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The map label for this gene is ycbL [C]

Identifier: 188585916

GI number: 188585916

Start: 1361704

End: 1362324

Strand: Direct

Name: ycbL [C]

Synonym: Nther_1290

Alternate gene names: 188585916

Gene position: 1361704-1362324 (Clockwise)

Preceding gene: 188585915

Following gene: 188585917

Centisome position: 43.02

GC content: 37.36

Gene sequence:

>621_bases
TTGATTATTGAGCAATTAGTTGTAGGTGAATTAGGTGCTAACTGTTATATTGTCGGTTGTCAGGAAACCGGTGAAGCAGT
GATTATTGATCCAGGCGGGAATGGTGAAAAAATCCACCAACAAATCAAAGAGTTAGATATGACTCCCTCTATGATAATTA
ACACTCATGGTCATGTCGATCATATTGGGGCTAATTCATATTTAAAAGAACACACTGATGCCGAATTGGGGATTCATCCC
AAAGATGCTCCAATGCTAACTGACCCCAAACTTAATTTGTCCATGTTCACTGGAAAAGAGATTATTAGTCCGTCAGCAGA
TATACATTTAAATGACGGTGATTCTATAAAAGTAGGAAATTTAAAAGGAGAAATAATCAATACTCCAGGTCATACTCCAG
GAGGAATATGTATTAAAATTGATAATAATCTGTTCTCTGGTGACACCCTATTTACTGAAGGGATAGGCCGTTGTGATTTA
CCGGGTGGAAACCAAGATGAATTACTTAAATCCATAAGAGAACAGCTGTTCACACTTTCCGATGATCTTGTTGTATATCC
AGGGCACGGAGGAAGCACTACCATTGCTCATGAGAAAAGAAAAAATCCTTTTCTTAAATAA

Upstream 100 bases:

>100_bases
AGAACATATGGAAGTAGATATTTTAAATGACGGTCCTGTGACTATTTTATTAGATAGTAACAAAAAGTTTTGATTACAGA
TAGAAGGAGGCGATAAAACA

Downstream 100 bases:

>100_bases
TATAACCTTTGACAACGGGATAGCGATATTATAAAATAATTTAGAAATAAAATATTGTAAAAATGCTATGATGGGAAGAG
TAGAAAAGATACCTTTTTAA

Product: beta-lactamase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIIEQLVVGELGANCYIVGCQETGEAVIIDPGGNGEKIHQQIKELDMTPSMIINTHGHVDHIGANSYLKEHTDAELGIHP
KDAPMLTDPKLNLSMFTGKEIISPSADIHLNDGDSIKVGNLKGEIINTPGHTPGGICIKIDNNLFSGDTLFTEGIGRCDL
PGGNQDELLKSIREQLFTLSDDLVVYPGHGGSTTIAHEKRKNPFLK

Sequences:

>Translated_206_residues
MIIEQLVVGELGANCYIVGCQETGEAVIIDPGGNGEKIHQQIKELDMTPSMIINTHGHVDHIGANSYLKEHTDAELGIHP
KDAPMLTDPKLNLSMFTGKEIISPSADIHLNDGDSIKVGNLKGEIINTPGHTPGGICIKIDNNLFSGDTLFTEGIGRCDL
PGGNQDELLKSIREQLFTLSDDLVVYPGHGGSTTIAHEKRKNPFLK
>Mature_206_residues
MIIEQLVVGELGANCYIVGCQETGEAVIIDPGGNGEKIHQQIKELDMTPSMIINTHGHVDHIGANSYLKEHTDAELGIHP
KDAPMLTDPKLNLSMFTGKEIISPSADIHLNDGDSIKVGNLKGEIINTPGHTPGGICIKIDNNLFSGDTLFTEGIGRCDL
PGGNQDELLKSIREQLFTLSDDLVVYPGHGGSTTIAHEKRKNPFLK

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=197, Percent_Identity=32.994923857868, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI21703352, Length=173, Percent_Identity=31.7919075144509, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI116642887, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=202, Percent_Identity=37.1287128712871, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17538952, Length=212, Percent_Identity=35.377358490566, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221330176, Length=212, Percent_Identity=31.1320754716981, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356335, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667703, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667711, Length=181, Percent_Identity=27.0718232044199, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 22214; Mature: 22214

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIEQLVVGELGANCYIVGCQETGEAVIIDPGGNGEKIHQQIKELDMTPSMIINTHGHVD
CCHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
HIGANSYLKEHTDAELGIHPKDAPMLTDPKLNLSMFTGKEIISPSADIHLNDGDSIKVGN
ECCCCHHHHHCCCCCCCCCCCCCCEEECCCCCEEEECCCHHCCCCCCEEECCCCEEEECC
LKGEIINTPGHTPGGICIKIDNNLFSGDTLFTEGIGRCDLPGGNQDELLKSIREQLFTLS
CCCEEEECCCCCCCEEEEEECCCEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
DDLVVYPGHGGSTTIAHEKRKNPFLK
CCEEEECCCCCCCCEECHHCCCCCCC
>Mature Secondary Structure
MIIEQLVVGELGANCYIVGCQETGEAVIIDPGGNGEKIHQQIKELDMTPSMIINTHGHVD
CCHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
HIGANSYLKEHTDAELGIHPKDAPMLTDPKLNLSMFTGKEIISPSADIHLNDGDSIKVGN
ECCCCHHHHHCCCCCCCCCCCCCCEEECCCCCEEEECCCHHCCCCCCEEECCCCEEEECC
LKGEIINTPGHTPGGICIKIDNNLFSGDTLFTEGIGRCDLPGGNQDELLKSIREQLFTLS
CCCEEEECCCCCCCEEEEEECCCEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
DDLVVYPGHGGSTTIAHEKRKNPFLK
CCEEEECCCCCCCCEECHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]