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The map label for this gene is kamA [H]

Identifier: 188586500

GI number: 188586500

Start: 1976279

End: 1977541

Strand: Direct

Name: kamA [H]

Synonym: Nther_1886

Alternate gene names: 188586500

Gene position: 1976279-1977541 (Clockwise)

Preceding gene: 188586490

Following gene: 188586501

Centisome position: 62.43

GC content: 35.95

Gene sequence:

>1263_bases
ATGTCTAAAACCAATCTAGAATCAATTCCAAAGTATAGTAATATTTCTGATTCAGAGTGGCAAAGCTGGGAATGGCAATT
AAATAATCGAATAACAGATGTAGAGAGCTTAAAAGAAATCATCAATCTAACTGAGGAGGAAGAGGAAGGTATCAAGCAAA
CCTTAAAAACAATTAGGATGGCTATCACCCCTTACTATGCATCATTAATGGATAAAGATGACCCAAGCTGTCCCATCAGA
AGACACGCAGTACCTAGTTCTCTTGAACTTAATTTTTCTGAGTTTGATTTAGAAGATCCGTTAAGTGAGGATTCCGATTC
TCCAGTTGAAGGTATTACTCACCGTTACCCAGATCGTGTTCTATTTTTGGTAACAGATCAGTGCTCAATGTACTGTAGGC
ACTGTACTAGAAGAAGATTAGCCGGTTCTACTGATAAAGCTGCCCCTATCGAAGTTATTGATAAAGCCATCGATTATATT
AAAAATACTCCTCAAGTAAGGGATGTATTAATTTCAGGTGGAGATGGATTATTAATTTCAGATGAAAGATTAGAATATAT
CTTGAATGAACTTTATAAAATTGAACACGTTGAAATCGTTAGAATTGGTACTCGTGCACCTGTGGTATTACCCCAGAGAA
TTACAGATAATTTAATAAGTATATTGAAAAAATATCATCCTATTTGGTTAAATACTCACTTCAATCATCCAAAAGAAATA
ACATCGGAAGCTAAGGAAGCCTTGGCTAAACTTGCAGATGCTGGAATTCCCCTTGGAAACCAATCTGTATTGTTAAGAGG
AATTAATGATTGTCCTGTTACAATGAAAGAACTTGTTCACGAACTTGTTAAAAACAGAGTGAGACCTTATTATATTTATC
AATGTGACCTATCCCAGGGAATAGAGCACTTTAGAACCTCTGTTTCCGCTGGTCTAGAAATTATAGAATCATTAAGAGGT
CATACTAGTGGTTATGCAGTACCTACCTTTGTTGTGGATGCTCCAGGAGGTGGAGGAAAAACTCCAGTAATGCCGCAGTA
TTTAATCTCTCAATCACCAGACAGTGTAGTTTTAAGGAATTATGAAGGAGTTATTTCTAAATATTCCGAACCTAAAGATA
AAACTAAAGGATGTGGCAAGGAAAGCTGTACAGATTGTGAACATATCGGACAAGATTCCACTGGAGTTTCTGCATTAATG
AGCGGGAATGAAATTAGTCTAGAACCCAGTAATTTAAGACGATTAAATCGACGAAATAAATAA

Upstream 100 bases:

>100_bases
TTTTAAATTTCAGTACTATGTTTGTCTATTGGCATGAAAATTGCATATGTTTAAATTATGAACAATAAGTATAGTCACAT
AAATTGAAAGGAGAGATAAC

Downstream 100 bases:

>100_bases
TTTTAGTTTATACAGAATGGAACCGATAATTATTTTGTAGGGTATCCTTAACTTTTTAAACCTTTTACAAGGCTTTATCT
TTTGAAGGATACCCTACTTT

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSKTNLESIPKYSNISDSEWQSWEWQLNNRITDVESLKEIINLTEEEEEGIKQTLKTIRMAITPYYASLMDKDDPSCPIR
RHAVPSSLELNFSEFDLEDPLSEDSDSPVEGITHRYPDRVLFLVTDQCSMYCRHCTRRRLAGSTDKAAPIEVIDKAIDYI
KNTPQVRDVLISGGDGLLISDERLEYILNELYKIEHVEIVRIGTRAPVVLPQRITDNLISILKKYHPIWLNTHFNHPKEI
TSEAKEALAKLADAGIPLGNQSVLLRGINDCPVTMKELVHELVKNRVRPYYIYQCDLSQGIEHFRTSVSAGLEIIESLRG
HTSGYAVPTFVVDAPGGGGKTPVMPQYLISQSPDSVVLRNYEGVISKYSEPKDKTKGCGKESCTDCEHIGQDSTGVSALM
SGNEISLEPSNLRRLNRRNK

Sequences:

>Translated_420_residues
MSKTNLESIPKYSNISDSEWQSWEWQLNNRITDVESLKEIINLTEEEEEGIKQTLKTIRMAITPYYASLMDKDDPSCPIR
RHAVPSSLELNFSEFDLEDPLSEDSDSPVEGITHRYPDRVLFLVTDQCSMYCRHCTRRRLAGSTDKAAPIEVIDKAIDYI
KNTPQVRDVLISGGDGLLISDERLEYILNELYKIEHVEIVRIGTRAPVVLPQRITDNLISILKKYHPIWLNTHFNHPKEI
TSEAKEALAKLADAGIPLGNQSVLLRGINDCPVTMKELVHELVKNRVRPYYIYQCDLSQGIEHFRTSVSAGLEIIESLRG
HTSGYAVPTFVVDAPGGGGKTPVMPQYLISQSPDSVVLRNYEGVISKYSEPKDKTKGCGKESCTDCEHIGQDSTGVSALM
SGNEISLEPSNLRRLNRRNK
>Mature_419_residues
SKTNLESIPKYSNISDSEWQSWEWQLNNRITDVESLKEIINLTEEEEEGIKQTLKTIRMAITPYYASLMDKDDPSCPIRR
HAVPSSLELNFSEFDLEDPLSEDSDSPVEGITHRYPDRVLFLVTDQCSMYCRHCTRRRLAGSTDKAAPIEVIDKAIDYIK
NTPQVRDVLISGGDGLLISDERLEYILNELYKIEHVEIVRIGTRAPVVLPQRITDNLISILKKYHPIWLNTHFNHPKEIT
SEAKEALAKLADAGIPLGNQSVLLRGINDCPVTMKELVHELVKNRVRPYYIYQCDLSQGIEHFRTSVSAGLEIIESLRGH
TSGYAVPTFVVDAPGGGGKTPVMPQYLISQSPDSVVLRNYEGVISKYSEPKDKTKGCGKESCTDCEHIGQDSTGVSALMS
GNEISLEPSNLRRLNRRNK

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=325, Percent_Identity=32.6153846153846, Blast_Score=178, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 47304; Mature: 47173

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTNLESIPKYSNISDSEWQSWEWQLNNRITDVESLKEIINLTEEEEEGIKQTLKTIRM
CCCCCCHHCCCCCCCCCCCCCCHHEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
AITPYYASLMDKDDPSCPIRRHAVPSSLELNFSEFDLEDPLSEDSDSPVEGITHRYPDRV
HHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCCEE
LFLVTDQCSMYCRHCTRRRLAGSTDKAAPIEVIDKAIDYIKNTPQVRDVLISGGDGLLIS
EEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHEEECCCCEEEC
DERLEYILNELYKIEHVEIVRIGTRAPVVLPQRITDNLISILKKYHPIWLNTHFNHPKEI
HHHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCEEEECCCCCHHHH
TSEAKEALAKLADAGIPLGNQSVLLRGINDCPVTMKELVHELVKNRVRPYYIYQCDLSQG
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHH
IEHFRTSVSAGLEIIESLRGHTSGYAVPTFVVDAPGGGGKTPVMPQYLISQSPDSVVLRN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHCCCCCCEEHHH
YEGVISKYSEPKDKTKGCGKESCTDCEHIGQDSTGVSALMSGNEISLEPSNLRRLNRRNK
HHHHHHHCCCCCHHHCCCCCCCCCCHHHCCCCCCCHHHHCCCCEEEECHHHHHHHHCCCC
>Mature Secondary Structure 
SKTNLESIPKYSNISDSEWQSWEWQLNNRITDVESLKEIINLTEEEEEGIKQTLKTIRM
CCCCCHHCCCCCCCCCCCCCCHHEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
AITPYYASLMDKDDPSCPIRRHAVPSSLELNFSEFDLEDPLSEDSDSPVEGITHRYPDRV
HHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCCEE
LFLVTDQCSMYCRHCTRRRLAGSTDKAAPIEVIDKAIDYIKNTPQVRDVLISGGDGLLIS
EEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHEEECCCCEEEC
DERLEYILNELYKIEHVEIVRIGTRAPVVLPQRITDNLISILKKYHPIWLNTHFNHPKEI
HHHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCEEEECCCCCHHHH
TSEAKEALAKLADAGIPLGNQSVLLRGINDCPVTMKELVHELVKNRVRPYYIYQCDLSQG
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHH
IEHFRTSVSAGLEIIESLRGHTSGYAVPTFVVDAPGGGGKTPVMPQYLISQSPDSVVLRN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHCCCCCCEEHHH
YEGVISKYSEPKDKTKGCGKESCTDCEHIGQDSTGVSALMSGNEISLEPSNLRRLNRRNK
HHHHHHHCCCCCHHHCCCCCCCCCCHHHCCCCCCCHHHHCCCCEEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]