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The map label for this gene is ftsK [H]

Identifier: 188586091

GI number: 188586091

Start: 1535498

End: 1537966

Strand: Direct

Name: ftsK [H]

Synonym: Nther_1465

Alternate gene names: 188586091

Gene position: 1535498-1537966 (Clockwise)

Preceding gene: 188586090

Following gene: 188586092

Centisome position: 48.51

GC content: 36.61

Gene sequence:

>2469_bases
GTGGTAGCTAAAAAAACTAACAAAAAGCAAAGAAAAAAATCGAACAAAGGTTTAAAAACTACACCAGAATTACAAGCTGG
CTTGTTACTTTTATTTGCAATCATTTCCCTAGCGAGCTTAGTTTTTACTGAACAAACTGGGGTTTTAGGAAATATTATCA
AAGTTGTTTTCGAATACTTAGCTGGTGAACGAGCTTGGACTATTCCTATATTTATTGCCATTTTAGGTGGTAATTTACTG
TATTTGAAAAGTATTCAACTCACAAACAGGTTTTGGGGTATTAGTTTAGTTTTATTTCTTATTGTAGTTGGACATCATAT
TGAACTAATTTTACAGGAAAATATTATTAGTAGAGGAGAAATAGTAGCACAAGCTTTTAGTTTGCCTGCTGAAGGTGCCG
GTGGCGGATTGATGGGGGCTATTTTCTCTACTGCATTTTTACTTGTCCTAGGTGAAATTGGGACTTTTATTGTTTTGATT
TTTACTGGTATCATAGCCTTTATGTTGTTGACAGACACTACTTTCAAAGAAGGACTTAGCTTGGGGACAGGAGCTGCTAA
AAAAGCGTGGGAACTGGTTCTATTAGCAAATGAAAAATTGATTGAGATTTATAATCGAATTTCTAATACCAAACAAATGA
AAGAGTATCAAAAGGGACAAGTTAAAAATGAAGATGATACAAATATATTAGATTTTAATGACTATAAACAAGGTCGGCAA
GAGGAGGAAGATCAAGGATCTTTGCAAGCTACTGGGGGGACTTATCAGGACGAGCCTGACTATCCTATTGTTAGCTTTGA
AGAAAATGAGGCAGGACTGCAAGCCAAAATAACTGAGAGTAAGGAAGAAGCTAATAATAGCGAACCAGGCCCAGAGGACA
AAAGAGAAGGTCAGAAATCAAGTCAAAAAAGTGGATCAATACAATCAAACACAAATACTGGTTCTGAAACTTTAGCTCAA
GAAAGTTTTAGTGATGGGCATGGCAGTGACAATCAAGAAAAGGACAAAGTAGTATCCTATACTTTTTATCCCAATGAGTC
CCTCGGTAACTATAAACTGCCACCTTTAAACTTGTTAAAAAAATCTACAGGAGAGCAGGGAGATAAAACAGATAAAAGGG
AACTCTCCGATAGAGCCAGATTATTAGAAGAAACCCTGGCTTCCTTCGGGGTAAAAGCCCGAGTAATTAAAGTTCAAAAA
GGACCAACTATTACTCGCTTTGAATTACAACCGGAAAAGGGTGTTAAAGTGAGTAAAATAGTTAATTTGTCCGATGATTT
GGCTCTAAGCTTAGCTGCTTCGGAAATTAGGATAGAAGCACCTATCCCAGGCAAAGCCGCTATAGGCATTGAAATTCCTA
ATAAAGTTATTTCACCAGTTTACTTAAGAGAAGTATTAGAAAGTCCTAATTTCCAAAAAAGTGAATCTCCATTATCAATT
GCTATTGGTAAAGATATAGCTGGAGAACCAGTGGTAGCAGACCTGGCCAAGATGCCTCACCTTTTAATAGCAGGTGCAAC
TGGGTCAGGTAAAAGTGTCAGTATTAATACGTTGATTGCTAGTATCCTTTATAAAGCCAAACCTGACGAGGTTAAATTAC
TATTGATCGATCCCAAGGTAGTAGAACTAAAATCCTTTGATGGACTTCCACATTTGTTGGCACCAGTAGTAACAAATCCT
AAAAATGCCGCTAGTACTTTAAAAAATATCGTGAGCGAAATGGAGTACAGATATCAGTTATTTGCAGATACAGGTGTTAG
AGATATAGCAAAATATAATGCAATAAATAAGGAAGAAGATTATCCGGAGAAACTACCTTATATTGTAGTGATTATTGACG
AACTGGCCGATCTCATGATGGTTGCTCCTACAGAAGTTGAAGATGGGATTTTTAGATTAGCTCAAATGTCAAGAGCAGCG
GGCATTCATTTAATTTTAGCAACACAACGTCCATCTGTGGATGTAATTACAGGTGTAATCAAATCTAATATAACTTCAAG
AATTGCTTTTGCTGTAACTTCTCAAGCTGATTCTAGAACCATCTTGGATATGGGGGGAGCGGAAAAATTACTGGGACAAG
GTGATATGTTATTTACTCCTATGGGTAGTAATAAACCTATTAGATTACAAGGTGCTTTTATTTCAGATAAGGAGATTGAT
GAGCTCGCCGAAAAAGTAAAAGAACAAGCTGAACCTCAATATCAGGAGGAATTAGTAACAACAACTCCGGAAACTGACAA
AAAGCAAGAATACGATGAGTTGTTGCCCAAGGCAGTAGAATTGGTTATGGAAACTCAGCAAGCATCAATTTCATTAATTC
AAAGAAGATTAAGGGTGGGTTATACTAGGGCAGCACGTTTGATAGATGAACTAGAAGAATTTGGTGTAATTGGCGGACAT
GAAGGCAGCAAGCCTCGCAGAATATTAATGACAGAAGAAGATATTAAAAACATTTTAGAACAATTGTAG

Upstream 100 bases:

>100_bases
AATCAATATGTTATTGGATTGTTTACAGATAATACAAATAATCAGTTCTAAATTTGGCAATAATGAGAGTTACTGGTATA
ATTAGGTCGAGGTGAAAATA

Downstream 100 bases:

>100_bases
CAGGCCATAATAAGGCCTGCTTTTTTCTGTAATATGATGCAGGAAAACAGATATCATTTCAAGAAATACTTAATTCGAGA
ATTATATTATTGTAAATACT

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MVAKKTNKKQRKKSNKGLKTTPELQAGLLLLFAIISLASLVFTEQTGVLGNIIKVVFEYLAGERAWTIPIFIAILGGNLL
YLKSIQLTNRFWGISLVLFLIVVGHHIELILQENIISRGEIVAQAFSLPAEGAGGGLMGAIFSTAFLLVLGEIGTFIVLI
FTGIIAFMLLTDTTFKEGLSLGTGAAKKAWELVLLANEKLIEIYNRISNTKQMKEYQKGQVKNEDDTNILDFNDYKQGRQ
EEEDQGSLQATGGTYQDEPDYPIVSFEENEAGLQAKITESKEEANNSEPGPEDKREGQKSSQKSGSIQSNTNTGSETLAQ
ESFSDGHGSDNQEKDKVVSYTFYPNESLGNYKLPPLNLLKKSTGEQGDKTDKRELSDRARLLEETLASFGVKARVIKVQK
GPTITRFELQPEKGVKVSKIVNLSDDLALSLAASEIRIEAPIPGKAAIGIEIPNKVISPVYLREVLESPNFQKSESPLSI
AIGKDIAGEPVVADLAKMPHLLIAGATGSGKSVSINTLIASILYKAKPDEVKLLLIDPKVVELKSFDGLPHLLAPVVTNP
KNAASTLKNIVSEMEYRYQLFADTGVRDIAKYNAINKEEDYPEKLPYIVVIIDELADLMMVAPTEVEDGIFRLAQMSRAA
GIHLILATQRPSVDVITGVIKSNITSRIAFAVTSQADSRTILDMGGAEKLLGQGDMLFTPMGSNKPIRLQGAFISDKEID
ELAEKVKEQAEPQYQEELVTTTPETDKKQEYDELLPKAVELVMETQQASISLIQRRLRVGYTRAARLIDELEEFGVIGGH
EGSKPRRILMTEEDIKNILEQL

Sequences:

