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The map label for this gene is pilC [H]

Identifier: 188586711

GI number: 188586711

Start: 2216754

End: 2217968

Strand: Reverse

Name: pilC [H]

Synonym: Nther_2101

Alternate gene names: 188586711

Gene position: 2217968-2216754 (Counterclockwise)

Preceding gene: 188586712

Following gene: 188586710

Centisome position: 70.07

GC content: 37.37

Gene sequence:

>1215_bases
ATGACCCCAAAATATTCATATAAAGCCAGGGATCCAAGTGGAAACCTGATCAAGGGTAGTCAAGAAACTGAGGACCGTCA
AAGCTTAATACAAGAATTAAAATCAGATCAGCTTTACATAGTTGAAATTAAACAGACAGGTAAAGAATTCAGTTTTAGTA
ATCTGAAAAAATATTTTCAAAAACCTGTAGCTTCCAGGGACCTGATGATTTTTTCTAGGCAGTTTGCCACTATGATCAAA
GCCGGGGTTACAGTGTTAGATAGTTTAGAGTCTTTGTCAGAGCAGATGGATAGCAAAAAATTGTCTCGAGGCCTGGTGAA
TGTGACAGAAAGTTTGAGAGGTGGTAATAGCCTGGCCGAATCGTTTCACGAACAAAAAGATGTGTTTCCCGAATTATTTG
TTAATATGATCAGTGCTGGTGAAGAAGCTGGTGCCCTTGAGGACGTTTTGGAACGAATGGCAGTTCACTATGAGAAGGAA
CATCAGCTTTTGGAAAAAATCAAAAGTGCCATGACGTATCCCGTAATACTTTTAGGAGTGGCCTTCTTAGTTGTATATTT
TTTAGTGACTTATGTACTGCCCGAATTTGCAGGGATTTTCGCAGGAATGGACGTAGAGCTTCCGTTATTAACTGAAATTA
TGTTATTTACTGGAAAAGCTTTAAGGGCCAATATACAATGGTTATTAATAATTTTAATTGTCCTAAGTTTAGCTGGCTAT
TATCTCTTGAATACCGATGGAGGAAAATATTTATATGACAAGGCAAAATTAACTTTACCAGTACTGGGAGGAGTTAGCAA
AAAAGTTATTATAGCCAGGTTTTCTCGTATTTTAACTACTCTGATTGGCAGTGGAATTACTTTAATGGATGCTTTAGGAT
TAGTTAAAAAAACTATTGGAAATAAGTTAATGGAAAAAGTCTTAGATGAGGCCGTGGATAATATAGAACAGGGACAGACC
ATGTCAAAACCCTTTGAGGAAAGTGAGTTATTTCCGCCTCTTGTGAGCAAGATGATGTCTGTAGGTGAGGAAACGGGAGC
AATTGAAGAGATGATGGATAAAGTAGCTGATTTTTATGAACAGGAAAGTAGTTATACTCTGGACAGGCTCAGTGCCCTGA
TAGAGCCGGTAATGATTTTAATTTTAATGGTTGTAGTAGCTGTGATAGTACTGGCAGTTGTATTACCTATGGTGGAAATG
TGGCAAATTTATTAA

Upstream 100 bases:

>100_bases
GTTGTTGTTGAACTCTTGGATTGAACGAATTCTGTAGGGTTGATATTACATATTTAACACAGTATAAATTTAGTGACTAT
CAATTATTGAGGTGAATCAG

Downstream 100 bases:

>100_bases
AATACATAACTCGAGTAATTGTTCAATGTATTGTTTCGATAAGATTGGGGGACTTCAAATGTTAAGGGGAAAGTTGATTC
CTGAACAGGTACCACTGGGA

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTPKYSYKARDPSGNLIKGSQETEDRQSLIQELKSDQLYIVEIKQTGKEFSFSNLKKYFQKPVASRDLMIFSRQFATMIK
AGVTVLDSLESLSEQMDSKKLSRGLVNVTESLRGGNSLAESFHEQKDVFPELFVNMISAGEEAGALEDVLERMAVHYEKE
HQLLEKIKSAMTYPVILLGVAFLVVYFLVTYVLPEFAGIFAGMDVELPLLTEIMLFTGKALRANIQWLLIILIVLSLAGY
YLLNTDGGKYLYDKAKLTLPVLGGVSKKVIIARFSRILTTLIGSGITLMDALGLVKKTIGNKLMEKVLDEAVDNIEQGQT
MSKPFEESELFPPLVSKMMSVGEETGAIEEMMDKVADFYEQESSYTLDRLSALIEPVMILILMVVVAVIVLAVVLPMVEM
WQIY

Sequences:

>Translated_404_residues
MTPKYSYKARDPSGNLIKGSQETEDRQSLIQELKSDQLYIVEIKQTGKEFSFSNLKKYFQKPVASRDLMIFSRQFATMIK
AGVTVLDSLESLSEQMDSKKLSRGLVNVTESLRGGNSLAESFHEQKDVFPELFVNMISAGEEAGALEDVLERMAVHYEKE
HQLLEKIKSAMTYPVILLGVAFLVVYFLVTYVLPEFAGIFAGMDVELPLLTEIMLFTGKALRANIQWLLIILIVLSLAGY
YLLNTDGGKYLYDKAKLTLPVLGGVSKKVIIARFSRILTTLIGSGITLMDALGLVKKTIGNKLMEKVLDEAVDNIEQGQT
MSKPFEESELFPPLVSKMMSVGEETGAIEEMMDKVADFYEQESSYTLDRLSALIEPVMILILMVVVAVIVLAVVLPMVEM
WQIY
>Mature_403_residues
TPKYSYKARDPSGNLIKGSQETEDRQSLIQELKSDQLYIVEIKQTGKEFSFSNLKKYFQKPVASRDLMIFSRQFATMIKA
GVTVLDSLESLSEQMDSKKLSRGLVNVTESLRGGNSLAESFHEQKDVFPELFVNMISAGEEAGALEDVLERMAVHYEKEH
QLLEKIKSAMTYPVILLGVAFLVVYFLVTYVLPEFAGIFAGMDVELPLLTEIMLFTGKALRANIQWLLIILIVLSLAGYY
LLNTDGGKYLYDKAKLTLPVLGGVSKKVIIARFSRILTTLIGSGITLMDALGLVKKTIGNKLMEKVLDEAVDNIEQGQTM
SKPFEESELFPPLVSKMMSVGEETGAIEEMMDKVADFYEQESSYTLDRLSALIEPVMILILMVVVAVIVLAVVLPMVEMW
QIY

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=397, Percent_Identity=25.4408060453401, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786295, Length=329, Percent_Identity=28.2674772036474, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45196; Mature: 45065

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPKYSYKARDPSGNLIKGSQETEDRQSLIQELKSDQLYIVEIKQTGKEFSFSNLKKYFQ
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHCCCCCCHHHHHHHHH
KPVASRDLMIFSRQFATMIKAGVTVLDSLESLSEQMDSKKLSRGLVNVTESLRGGNSLAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SFHEQKDVFPELFVNMISAGEEAGALEDVLERMAVHYEKEHQLLEKIKSAMTYPVILLGV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFLVVYFLVTYVLPEFAGIFAGMDVELPLLTEIMLFTGKALRANIQWLLIILIVLSLAGY
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
YLLNTDGGKYLYDKAKLTLPVLGGVSKKVIIARFSRILTTLIGSGITLMDALGLVKKTIG
EEEECCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NKLMEKVLDEAVDNIEQGQTMSKPFEESELFPPLVSKMMSVGEETGAIEEMMDKVADFYE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QESSYTLDRLSALIEPVMILILMVVVAVIVLAVVLPMVEMWQIY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]