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The map label for this gene is spoVK [H]

Identifier: 188586127

GI number: 188586127

Start: 1575888

End: 1576853

Strand: Direct

Name: spoVK [H]

Synonym: Nther_1502

Alternate gene names: 188586127

Gene position: 1575888-1576853 (Clockwise)

Preceding gene: 188586126

Following gene: 188586128

Centisome position: 49.78

GC content: 34.16

Gene sequence:

>966_bases
ATGGTAAAGATAAATATAAATGGGAAAACCGAAGATAGTGATCAATACATTCTTTCTCATGAATCAATGGCCAAAGATAA
TTCAAAAGTATTTAATAATGAAAATTCAGGGATTAACAGCAATGGAGAAAGCTTTTTTCATCTAAGTGATAATGTACTAA
GAAGTCTAAATAAAATGGAACGATTGGTGGGTCTGGAAAAAGTCAAACGCAATATTTATGAGATATGTGCATATATAGCA
ATCCAGAATAAAAGGCAGCAGCTAAATTTATCAGTCGAATCACAGACTTTGCACATGCTTTTTATGGGATCTCCAGGGAC
AGGTAAAACTACAGTAGCAAGAATACTAGGAGAAATCTTTAAAGAACTTGATTATCTTCCATCAGGTCACTTAGTGGAAG
TCGAGAGGGCCGATTTGGTAGGCGAGTATATTGGCCAGACTGCTCAAAAGACTAAAAAACAAATTGACAATGCACTGGGA
GGAATTTTGTTCATTGACGAGGCTTATGCTCTTGCACGAGGTGGCAGTACTGATTTTGGGAAAGAAGCTATAGATACTTT
GGTGAAATCCATGGAAGACTATAAAGACCGCCTAGTTGTAATATTAGCAGGCTATAAAGATGAAATGAAATTATTTCTAA
AATCTAATCCCGGCTTATCTAGTAGATTTCCTATTCATATTGAGTTTCCCAATTATACTGGGGAACAATTGCTTGCTATT
GCTGAGAAAATGCTAGAAGAAAGACAATACTATATGGATAAAGTCGCTAGGAAATATTTATTTGAAATAATAAATTCTGA
ATTATCTCAAAGGGAAATAAACTTTTCCAATGCCCGTTTTATCCGTAATCTAATAGAGAAAAGTATCCGAAGACAGGCGA
TTAGACTAATCAATAAGGAAAAAATCAAAAAAAATGACTTAATTTATCTAAAAGCCGAAGATATTGATCATCCTGGCTCT
TCATAA

Upstream 100 bases:

>100_bases
TTACGAATTTAATATTAACTTTTTTATTTGATATTACGTACAATAAAATAGAGTTATCTAATTTTTGAACCACGCCATCA
AAAAGGTGGTGGTTTTATTT

Downstream 100 bases:

>100_bases
TTTGACAATATCAAATAACAATAGATAAAATTCATAATATATGCCATGATATAAATAGAAAAAATGCCAATAATTGCTGA
GATTTGCGCTTACCCGGGAA

Product: AAA ATPase central domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVKININGKTEDSDQYILSHESMAKDNSKVFNNENSGINSNGESFFHLSDNVLRSLNKMERLVGLEKVKRNIYEICAYIA
IQNKRQQLNLSVESQTLHMLFMGSPGTGKTTVARILGEIFKELDYLPSGHLVEVERADLVGEYIGQTAQKTKKQIDNALG
GILFIDEAYALARGGSTDFGKEAIDTLVKSMEDYKDRLVVILAGYKDEMKLFLKSNPGLSSRFPIHIEFPNYTGEQLLAI
AEKMLEERQYYMDKVARKYLFEIINSELSQREINFSNARFIRNLIEKSIRRQAIRLINKEKIKKNDLIYLKAEDIDHPGS
S

Sequences:

>Translated_321_residues
MVKININGKTEDSDQYILSHESMAKDNSKVFNNENSGINSNGESFFHLSDNVLRSLNKMERLVGLEKVKRNIYEICAYIA
IQNKRQQLNLSVESQTLHMLFMGSPGTGKTTVARILGEIFKELDYLPSGHLVEVERADLVGEYIGQTAQKTKKQIDNALG
GILFIDEAYALARGGSTDFGKEAIDTLVKSMEDYKDRLVVILAGYKDEMKLFLKSNPGLSSRFPIHIEFPNYTGEQLLAI
AEKMLEERQYYMDKVARKYLFEIINSELSQREINFSNARFIRNLIEKSIRRQAIRLINKEKIKKNDLIYLKAEDIDHPGS
S
>Mature_321_residues
MVKININGKTEDSDQYILSHESMAKDNSKVFNNENSGINSNGESFFHLSDNVLRSLNKMERLVGLEKVKRNIYEICAYIA
IQNKRQQLNLSVESQTLHMLFMGSPGTGKTTVARILGEIFKELDYLPSGHLVEVERADLVGEYIGQTAQKTKKQIDNALG
GILFIDEAYALARGGSTDFGKEAIDTLVKSMEDYKDRLVVILAGYKDEMKLFLKSNPGLSSRFPIHIEFPNYTGEQLLAI
AEKMLEERQYYMDKVARKYLFEIINSELSQREINFSNARFIRNLIEKSIRRQAIRLINKEKIKKNDLIYLKAEDIDHPGS
S

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR014232 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36644; Mature: 36644

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKININGKTEDSDQYILSHESMAKDNSKVFNNENSGINSNGESFFHLSDNVLRSLNKME
CEEEEECCCCCCCCCEEECHHHHCCCCCHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
RLVGLEKVKRNIYEICAYIAIQNKRQQLNLSVESQTLHMLFMGSPGTGKTTVARILGEIF
HHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHH
KELDYLPSGHLVEVERADLVGEYIGQTAQKTKKQIDNALGGILFIDEAYALARGGSTDFG
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCCCCH
KEAIDTLVKSMEDYKDRLVVILAGYKDEMKLFLKSNPGLSSRFPIHIEFPNYTGEQLLAI
HHHHHHHHHHHHHHHCEEEEEEECCCHHHEEEEECCCCCCCCCCEEEECCCCCHHHHHHH
AEKMLEERQYYMDKVARKYLFEIINSELSQREINFSNARFIRNLIEKSIRRQAIRLINKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIKKNDLIYLKAEDIDHPGSS
HCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MVKININGKTEDSDQYILSHESMAKDNSKVFNNENSGINSNGESFFHLSDNVLRSLNKME
CEEEEECCCCCCCCCEEECHHHHCCCCCHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
RLVGLEKVKRNIYEICAYIAIQNKRQQLNLSVESQTLHMLFMGSPGTGKTTVARILGEIF
HHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHH
KELDYLPSGHLVEVERADLVGEYIGQTAQKTKKQIDNALGGILFIDEAYALARGGSTDFG
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCCCCH
KEAIDTLVKSMEDYKDRLVVILAGYKDEMKLFLKSNPGLSSRFPIHIEFPNYTGEQLLAI
HHHHHHHHHHHHHHHCEEEEEEECCCHHHEEEEECCCCCCCCCCEEEECCCCCHHHHHHH
AEKMLEERQYYMDKVARKYLFEIINSELSQREINFSNARFIRNLIEKSIRRQAIRLINKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIKKNDLIYLKAEDIDHPGSS
HCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1787791; 9384377 [H]