>Translated_822_residues
MVAKKTNKKQRKKSNKGLKTTPELQAGLLLLFAIISLASLVFTEQTGVLGNIIKVVFEYLAGERAWTIPIFIAILGGNLL
YLKSIQLTNRFWGISLVLFLIVVGHHIELILQENIISRGEIVAQAFSLPAEGAGGGLMGAIFSTAFLLVLGEIGTFIVLI
FTGIIAFMLLTDTTFKEGLSLGTGAAKKAWELVLLANEKLIEIYNRISNTKQMKEYQKGQVKNEDDTNILDFNDYKQGRQ
EEEDQGSLQATGGTYQDEPDYPIVSFEENEAGLQAKITESKEEANNSEPGPEDKREGQKSSQKSGSIQSNTNTGSETLAQ
ESFSDGHGSDNQEKDKVVSYTFYPNESLGNYKLPPLNLLKKSTGEQGDKTDKRELSDRARLLEETLASFGVKARVIKVQK
GPTITRFELQPEKGVKVSKIVNLSDDLALSLAASEIRIEAPIPGKAAIGIEIPNKVISPVYLREVLESPNFQKSESPLSI
AIGKDIAGEPVVADLAKMPHLLIAGATGSGKSVSINTLIASILYKAKPDEVKLLLIDPKVVELKSFDGLPHLLAPVVTNP
KNAASTLKNIVSEMEYRYQLFADTGVRDIAKYNAINKEEDYPEKLPYIVVIIDELADLMMVAPTEVEDGIFRLAQMSRAA
GIHLILATQRPSVDVITGVIKSNITSRIAFAVTSQADSRTILDMGGAEKLLGQGDMLFTPMGSNKPIRLQGAFISDKEID
ELAEKVKEQAEPQYQEELVTTTPETDKKQEYDELLPKAVELVMETQQASISLIQRRLRVGYTRAARLIDELEEFGVIGGH
EGSKPRRILMTEEDIKNILEQL
>Mature_822_residues
MVAKKTNKKQRKKSNKGLKTTPELQAGLLLLFAIISLASLVFTEQTGVLGNIIKVVFEYLAGERAWTIPIFIAILGGNLL
YLKSIQLTNRFWGISLVLFLIVVGHHIELILQENIISRGEIVAQAFSLPAEGAGGGLMGAIFSTAFLLVLGEIGTFIVLI
FTGIIAFMLLTDTTFKEGLSLGTGAAKKAWELVLLANEKLIEIYNRISNTKQMKEYQKGQVKNEDDTNILDFNDYKQGRQ
EEEDQGSLQATGGTYQDEPDYPIVSFEENEAGLQAKITESKEEANNSEPGPEDKREGQKSSQKSGSIQSNTNTGSETLAQ
ESFSDGHGSDNQEKDKVVSYTFYPNESLGNYKLPPLNLLKKSTGEQGDKTDKRELSDRARLLEETLASFGVKARVIKVQK
GPTITRFELQPEKGVKVSKIVNLSDDLALSLAASEIRIEAPIPGKAAIGIEIPNKVISPVYLREVLESPNFQKSESPLSI
AIGKDIAGEPVVADLAKMPHLLIAGATGSGKSVSINTLIASILYKAKPDEVKLLLIDPKVVELKSFDGLPHLLAPVVTNP
KNAASTLKNIVSEMEYRYQLFADTGVRDIAKYNAINKEEDYPEKLPYIVVIIDELADLMMVAPTEVEDGIFRLAQMSRAA
GIHLILATQRPSVDVITGVIKSNITSRIAFAVTSQADSRTILDMGGAEKLLGQGDMLFTPMGSNKPIRLQGAFISDKEID
ELAEKVKEQAEPQYQEELVTTTPETDKKQEYDELLPKAVELVMETQQASISLIQRRLRVGYTRAARLIDELEEFGVIGGH
EGSKPRRILMTEEDIKNILEQL

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=483, Percent_Identity=49.4824016563147, Blast_Score=447, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 90294; Mature: 90294

