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The map label for this gene is murB [H]

Identifier: 188585619

GI number: 188585619

Start: 1056563

End: 1057465

Strand: Direct

Name: murB [H]

Synonym: Nther_0992

Alternate gene names: 188585619

Gene position: 1056563-1057465 (Clockwise)

Preceding gene: 188585618

Following gene: 188585623

Centisome position: 33.38

GC content: 37.98

Gene sequence:

>903_bases
ATGAACACTCAAGCCATATACGATGAGCTATTGAACCATCTACCTAAAGATAATATTAAACTTCAACACGAATTGGCACC
GTATACAACTTTTAAGATAGGTGGACCAGCTGAGCTTTTTGTGACACCATCCAATATTGAAGAAGTTCAAGCTGTTTTAA
ACTTGGTAAATCAAGAAGAACTCCCTTATTTTGTGCTTGGCAATGCCTCTAATGTTTTAATTGACGACAATGGTTTATCG
GGAATAGTAATTTATCTTGGAGAAACCTTTAAAGACATACAAGTAGAGGGGACAGAAATAACAGCTCAGAGTGGAGTTTC
TCTTAACAAGCTTAGTCGTATGGCTCTTAAACATGGTTTGACTGGTCTAGAGTTCGCAGAAGGCATTCCTGGAACCTTAG
GTGGTGGTTTATACATGAATGCCGGAGCCTTTGGCGGGCAACTCAGTAATGTGGTTAAACAAGTGACTGCTATAGTGGAC
CACCAAATTCAAAACTATACACGAGAGTCTATGGACTTTGGATATCGCAGTAGTACTTTTCAAAATCAGAATGCAATAAT
ACTTCAGGCAACACTTGCCTTACAAAAGGGTGACTTTGACCAAATTAAGTCTTATATGGAAGACCTGAAATCCAGGCGAA
CTGAAAAGCAGCCTTTAAATTATCCATCAGCAGGTTCCGTTTTTAAAAGGCCTGAAGGATACTATGCAGGTAAACTGATT
GAAGATAGTGGCTTGAAAGGTGTTGAAATAGGAGGAGCCAAGGTTTCTGAAAAACATTGTGGTTTTATAATAAACACCGG
TACGGCAACGAGTCGTGATGTTAAAGAACTTGTATCATATATCCAAAAAACAGTTAAAGAAAAGTTTGGTGTCACTCTAG
AAAGAGAATTAAAATATCTTTAA

Upstream 100 bases:

>100_bases
AAATAATTTGTTGCAATAAAAAAGATCGTAGTGTACTATGTTGAATATGCTGATATGGAAGGAAAGTATTTTAACTATTG
ATTACAGAGGTGATTCGCTC

Downstream 100 bases:

>100_bases
ATCTTTAGTATTAGTATCTTTAAGACTATGGTTTTTGATTCATCGTTGAGTTTGGTTTATCGTTGAGAATGATTATTATA
GGCTTTAATTATCAGTGATT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNTQAIYDELLNHLPKDNIKLQHELAPYTTFKIGGPAELFVTPSNIEEVQAVLNLVNQEELPYFVLGNASNVLIDDNGLS
GIVIYLGETFKDIQVEGTEITAQSGVSLNKLSRMALKHGLTGLEFAEGIPGTLGGGLYMNAGAFGGQLSNVVKQVTAIVD
HQIQNYTRESMDFGYRSSTFQNQNAIILQATLALQKGDFDQIKSYMEDLKSRRTEKQPLNYPSAGSVFKRPEGYYAGKLI
EDSGLKGVEIGGAKVSEKHCGFIINTGTATSRDVKELVSYIQKTVKEKFGVTLERELKYL

Sequences:

>Translated_300_residues
MNTQAIYDELLNHLPKDNIKLQHELAPYTTFKIGGPAELFVTPSNIEEVQAVLNLVNQEELPYFVLGNASNVLIDDNGLS
GIVIYLGETFKDIQVEGTEITAQSGVSLNKLSRMALKHGLTGLEFAEGIPGTLGGGLYMNAGAFGGQLSNVVKQVTAIVD
HQIQNYTRESMDFGYRSSTFQNQNAIILQATLALQKGDFDQIKSYMEDLKSRRTEKQPLNYPSAGSVFKRPEGYYAGKLI
EDSGLKGVEIGGAKVSEKHCGFIINTGTATSRDVKELVSYIQKTVKEKFGVTLERELKYL
>Mature_300_residues
MNTQAIYDELLNHLPKDNIKLQHELAPYTTFKIGGPAELFVTPSNIEEVQAVLNLVNQEELPYFVLGNASNVLIDDNGLS
GIVIYLGETFKDIQVEGTEITAQSGVSLNKLSRMALKHGLTGLEFAEGIPGTLGGGLYMNAGAFGGQLSNVVKQVTAIVD
HQIQNYTRESMDFGYRSSTFQNQNAIILQATLALQKGDFDQIKSYMEDLKSRRTEKQPLNYPSAGSVFKRPEGYYAGKLI
EDSGLKGVEIGGAKVSEKHCGFIINTGTATSRDVKELVSYIQKTVKEKFGVTLERELKYL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32981; Mature: 32981

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQAIYDELLNHLPKDNIKLQHELAPYTTFKIGGPAELFVTPSNIEEVQAVLNLVNQEE
CCHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCC
LPYFVLGNASNVLIDDNGLSGIVIYLGETFKDIQVEGTEITAQSGVSLNKLSRMALKHGL
CCEEEECCCCEEEEECCCCCEEEEEECCCCCCEEECCCEEECCCCCCHHHHHHHHHHHCC
TGLEFAEGIPGTLGGGLYMNAGAFGGQLSNVVKQVTAIVDHQIQNYTRESMDFGYRSSTF
CCCHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QNQNAIILQATLALQKGDFDQIKSYMEDLKSRRTEKQPLNYPSAGSVFKRPEGYYAGKLI
CCCCEEEEEEEEHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECEEE
EDSGLKGVEIGGAKVSEKHCGFIINTGTATSRDVKELVSYIQKTVKEKFGVTLERELKYL
CCCCCCEEEECCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MNTQAIYDELLNHLPKDNIKLQHELAPYTTFKIGGPAELFVTPSNIEEVQAVLNLVNQEE
CCHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCC
LPYFVLGNASNVLIDDNGLSGIVIYLGETFKDIQVEGTEITAQSGVSLNKLSRMALKHGL
CCEEEECCCCEEEEECCCCCEEEEEECCCCCCEEECCCEEECCCCCCHHHHHHHHHHHCC
TGLEFAEGIPGTLGGGLYMNAGAFGGQLSNVVKQVTAIVDHQIQNYTRESMDFGYRSSTF
CCCHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QNQNAIILQATLALQKGDFDQIKSYMEDLKSRRTEKQPLNYPSAGSVFKRPEGYYAGKLI
CCCCEEEEEEEEHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECEEE
EDSGLKGVEIGGAKVSEKHCGFIINTGTATSRDVKELVSYIQKTVKEKFGVTLERELKYL
CCCCCCEEEECCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA