEEALL
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCEEEECCCHHHHHHCCCHHHHHH
ASLPYIAKVAGGQAVLFDDEGKRLNAVNSKGDVNNQLLGKVSEAAKECMKAQKPVLGKST
HHCCHHHHHCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHH
FISGASAVRIPITKEIGFGFNNEDTALKNQKLLEEVKKYQTAKYNFTDIIGESQQMRKAK
EECCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHH
ELGEAAASSDSSVLICGETGTGKELFAQSIHNASYRCSKPFIAINCAALPPSLIESNLFG
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCHH
YVEGAFTGAKKGGATGVFEKANNGTLFLDEISEMDLDLQSKLLRVLQEKEVTRIGGRKVI
EEHHHHCCCCCCCCCCEEEECCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHCCCCEEE
PLNLRIIAATNRNLEDMIQKGQFRRDLFFRLNVIEVKLPPLRDMKEDIPLLVNETIIKMN
EEEEEEEEECCCCHHHHHHCCCHHHHHEEEEEEEEEECCCCCCHHHCCCCHHHHHHHHHH
SIFGKAIKGVDKEALEMLINYDWPGNVRELYNCIERAFNLIGDDNYIRKKHLNFKFNNGN
HHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHEECCEEEECCC
GITAQNYMEEIEDTEGNPINLDNDTGQRSLDDIVANYEKQVIEAVLKEVKGIRAKAAKRL
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NISPATLWRKMKKLNIEG
CCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA