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The map label for this gene is resE [H]

Identifier: 188585612

GI number: 188585612

Start: 1048303

End: 1050096

Strand: Direct

Name: resE [H]

Synonym: Nther_0985

Alternate gene names: 188585612

Gene position: 1048303-1050096 (Clockwise)

Preceding gene: 188585611

Following gene: 188585616

Centisome position: 33.12

GC content: 32.61

Gene sequence:

>1794_bases
ATGAGAACAATTAAAAGTAAAATTAATACAGCTTTTTCCATATTAATTGCCCTTGCTTTCATAAGCATGGGATTATATTT
ATTTAATTATTTTTCAAATTTTTATTTAGAAAATTTGGAAGATCAGCTAGTTAATAAAGCAAAAATGATATCACACAGCA
TTAAAGATAGTGAACTCGCAGGCGATGCATTGCAAGAATACGTTGTCACTTTAGGCACAGATACTGGTTTTAGATTTACA
GTAGTCAATAATGATGGAACTGTCCTTGCCGAGTCTGAAAAGAATCCGGAAGTAATGGATAATCATCTAGATCGTCCGGA
AATAAAAAAAGCTTATGAAGAAGGAACAGGTCTTCATACCAGATATTCAAATACAATTGACGAAGATTTGCTATACGCTG
CAGTCCCTATTTACAATGAGGAAATAGGAAATCAAGACAATAAAAATAGGGATGATTTAATTGTCAATGGTTTTGCCCGA
GTTGCTTTTCCCTTAACGGAAATTCAAAGTGTCAGGAATCATTTAGGAGTAATTATTGGGTCTGGTACCTTATTGGCATT
ATTATTTACCTGGTTATTCGGCTCATTGATTGCCCAGTCTATTACTTATCCTTTGGAAGTTTTAAGTAAATGGACTGGGC
AAGTTTCAAAAGGTGATTTTAGTGAAGATAAGCCAATAAACTCAAAAGATGAAATCGGGGAATTATCTCATAGATTTCAT
CAAATGAAAAATAATTTATCAACAATTATGAGCCAATTGACGGAAGAAAAAAATAGATTATCAACACTATTAAATAATAT
GCCCGATGGTGTTATCGAAATCAACCATAAAAGTGAAGTGACTCTTATAAATCCAGCTGCCAGGAGTTTTTTAAACATTA
ATGCTTACGATTCCGTTGATCAACAAGAATTAGTATCATTAACTAGAAATTTTGATTTGAATAATGCTGTAACTCAGGTT
CTTAAATCAGGGGAACAGGTTTCTAGAGAAACTGATTTTAACAATCAGATTGTTAGAATGTATGTTACTCCTCTACCTCT
TTTTGAAGAAGGATCTAGAGGAGCTGTTGTGATACTTCAGGATATTACTGATTTAACTAAACTGGAACAGATGAGAAAAG
AATTTATTTCGAATATTAGTCACGAATTGAAAACACCTTTAACATCGATAAAAGGCTTTGTAGAAACTCTAAAGGAAGAA
ACTTTAGGTGAAAATAACACTCAACGGGAGTTTTTAAATATTATTGAAGAAGAGACGGATAGAGTTAGTAGACTGATTAA
TGATTTAACTATACTTTCTAGGCTGGAAACTAATAAAGTTGAATTTAACCAAGATGAAGTTAATGTGCTAAACTTTTTAG
ATAAAACCGTATCTATATCACAAAAAAGATGGCAGCAAGATGGATATCGGATATATAGAGGCGGAGTTCCTTTTGATTTA
AAAGCTTTAATGGATGAGGATAAAATTCAGCAAGTTATTTTAAATTTGGTTGACAATGCGTGTCGTCATAATCCTCCGGG
AACAAAAATCAAGCTAAAAGCAGTTTCTGAGAAGGATTATATAAGATTTTCTGTAACAGATAATGGTAAAGGGATCCCGG
AAGAAGATAAAGAGAGAATTTTTGAAAGGTTTTATCGAGTTGATAAATCCAGGTATAGAGATTATGGAGGTACTGGTCTC
GGGTTATCGATAGCAAAACATGCAGTTATTGGTCATAATTCAAGTTTAAATGTAATAAGTAGGGTCGGCCGTGGGACAAC
ATTTTATTTTTATGTTAAAAGAATCCTTGATTAA

Upstream 100 bases:

>100_bases
GACATCTACGCCAGAAAATTAGTGAAGCGGGTGGTCCTCCTGACTTAGTAGAGACAGTCAGGGGCATAGGATATCGTTTA
AAAGAAATGGAGTAATTGTT

Downstream 100 bases:

>100_bases
AAGAAATCCCCTTCTTAGGTGTTAATTAAACCCAGAAGGGGATTTCTTTTAATCAAGCCCAAAAACTATTTATTCGTCGT
CATGTTCGCATTCATGTTCT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MRTIKSKINTAFSILIALAFISMGLYLFNYFSNFYLENLEDQLVNKAKMISHSIKDSELAGDALQEYVVTLGTDTGFRFT
VVNNDGTVLAESEKNPEVMDNHLDRPEIKKAYEEGTGLHTRYSNTIDEDLLYAAVPIYNEEIGNQDNKNRDDLIVNGFAR
VAFPLTEIQSVRNHLGVIIGSGTLLALLFTWLFGSLIAQSITYPLEVLSKWTGQVSKGDFSEDKPINSKDEIGELSHRFH
QMKNNLSTIMSQLTEEKNRLSTLLNNMPDGVIEINHKSEVTLINPAARSFLNINAYDSVDQQELVSLTRNFDLNNAVTQV
LKSGEQVSRETDFNNQIVRMYVTPLPLFEEGSRGAVVILQDITDLTKLEQMRKEFISNISHELKTPLTSIKGFVETLKEE
TLGENNTQREFLNIIEEETDRVSRLINDLTILSRLETNKVEFNQDEVNVLNFLDKTVSISQKRWQQDGYRIYRGGVPFDL
KALMDEDKIQQVILNLVDNACRHNPPGTKIKLKAVSEKDYIRFSVTDNGKGIPEEDKERIFERFYRVDKSRYRDYGGTGL
GLSIAKHAVIGHNSSLNVISRVGRGTTFYFYVKRILD

Sequences:

>Translated_597_residues
MRTIKSKINTAFSILIALAFISMGLYLFNYFSNFYLENLEDQLVNKAKMISHSIKDSELAGDALQEYVVTLGTDTGFRFT
VVNNDGTVLAESEKNPEVMDNHLDRPEIKKAYEEGTGLHTRYSNTIDEDLLYAAVPIYNEEIGNQDNKNRDDLIVNGFAR
VAFPLTEIQSVRNHLGVIIGSGTLLALLFTWLFGSLIAQSITYPLEVLSKWTGQVSKGDFSEDKPINSKDEIGELSHRFH
QMKNNLSTIMSQLTEEKNRLSTLLNNMPDGVIEINHKSEVTLINPAARSFLNINAYDSVDQQELVSLTRNFDLNNAVTQV
LKSGEQVSRETDFNNQIVRMYVTPLPLFEEGSRGAVVILQDITDLTKLEQMRKEFISNISHELKTPLTSIKGFVETLKEE
TLGENNTQREFLNIIEEETDRVSRLINDLTILSRLETNKVEFNQDEVNVLNFLDKTVSISQKRWQQDGYRIYRGGVPFDL
KALMDEDKIQQVILNLVDNACRHNPPGTKIKLKAVSEKDYIRFSVTDNGKGIPEEDKERIFERFYRVDKSRYRDYGGTGL
GLSIAKHAVIGHNSSLNVISRVGRGTTFYFYVKRILD
>Mature_597_residues
MRTIKSKINTAFSILIALAFISMGLYLFNYFSNFYLENLEDQLVNKAKMISHSIKDSELAGDALQEYVVTLGTDTGFRFT
VVNNDGTVLAESEKNPEVMDNHLDRPEIKKAYEEGTGLHTRYSNTIDEDLLYAAVPIYNEEIGNQDNKNRDDLIVNGFAR
VAFPLTEIQSVRNHLGVIIGSGTLLALLFTWLFGSLIAQSITYPLEVLSKWTGQVSKGDFSEDKPINSKDEIGELSHRFH
QMKNNLSTIMSQLTEEKNRLSTLLNNMPDGVIEINHKSEVTLINPAARSFLNINAYDSVDQQELVSLTRNFDLNNAVTQV
LKSGEQVSRETDFNNQIVRMYVTPLPLFEEGSRGAVVILQDITDLTKLEQMRKEFISNISHELKTPLTSIKGFVETLKEE
TLGENNTQREFLNIIEEETDRVSRLINDLTILSRLETNKVEFNQDEVNVLNFLDKTVSISQKRWQQDGYRIYRGGVPFDL
KALMDEDKIQQVILNLVDNACRHNPPGTKIKLKAVSEKDYIRFSVTDNGKGIPEEDKERIFERFYRVDKSRYRDYGGTGL
GLSIAKHAVIGHNSSLNVISRVGRGTTFYFYVKRILD