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKKTNKKQRKKSNKGLKTTPELQAGLLLLFAIISLASLVFTEQTGVLGNIIKVVFEYL
CCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AGERAWTIPIFIAILGGNLLYLKSIQLTNRFWGISLVLFLIVVGHHIELILQENIISRGE
CCCCCEEHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVAQAFSLPAEGAGGGLMGAIFSTAFLLVLGEIGTFIVLIFTGIIAFMLLTDTTFKEGLS
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
LGTGAAKKAWELVLLANEKLIEIYNRISNTKQMKEYQKGQVKNEDDTNILDFNDYKQGRQ
CCCCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHCCCC
EEEDQGSLQATGGTYQDEPDYPIVSFEENEAGLQAKITESKEEANNSEPGPEDKREGQKS
CCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCHHHCCCCCCCCCHHHHCHHH
SQKSGSIQSNTNTGSETLAQESFSDGHGSDNQEKDKVVSYTFYPNESLGNYKLPPLNLLK
HHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
KSTGEQGDKTDKRELSDRARLLEETLASFGVKARVIKVQKGPTITRFELQPEKGVKVSKI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHE
VNLSDDLALSLAASEIRIEAPIPGKAAIGIEIPNKVISPVYLREVLESPNFQKSESPLSI
ECCCCHHHHEEEHEEEEEECCCCCCEEEEEECCHHHHCHHHHHHHHCCCCCCCCCCCEEE
AIGKDIAGEPVVADLAKMPHLLIAGATGSGKSVSINTLIASILYKAKPDEVKLLLIDPKV
EECCCCCCCHHHHHHHHCCEEEEEECCCCCCCEEHHHHHHHHHHCCCCCCEEEEEECCCE
VELKSFDGLPHLLAPVVTNPKNAASTLKNIVSEMEYRYQLFADTGVRDIAKYNAINKEED
EEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
YPEKLPYIVVIIDELADLMMVAPTEVEDGIFRLAQMSRAAGIHLILATQRPSVDVITGVI
CHHHCCEEEEEHHHHHHHHEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
KSNITSRIAFAVTSQADSRTILDMGGAEKLLGQGDMLFTPMGSNKPIRLQGAFISDKEID
HHHHHHHEEEEEECCCCCCEEEECCCHHHHHCCCCEEEEECCCCCCEEEEECCCCCHHHH
ELAEKVKEQAEPQYQEELVTTTPETDKKQEYDELLPKAVELVMETQQASISLIQRRLRVG
HHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTRAARLIDELEEFGVIGGHEGSKPRRILMTEEDIKNILEQL
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHC
>Mature Secondary Structure
MVAKKTNKKQRKKSNKGLKTTPELQAGLLLLFAIISLASLVFTEQTGVLGNIIKVVFEYL
CCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AGERAWTIPIFIAILGGNLLYLKSIQLTNRFWGISLVLFLIVVGHHIELILQENIISRGE
CCCCCEEHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVAQAFSLPAEGAGGGLMGAIFSTAFLLVLGEIGTFIVLIFTGIIAFMLLTDTTFKEGLS
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
LGTGAAKKAWELVLLANEKLIEIYNRISNTKQMKEYQKGQVKNEDDTNILDFNDYKQGRQ
CCCCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHCCCC
EEEDQGSLQATGGTYQDEPDYPIVSFEENEAGLQAKITESKEEANNSEPGPEDKREGQKS
CCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCHHHCCCCCCCCCHHHHCHHH
SQKSGSIQSNTNTGSETLAQESFSDGHGSDNQEKDKVVSYTFYPNESLGNYKLPPLNLLK
HHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
KSTGEQGDKTDKRELSDRARLLEETLASFGVKARVIKVQKGPTITRFELQPEKGVKVSKI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHE
VNLSDDLALSLAASEIRIEAPIPGKAAIGIEIPNKVISPVYLREVLESPNFQKSESPLSI
ECCCCHHHHEEEHEEEEEECCCCCCEEEEEECCHHHHCHHHHHHHHCCCCCCCCCCCEEE
AIGKDIAGEPVVADLAKMPHLLIAGATGSGKSVSINTLIASILYKAKPDEVKLLLIDPKV
EECCCCCCCHHHHHHHHCCEEEEEECCCCCCCEEHHHHHHHHHHCCCCCCEEEEEECCCE
VELKSFDGLPHLLAPVVTNPKNAASTLKNIVSEMEYRYQLFADTGVRDIAKYNAINKEED
EEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
YPEKLPYIVVIIDELADLMMVAPTEVEDGIFRLAQMSRAAGIHLILATQRPSVDVITGVI
CHHHCCEEEEEHHHHHHHHEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
KSNITSRIAFAVTSQADSRTILDMGGAEKLLGQGDMLFTPMGSNKPIRLQGAFISDKEID
HHHHHHHEEEEEECCCCCCEEEECCCHHHHHCCCCEEEEECCCCCCEEEEECCCCCHHHH
ELAEKVKEQAEPQYQEELVTTTPETDKKQEYDELLPKAVELVMETQQASISLIQRRLRVG
HHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTRAARLIDELEEFGVIGGHEGSKPRRILMTEEDIKNILEQL
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]