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The map label for this gene is Ena [H]

Identifier: 188586753

GI number: 188586753

Start: 2267994

End: 2269157

Strand: Reverse

Name: Ena [H]

Synonym: Nther_2144

Alternate gene names: 188586753

Gene position: 2269157-2267994 (Counterclockwise)

Preceding gene: 188586754

Following gene: 188586751

Centisome position: 71.68

GC content: 39.18

Gene sequence:

>1164_bases
ATGTCAACTTTAGCTATCAAAAACATTGGCAAGTTAATTACAGGTGATCTTAATAATCCTGTGTCGGAACATGATACAAT
TATTGTAGTTAACGGAAAGATAAAAGAAATAGGTGGAACAGAGTTATTGAATAACTACGACTTGGATAAAGTTGTTGATG
CCAAGGGTACTACAGTAGCTCCTGGTTTGATCGATTCTCATGCTCATCCTGTTTTGGGAGATTTTACTCCTAGGCAAAAA
ACCATGGGTTTTATTGAAAGTTCACTTCACGGCGGTGTTTCAACAATGATTTCCGCAGGTGAACCACATACTCCAGGTAG
GCCTAAAGGGGACAAAGAAGGTGCTAAATCCTTGGCTAAGTTAGTTCATAAAAGCTTTAACAATTTAAGGCCCGGTGGTG
TAAAAGTTCACGGTGGAGCTTTAATTTTAGAAAAAGGATTAACTGAAGAAGATTTTAAAGAAGTGACTCGTGAAGGCGTT
TGGCTAGTAGGAGAAGTAGGTCTTGGCACAGTAAAGGATCCAGAAGAAGCTGCACCCATGATTGAAATGGCTAAAAACTA
CGGTATGAAGGTGATGATGCATACTGGCGGGACTTCTATTCCCGGTAGTAGTAATGTAGGGTATGAAGATGTCATCAATG
CAAAACCTACGGTGGTATCTCATTTAAATGGCGGGCCGACTTCTATTCCCTTTGATGACGTAAAAAAACTTATCGATAAT
TCCGACATAACTTTAGAACTTGTTCATAATGGCAATCCCAAAATAATGAAGCAAGCAGCAGAGTATGCCATGGAAAAGGA
TTGTCTTGATAGATTTATAATTGGTAATGATGCTCCTTCAGGAACGGGAGTAATAGTTCTCAGTATAATAAGAGTGATTT
CATTTTTATCATCTGTTGCTGGTATTCCTCCAGAAAAGGCCATTTGCATGGCTACAGGAAATACATCCAAAGTTTATGAT
TTAAATGTTGGTTTAATTGAAAAAGGCAGAGAGGCAGACTTTGTAATTATGGATGCTCCTATGGGATCGGTGGGTGAAGA
TAGTTTGACTGCATTCCAAGAAGGAGATCTACCAGGTGTATCAATGGTGATAGTTGATGGTGAAGTGATGTTTACCAAGA
GTAGAAACACTCCACCAGCCGTTAGAATGGCTGAAGTTCAATAG

Upstream 100 bases:

>100_bases
ACCCGCTTTTTAAGCATACAGCTTTTATAATGACTCTTAGAAGTTTCTGTTGATCAGGTTTTAAAACAGTGATAGTAAAA
CAGTAAGAGGAGGTATATAC

Downstream 100 bases:

>100_bases
TCAGATAAAAAAAGGGAGCCTTCTTGGCTCCCTTTGTACTTTACATCAAAGTTCTATATAGGTCTATTCAGGTGCTAAAA
AGGACTATTCAGGAAAATTA

Product: amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSTLAIKNIGKLITGDLNNPVSEHDTIIVVNGKIKEIGGTELLNNYDLDKVVDAKGTTVAPGLIDSHAHPVLGDFTPRQK
TMGFIESSLHGGVSTMISAGEPHTPGRPKGDKEGAKSLAKLVHKSFNNLRPGGVKVHGGALILEKGLTEEDFKEVTREGV
WLVGEVGLGTVKDPEEAAPMIEMAKNYGMKVMMHTGGTSIPGSSNVGYEDVINAKPTVVSHLNGGPTSIPFDDVKKLIDN
SDITLELVHNGNPKIMKQAAEYAMEKDCLDRFIIGNDAPSGTGVIVLSIIRVISFLSSVAGIPPEKAICMATGNTSKVYD
LNVGLIEKGREADFVIMDAPMGSVGEDSLTAFQEGDLPGVSMVIVDGEVMFTKSRNTPPAVRMAEVQ

Sequences:

>Translated_387_residues
MSTLAIKNIGKLITGDLNNPVSEHDTIIVVNGKIKEIGGTELLNNYDLDKVVDAKGTTVAPGLIDSHAHPVLGDFTPRQK
TMGFIESSLHGGVSTMISAGEPHTPGRPKGDKEGAKSLAKLVHKSFNNLRPGGVKVHGGALILEKGLTEEDFKEVTREGV
WLVGEVGLGTVKDPEEAAPMIEMAKNYGMKVMMHTGGTSIPGSSNVGYEDVINAKPTVVSHLNGGPTSIPFDDVKKLIDN
SDITLELVHNGNPKIMKQAAEYAMEKDCLDRFIIGNDAPSGTGVIVLSIIRVISFLSSVAGIPPEKAICMATGNTSKVYD
LNVGLIEKGREADFVIMDAPMGSVGEDSLTAFQEGDLPGVSMVIVDGEVMFTKSRNTPPAVRMAEVQ
>Mature_386_residues
STLAIKNIGKLITGDLNNPVSEHDTIIVVNGKIKEIGGTELLNNYDLDKVVDAKGTTVAPGLIDSHAHPVLGDFTPRQKT
MGFIESSLHGGVSTMISAGEPHTPGRPKGDKEGAKSLAKLVHKSFNNLRPGGVKVHGGALILEKGLTEEDFKEVTREGVW
LVGEVGLGTVKDPEEAAPMIEMAKNYGMKVMMHTGGTSIPGSSNVGYEDVINAKPTVVSHLNGGPTSIPFDDVKKLIDNS
DITLELVHNGNPKIMKQAAEYAMEKDCLDRFIIGNDAPSGTGVIVLSIIRVISFLSSVAGIPPEKAICMATGNTSKVYDL
NVGLIEKGREADFVIMDAPMGSVGEDSLTAFQEGDLPGVSMVIVDGEVMFTKSRNTPPAVRMAEVQ

Specific function: Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.18 [H]

Molecular weight: Translated: 41038; Mature: 40906

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLAIKNIGKLITGDLNNPVSEHDTIIVVNGKIKEIGGTELLNNYDLDKVVDAKGTTVA
CCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCEEECCCHHHHCCCCHHHHCCCCCCEEC
PGLIDSHAHPVLGDFTPRQKTMGFIESSLHGGVSTMISAGEPHTPGRPKGDKEGAKSLAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHH
LVHKSFNNLRPGGVKVHGGALILEKGLTEEDFKEVTREGVWLVGEVGLGTVKDPEEAAPM
HHHHHHHCCCCCCEEEECCEEEEECCCCHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
IEMAKNYGMKVMMHTGGTSIPGSSNVGYEDVINAKPTVVSHLNGGPTSIPFDDVKKLIDN
HHHHHCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCC
SDITLELVHNGNPKIMKQAAEYAMEKDCLDRFIIGNDAPSGTGVIVLSIIRVISFLSSVA
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHC
GIPPEKAICMATGNTSKVYDLNVGLIEKGREADFVIMDAPMGSVGEDSLTAFQEGDLPGV
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCE
SMVIVDGEVMFTKSRNTPPAVRMAEVQ
EEEEECCEEEEEECCCCCCCCEEECCC
>Mature Secondary Structure 
STLAIKNIGKLITGDLNNPVSEHDTIIVVNGKIKEIGGTELLNNYDLDKVVDAKGTTVA
CCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCEEECCCHHHHCCCCHHHHCCCCCCEEC
PGLIDSHAHPVLGDFTPRQKTMGFIESSLHGGVSTMISAGEPHTPGRPKGDKEGAKSLAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHH
LVHKSFNNLRPGGVKVHGGALILEKGLTEEDFKEVTREGVWLVGEVGLGTVKDPEEAAPM
HHHHHHHCCCCCCEEEECCEEEEECCCCHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
IEMAKNYGMKVMMHTGGTSIPGSSNVGYEDVINAKPTVVSHLNGGPTSIPFDDVKKLIDN
HHHHHCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCC
SDITLELVHNGNPKIMKQAAEYAMEKDCLDRFIIGNDAPSGTGVIVLSIIRVISFLSSVA
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHC
GIPPEKAICMATGNTSKVYDLNVGLIEKGREADFVIMDAPMGSVGEDSLTAFQEGDLPGV
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCE
SMVIVDGEVMFTKSRNTPPAVRMAEVQ
EEEEECCEEEEEECCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA