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The map label for this gene is est [H]

Identifier: 188586622

GI number: 188586622

Start: 2121155

End: 2121898

Strand: Reverse

Name: est [H]

Synonym: Nther_2012

Alternate gene names: 188586622

Gene position: 2121898-2121155 (Counterclockwise)

Preceding gene: 188586623

Following gene: 188586621

Centisome position: 67.03

GC content: 35.08

Gene sequence:

>744_bases
GTGAGGATAATAAAGATTAAACCTCGGGTAGACAAAGAATTTTATTTGGAAGGTGAAAGTCAGTTAGGATGTTTGTTGGT
TCATGGGTTTACCGGGACTCCAGGGGAAATGGAGCCACTGGGAAACTATCTGAATAATTGTGGTTATACTGTATATGCAC
CACTATTAAGTGGTCATGGAACCACTCCTGAAGATTTGGCTGTTACTACGAAAGATCAAATCTTTGACTCAGCTTTCAGA
GGATTAGAAAGGTTGAAACACTGTCAAAAAGTTGTTGTTATAGGTTTATCAATGGGTGGCTTAATTTCCGGCCTGATTTC
CCTTAAAACTGAGATTGAAGGGCTTGTGTTAATGGGAACTCCGGTTTTCTTAGGAGATAGGAAAGCCTATTTGGCTCCTG
TTTTAAAATATATTAAACCATACATAAAAAAAATCAACAATAATGACTATCCTGTCACACCCACAAGTTATGACAGAACC
CCAGTATCGGGAATTTCAGAATTATTAAAATTAAGACATGAGTTTTTAGTATCTTTAAAAGAAATATCTGTTCCTACTTT
AATAATTCAAGGTATGAAAGATAATACTGTAAGGAGTGAAAGTGGTCGATACATTTATAATCATATTGGGAGTGAATCAG
CCAGTCTATTAGAGTTAGAAAACACACGACACATTGTAACTCTAGATATTGAACGGAAAGAAGCCTTTAGTACGATAGAT
AATTTTTTAACAGATTTGTTATAA

Upstream 100 bases:

>100_bases
GTTATGTCAATAACCGGTCCGGCTTTTGCTTGGGCCGGTTATTTATATATGAATTTAGGGAAGGAATTAAGCCCTTGTTA
GAAGAAATTAACTAGAGGGG

Downstream 100 bases:

>100_bases
TAGAGTATAACTAAGGGAAATTGGGTAATCTATGAAGTATAGATTGATTTTTTAATATGGGATTTTAGGAATGGTTAAGT
GAGTACAAACTCAGTCAAGT

Product: putative esterase/lipase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRIIKIKPRVDKEFYLEGESQLGCLLVHGFTGTPGEMEPLGNYLNNCGYTVYAPLLSGHGTTPEDLAVTTKDQIFDSAFR
GLERLKHCQKVVVIGLSMGGLISGLISLKTEIEGLVLMGTPVFLGDRKAYLAPVLKYIKPYIKKINNNDYPVTPTSYDRT
PVSGISELLKLRHEFLVSLKEISVPTLIIQGMKDNTVRSESGRYIYNHIGSESASLLELENTRHIVTLDIERKEAFSTID
NFLTDLL

Sequences:

>Translated_247_residues
MRIIKIKPRVDKEFYLEGESQLGCLLVHGFTGTPGEMEPLGNYLNNCGYTVYAPLLSGHGTTPEDLAVTTKDQIFDSAFR
GLERLKHCQKVVVIGLSMGGLISGLISLKTEIEGLVLMGTPVFLGDRKAYLAPVLKYIKPYIKKINNNDYPVTPTSYDRT
PVSGISELLKLRHEFLVSLKEISVPTLIIQGMKDNTVRSESGRYIYNHIGSESASLLELENTRHIVTLDIERKEAFSTID
NFLTDLL
>Mature_247_residues
MRIIKIKPRVDKEFYLEGESQLGCLLVHGFTGTPGEMEPLGNYLNNCGYTVYAPLLSGHGTTPEDLAVTTKDQIFDSAFR
GLERLKHCQKVVVIGLSMGGLISGLISLKTEIEGLVLMGTPVFLGDRKAYLAPVLKYIKPYIKKINNNDYPVTPTSYDRT
PVSGISELLKLRHEFLVSLKEISVPTLIIQGMKDNTVRSESGRYIYNHIGSESASLLELENTRHIVTLDIERKEAFSTID
NFLTDLL

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 27536; Mature: 27536

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIKIKPRVDKEFYLEGESQLGCLLVHGFTGTPGEMEPLGNYLNNCGYTVYAPLLSGHG
CEEEEECCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEHHHCCCC
TTPEDLAVTTKDQIFDSAFRGLERLKHCQKVVVIGLSMGGLISGLISLKTEIEGLVLMGT
CCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECC
PVFLGDRKAYLAPVLKYIKPYIKKINNNDYPVTPTSYDRTPVSGISELLKLRHEFLVSLK
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EISVPTLIIQGMKDNTVRSESGRYIYNHIGSESASLLELENTRHIVTLDIERKEAFSTID
HCCCCEEEEECCCCCCEECCCCCEEEECCCCCCCCEEEECCCCEEEEEEECHHHHHHHHH
NFLTDLL
HHHHHCC
>Mature Secondary Structure
MRIIKIKPRVDKEFYLEGESQLGCLLVHGFTGTPGEMEPLGNYLNNCGYTVYAPLLSGHG
CEEEEECCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEHHHCCCC
TTPEDLAVTTKDQIFDSAFRGLERLKHCQKVVVIGLSMGGLISGLISLKTEIEGLVLMGT
CCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECC
PVFLGDRKAYLAPVLKYIKPYIKKINNNDYPVTPTSYDRTPVSGISELLKLRHEFLVSLK
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EISVPTLIIQGMKDNTVRSESGRYIYNHIGSESASLLELENTRHIVTLDIERKEAFSTID
HCCCCEEEEECCCCCCEECCCCCEEEECCCCCCCCEEEECCCCEEEEEEECHHHHHHHHH
NFLTDLL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]