Click here to switch to the map view.

The map label for this gene is spoVD [H]

Identifier: 188585924

GI number: 188585924

Start: 1368639

End: 1370753

Strand: Direct

Name: spoVD [H]

Synonym: Nther_1298

Alternate gene names: 188585924

Gene position: 1368639-1370753 (Clockwise)

Preceding gene: 188585923

Following gene: 188585925

Centisome position: 43.24

GC content: 40.99

Gene sequence:

>2115_bases
GTGGCAAAGAAGCGCCAACATCTCCTACCGACTAAAAGGAGACTTGTACTTATATTTTTCTTTGTACTATTAATTACGAT
CTCATTAATTAGTAGATTAGGATATATACAGCTGGTTATGGGGGAAGAATTACATGAAAAGGCTTGGGAGCAATGGAACA
GAAGTATCCCCACAGGTTCACCTCGAGGAGAAATATTAGATCGGAATGGAGAATTACTAGTCGGTAGTGTAACGGCAGAT
AGTCTGATTGCTATTCCTCAACAAATAGAAAACCCCCAGTTACTTTCGGAGAGGTTAGCGGCTATTCTAGATAGGGATCA
GGAAGAACTTTTTGAAAAGCTGACAGAAGATACGGAACAGGTTATTGTCGAGCGGATATTAGATAAAGAAGACTCTAGGA
AAGTTAAGGCCCTAGGTGACCCAGGTCTTAAAACTACTAGTGAAACCGAACGATATTATCCCCATGGGCGCCTAGCCTCA
CAAGTATTGGGGTTTGTTGGTGTAGATCAAGGTTGGGCGGGAATTGAATACCAATACGATGAGGAACTTAAGGGTCAAGA
AGGATGGCTGATTTTTCAAGCGGATGCAAGACAACAAGAATTACCACATGGAGTCCAACAATTTGTTCCACCTAAAGACG
GTCAGAAATTGCAAACTACTTTAGATAGTCGGATTCAATATATTATGGAACGCGAGCTAGAACGGGCTATGGTGGAATAC
AAACCAGAAGGAGCCATGGCAGTGGCTATGGAACCAAATACTGGTGAAATACTGGGAATGGCCAGTAAACCAGATTACTA
CCCTGGTGAATACAAAGATTTTGATGAATCATTACGAAGGATAACTCCAATCAATAATACTTTTGAACCTGGATCAACTT
TTAAACTAGTAACTCTTTCAGCAGCAATAGAGGAAGGGAAATATAATCCCGATGAAGCTTTTTATTGTCCCGGACATATT
GAAGTCTCTGGTGCAGAAATTGGATGTTGGACTGGTGATGGTCATGGTGCTATAGATTTTACAGAAGTTGTATATGGTTC
TTGTAACCCTGGATTTGTTACATTGGGTCAGCGTTTAGGAACTGAAACGTTATTTGATTATATTCAAGGGTACGGATTTG
GATCTCGAACAGGTATTGACCTGCCGGGAGAAACGTTGGGATTGTTATTTGGACCTGATCAAGTTGGTCCAGTTGAATTA
GCAACAACTTCTTTCGGTCAGGGGATTTCAGTCACTCCTATACAGCAAGTTGTAGCAGTAAGTGCCATTGCCAACGGTGG
TTATATTAATGAACCAAGAATTGCAGATAAATTTTTAGATGAAGAAGGAAATGTAGTTAAAGACAAAGAAGTTAATACCG
TTCGTCGCGCCATCTCTGAAAAAACTTCTCAAGAAGTATCAGAAATTATGAGGGGAGTAGTAAATGAGGGAAGTGGCCAA
AATGCAGCTATTGATGGTTATGAAATTGCTGGCAAAACGGGGACAGCGGAAAAGGTAGGTCCAGAAGGTGGGTATGTCCC
TGGAGAACTAATAGTATCCTTTGTGGGATTTGCACCGGCTGATGATCCTGAAATTCTAATTTATGTAGCTGTAGATACCC
CTACTGAGGGGCCTGCTTGGGGTAGTCAAGTTGCAGCCCCCGTATTTAGAAATATGATGGTTGATATCTTGGACTATTTA
GAAGTGCCTCCTTCTAAACCAGGGGAAATTGAAGAAGAGGTAAATTATGTAGAAGTCCCTAATCTTCTAAATATGGAATT
TGAAGAGGCTGAGGAACATATAGATCAAACTGCCTTAGAGGTTGAATTAATAGGCGATGGTGAAACTATCACAGATCAGA
TCCCTGAACCCGGAGAACAAGTTCCTGAACAATCTTCATTAATTTTATATTTGGAAGCTACAGAAGACAGGGAGGAAGAG
ACAGTAACGGTACCTGATTTAAGGGGAAGAAGCATGCGAGAAACGGGAGAAGTTTTAAATATGATGGGTTTAGAATTGAG
AGAAGAAGGCAGTGGTATTGCTGTTACACAAAATCCGGAAAAGGGGACGAAAGTAGATAAAGGTACATCCGTAACTGTCC
AGTTCGAACCTCCCGATGAATTCAATGAAGAGTAA

Upstream 100 bases:

>100_bases
AAATTGTGGAATTAAAATCTCATCAGAGAATAGAGCAATACGCCAAAGAAGAGTTAGAAATGAAGCGACCCGAATCTAAA
TAAGTTGGGAGTGGTGAGGA

Downstream 100 bases:

>100_bases
GACATTAAATAACCTTCATAGATTAACAAGGTTAAACTATGAATCAAAAACAGAAATTAATAACAGGGAGAGGAGTGAAA
TTATCAAATTAGCCGATTTA

Product: Peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MAKKRQHLLPTKRRLVLIFFFVLLITISLISRLGYIQLVMGEELHEKAWEQWNRSIPTGSPRGEILDRNGELLVGSVTAD
SLIAIPQQIENPQLLSERLAAILDRDQEELFEKLTEDTEQVIVERILDKEDSRKVKALGDPGLKTTSETERYYPHGRLAS
QVLGFVGVDQGWAGIEYQYDEELKGQEGWLIFQADARQQELPHGVQQFVPPKDGQKLQTTLDSRIQYIMERELERAMVEY
KPEGAMAVAMEPNTGEILGMASKPDYYPGEYKDFDESLRRITPINNTFEPGSTFKLVTLSAAIEEGKYNPDEAFYCPGHI
EVSGAEIGCWTGDGHGAIDFTEVVYGSCNPGFVTLGQRLGTETLFDYIQGYGFGSRTGIDLPGETLGLLFGPDQVGPVEL
ATTSFGQGISVTPIQQVVAVSAIANGGYINEPRIADKFLDEEGNVVKDKEVNTVRRAISEKTSQEVSEIMRGVVNEGSGQ
NAAIDGYEIAGKTGTAEKVGPEGGYVPGELIVSFVGFAPADDPEILIYVAVDTPTEGPAWGSQVAAPVFRNMMVDILDYL
EVPPSKPGEIEEEVNYVEVPNLLNMEFEEAEEHIDQTALEVELIGDGETITDQIPEPGEQVPEQSSLILYLEATEDREEE
TVTVPDLRGRSMRETGEVLNMMGLELREEGSGIAVTQNPEKGTKVDKGTSVTVQFEPPDEFNEE

Sequences:

>Translated_704_residues
MAKKRQHLLPTKRRLVLIFFFVLLITISLISRLGYIQLVMGEELHEKAWEQWNRSIPTGSPRGEILDRNGELLVGSVTAD
SLIAIPQQIENPQLLSERLAAILDRDQEELFEKLTEDTEQVIVERILDKEDSRKVKALGDPGLKTTSETERYYPHGRLAS
QVLGFVGVDQGWAGIEYQYDEELKGQEGWLIFQADARQQELPHGVQQFVPPKDGQKLQTTLDSRIQYIMERELERAMVEY
KPEGAMAVAMEPNTGEILGMASKPDYYPGEYKDFDESLRRITPINNTFEPGSTFKLVTLSAAIEEGKYNPDEAFYCPGHI
EVSGAEIGCWTGDGHGAIDFTEVVYGSCNPGFVTLGQRLGTETLFDYIQGYGFGSRTGIDLPGETLGLLFGPDQVGPVEL
ATTSFGQGISVTPIQQVVAVSAIANGGYINEPRIADKFLDEEGNVVKDKEVNTVRRAISEKTSQEVSEIMRGVVNEGSGQ
NAAIDGYEIAGKTGTAEKVGPEGGYVPGELIVSFVGFAPADDPEILIYVAVDTPTEGPAWGSQVAAPVFRNMMVDILDYL
EVPPSKPGEIEEEVNYVEVPNLLNMEFEEAEEHIDQTALEVELIGDGETITDQIPEPGEQVPEQSSLILYLEATEDREEE
TVTVPDLRGRSMRETGEVLNMMGLELREEGSGIAVTQNPEKGTKVDKGTSVTVQFEPPDEFNEE
>Mature_703_residues
AKKRQHLLPTKRRLVLIFFFVLLITISLISRLGYIQLVMGEELHEKAWEQWNRSIPTGSPRGEILDRNGELLVGSVTADS
LIAIPQQIENPQLLSERLAAILDRDQEELFEKLTEDTEQVIVERILDKEDSRKVKALGDPGLKTTSETERYYPHGRLASQ
VLGFVGVDQGWAGIEYQYDEELKGQEGWLIFQADARQQELPHGVQQFVPPKDGQKLQTTLDSRIQYIMERELERAMVEYK
PEGAMAVAMEPNTGEILGMASKPDYYPGEYKDFDESLRRITPINNTFEPGSTFKLVTLSAAIEEGKYNPDEAFYCPGHIE
VSGAEIGCWTGDGHGAIDFTEVVYGSCNPGFVTLGQRLGTETLFDYIQGYGFGSRTGIDLPGETLGLLFGPDQVGPVELA
TTSFGQGISVTPIQQVVAVSAIANGGYINEPRIADKFLDEEGNVVKDKEVNTVRRAISEKTSQEVSEIMRGVVNEGSGQN
AAIDGYEIAGKTGTAEKVGPEGGYVPGELIVSFVGFAPADDPEILIYVAVDTPTEGPAWGSQVAAPVFRNMMVDILDYLE
VPPSKPGEIEEEVNYVEVPNLLNMEFEEAEEHIDQTALEVELIGDGETITDQIPEPGEQVPEQSSLILYLEATEDREEET
VTVPDLRGRSMRETGEVLNMMGLELREEGSGIAVTQNPEKGTKVDKGTSVTVQFEPPDEFNEE

