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The map label for this gene is hppA [H]

Identifier: 188586623

GI number: 188586623

Start: 2122042

End: 2124003

Strand: Reverse

Name: hppA [H]

Synonym: Nther_2013

Alternate gene names: 188586623

Gene position: 2124003-2122042 (Counterclockwise)

Preceding gene: 188586624

Following gene: 188586622

Centisome position: 67.1

GC content: 41.95

Gene sequence:

>1962_bases
ATGAGCGCAGTAGCAGCACCAATTGCAGGAATTATAGGGTTAGTATTTGCTTTTTATTTGATCAATCAAGTGAACAAGCG
TGAAGAAGGCTCTGAAAGGATGCAGGAACTAGCTGCAGCCATTCAAGAGGGTGCCAGTGCATTCCTGCGTAGGGAATACC
GGAGTTTGGCAGTTTTTGTGATAGTATTGTTTGTTGTGATAACAATTGCTATTGATATACAAACTGCCATTTCCTTCTTA
GTAGGTGCCCTGTTTTCAGGTACAGCTGGTTTTATCGGTATGACTGTGGCTACTCGAGCTAATGTGAGAACAGCAAATGA
CGCACAGAATGAAGGGATTGCCCAAGCCCTAAGGACAGCCTTTTCAGGCGGGTCTGTCATGGGTATGTCTGTTGTAGGCT
TAGGTATTTTGGGTGTAGGAATCTTGTATTTGGTTTTTGAAGATCCTGAAATTGTTAATGGTTTTGCCTTAGGTGCTAGT
TCCATTGCATTATTCGCGCGTGTGGGCGGAGGTATATATACTAAAGCCGCCGATGTTGGAGCTGACCTTGTTGGTAAGGT
AGAAGCTGGCATTCCCGAAGATGATCCCAGGAACCCTGCGGCAATTGCCGACAATGTTGGTGATAATGTAGGGGACGTTG
CAGGAATGGGTGCAGATCTATTTGAATCCTTTGTAGGATCTATTATAGCAGCTATGACCATTGGCCTTGTCCAATATGGT
GTTGAAGGGGTTCTATTACCCATACTACTAGGATCAGTTGGAGTAATTGCTTCAATTATCGGCTATTTCTTTGTTAGAGT
CCGAGAAGGACAGAAACTAGCCTCTGCCTTAGAAAGAGGGACCATAGTTAGTGCTATTATAGTAGTGATTGCTGCCTTTA
TTTTAACTAACAATCTATTGGGAGAGTTAGGACCTTTTTACGCCATTTTAGCTGGCTTACTTGCTGGAATTTTAATTGGT
AGAATTACTGAATATTACACCTCAGAACATTATGCACCAGTAAAGGGAATTGCAGATTCTTCAAGAACAGGAGCAGCTAC
TAACATTATCAGTGGTATAGCTGTTGGAATGAAAAGTACTTTCTTACCCATTATCGTTATAACAGTAGCTATATTTATAG
CACATCAAGTTGCGGGCTTATACGGAATTGCTATAGCTGCTGTTGGAATGCTAGCAACAGTTGGTATGACAATTGCTGTT
GATGCTTACGGTCCTGTAGCTGATAACGCAGGTGGTATTGCAGAAATGGCTGATTTAGATCCTGAAGTACGAGAAATCAC
TGACGAGCTGGATGCAGTAGGGAACACTACTGCAGCAATTGGAAAAGGATTTGCCATCGGATCAGCAGCCCTAACAGCTC
TAGCATTATTTAGTGCATATACTCAAGCAGCAGATATTGATAATATTGACTTGACAAGTGCACCAGTAATTATTGGTCTA
TTGCTAGGCGGAATGTTACCATTCCTTTTCTCTGCTCTAACTATGAATGCCGTTGGCCAAGCTGCTAACCAGATGATAGA
CGAGGTTAGAAGACAAATTAAAGAAAAGCCGGGCATAATGGATGAAAAAGAAAAACCAGACTATGCAACTTGTGTTGATA
TTAGTACTGCAGCAGCTCTTAAGCAAATGGTATTACCAGGCTTACTTGCAGTTGTAGTACCATTATTGGTTGGATTATTG
CCAGGATTAGGTAAAGAAGCCCTAGGAGGTCTCCTAGCTGGAGCCTTGGCTTCTGGTGTTATGATGGCTATCTTTATGGC
AAACTCTGGTGGAGCTTGGGATAATGCTAAAAAGTACATTGAAGCTGGAAATCATGGTGGAAAAGGTACTGAGACTCATG
CAGCTTCAGTAGTAGGAGATACAGTTGGGGATCCCTTTAAAGACACTTCAGGCCCCAGTATCAATATTTTAATTAAGCTA
ATGACAATTGTTTCCTTAGTTTTTGCTCCCCTGTTTTTCTAA

Upstream 100 bases:

>100_bases
ACTTCTACGAAATAAGCGGTATTGTCGCTTGAATACCTCAACCAATAGGTTGAGGTAGTTTTTAGTACTACTAAAATACA
TATTTGAAGGGGGATAAGCC

Downstream 100 bases:

>100_bases
ATAAATATACGAAAGAATAACGATATTCAGACCACTAGAAGTGGTTATGTCAATAACCGGTCCGGCTTTTGCTTGGGCCG
GTTATTTATATATGAATTTA

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MSAVAAPIAGIIGLVFAFYLINQVNKREEGSERMQELAAAIQEGASAFLRREYRSLAVFVIVLFVVITIAIDIQTAISFL
VGALFSGTAGFIGMTVATRANVRTANDAQNEGIAQALRTAFSGGSVMGMSVVGLGILGVGILYLVFEDPEIVNGFALGAS
SIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAAIADNVGDNVGDVAGMGADLFESFVGSIIAAMTIGLVQYG
VEGVLLPILLGSVGVIASIIGYFFVRVREGQKLASALERGTIVSAIIVVIAAFILTNNLLGELGPFYAILAGLLAGILIG
RITEYYTSEHYAPVKGIADSSRTGAATNIISGIAVGMKSTFLPIIVITVAIFIAHQVAGLYGIAIAAVGMLATVGMTIAV
DAYGPVADNAGGIAEMADLDPEVREITDELDAVGNTTAAIGKGFAIGSAALTALALFSAYTQAADIDNIDLTSAPVIIGL
LLGGMLPFLFSALTMNAVGQAANQMIDEVRRQIKEKPGIMDEKEKPDYATCVDISTAAALKQMVLPGLLAVVVPLLVGLL
PGLGKEALGGLLAGALASGVMMAIFMANSGGAWDNAKKYIEAGNHGGKGTETHAASVVGDTVGDPFKDTSGPSINILIKL
MTIVSLVFAPLFF

Sequences:

>Translated_653_residues
MSAVAAPIAGIIGLVFAFYLINQVNKREEGSERMQELAAAIQEGASAFLRREYRSLAVFVIVLFVVITIAIDIQTAISFL
VGALFSGTAGFIGMTVATRANVRTANDAQNEGIAQALRTAFSGGSVMGMSVVGLGILGVGILYLVFEDPEIVNGFALGAS
SIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAAIADNVGDNVGDVAGMGADLFESFVGSIIAAMTIGLVQYG
VEGVLLPILLGSVGVIASIIGYFFVRVREGQKLASALERGTIVSAIIVVIAAFILTNNLLGELGPFYAILAGLLAGILIG
RITEYYTSEHYAPVKGIADSSRTGAATNIISGIAVGMKSTFLPIIVITVAIFIAHQVAGLYGIAIAAVGMLATVGMTIAV
DAYGPVADNAGGIAEMADLDPEVREITDELDAVGNTTAAIGKGFAIGSAALTALALFSAYTQAADIDNIDLTSAPVIIGL
LLGGMLPFLFSALTMNAVGQAANQMIDEVRRQIKEKPGIMDEKEKPDYATCVDISTAAALKQMVLPGLLAVVVPLLVGLL
PGLGKEALGGLLAGALASGVMMAIFMANSGGAWDNAKKYIEAGNHGGKGTETHAASVVGDTVGDPFKDTSGPSINILIKL
MTIVSLVFAPLFF
>Mature_652_residues
SAVAAPIAGIIGLVFAFYLINQVNKREEGSERMQELAAAIQEGASAFLRREYRSLAVFVIVLFVVITIAIDIQTAISFLV
GALFSGTAGFIGMTVATRANVRTANDAQNEGIAQALRTAFSGGSVMGMSVVGLGILGVGILYLVFEDPEIVNGFALGASS
IALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAAIADNVGDNVGDVAGMGADLFESFVGSIIAAMTIGLVQYGV
EGVLLPILLGSVGVIASIIGYFFVRVREGQKLASALERGTIVSAIIVVIAAFILTNNLLGELGPFYAILAGLLAGILIGR
ITEYYTSEHYAPVKGIADSSRTGAATNIISGIAVGMKSTFLPIIVITVAIFIAHQVAGLYGIAIAAVGMLATVGMTIAVD
AYGPVADNAGGIAEMADLDPEVREITDELDAVGNTTAAIGKGFAIGSAALTALALFSAYTQAADIDNIDLTSAPVIIGLL
LGGMLPFLFSALTMNAVGQAANQMIDEVRRQIKEKPGIMDEKEKPDYATCVDISTAAALKQMVLPGLLAVVVPLLVGLLP
GLGKEALGGLLAGALASGVMMAIFMANSGGAWDNAKKYIEAGNHGGKGTETHAASVVGDTVGDPFKDTSGPSINILIKLM
TIVSLVFAPLFF

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 66996; Mature: 66865

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVAAPIAGIIGLVFAFYLINQVNKREEGSERMQELAAAIQEGASAFLRREYRSLAVFV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLFVVITIAIDIQTAISFLVGALFSGTAGFIGMTVATRANVRTANDAQNEGIAQALRTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FSGGSVMGMSVVGLGILGVGILYLVFEDPEIVNGFALGASSIALFARVGGGIYTKAADVG
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
ADLVGKVEAGIPEDDPRNPAAIADNVGDNVGDVAGMGADLFESFVGSIIAAMTIGLVQYG
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VEGVLLPILLGSVGVIASIIGYFFVRVREGQKLASALERGTIVSAIIVVIAAFILTNNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GELGPFYAILAGLLAGILIGRITEYYTSEHYAPVKGIADSSRTGAATNIISGIAVGMKST
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
FLPIIVITVAIFIAHQVAGLYGIAIAAVGMLATVGMTIAVDAYGPVADNAGGIAEMADLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCHHHHHCC
PEVREITDELDAVGNTTAAIGKGFAIGSAALTALALFSAYTQAADIDNIDLTSAPVIIGL
HHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLGGMLPFLFSALTMNAVGQAANQMIDEVRRQIKEKPGIMDEKEKPDYATCVDISTAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
KQMVLPGLLAVVVPLLVGLLPGLGKEALGGLLAGALASGVMMAIFMANSGGAWDNAKKYI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EAGNHGGKGTETHAASVVGDTVGDPFKDTSGPSINILIKLMTIVSLVFAPLFF
HCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAVAAPIAGIIGLVFAFYLINQVNKREEGSERMQELAAAIQEGASAFLRREYRSLAVFV
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLFVVITIAIDIQTAISFLVGALFSGTAGFIGMTVATRANVRTANDAQNEGIAQALRTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FSGGSVMGMSVVGLGILGVGILYLVFEDPEIVNGFALGASSIALFARVGGGIYTKAADVG
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
ADLVGKVEAGIPEDDPRNPAAIADNVGDNVGDVAGMGADLFESFVGSIIAAMTIGLVQYG
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VEGVLLPILLGSVGVIASIIGYFFVRVREGQKLASALERGTIVSAIIVVIAAFILTNNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GELGPFYAILAGLLAGILIGRITEYYTSEHYAPVKGIADSSRTGAATNIISGIAVGMKST
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
FLPIIVITVAIFIAHQVAGLYGIAIAAVGMLATVGMTIAVDAYGPVADNAGGIAEMADLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCHHHHHCC
PEVREITDELDAVGNTTAAIGKGFAIGSAALTALALFSAYTQAADIDNIDLTSAPVIIGL
HHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLGGMLPFLFSALTMNAVGQAANQMIDEVRRQIKEKPGIMDEKEKPDYATCVDISTAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
KQMVLPGLLAVVVPLLVGLLPGLGKEALGGLLAGALASGVMMAIFMANSGGAWDNAKKYI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EAGNHGGKGTETHAASVVGDTVGDPFKDTSGPSINILIKLMTIVSLVFAPLFF
HCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA