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The map label for this gene is arsC1 [H]

Identifier: 188585596

GI number: 188585596

Start: 1030860

End: 1031273

Strand: Direct

Name: arsC1 [H]

Synonym: Nther_0969

Alternate gene names: 188585596

Gene position: 1030860-1031273 (Clockwise)

Preceding gene: 188585593

Following gene: 188585597

Centisome position: 32.56

GC content: 37.68

Gene sequence:

>414_bases
ATGAAGCCAAAAGTAGCTTTTATCTGTGTTCATAATTCATGTCGTTCACAAATGGCTGAAGCTTTGGGTAAGTTGTATGC
ATCCGATGTGTTTGATTCTTATTCGGCGGGGACGGAAACCAAGCCTGAAATTAATCAAGATGCTGTCAAAGTAGTCAAAG
ATTTATATGGTGTAGATATGAATCAAGATCAGTATTCAAAGTTGATATCTGAATTGCCGGATATAGATGTAGTTATTAAG
ATGGGTTGTAATGTTGCTTGCCCATATTTACCTGCAAAACATGAAGAAGACTGGGGACTAGATGATCCTTCTGGTAAATC
CCAAGAGGAATTTGTGAGGACAGCAAGAGAAATTGAAAGAAAAGTTAAAGATCTTGCTCAAAGAATTGAACAGGGGGAGA
TTGAGCTCAATTAG

Upstream 100 bases:

>100_bases
GGTAATCTAAATTAAAATCATTTAATAATTATCAGTTATTGTCAACAGAAAGTGCGGTATCAAAAATAAAATTAGAGTTC
CTTTAACGAGAGGTGTTTTT

Downstream 100 bases:

>100_bases
CTGACAATTTTAGTAGGAATGTAAAATCTTAAAGTAAGTCAAATTCCTCAAAAACTGGCAAAAGGGAAATAAATGTTATA
TTGAAGGAGATGGCTCCCTA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase 1; Arsenical pump modifier 1; Low molecular weight protein-tyrosine-phosphatase 1 [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKPKVAFICVHNSCRSQMAEALGKLYASDVFDSYSAGTETKPEINQDAVKVVKDLYGVDMNQDQYSKLISELPDIDVVIK
MGCNVACPYLPAKHEEDWGLDDPSGKSQEEFVRTAREIERKVKDLAQRIEQGEIELN

Sequences:

>Translated_137_residues
MKPKVAFICVHNSCRSQMAEALGKLYASDVFDSYSAGTETKPEINQDAVKVVKDLYGVDMNQDQYSKLISELPDIDVVIK
MGCNVACPYLPAKHEEDWGLDDPSGKSQEEFVRTAREIERKVKDLAQRIEQGEIELN
>Mature_137_residues
MKPKVAFICVHNSCRSQMAEALGKLYASDVFDSYSAGTETKPEINQDAVKVVKDLYGVDMNQDQYSKLISELPDIDVVIK
MGCNVACPYLPAKHEEDWGLDDPSGKSQEEFVRTAREIERKVKDLAQRIEQGEIELN

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15413; Mature: 15413

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKVAFICVHNSCRSQMAEALGKLYASDVFDSYSAGTETKPEINQDAVKVVKDLYGVDM
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
NQDQYSKLISELPDIDVVIKMGCNVACPYLPAKHEEDWGLDDPSGKSQEEFVRTAREIER
CHHHHHHHHHHCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KVKDLAQRIEQGEIELN
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKPKVAFICVHNSCRSQMAEALGKLYASDVFDSYSAGTETKPEINQDAVKVVKDLYGVDM
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
NQDQYSKLISELPDIDVVIKMGCNVACPYLPAKHEEDWGLDDPSGKSQEEFVRTAREIER
CHHHHHHHHHHCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KVKDLAQRIEQGEIELN
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA