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The map label for this gene is cobH [H]

Identifier: 188585555

GI number: 188585555

Start: 985424

End: 986038

Strand: Reverse

Name: cobH [H]

Synonym: Nther_0927

Alternate gene names: 188585555

Gene position: 986038-985424 (Counterclockwise)

Preceding gene: 188585556

Following gene: 188585553

Centisome position: 31.15

GC content: 37.72

Gene sequence:

>615_bases
ATGACTAAACTACAACCGCAAGAAATAGAAACTAAAAGTATGGAAATCATTCAAAATAAAGTAAATCTATCTGCTTTTAG
TCAAAAAGAATTACCCGTAGTTATGAGAGTGATCCATACTACTGGCGATTTAGAGATACATCGAGATATCAGATTTTCTT
CTAAGGCTGTCACCAAGGGCTTAGAAGCACTAACTGCAGGAGCCGACATTTTCACTGATGTAAATATGGTTACAGCTGGG
CTAAACAAATCTAAACTTAAAAAGCTCGGTTCAAAGATCCATTGTAAAATAGCCGATGAAAATGTGGCAGAAGAGGCTCA
CAGGATTGGAAGCACCAGAGCGGAAACTGCATTTAAAACCTTTGGTGAAAATCTTCATGGAAATATCGTAGTTATCGGAA
ATGCTCCCACAGCTTTATTTAAACTTCTTGAATTAGTTAAAAATCATAACATAACCCCCGCTCTAGTGGTAGGAGTTCCC
GTAGGTTTTGTAGGTGCTAAAGAATCCAAAGATGCATTAATGAACTCCGACTTACCTTATATTTCAATTTCCGGTTATAA
AGGAGGAAGCCCCATAGGGGCCTCCGTTATCAATGCCTTATTGAAATTGCTTTAA

Upstream 100 bases:

>100_bases
CCTGAGAAGACCTTTATTCTGGCAAATCCTATCGGAGAAGATCCTAGATTAATTAAAATCATAGAAAATAGAATAGCTTC
TGCCAAAGGGAGTCAGAAGA

Downstream 100 bases:

>100_bases
CCTGTAATAATCGTGAAAACTATTAAACAACCGTTTTGCGGCATTAATATTTGAAGCCAGGTGTATATGCAAGTAACTAG
CCAGCAGGTTGCCGGATAGG

Product: Precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTKLQPQEIETKSMEIIQNKVNLSAFSQKELPVVMRVIHTTGDLEIHRDIRFSSKAVTKGLEALTAGADIFTDVNMVTAG
LNKSKLKKLGSKIHCKIADENVAEEAHRIGSTRAETAFKTFGENLHGNIVVIGNAPTALFKLLELVKNHNITPALVVGVP
VGFVGAKESKDALMNSDLPYISISGYKGGSPIGASVINALLKLL

Sequences:

>Translated_204_residues
MTKLQPQEIETKSMEIIQNKVNLSAFSQKELPVVMRVIHTTGDLEIHRDIRFSSKAVTKGLEALTAGADIFTDVNMVTAG
LNKSKLKKLGSKIHCKIADENVAEEAHRIGSTRAETAFKTFGENLHGNIVVIGNAPTALFKLLELVKNHNITPALVVGVP
VGFVGAKESKDALMNSDLPYISISGYKGGSPIGASVINALLKLL
>Mature_203_residues
TKLQPQEIETKSMEIIQNKVNLSAFSQKELPVVMRVIHTTGDLEIHRDIRFSSKAVTKGLEALTAGADIFTDVNMVTAGL
NKSKLKKLGSKIHCKIADENVAEEAHRIGSTRAETAFKTFGENLHGNIVVIGNAPTALFKLLELVKNHNITPALVVGVPV
GFVGAKESKDALMNSDLPYISISGYKGGSPIGASVINALLKLL

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21930; Mature: 21799

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQPQEIETKSMEIIQNKVNLSAFSQKELPVVMRVIHTTGDLEIHRDIRFSSKAVTKG
CCCCCCHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
LEALTAGADIFTDVNMVTAGLNKSKLKKLGSKIHCKIADENVAEEAHRIGSTRAETAFKT
HHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHH
FGENLHGNIVVIGNAPTALFKLLELVKNHNITPALVVGVPVGFVGAKESKDALMNSDLPY
HCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCCE
ISISGYKGGSPIGASVINALLKLL
EEECCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
TKLQPQEIETKSMEIIQNKVNLSAFSQKELPVVMRVIHTTGDLEIHRDIRFSSKAVTKG
CCCCCHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
LEALTAGADIFTDVNMVTAGLNKSKLKKLGSKIHCKIADENVAEEAHRIGSTRAETAFKT
HHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHH
FGENLHGNIVVIGNAPTALFKLLELVKNHNITPALVVGVPVGFVGAKESKDALMNSDLPY
HCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCCE
ISISGYKGGSPIGASVINALLKLL
EEECCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732194 [H]