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The map label for this gene is ccdA [H]

Identifier: 188585888

GI number: 188585888

Start: 1334191

End: 1334898

Strand: Direct

Name: ccdA [H]

Synonym: Nther_1262

Alternate gene names: 188585888

Gene position: 1334191-1334898 (Clockwise)

Preceding gene: 188585887

Following gene: 188585889

Centisome position: 42.15

GC content: 34.89

Gene sequence:

>708_bases
ATGATAGAGACCGTATCAATTTCTATAGCCTTTGCAGCCGGATTATTATTTTTCTTTAGTCCATGCGTATGGCCTATGTA
TCCGGCTTATATATCATATATTGCGGGTTCTTCAATTGGAGACGTAAAAGACGGGTTAAATAAAACGAAAGTTATGGTAA
ATGCACTGGGCTTTGTAGCTGGATTTACTTTGGTGTTTGTTCTGCTTGGGGCAACGGCTACGGGGATAGGTGAATTTTTA
GATGAACGACAGAACTATTTTCGAGTTGGTGCTGGTATTTTAATCATCTTATTCGGGCTACAATTGGGTGGTTTTTATAG
ATTACCCTTTCTTAATAAAGAAAAAAAGATCAATTTTATACCACAAAACCCAGGCTTTTTTTCATCGGCTGTTTTTGGAA
CAACTTTTGCTTTTGCATGGAGTCCTTGTACTACTGCTATTTTATTTTCAATACTCTTATACGCAAGTCAATCAGATACG
GTTTATCAGGGAATGGTATTACTAGCGATCTTTTCCATGGGTTTTTCCATTCCATTCTTATTACTTGCTTATTTTATGCG
ATTACTTCATCCACGCTTGAGCAAGTTTAGTAAATATTTGCCTTTGTTAAATAAAATTGGCGGTAGCTTATTAATAGTTA
TTGGATTTTTAGTCCTTTTTGATAAGTTTGCAGATATTAGTTTATGGCTGTTTAACTTGGTTAATTAA

Upstream 100 bases:

>100_bases
AATTAAAAAATACTATTCTAAAAAACATTAAGGTTAAAATACTCCTAGATTGATTATGGCGAAAAAATCAACAAGTATAG
AAGGGAGAGGAGTATTACTC

Downstream 100 bases:

>100_bases
AGGGGGGAGTATCAAAATGTTCTTAAAAAAATCATTATTGATAATTCTGCTATTAGTTCTGATGACTGGCTCTTTCCTTT
TGTCGGGATGTAATCCAGAT

Product: cytochrome c biogenesis protein transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIETVSISIAFAAGLLFFFSPCVWPMYPAYISYIAGSSIGDVKDGLNKTKVMVNALGFVAGFTLVFVLLGATATGIGEFL
DERQNYFRVGAGILIILFGLQLGGFYRLPFLNKEKKINFIPQNPGFFSSAVFGTTFAFAWSPCTTAILFSILLYASQSDT
VYQGMVLLAIFSMGFSIPFLLLAYFMRLLHPRLSKFSKYLPLLNKIGGSLLIVIGFLVLFDKFADISLWLFNLVN

Sequences:

>Translated_235_residues
MIETVSISIAFAAGLLFFFSPCVWPMYPAYISYIAGSSIGDVKDGLNKTKVMVNALGFVAGFTLVFVLLGATATGIGEFL
DERQNYFRVGAGILIILFGLQLGGFYRLPFLNKEKKINFIPQNPGFFSSAVFGTTFAFAWSPCTTAILFSILLYASQSDT
VYQGMVLLAIFSMGFSIPFLLLAYFMRLLHPRLSKFSKYLPLLNKIGGSLLIVIGFLVLFDKFADISLWLFNLVN
>Mature_235_residues
MIETVSISIAFAAGLLFFFSPCVWPMYPAYISYIAGSSIGDVKDGLNKTKVMVNALGFVAGFTLVFVLLGATATGIGEFL
DERQNYFRVGAGILIILFGLQLGGFYRLPFLNKEKKINFIPQNPGFFSSAVFGTTFAFAWSPCTTAILFSILLYASQSDT
VYQGMVLLAIFSMGFSIPFLLLAYFMRLLHPRLSKFSKYLPLLNKIGGSLLIVIGFLVLFDKFADISLWLFNLVN

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=185, Percent_Identity=29.1891891891892, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 25972; Mature: 25972

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETVSISIAFAAGLLFFFSPCVWPMYPAYISYIAGSSIGDVKDGLNKTKVMVNALGFVA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHH
GFTLVFVLLGATATGIGEFLDERQNYFRVGAGILIILFGLQLGGFYRLPFLNKEKKINFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEC
PQNPGFFSSAVFGTTFAFAWSPCTTAILFSILLYASQSDTVYQGMVLLAIFSMGFSIPFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHH
LLAYFMRLLHPRLSKFSKYLPLLNKIGGSLLIVIGFLVLFDKFADISLWLFNLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIETVSISIAFAAGLLFFFSPCVWPMYPAYISYIAGSSIGDVKDGLNKTKVMVNALGFVA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHH
GFTLVFVLLGATATGIGEFLDERQNYFRVGAGILIILFGLQLGGFYRLPFLNKEKKINFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEC
PQNPGFFSSAVFGTTFAFAWSPCTTAILFSILLYASQSDTVYQGMVLLAIFSMGFSIPFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHH
LLAYFMRLLHPRLSKFSKYLPLLNKIGGSLLIVIGFLVLFDKFADISLWLFNLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]