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=575, Percent_Identity=29.7391304347826, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1786854, Length=619, Percent_Identity=24.0710823909532, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 77696; Mature: 77565

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKRQHLLPTKRRLVLIFFFVLLITISLISRLGYIQLVMGEELHEKAWEQWNRSIPTGS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCCCC
PRGEILDRNGELLVGSVTADSLIAIPQQIENPQLLSERLAAILDRDQEELFEKLTEDTEQ
CCCCEECCCCCEEEEECCCCHHHHCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VIVERILDKEDSRKVKALGDPGLKTTSETERYYPHGRLASQVLGFVGVDQGWAGIEYQYD
HHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECC
EELKGQEGWLIFQADARQQELPHGVQQFVPPKDGQKLQTTLDSRIQYIMERELERAMVEY
HHCCCCCCEEEEECCCCHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
KPEGAMAVAMEPNTGEILGMASKPDYYPGEYKDFDESLRRITPINNTFEPGSTFKLVTLS
CCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEE
AAIEEGKYNPDEAFYCPGHIEVSGAEIGCWTGDGHGAIDFTEVVYGSCNPGFVTLGQRLG
EHHHCCCCCCCCCEECCCEEEECCCEEEEEECCCCCCEEHHHHHCCCCCCCHHHHHHHHC
TETLFDYIQGYGFGSRTGIDLPGETLGLLFGPDQVGPVELATTSFGQGISVTPIQQVVAV
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHH
SAIANGGYINEPRIADKFLDEEGNVVKDKEVNTVRRAISEKTSQEVSEIMRGVVNEGSGQ
HHHHCCCCCCCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NAAIDGYEIAGKTGTAEKVGPEGGYVPGELIVSFVGFAPADDPEILIYVAVDTPTEGPAW
CCEECCEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCC
GSQVAAPVFRNMMVDILDYLEVPPSKPGEIEEEVNYVEVPNLLNMEFEEAEEHIDQTALE
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEECCCHHCCCHHHHHHHHHHHEEE
VELIGDGETITDQIPEPGEQVPEQSSLILYLEATEDREEETVTVPDLRGRSMRETGEVLN
EEEECCCCCHHCCCCCCHHHCCCCCCEEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHH
MMGLELREEGSGIAVTQNPEKGTKVDKGTSVTVQFEPPDEFNEE
HHCCHHHCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
AKKRQHLLPTKRRLVLIFFFVLLITISLISRLGYIQLVMGEELHEKAWEQWNRSIPTGS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCCCC
PRGEILDRNGELLVGSVTADSLIAIPQQIENPQLLSERLAAILDRDQEELFEKLTEDTEQ
CCCCEECCCCCEEEEECCCCHHHHCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VIVERILDKEDSRKVKALGDPGLKTTSETERYYPHGRLASQVLGFVGVDQGWAGIEYQYD
HHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECC
EELKGQEGWLIFQADARQQELPHGVQQFVPPKDGQKLQTTLDSRIQYIMERELERAMVEY
HHCCCCCCEEEEECCCCHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
KPEGAMAVAMEPNTGEILGMASKPDYYPGEYKDFDESLRRITPINNTFEPGSTFKLVTLS
CCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEE
AAIEEGKYNPDEAFYCPGHIEVSGAEIGCWTGDGHGAIDFTEVVYGSCNPGFVTLGQRLG
EHHHCCCCCCCCCEECCCEEEECCCEEEEEECCCCCCEEHHHHHCCCCCCCHHHHHHHHC
TETLFDYIQGYGFGSRTGIDLPGETLGLLFGPDQVGPVELATTSFGQGISVTPIQQVVAV
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHH
SAIANGGYINEPRIADKFLDEEGNVVKDKEVNTVRRAISEKTSQEVSEIMRGVVNEGSGQ
HHHHCCCCCCCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NAAIDGYEIAGKTGTAEKVGPEGGYVPGELIVSFVGFAPADDPEILIYVAVDTPTEGPAW
CCEECCEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCC
GSQVAAPVFRNMMVDILDYLEVPPSKPGEIEEEVNYVEVPNLLNMEFEEAEEHIDQTALE
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEECCCHHCCCHHHHHHHHHHHEEE
VELIGDGETITDQIPEPGEQVPEQSSLILYLEATEDREEETVTVPDLRGRSMRETGEVLN
EEEECCCCCHHCCCCCCHHHCCCCCCEEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHH
MMGLELREEGSGIAVTQNPEKGTKVDKGTSVTVQFEPPDEFNEE
HHCCHHHCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]