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=375, Percent_Identity=31.7333333333333, Blast_Score=168, Evalue=9e-43,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=33.7662337662338, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788393, Length=217, Percent_Identity=28.110599078341, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=386, Percent_Identity=25.3886010362694, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=25.5936675461741, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790346, Length=213, Percent_Identity=31.4553990610329, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=27.6497695852535, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=27.0916334661355, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=28.3185840707965, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=24.8868778280543, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=27.5109170305677, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=258, Percent_Identity=27.1317829457364, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=28.1938325991189, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=223, Percent_Identity=24.2152466367713, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=26.2931034482759, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=242, Percent_Identity=25.2066115702479, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789403, Length=212, Percent_Identity=28.7735849056604, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67888; Mature: 67888

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIKSKINTAFSILIALAFISMGLYLFNYFSNFYLENLEDQLVNKAKMISHSIKDSELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GDALQEYVVTLGTDTGFRFTVVNNDGTVLAESEKNPEVMDNHLDRPEIKKAYEEGTGLHT
HHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCHHHHHCCCCHHHHHHHHHCCCCCC
RYSNTIDEDLLYAAVPIYNEEIGNQDNKNRDDLIVNGFARVAFPLTEIQSVRNHLGVIIG
CCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCEEEC
SGTLLALLFTWLFGSLIAQSITYPLEVLSKWTGQVSKGDFSEDKPINSKDEIGELSHRFH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QMKNNLSTIMSQLTEEKNRLSTLLNNMPDGVIEINHKSEVTLINPAARSFLNINAYDSVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECHHHHHHEECCCCCCCC
QQELVSLTRNFDLNNAVTQVLKSGEQVSRETDFNNQIVRMYVTPLPLFEEGSRGAVVILQ
HHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEH
DITDLTKLEQMRKEFISNISHELKTPLTSIKGFVETLKEETLGENNTQREFLNIIEEETD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RVSRLINDLTILSRLETNKVEFNQDEVNVLNFLDKTVSISQKRWQQDGYRIYRGGVPFDL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
KALMDEDKIQQVILNLVDNACRHNPPGTKIKLKAVSEKDYIRFSVTDNGKGIPEEDKERI
HHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHH
FERFYRVDKSRYRDYGGTGLGLSIAKHAVIGHNSSLNVISRVGRGTTFYFYVKRILD
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHC
>Mature Secondary Structure
MRTIKSKINTAFSILIALAFISMGLYLFNYFSNFYLENLEDQLVNKAKMISHSIKDSELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GDALQEYVVTLGTDTGFRFTVVNNDGTVLAESEKNPEVMDNHLDRPEIKKAYEEGTGLHT
HHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCHHHHHCCCCHHHHHHHHHCCCCCC
RYSNTIDEDLLYAAVPIYNEEIGNQDNKNRDDLIVNGFARVAFPLTEIQSVRNHLGVIIG
CCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCEEEC
SGTLLALLFTWLFGSLIAQSITYPLEVLSKWTGQVSKGDFSEDKPINSKDEIGELSHRFH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QMKNNLSTIMSQLTEEKNRLSTLLNNMPDGVIEINHKSEVTLINPAARSFLNINAYDSVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECHHHHHHEECCCCCCCC
QQELVSLTRNFDLNNAVTQVLKSGEQVSRETDFNNQIVRMYVTPLPLFEEGSRGAVVILQ
HHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEH
DITDLTKLEQMRKEFISNISHELKTPLTSIKGFVETLKEETLGENNTQREFLNIIEEETD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RVSRLINDLTILSRLETNKVEFNQDEVNVLNFLDKTVSISQKRWQQDGYRIYRGGVPFDL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
KALMDEDKIQQVILNLVDNACRHNPPGTKIKLKAVSEKDYIRFSVTDNGKGIPEEDKERI
HHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHH
FERFYRVDKSRYRDYGGTGLGLSIAKHAVIGHNSSLNVISRVGRGTTFYFYVKRILD
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]